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All Journal Medula Damianus Journal of Medicine Medicinus : Jurnal Kedokteran Jurnal Epidemiologi Kesehatan Indonesia Jurnal Syntax Fusion : Jurnal Nasional Indonesia Prosiding Konferensi Nasional PKM-CSR
Nicolaski Lumbuun
Department Of Pharmacology, University Of Indonesia, School Of Medicine, Jakarta
Humanities Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Long term side effects of methylphenidate hydrochloride in childhood ADHD in primary care: An evidence-based case report Andoko, Dewanto; Lumbuun, Nicolaski; Cipta, Darien
Bahasa Indonesia Vol 23 No 3 (2024): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v23i3.4743

Abstract

Background: Attention Deficit Hyperactivity Disorder (ADHD) often emerges in childhood and can persist into adolescence and adulthood. Methylphenidate is the primary medication for managing ADHD in youth, but its long-term effects remain uncertain. Evaluating the evidence on the long-term effects of methylphenidate in children with ADHD is crucial. Case: A 7-year-old with school difficulties, hyperactivity, and distractibility (Conner's score 22) was diagnosed with ADHD and treated with methylphenidate. Significant behavioral improvement was observed (Conner's score 8), but parental concerns regarding long-term medication use persisted. Metode: We conducted a structured search in PubMed, EBSCOhost, Cochrane, and SAGE databases, focusing on the past 5 years of English-language human studies with full-text availability. We selected randomized control trials (RCTs), meta-analyses, and systematic reviews and screened them based on relevance to our clinical question. The search yielded results from PubMed (43 articles), EBSCOhost (46 articles), Cochrane (41 articles), and SAGE (125 articles). After rigorous screening, some articles were identified as relevant. Conclusion: Our case analysis based on evidence revealed that methylphenidate treatment is associated with serious and non-serious side effects, irrespective of treatment duration. Primary care clinicians should exercise caution when prescribing methylphenidate for ADHD management in childhood.
The Effect of Light Colour During Night Time to Sleep Quality Sylvanus, Peter; Lumbuun, Nicolaski
Medicinus Vol. 9 No. 3 (2020): June 2020
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v8i1.3123

Abstract

Introduction: Sleep is one of the basic human needs, where human uses one third of their time only for sleeping. Some contributing factors towards bad sleep quality are stress, depression, surrounding noise, and the use of a bright light. It is known that white lights cause the activation of melanopsin, causing circadian cycle shift, whereas using yellow light does not. The aim of this research was to analyze whether there is an effect of using either white or yellow light towards sleep qualityMethod: This is RCT on 81 subjects. Sleep quality was measured using PSQI questionnaire on 3 measurements with each measurement taken every week. Result of the analyzed data using the General Linear Model - Repeated Measurement (GLM-RM) method Result: There were significant differences on PSQI score between group that used white light during sleep (7.6 ± 2.3) in comparison to the control group (5.2 ± 1.8) (p = 0.02), but result also showed that there were no significant difference between the group that used yellow light (6.1 ± 1.7) during sleep in comparison with the control group (p = 0.14). Conclusion: There is a significant difference between the uses of white lights during sleep towards sleep quality, but there has not been any significant difference between the uses of yellow light during sleep towards sleep quality
Characteristics of NSAIDs Prescription in Elderly Knee Osteoarthritis Patients Wong, Janetta; Lumbuun, Nicolaski
Medicinus Vol. 11 No. 3 (2022): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v10i1.6988

Abstract

Introduction: The prescribing of non-steroidal anti-inflammatory drugs (NSAIDs) as pharmacological therapy for OA was found to be imprecise. In 2018, the rationality of NSAIDs prescribed at Wolter Monginsidi Hospital, Manado showed as much as 100% proper indication, 77% proper dose, and 89% proper medication. This shows that the rationality of NSAIDs prescription is still irrational. Irrational prescribing has the potential to result in side effects or the incidence of drug-related problemsAim: To determine the characteristics and the rationality of NSAIDs prescriptions in elderly knee OA.Methods: This is a descriptive study of 108 medical records for the period January 2020-April 2021 at BS Clinic, Semarang, using purposive sampling method.Result: Results showed the characteristics of elderly knee OA patients at BS Clinic were 74.1% women, 47.2% belonging to obese group, and 41.7% experiencing severe pain. Patient’s age had a median value of 66 years. In the number of comorbidity, the median value was 1. The rationality of NSAIDs prescription was 95,4% proper diagnosis, 100% proper drug, 97.2% proper dose, and 99.1% proper indication with the incidence of side effects of NSAIDs prescribing was 1.9%.
The Correlation of Insomnia and Anxiety in Students of The Faculty of Medicine, University of Pelita Harapan Dhinata, Kinley; Lumbuun, Nicolaski
Medicinus Vol. 11 No. 3 (2022): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v10i1.6991

Abstract

Background and Aim: Insomnia and anxiety are common disorders with high prevalence rate especially in medical students. Moreover, many confounding factors playing a role in influencing anxiety. Most studies does not include or measure other confounding factors of anxiety into the analysis. This requires research which examines insomnia and anxiety assessing the contribution of the factors influencing anxiety.Methods: A cross-sectional study methodology with linear regression analysis on a sample of students from the Faculty of Medicine, University of Pelita Harapan using the DASS-21 questionnaire to assess anxiety and ISI to assess insomnia.Results: Prevalence rates of insomnia was 34.29% and anxiety 32.38% in Pelita Harapan University medical student. From the results of the bivariate linear regression, a weak relationship between insomnia and anxiety (r = 0.322; p = 0.000) is seen. In multivariate results, there were confounding stress variables (r = 0.565; p= 0.000) and trauma (r = 0.250; p = 0.005) which contributed greatly to anxiety (In order of largest).Conclusion: There is a weak correlation and anxiety. Moreover, high prevalence rate of anxiety in medical students may be contributed heavily not only by insomnia but also stress and childhood trauma.
Co-Authors Andoko, Dewanto Andrew Chandra, Andrew Andri Theja Cipta, Darien Dhinata, Kinley Eka, Ni Gusti Ayu Emilius, Denny Janetta Wong Kinley Dhinata Nasrin Kodim Rumerung, Christie Sinaga, Juniarta Sitanggang, Yenni Ferawati Soeryani, R Wianti Soeryani, R. Wianti Sylvanus, Peter Wong, Janetta