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All Journal Jurnal Ilmu Perairan (Aquatic Science) Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Musyirna Rahmah Nst
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Chemistry Environmental Science Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Isolasi Dan Identifikasi Mikroba Penghasil Antibiotika Dari Sampel Lumpur Sungai Kampar Riau Musyirna Rahmah Nst; Akmal Djamaan; Gustina '
Ilmu Perairan (Aquatic Science) Vol 8, No 2 (2010)
Publisher : Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/jipas.8.2.p.1-11

Abstract

Isolation of microbes that produce antibiotic found in the sludge of Kamparriver has been carrie out using crowded plate method. The sludge were inoculated inPDA and NA, and incubated for 24 hours. Microbes showing clear zone wereobserved, this indicated the microbes produce antibiotics. The microbes wereisolated and identified. The result showed there were three species Bacillus sp ofwhich potencial to produce antibiotic compund.Key words: microbe, isolation,antibiotic
AKTIVITAS SITOTOKSIK EKSTRAK HEKSANA, DIKLOROMETANA DAN METANOL DAUN KEJI BELING (Sericocalyx crispus. L) TERHADAP Artemia salina Leach Musyirna rahmah Nst; Sri Hardianti; Emma Susanti
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Peranan dan Kontribusi Herbal dalam Terapi Penyakit Degeneratif"
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (63.583 KB) | DOI: 10.31942/jiffk.v0i0.382

Abstract

Tumbuhan kejibeling (Sericocalyk crispus L.) merupakan salah satu tanaman yang berpotensi untuk dikembangkan sebagai agen kemopreventif kanker. Tujuan penelitian ini untuk mengetahui efek ekstrak n-heksana, diklorometana dan metanol daun keji beling terhadap Artemia Salina Leach. Uji sitotoksik dilakukan dengan metoda Brine Shrimp Lethality Test (BSLT). Hasil uji sitotoksik menunjukkan  bahwa ekstrak n-heksana, diklorometana dan metanol daun Keji beling mempunyai efek sitotoksik dengan LC50 33,49 µg/ml, 244,34 µg/ml, 143,88 µg/ml. Kata kunci: Sitotoksik, Keji beling, Brine Shrimp Lethality Test, LC50
ISOLASI DAN UJI AKTIVITAS ANTIBAKTERI SENYAWA METABOLIT SEKUNDER DARI EKSTRAK METANOL DAUN MARPUYAN (Rhodamnia cinerea Jack.) Musyirna Rahmah Nst; Dwi Andreyas; Rahma Dona; Emrizal; Emma Susanti; Ihsan Ikhtiarudin; Rahayu Utami
Jurnal Ilmiah Manuntung Vol 9 No 2 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i2.671

Abstract

A study on isolation and antibacterial activity of secondary metabolites from the methanol extract of Marpuyan (Rhodamnia cinerea Jack.) Leaves on Escherichia coli has been carried out. Isolation was carried out by column chromatography methods. Whereas the antibacterial activity test was carried out using agar diffusion method. The results of the isolation produced 17.9 mg of RC-F13 isolate compound in the form of light yellow crystals, with a melting point of 170-172oC and soluble in methanol. The results of identification of RC- F13 isolate compounds through testing with AlCl3 reagents, positive including the flavonoid group, were strengthened by the results of the UV spectrum and FT-IR spectrum. Based on the results of the UV spectrum, it was seen that the RC- F13 isolate compound showed λ max 353.60, 257.00 and 209.20 nm. The FT-IR spectrum shows the presence of several functional groups such as OH, C aliphatic C-H, C = O carbonyl, C = C aromatic and C-O. testing the antibacterial activity of methanol extract with a concentration of 20%; 10%; 1%; 0.1% and 0.01%, fraction 13 at 1% concentration; 0.1% and 0.01% and RC- F13 isolate compound concentration of 0.1%, against Escherichia coli bacteria did not show any antibacterial activity which was marked by the absence of clear areas around the disc.
Co-Authors Akmal Djamaan Dwi Andreyas Emma Susanti Emrizal Gustina ' Ihsan Ikhtiarudin Rahayu Utami Rahma Dona Sri Hardianti Tri Budhi Murdiati