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Journal : Journal of Local Therapy

FORMULATION AND TESTING OF ANTIBACTERIAL ACTIVITY OF FACIAL TONER PREPARATIONS CHINESE BELT LEAF EXTRACT (Peperomia pellucida L. Kunth) AGAINST THE BACTERIA Propionibacterium acnes Nasikin, M. Ali; Ridlo, Achmad; Rakhmayanti, Regia Desty; Hapsari, Azizah Nur
Journal of Local Therapy Vol 3 No 2 (2024): Journal of Local Therapy
Publisher : Pusat Unggulan IPTEK Poltekkes Kemenkes Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31290/jlt.v3i2.4674

Abstract

Abstract: Chinese betel leaf (Peperomia pellucida L.Kunth) is a herbal plant that can be used to treat abscesses, acne, boils and skin inflammation. Chinese betel leaves contain chemical compounds including alkaloids, flavonoids, saponins, tannins and triterpenoids which can inhibit the growth of Propionibacterium acnes bacteria. The Chinese betel leaf extract content can be used as a refreshing toner, especially for dry and acne-prone skin. The aim of this research is to determine the results of physical quality tests and antibacterial activity of Chinese betel leaf extract facial toner formulations with an additional active ingredient concentration of 7.5%; 15% and 30%. This type of research is experimental research with a descriptive research design. The organoleptic test results of the base are clear and odorless, while the other 3 formulas are brownish green in color, have a distinctive aroma of Chinese betel leaf extract and are in liquid form. The homogeneity test results of the preparation are homogeneous. F0 pH test results 6.327; FI 5.344; FII 5,243 and FIII 5,067. Viscosity test results F0 5.32 cps FI 6.34 cps and FII 6.33 cps. The results of the antibacterial activity test F0, FI, FII, and FIII were respectively 0.00 mm, there was no inhibition zone, 7.37 mm, 13.35 mm, 16.24 mm and in the positive control clindamycin it was 21.17 mm. Based on the results of the physical quality test and antibacterial activity of the toner preparation, the toner preparation has met existing quality standards so it is safe to use and the toner preparation with the strongest antibacterial activity is found in FIII.
DETERMINATION OF PHENOL CONTENT AND PHYSICAL TEST OF COMBINED JAMU POWDERRED GINGER (Zingiber officinale Rosc. var. rubrum), KENCUR (Kaempferia galanga L.) AND TURMERIC (Curcuma domestica Val.) Rusita, Youstiana Dwi; Ridlo, Achmad; Nasikin, M. Ali; Wijayanti, Ayu Rizki
Journal of Local Therapy Vol 3 No 2 (2024): Journal of Local Therapy
Publisher : Pusat Unggulan IPTEK Poltekkes Kemenkes Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31290/jlt.v3i2.4673

Abstract

Abstract: Powdered herbs are in the form of fine grains ground from sifted simplicia, blended with different compositions adjusted to the function and benefits of the herb, powdered herbs are consumed by brewing with warm water. This study was to determine the organoleptic physique, pH, moisture content, weight uniformity, and phenol content of herbal medicine powder in combination with red ginger (Zingiber officinale Rosc. var. rubrum), kencur (Kaempferia galanga L.) and turmeric (Curcuma domestica Val.). The method used to measure pH was using a pH meter, the moisture content using the gravimetric method, the phenol level using the foline ciocalteau method with the standard standard of gallic acid. The organoleptic results of herbal powder are in the form of powder, the taste in composition 1 is a bit bitter, in composition 2 the typical bitterness of turmeric is a little spicy, and in composition 3 it is a bit bitter. The pH results of composition 1, 2 and 3 were 5.954, 6.088 and 6.105. The results of the moisture content of composition 1, 2 and 3 were 8.1639, 6.8732 and 8.1042 respectively. The result of the uniformity of the weight of the second composition is 15% red ginger, 40% kencur, 45% turmeric.