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Journal : Academia Open

Comparison Of The Number Of Leukocytes, Lymphocytes, Monocytes and Neutrophils In Patients with Infectious and Non-Infectious Febriles Shofaroh, Nadiyatul Husna; Ardiansyah, Syahrul
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.7486

Abstract

The examination parameters used to detect febris are leukocytes (WBC), erythrocytes (RBC), hemoglobin (Hb), hematocrit, and platelets. Leukocyte examination is very important to detect the cause of febris. The purpose of this study was to determine the comparison of the number of leukocytes, lymphocytes, monocytes, and neutrophils in patients with infectious and non-infectious febris. This study used a laboratory experimental research design, with quantitative methods. The research subjects were febris patients aged 0-5 years with a total of 60 patients. Data showing a significance value of p=0.000 (p<0.05) means that there is a comparison between the number of infectious and non-infectious febris leukocytes and the number of monocytes shows a significance value of p=0.003 (p<0.05) means that there is a comparison between the number of monocytes of infectious and non-infectious febris patients. While the number of lymphocytes showed a significance value of p=0.482 (p>0.05) meaning that there was no comparison between the number of lymphocytes with febris infection and non-infection, and the number of neutrophils showed a significance value of p=0.287 (p>0.05) meaning that there was no comparison between the number of neutrophils with febris infection and non-infection. Conclusion on the examination of the number of leukocytes, lymphocytes, monocytes, and neutrophils in infectious and non-infectious febris patients, there is a comparison in the number of leukocytes and monists between infectious and non-infectious febris patients. Highlight: Leukocyte exams crucial for febrile diagnosis. Variances in leukocyte and monocyte counts aid distinction. Unique cell count patterns reveal infection types. Keyword: Febris, Leukocytes, Lymphocytes, Monocytes, Neutrophils
Comparison of Fasting Blood Sugar Levels and Ureum Levels In Diabetes Mellitus Patients and Diabetic Nephropathy Patients Ramadhani, Adilla Cahya; Ardiansyah, Syahrul
Academia Open Vol 9 No 1 (2024): June
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.9294

Abstract

General Background: Diabetes Mellitus (DM) is a chronic disease characterized by hyperglycemia. Specific Background: A severe complication of DM is diabetic nephropathy, marked by progressive kidney function decline. Blood sugar and urea levels serve as crucial indicators in diagnosing DM and its complications. Knowledge Gap: Limited comparative studies exist on fasting blood sugar and urea levels between diabetes mellitus patients and diabetic nephropathy patients. Aims: This study aims to compare fasting blood sugar levels and urea levels in diabetes mellitus patients and diabetic nephropathy patients. Results: Conducted from April to June 2024, this quantitative, laboratory experimental study sampled 30 diabetes mellitus patients and 30 diabetic nephropathy patients from RSUD dr. Wahidin Sudiro Husodo, Mojokerto City. Using the SPSS Mann-Whitney test, the study found significant differences (p=0.000) in fasting blood sugar levels (125.20±20.348 mg/dL vs. 221.07±65.545 mg/dL) and urea levels (13.30±2.059 mg/dL vs. 54.10±26.699 mg/dL) between the two patient groups. Novelty: This study provides novel insights into the metabolic differences between diabetes mellitus and diabetic nephropathy patients, emphasizing the progressive impact of high blood sugar on kidney function. Implications: The findings underscore the importance of early intervention and continuous monitoring of blood sugar and urea levels to prevent or mitigate diabetic nephropathy in DM patients. Highlights : Significant Differences: The study found significant differences in fasting blood sugar and urea levels between diabetes mellitus and diabetic nephropathy patients. Metabolic Insights: Provides insights into the metabolic impact of high blood sugar on kidney function in diabetic nephropathy patients. Clinical Implications: Highlights the need for early intervention and continuous monitoring to prevent or mitigate diabetic nephropathy in DM patients. Keywords : Diabetes Mellitus, Diabetic Nephropathy, Fasting Blood Sugar Levels, Urea Levels, Kidney Function