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All Journal Jurnal Farmasi Indonesia Psikosains: Jurnal Penelitian dan Pemikiran Psikologi
Dzulkifli Dzulkifli
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Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology Medicine & Pharmacology Neuroscience Physics Social Sciences Other

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Uji Toksisitas Subakut Ekstrak Etanol Daun Asam Jawa Dosis Efektif Sebagai Antihiperglikemia Terhadap Kadar AST, ALT, dan Kreatinin Tikus (Rattus norvegicus) Sitti Rahimah Rachman; Dzulkifli Dzulkifli; Suwahyuni Suwahyuni; Rahmad Aksa; Mirnawati Salampe; Akbar Awaluddin
Jurnal Farmasi Indonesia Vol 18 No 1 (2021): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v18i1.1096

Abstract

The toxicity test is one of the pharmacological testing stages that must be carried out to assess the use of a drug. Research on the activity test of the ethanol extract of Tamarind leaves (Tamrindus indica L) at a dose of 14 mg / 200 g BW as an antihyperglycemia in experimental animals gave results that were not significantly different from the standard drug activity of Glibenclamide as an antidiabetic mellitus, so this study was conducted with the aim of looking at the ethanol of tamarind leaves. (Tamrindus indica L) for 30 days on levels of the enzymes AST, ALT, and creatinine in rats (Rattus norvegicus). This sub-acute toxicity test used 14 test animals divided into 2 groups, each group consisting of 7 rats. Group I was given 0.5% Na CMC treatment as a control and group II was treated with the ethanol extract of tamarind leaves at a dose of 14 mg / 200 g BW for 30 days. On the 31st day, blood serum measurements were taken with AST, ALT and creatinine parameters using a humalyzer. The results of the subacute toxicity test showed that giving tamarind leaves ethanol extract as an antihyperglycemia did not cause an increase in the AST, ALT AND creatinine enzymes beyond normal limits.
EFEKTIFITAS APE “RUMAH EDUKASI” TERHADAP KEMAMPUAN KONSEP DASAR HITUNG DAN MENGENAL WAKTU PADA SISWA TAMAN KANAK-KANAK Rinanti Resmadewi; Dzulkifli Dzulkifli
PSIKOSAINS (Jurnal Penelitian dan Pemikiran Psikologi) Vol. 20 No. 1 (2025)
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/psikosains.v20i1.8978

Abstract

Background: The Education House is a learning media in the form of an Educational Game Tools (EGT) which aims to train children in the ability to think logically, increase creativity, and train children's fine motor skills. This game is divided into three kinds, namely games in counting, guessing pictures, and knowing the time by pointing the clock. Objective: to see whether APE is effective in improving the ability to count and recognize time in Aisyiyah Kindergarten students Method: This study used quantitative methods and the research design used was experimental research (one group pretest-posttest design). The research subjects were students of TK Aisyiyah Bustanul Athfal 58, TK Aisyiyah Bustanul Athfal 6, and TK Aisyiyah Bustanul Athfal 47 Surabaya. The data collection technique used in this study was by giving pre-test and post-test questions. Result: after the researchers gave the treatment twice using the EGT "Education House" that the researchers made, the results showed that the subjects experienced an increase in their basic ability to count and recognize time. Conclution: effective EGT can improve numeracy skills and know time in Aisyiyah Kindergarten students.
Co-Authors Akbar Awaluddin Mirnawati Salampe Rahmad Aksa Rinanti Resmadewi Sitti Rahimah Rachman Suwahyuni Suwahyuni