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Uji Toksisitas Subakut Ekstrak Etanol Daun Asam Jawa Dosis Efektif Sebagai Antihiperglikemia Terhadap Kadar AST, ALT, dan Kreatinin Tikus (Rattus norvegicus) Sitti Rahimah Rachman; Dzulkifli Dzulkifli; Suwahyuni Suwahyuni; Rahmad Aksa; Mirnawati Salampe; Akbar Awaluddin
Jurnal Farmasi Indonesia Vol 18 No 1 (2021): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v18i1.1096

Abstract

The toxicity test is one of the pharmacological testing stages that must be carried out to assess the use of a drug. Research on the activity test of the ethanol extract of Tamarind leaves (Tamrindus indica L) at a dose of 14 mg / 200 g BW as an antihyperglycemia in experimental animals gave results that were not significantly different from the standard drug activity of Glibenclamide as an antidiabetic mellitus, so this study was conducted with the aim of looking at the ethanol of tamarind leaves. (Tamrindus indica L) for 30 days on levels of the enzymes AST, ALT, and creatinine in rats (Rattus norvegicus). This sub-acute toxicity test used 14 test animals divided into 2 groups, each group consisting of 7 rats. Group I was given 0.5% Na CMC treatment as a control and group II was treated with the ethanol extract of tamarind leaves at a dose of 14 mg / 200 g BW for 30 days. On the 31st day, blood serum measurements were taken with AST, ALT and creatinine parameters using a humalyzer. The results of the subacute toxicity test showed that giving tamarind leaves ethanol extract as an antihyperglycemia did not cause an increase in the AST, ALT AND creatinine enzymes beyond normal limits.
PKM Pada Masyarakat Kawasan Aditarina Makassar: Jajanan Sehat Maria Ulfa; Reny Syahruni; Suwahyuni Suwahyuni; Michrun Nisa; Tuti Handayani; Wahyu Hendrarti; Lukman Muslimin; Andi Paluseri; Yuri Pratiwi; Nur Khairi
Jurnal Pengabdian Kefarmasian Vol 3, No 1 (2022): JURNAL PENGABDIAN KEFARMASIAN
Publisher : Jurusan Farmasi Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/jpk.v3i1.2829

Abstract

Dedicated to Community in The Aditarina Makassar: Clean and Healthy Living BehaviorThe area of Aditarania Mosque, Manggala District, Makassar City is an area dominated by the lower middle level community with scavenger professions, there are many school-aged children with low levels of parental knowledge and children on clean and healthy snacks. This service activity aims to provide knowledge and information to the people of the Aditarina region on the importance of consuming healthy snacks. Activities are conducted both offline and audaciously with the lecture and discussion methods. The advice material provided includes the characteristics of healthy snacks, all the harmful ingredients that are often added to snacks, and how to choose healthy snacks. The results of service activities provide the community with increased knowledge about healthy, clean, and safe services.Keywords: Aditarania, snacks, hazardous materials.Kawasan mesjid aditarania Kecamatan Manggala Kota Makassar merupakan kawasan yang didominasi oleh masyarakat tingkat ekonomi menengah kebawah dengan profesi pemulun, terdapat banyak anak-anak usia sekolah dengan tingkat pengetahuan orang tua dan anak yang rendah terhadap jajanan yang bersih dan sehat. Kegiatan pengabdian ini bertujuan untuk memberikan pengetahuan dan informasi kepada masyarakat kawasan Aditarina tentang pentingnya mengkonsumsi jajanan yang sehat. Kegiatan yang dilakukan secara hybrid gabunganluring maupun daring dengan metode ceramah, dan diskusi. Materi penyuluhan yang diberikan meliputi cirri-ciri jajanan yang sehat,bahan-bahan berbahaya apasaja yang sering ditambahakan pada jajanan serta cara memilih jajanan yang sehat. Hasil Kegiatan pengabdian telah memberikan peningkatan pengetahuan kepada masyarakat tentang jajanan yang sehat,bersih dan aman.Kata Kunci : Aditarania,jajanan,bahan berbahaya.