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Uji Aktivitas Antidiabetes Ekstrak Etanol dari Akar dan Batang Tumbuhan Sekunyit (Fibraurea Tinctoria Lour) Utami, Rahayu; Sandi, Nofri Hendri; Hasti, Syilfia; Delvia, Sutri
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 7, No 4 (2015)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sekunyit (Fibraurea tinctoria Lour) is a species plant that has been used as traditional medicine for treating several diseases including jaundice, dysentery, headache, eye infection as well as anti diabetic drug. This research aims to evaluate antidiabetic activity of ethanol extract of roots and stem of sekunyit on white male mice (Mus musculus L) using glibenclamide as positive control. The experimental animals were induced with alloxan 175 mg/Kg BW i.p and devided into six groups, each group consisted of five mice. Group one served as negative control which was given NaCMC 1%, group second was positive control, given  glibenclamide 0,65 mg/KgBW, while group third, fourth, fifth were administered orally with etanol extract with doses of 100, 200 and 300 mg/KgBW, respectively. The observed parameter were measurement of blood glucose levels, urine volume and volume of drinking water as well as ratio of relative organ weight. The treatment was conducted for 15 days. The result showed that administration of ethanol extract of roots and stem of sekunyit can lowered significantly blood glucose levels (p<0,05) of alloxan induced-diabetic mice, decreased urine volume (p<0,05), decreased volume of drinking water (p<0,05), and did not affect relative organ weight of heart, liver and kidney (p>0,05).
Uji Aktivitas Antidiabetes Ekstrak Etanol dari Akar dan Batang Tumbuhan Sekunyit (Fibraurea Tinctoria Lour) Utami, Rahayu; Sandi, Nofri Hendri; Hasti, Syilfia; Delvia, Sutri
Jurnal Farmasi Indonesia Vol 7, No 4 (2015)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (382.003 KB) | DOI: 10.35617/jfi.v7i4.198

Abstract

Sekunyit (Fibraurea tinctoria Lour) is a species plant that has been used as traditional medicine for treating several diseases including jaundice, dysentery, headache, eye infection as well as anti diabetic drug. This research aims to evaluate antidiabetic activity of ethanol extract of roots and stem of sekunyit on white male mice (Mus musculus L) using glibenclamide as positive control. The experimental animals were induced with alloxan 175 mg/Kg BW i.p and devided into six groups, each group consisted of five mice. Group one served as negative control which was given NaCMC 1%, group second was positive control, given  glibenclamide 0,65 mg/KgBW, while group third, fourth, fifth were administered orally with etanol extract with doses of 100, 200 and 300 mg/KgBW, respectively. The observed parameter were measurement of blood glucose levels, urine volume and volume of drinking water as well as ratio of relative organ weight. The treatment was conducted for 15 days. The result showed that administration of ethanol extract of roots and stem of sekunyit can lowered significantly blood glucose levels (p<0,05) of alloxan induced-diabetic mice, decreased urine volume (p<0,05), decreased volume of drinking water (p<0,05), and did not affect relative organ weight of heart, liver and kidney (p>0,05).
PEMERIKSAAN RESIDU ANTIBIOTIK PADA HATI KERBAU DAN IKAN NILA DENGAN METODA DIFUSI AGAR Musyirna Rahmah NST; Rahayu Utami; Nur Rahmadani Fitri
Jurnal Peternakan Vol 7, No 1 (2010): Februari 2010
Publisher : State Islamic University of Sultan Syarif Kasim Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24014/jupet.v7i1.466

Abstract

This study was aimed to identify antibiotic residue on buffalo liver (Bubalus bubalis) dan nila fish (Oreochromis niioticus). Detection of antibiotic residu was used antibacterial assay by diffusion methode. The result indicated that some of samP/i:.s at concentration 25% contained antibiotic residue with inhibited growth rate Escherichia coli 12,3 nun.
Penetapan Kadar Berberin dari Ekstrak Etanol Akar dan Batang Sekunyit (Fibraurea Tinctoria Lour) dengan Metode KCKT Rahayu Utami; Armon Fernando; Indah Puspita Sari; Mustika Furi
Jurnal Sains Farmasi & Klinis Vol 3, No 2 (2017): J Sains Farm Klin 3(2), Mei 2017
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (344.887 KB) | DOI: 10.29208/jsfk.2017.3.2.84

Abstract

Determination of berberine content of ethanol extract of root and stem of “sekunyit” (Fibraurea tinctoria Lour) has been conducted. “Sekunyit” is one of medicinal plant that has been used to treat several diseases traditionally. Its root and stem could relieve jaundice, diarrhea, conjunctivitis as well as antidiabetic agent. Based on previous study, it is known that Fibraurea tinctoria contains isoquinoline alkaloid, berberine. This present study aims to determine berberine content which was done by HPLC (High Performance Liquid Chromatography) method using C-18 reverse phase column, methanol : phosphate buffer (pH 6,8) as its mobile phase with flow rate of 1 ml/min and UV detector. The analysis was performed at wavelength 346 nm. The result showed that the ethanol extract contains 25.8% of berberine
GAMBARAN PERILAKU MASYARAKAT TENTANG PENGGUNAAN MULTIVITAMIN DI APOTEK-APOTEK KOTA PEKANBARU SELAMA PANDEMI COVID-19 Fina Aryani; Fitri Primawanty; Rahayu Utami; Mustika Furi
Jurnal Penelitian Farmasi Indonesia Vol 12 No 1 (2023): JPFI
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (P3M) Sekolah Tinggi Ilmu Farmasi Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v12i1.1738

Abstract

Telah dilakukan penelitian tentang gambaran perilaku masyarakat tentang penggunaan multivitamin di apotek-apotek kota pekanbaru selama pandemi COVID-19. Penelitian ini bertujuan untuk mengetahui gambaran perilaku masyarakat tentang penggunaan multivitamin di apotek-apotek Kota Pekanbaru selama pandemi COVID-19. Penelitian ini merupakan penelitian deskriptif dengan pengumpulan data secara concurrent melalui pengisian kuesioner online. Teknik pengambilan sampel dalam penelitian ini dilakukan secara non probability sampling dengan metode purposive sampling. Sampel yang menjadi penelitian ini adalah sebanyak 110 responden yang memenuhi kriteria inklusi. Responden penelitian yang memenuhi kriteria inklusi diberikan link kuesioner online yang kemudian diisi oleh responden, kemudian data tersebut diolah dan dianalisis. Berdasarkan hasil penelitian menunjukkan bahwa masyarakat yang memiliki perilaku baik sebanyak 21,81%, masyarakat yang memiliki perilaku cukup adalah sebanyak 74,54%, dan masyarakat yang memiliki perilaku kurang adalah sebanyak 3,63%. Perilaku baik di dominasi oleh responden dengan rentang usia 17-25 tahun, jenis kelamin perempuan, pendidikan tinggi dan status pekerjaan bekerja. Research has been carried out on the description of people's behavior regarding the use of multivitamins in Pekanbaru city pharmacies during the COVID-19 pandemic. This study aims to describe people's behavior regarding the use of multivitamins in Pekanbaru city pharmacies during the COVID-19 pandemic. This study used descriptive design with a concurrent data collection method through filling out online questionnaires. The sampling technique in this study was carried out by non-probability sampling with a purposive sampling method. The sample in this study was 110 respondents who met the inclusion criteria. Research respondents who meet the inclusion criteria are given an online questionnaire link which is then filled in by the respondent, then the data is processed and analyzed by the researcher. Based on the results of the study showed that people who have good behavior are 21.81%, people who have sufficient behavior are 74.54%, and people who have less behavior are 3.63%. Good behavior is dominated by respondents with an age range of 17-25 years, female gender, higher education, and work status.
Aktivitas Antibakteri dan Antijamur Fraksi Etil Asetat Kulit Buah Jeruk Manis (Citrus sinensis (L.) Osbeck) Octaviani, Melzi; Masnun, Lidiatil; Nasution, Musyirna Rahmah; Susanti, Emma; Utami, Rahayu; Furi, Mustika
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 15 No. 2 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v15i2.140

Abstract

The sweet orange (Citrus sinensis (L.) Osbeck) is a popular fruit. The part of the sweet orange that is consumed is only the fruit flesh, while the orange peel is only thrown away and not utilized. The sweet orange peel contains several secondary metabolites, namely alkaloids, flavonoids, tannins, phenols, saponins, and steroids, which have antimicrobial properties. This study aims to determine the effect of the concentration of the ethyl acetate fraction of sweet orange peel on antibacterial and antifungal activity in Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Salmonella typhi, and Candida albicans fungi using the disc diffusion method. The ethyl acetate fraction was prepared in several concentration series, namely 50%, 25%, 12.5%, 6.25%, 3.125%, and 1.5625% w/v. The results obtained showed that all concentrations of the ethyl acetate fraction series showed activity in inhibiting the growth of Salmonella typhi bacteria. Series concentrations of 3.125% to 50% have activity in inhibiting the growth of Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Candida albicans fungi. The results of the data analysis using statistical one-way ANOVA showed that the antibacterial and antifungal activities between the concentration series were significantly different (p<0.05) from the negative control.
UJI AKTIVITAS ANTIOKSIDAN DAN TABIR SURYA EKSTRAK ETANOL DAN FRAKSI DAUN TERAP (Artocarpus odoratissimus Blanco) Furi, Mustika; Feriansyah, Robby; Fadhli, Haiyul; Utami, Rahayu; Lestari, Putri
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 15 No. 2 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v15i2.159

Abstract

Plants from genus Artocarpus are known containing phenolic and flavonoid compounds that have potential as antioxidant and sunscreen agent. Terap is one of species plant of Artocarpus genus, which has latin name Artocarpus odorratissimus Blanco. This present study aims to determine the antioxidant and sunscreen activity of ethanol extract and fractions of terap’s leaves. The evaluation was conducted by in vitro assay, which were the antioxidant activity was tested using the DPPH method by Microplate Reader and the sunscreen activity was analyzed using UV-Vis spectrophotometer. The results indicated that ethanol extract, ethylacetate and butanol fractions afforded very strong category of antioxidant activity with IC50 values ​​of 44.04; 42.9 and 36.49 µg/mL, respectively, while moderate activity gave by n-hexane fraction with IC50 value of 168.31 µg/mL. As for the sunscreen activity test, the most potential activity exhibited by the ethylacetate fraction at tested concentrations of 500; 250; 200; and 150 µg/mL demonstrated SPF values of 39.45; 37.36; 33.27 and 26.14, respectively; with ultra protection category as well as showed %Te and %Tp values of <1% which categorized as sunblock.
Penggunaan Metode Dempster Shafer untuk Mendiagnosa Penyakit Varicella Zoster Rahayu Utami; Novriyenni Novriyenni; Rusmin Saragih
Switch : Jurnal Sains dan Teknologi Informasi Vol. 2 No. 5 (2024): September : Switch: Jurnal Sains dan Teknologi Informasi
Publisher : Asosiasi Riset Teknik Elektro dan Informatika Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/switch.v2i5.221

Abstract

Varicella Zoster or known as chickenpox is an infectious disease caused by the Varicella Zoster virus (VSV). Chickenpox is a worldwide airbone disease. Transmission of Varicella zoster is through the air which spreads through coughing and sneezing and also through direct contact with skin lesions. This varicella disease is less of a concern for the public because of the assumption of the public that Varicella Zoster will heal on its own. Where there should be a consultation media and knowledge that can be used by the community in the prevention of varicella disease early on children. So that not every patient brought to the hospital was found to be a patient who had been infected for several days until it was severe to be treated and treated for Varicella Zoster disease. Varicella zoster disease consists of firepox (shingles) which is a follow-up infection of the virus that causes chickenpox. Chickenpox is a viral infection that causes itching on the skin and is characterized by a rash or red spots filled with fluid called elastic. The Dempster Shafer Method is the Dempster Shafer Method, which is a mathematical theory to prove based on belief function and plausibility. Belief indicates a measure of the strength of evidence in supporting a hypothesis, while plausibility indicates a state of trustworthiness. Based on the weight value given by experts on each Varivcella Zoster disease symptom data, from the results of the analysis carried out in the previous chapter, the results of the diagnosis of Varicella Zoster with the type of firepox disease (Herpes Zoster) with a density value of 98.08% were obtained. Keywords: Dempster Shafer, Diagnosis, Varicella Zoster
Peran Bimbingan Konseling Pada Siswa Inklusi di SMP Muhammadiyah 1 Kartasura Rachmawati, Fatkur; Faisya Abrari Lutrinda; Yayuk Riana; Nurul Asma Khoiriyah; Ilham Nur Safitri; Rahayu Utami; Mahasri Shobabiya
TAUJIH: Jurnal Pendidikan Islam Vol 6 No 02 (2024): Taujih: Jurnal Pendidikan Islam
Publisher : Program Studi Pendidikan Agama Islam IAIQI Al-Qur'an Al-Ittifaqiyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53649/taujih.v6i02.974

Abstract

This study aims to identify the role of Guidance and Counseling for inclusive children at SMP Muhammadiyah 1 Kartasura. Inclusion is a special education service for every child with special needs. Of course, it is one of the responsibilities of a guidance and counseling teacher at a school, especially at SMP Muhammadiyah 1 Kartasura, which is known that SMP Muhammadiyah 1 Kartasura is one of the schools that accepts inclusive students. From the data obtained, SMP Muhammadiyah 1 Kartasura has eight inclusive students, namely five students with a companion teacher for each student, and three students without a companion teacher. This study uses a qualitative methodology with a phenomenological approach taken from interviews with related BK teachers. Then the data is analyzed through interactive analysis. The results of this study are that BK teachers have an important role in helping inclusive students, including being the coordinator of each companion teacher, taking an approach to help inclusive students develop their potential, both in academic and social fields. The inhibiting factor for the role of guidance and counseling for inclusive students is the lack of assistance for some students due to parental disagreement. However, this is supported by inclusive students in this junior high school who show good development in socializing. Socialization efforts carried out by teachers regarding students with special needs (ABK) help non-inclusive students to understand and accept inclusive students, creating an inclusive and friendly environment for all students.
HUBUNGAN PENYESUAIAN DIRI DENGAN PSYCHOLOGICAL WELL-BEING PADA IBU YANG MEMILIKI ANAK INTELLECTUAL DISABILITY DI KOTA PADANG Elza, Bunga; Ulandari, Bunga; Utami, Rahayu
CAUSALITA : Journal of Psychology Vol 2 No 2 (2024): CAUSALITA: Journal of Psychology
Publisher : CV. Causalita Dynamic Solutions

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62260/causalita.v2i2.324

Abstract

Orangtua yang mempunyai anak intellectual disability kerap kali mengahadapi tekanan psikologis yang lebih besar terutama ibu. Oleh karena itu, perlu dilakukan penyesuaian diri untuk mengatasi stres yang dirasakan pada ibu dengan anak intellectual disability. Studi ini bermaksud guna mengidentifikasi hubungan antara penyesuaian diri dengan psychological well-being pada ibu dengan anak intellectual disability di Kota Padang. Studi ini memakai strategi penelitian kuantitatif berdasarkan metodologi korelasional. Sebanyak 37 sampel diambil dari populasi ibu-ibu berdomisili di Kota Padang yang memiliki anak berkebutuhan khusus. Sampel diambil dengan memakai strategi purposive sampling.  Teknik Product Moment Correlation dipakai guna menganalisis data. Temuan studi memperlihatkan bahwasanya Ha diterima dan H0 ditolak, dengan koefisien korelasi sebesar 0,812 dan tingkat signifikansi 0,000 < 0,05. Ini berarti adanya hubungan positif dan signifikan antara variabel penyesuaian diri dengan variabel psychological well-being pada ibu yang punya anak intellectual disability di kota Padang. Selain itu penyesuaian diri memiliki sumbangan afektif sebesar 65,9% dalam terciptanya psychological well-being pada ibu dengan anak intellectual disability di kota padang. 
Co-Authors Afandi, Rifath Ainun Alfatma Alhabil, Laras Allaya, Regina Alpasiri, Ikhsan Mauludi Andrea, Kamilah Dzikra Andriani, Sindy Anggraini, Hadistri Sekar anissa, Siti nurul Annur, Isnaini Ardiyansyah, Roni Armon Fernando Armon Fernando Arsila, Sherly Putri Asmarani, Asmarani Aulia Fitri, Aulia Azzahra, Fayza Salwa A’dilah, Nur Burhan, Shafira Ilma Chehdimae, Hamdan Delvia, Sutri Delvia, Sutri Dwi Andreyas Elza, Bunga Emma Susanti Emrizal Enda Mora Eva Nurhasanah Fahri, Elifia Cahyani Faisya Abrari Lutrinda Fazira, Intan Febbyola, Flara Ferdy Firmansyah Feriansyah, Robby Fina Aryani, Fina Fitri Primawanty Furi, Mustika Haiyul Fadhli Hanifa, Dhea Husnawati Ihsan Ikhtiarudin Ilham Nur Safitri Indah Puspita Sari Jumadila, Ikhsal Mukri M Almurdani Mahasri Shobabiya Masnun, Lidiatil Melzi Octaviani Miftahul Jannah Milianty, Jesy Mira Febriana Muhammad Wildan Shohib Musyirna Rahmah Nasution Musyirna Rahmah Nst Nasution, Musyirna Rahmah Nofri Hendri Sandi Nofriyanti Nofriyanti Novianti, Yetri Novriyenni Novriyenni Nur Rahmadani Fitri Nurul Asma Khoiriyah Oriendhini, Salsa Patmawati, Lilis Three Pitri, Siska Dian Pratama, Hafizh Yandi Pratiwi1, Tri Ningtiyas Putri Lestari, Putri Putri Zulnandita Rachmawati, Fatkur Rahayu, Adnin Rahma Dona Rahmayanı, Wıky rambe, Septy amelia rizki Rasihen, Sri Lidya Rizki Wulandari Rizkia, Tiara Rusmin Saragih, Rusmin Safitri, Rahtu Janese Safli, Fazza Aulia Salsabila, Helmaria Putri Septi Muharni Septi Muharni Silalahi, Rizka Fitri Sirait, Indri Hotma Novida Siti Nurhaliza Syilfia Hasti T, Febry Sesilia Tambunan, Beatrix Evalin Ulandari, Bunga Ulfa, Rodia Utami, Adinda Abia Wahidah, Lutfiana Nurul Wira Noviana Suhery Yani, Halijah Putri Yanto, Rizki Dwi Yayuk Riana