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All Journal PREMISE LAW JURNAL Acta Interna : The Journal of Internal Medicine Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan Journal of Medical Science; Jurnal Ilmu Medis Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh
Julia Sari
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Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health

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Acute Coronary Syndrome in Young Patients at Dr. Sardjito General Hospital Setianto, Budi Yuli; Sari, Julia; Hartopo, Anggoro Budi; Gharini, Putrika Prastuti Ra
Acta Interna The JOurnal of Internal Medicine Vol 4, No 1 (2014): Acta Interna The Journal Of Internal Medicine
Publisher : Acta Interna The JOurnal of Internal Medicine

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Abstract

ABSTRACTBackground: The incidence of acute coronary syndrome in the young patients is increased recently.Several studies reported that young patients have distinct clinical characteristics as compare with olderpatients.Objective: To assess the prevalence, risk factors and clinical presentation of acute coronarysyndrome(ACS) in young patients at Dr. Sardjito Hospital, Yogyakarta.Methods: We conducted a cross sectional study between September 2008-May 2009 at intensivecardiovascular care unit (ICCU) of Dr. Sardjito Hospital. We enrolled consecutive patients admittedwith acute coronary syndrome. We divided the patients as young ACS (age ≤ 45 years) and older ACS(age >45 years). We compared cardiovascular risk factors, clinical presentation and clinical spectrumsfrom both groups. Statistics analysis was performing using chi-square test, p value < 0.05 was consideredsignifi cantly different.Results: In our study there were 20 (13.5%) young ACS and 128 (86.5%) older ACS patients. Mostyoung ACS patients are male (90%). Proportion of diabetes mellitus in young ACS was not differentfrom that in older ACS patients (20% vs. 18.8%; p=0.55). Hypertension was not different either (50%vs. 53.1%; p=0.49). Sixty percent of young ACS patients were smoker, however its proportion did notdiffer from older ACS patients (p=0.84). There were no signifi cant differences of dyslipidemia. Theyoung ACS patients mostly experienced STEMI than NSTEMI and unstable angina (55% vs. 15%vs. 30%), but there were no signifi cant differences when compared to older ACS patients (p=0.65).Thirty percent of young ACS patients presented with Killip class II or higher, however there were nosignifi cant differences between groups (p=0.40).Conclusion: In this study we found that there were no signifi cant differences in risk factors, clinicalpresentation and spectrums between young ACS and older ACS patients. The need for preventionprogram in both groups should not be difference.Keywords: ACS– young– older– clinical presentation.
Acute Coronary Syndrome in Young Patients at Dr. Sardjito General Hospital Setianto, Budi Yuli; Sari, Julia; Hartopo, Anggoro Budi; Ra Gharini, Putrika Prastuti
Acta Interna The Journal of Internal Medicine Vol 4, No 1 (2014): Acta Interna The Journal Of Internal Medicine
Publisher : Acta Interna The Journal of Internal Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (186.819 KB)

Abstract

ABSTRACTBackground: The incidence of acute coronary syndrome in the young patients is increased recently. Several studies reported that young patients have distinct clinical characteristics as compare with older patients.Objective: To assess the prevalence, risk factors and clinical presentation of acute coronary syndrome(ACS) in young patients at Dr. Sardjito Hospital, Yogyakarta.Methods: We conducted a cross sectional study between September 2008-May 2009 at intensive cardiovascular care unit (ICCU) of Dr. Sardjito Hospital. We enrolled consecutive patients admitted with acute coronary syndrome. We divided the patients as young ACS (age ≤ 45 years) and older ACS (age >45 years). We compared cardiovascular risk factors, clinical presentation and clinical spectrums from both groups. Statistics analysis was performing using chi-square test, p value < 0.05 was considered significantly different.Results: In our study there were 20 (13.5%) young ACS and 128 (86.5%) older ACS patients. Most young ACS patients are male (90%). Proportion of diabetes mellitus in young ACS was not different from that in older ACS patients (20% vs. 18.8%; p=0.55). Hypertension was not different either (50% vs. 53.1%; p=0.49). Sixty percent of young ACS patients were smoker, however its proportion did not differ from older ACS patients (p=0.84). There were no signifi cant differences of dyslipidemia. The young ACS patients mostly experienced STEMI than NSTEMI and unstable angina (55% vs. 15% vs. 30%), but there were no signifi cant differences when compared to older ACS patients (p=0.65). Thirty percent of young ACS patients presented with Killip class II or higher, however there were no significant differences between groups (p=0.40).Conclusion: In this study we found that there were no signifi cant differences in risk factors, clinical presentation and spectrums between young ACS and older ACS patients. The need for prevention program in both groups should not be difference.Keywords: ACS– young– older– clinical presentation.
Acute Coronary Syndrome in Young Patients at Dr. Sardjito General Hospital Budi Yuli Setianto; Julia Sari; Anggoro Budi Hartopo; Putrika Prastuti Ra Gharini
Acta Interna The Journal of Internal Medicine Vol 4, No 1 (2014): Acta Interna The Journal Of Internal Medicine
Publisher : Faculty of Medicine Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (186.819 KB) | DOI: 10.22146/acta interna.5728

Abstract

ABSTRACTBackground: The incidence of acute coronary syndrome in the young patients is increased recently. Several studies reported that young patients have distinct clinical characteristics as compare with older patients.Objective: To assess the prevalence, risk factors and clinical presentation of acute coronary syndrome(ACS) in young patients at Dr. Sardjito Hospital, Yogyakarta.Methods: We conducted a cross sectional study between September 2008-May 2009 at intensive cardiovascular care unit (ICCU) of Dr. Sardjito Hospital. We enrolled consecutive patients admitted with acute coronary syndrome. We divided the patients as young ACS (age ≤ 45 years) and older ACS (age >45 years). We compared cardiovascular risk factors, clinical presentation and clinical spectrums from both groups. Statistics analysis was performing using chi-square test, p value < 0.05 was considered significantly different.Results: In our study there were 20 (13.5%) young ACS and 128 (86.5%) older ACS patients. Most young ACS patients are male (90%). Proportion of diabetes mellitus in young ACS was not different from that in older ACS patients (20% vs. 18.8%; p=0.55). Hypertension was not different either (50% vs. 53.1%; p=0.49). Sixty percent of young ACS patients were smoker, however its proportion did not differ from older ACS patients (p=0.84). There were no signifi cant differences of dyslipidemia. The young ACS patients mostly experienced STEMI than NSTEMI and unstable angina (55% vs. 15% vs. 30%), but there were no signifi cant differences when compared to older ACS patients (p=0.65). Thirty percent of young ACS patients presented with Killip class II or higher, however there were no significant differences between groups (p=0.40).Conclusion: In this study we found that there were no signifi cant differences in risk factors, clinical presentation and spectrums between young ACS and older ACS patients. The need for prevention program in both groups should not be difference.Keywords: ACS– young– older– clinical presentation.
EFEKTIVITAS PELAKSANAAN UNDANG-UNDANG NOMOR 2 TAHUN 1960 TENTANG PERJANJIAN BAGI HASIL TANAH PERTANIAN DI DESA UJUNG TERAN KECAMATAN SALAPIAN KABUPATEN LANGKAT JULIA SARI
PREMISE LAW JURNAL Vol 12 (2016): VOLUME XII TAHUN 2016
Publisher : PREMISE LAW JURNAL

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Abstract

The study used judicial emperical and descriptive method which was aimed to generally describe the condition of the implementation of law No. 2/1960 on Production Sharing Agreement on Farm Land at Ujung Teran Village, Salapian Subdistrict, Langkat Regency. The gathered data were analyzed by using judicial sociological method.The result of the study shows that the people at Ujung Teran Village do not know at all about the production sharing regulated in Law No. 2/1960. Therefore, they still comply with and use the adat ( traditional ) law which has developed from generation to generation. The infeasibility of Law No. 2/1960 is not because they are ignorant of the law or low quality of Law No. 2/1960, but because they really do not know about it. In order to uphold the implementation of Law No. 2/1960, it is recommended that the local Government widely inform Law No. 2/1960 to the people through the Village Head as the official which is close to his people. Keyword: Production Sharing Agreement
PENERAPAN MODEL PEMBELAJARAN LANGSUNG UNTUK MENINGKATKAN HASIL BELAJAR IPA PADA SISWA KELAS VB SD NEGERI 004 BAGAN TIMUR Julia Sari; Mahmud Alpusari
Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan Vol 5, No 1 (2018): WISUDA APRIL 2018
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan

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Abstract: This study was conducted to determine the learning outcome of students by implementing Direct Learning. This research was done in class VB SD Negeri 004 Bagan Timur. This research is a classroom action research conducted in two cycles of planning, implementation, observation and reflection. The data collected in this study is teacher's activities, student activities and the student learning outcomes. Data were collected using a written test and observation sheet. The results of the analysis and discussion show the teacher activity, student activity and learning outcomes have increased. Teacher activity increased, in the first cycle of the first meeting the average percentage of teacher activity was 85.00% (good) increased to 90.00% (excellent) at the second meeting and increased again in cycle II fourth and fifth meeting to 100, 00% (excellent). Student activity increased, in cycle I first meeting average percentage of student activity 70.00% (good) increased to 80.00% (good) at the second meeting and increased again in cycle II fourth meeting to 85.00% (good ) and the fifth meeting becomes 90.00% (excellent). The learning outcome increased from the basic score of 64.00% (less) to 74.67% (enough) in cycle I and increased again to 81.50% (good) in cycle II. Students classical completeness in the first cycle of 76.67% (complete) increased to 90.00% (complete) in cycle II. It can be concluded that the application of direct learning can improve learning outcomes grade science students VB SD Negeri 004 Bagan Timur.Keywords: Direct Learning, Learning outcomes
Efektifitas Terapi Kombinasi Gazoprevir Dan Elbasvir Pada Koinsidensi Infeksi Hepatitis C Dengan Gagal Ginjal Kronik Yang Menjalani Hemodialisis Abubakar, Azzaki; Gunawan, Andrie; Sari, Julia
Journal of Medical Science Vol 5 No 2 (2024): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v5i2.147

Abstract

Infeksi virus hepatitis C kronis (HCV) adalah penyebab utama morbiditas dan mortalitas terkait hati di seluruh dunia dan merupakan predisposisi fibrosis hati dan komplikasi hati stadium akhir. Tidak berbeda dengan hepatitis C, PGK juga masih menjadi masalah kesehatan dan beban ekonomi yang tinggi di dunia. Pada tahun 2017 prevalensi hepatitis C pada pasien hemodialisis di 3 unit HD rumah sakit di Jakarta sebesar 38%. Pasien PGK yang terinfeksi VHC memiliki risiko penurunan fungsi ginjal yang lebih cepat dibandingkan yang tidak terinfeksi VHC. Ditemukan juga adanya peningkatan mortalitas pasien PGK yang terinfeksi hepatitis C. RSUDZA merupakan salah satu dari Rumah Sakit pemerintah yang dilibatkan dalam program pengobatan infeksi hepatitis C pada pasien PGK. Penelitian ini bertujuan untuk mengetahui bagaimana insidensi pasien PGK yang terinfeksi hepatitis C yang menjalani hemodalisa dan mengetahui bagaimana identifikasi data demografi pasien dan nilai laboratorium terhadap keberhasilan pengobatan sesuai dengan prosedur tetap pada pasien infeksi hepatitis C. Metode yang digunakan dalam penelitian ini adalah desain cross sectional. Pasien gagal ginjal kronik yang menjalani hemodialisis dengan hasil anti HCV positif dilakukan pendataan umur, jenis kelamin, lamanya HD, riwayat transfusi, riwayat keluarga dan ada tidaknya penyakit komorbid seperti diabetes mellitus dan hipertensi. Lalu dilakukan pemeriksaan laboratorium berupa AST, Platelet, Ureum, Kreatinin, Anti HCV dan HCV RNA. Pasien juga dilakukan penilaian terhadap derajat fibrosis yaitu penilaian skor APRI. Pasien diberikan terapi dengan menggunakan Grazoprevir/elbasvir selama 12 minggu, lalu dinilai ulang keberhasilan terapi dengan terdeteksi atau tidak terdeteksinya Anti HCV dan HCV RNA. Pasien dilakukan evaluasi laboratorium pada minggu ke 4, ke-8 dan ke -12. Didapatkan 15 dari 294 pasien PGK yang menjalani hemodialisis (5,11 %) menunjukkan hasil anti HCV positif dengan usia penderita terbanyak diatas 45 tahun (39.47%) serta didominasi jenis kelamin perempuan (60%). Dari 38 pasien anti HCV positif didapatkan 12 pasien (80 %) dengan HCV RNA terdeteksi. Kelompok yang diterapi terbagi menjadi 2 kelompok yaitu kelompok yang tuntas menjalani pengobatan selama 12 minggu sebanyak 4 pasien (33,33%). Pasien tuntas menjalani pengobatan selama 3 bulan pengobatan dengan keseluruhan hasil HCV RNA tidak terdeteksi lagi, terdapat perbaikan nilai SGOT dan penurunan skor APRI yang menunjukkan perbaikan fibrosis hati. Pasien hepatitis C yang patuh menjalani pengobatan dan tatalaksana hepatitis C mendapatkan hasil yang baik dan terjadi perbaikan terhadap fibrosis hati serta parameter laboratorium. Kepatuhan terhadap pengobatan dipengaruhi oleh berbagai faktor baik dari pasien sendiri dan keluarga, ketersediaan obat, akses ke pusat layanan kesehatan dan edukasi yang optimal.
Keberhasilan Tatalaksana Infeksi Virus Hepatitis C di Rumah Sakit Umum Daerah dr. Zainoel Abidin Banda Aceh dr. Azzaki Abubakar, Sp.PD-KGEH; dr. Andrie Gunawan, SpPD; Julia Sari
Journal of Medical Science Vol 3 No 2 (2022): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v3i2.87

Abstract

Hepatitis C is a world health problem with a high mortality rate. The Indonesian Ministry of Health has been controlling hepatitis C infection since 2017 using Direct Acting Antiviral (DAA) drugs which have lower side effects and a higher cure rate. This study aims to determine incidence, patient demographic data, and liver fibrosis scores on the successful treatment of hepatitis C infection at RSUD dr. Zainoel Abidin Hospital. Inclusion criteria in this retrospective cohort design was patients with positive anti hepatitis C virus (Anti-HCV). Treatment was carried out when the viral load was detected by giving Sofosbuvir 400 mg per day and Daclatasvir 60 mg per day for 12 weeks, then patient returns to be examined to assess the successful therapy. Thirty eight out of 5002 patients (0.76%) showed positive Anti-HCV, most patients aged over 60 years (39.47%), was dominated by male (55.26%), and most of them are located in Banda Aceh (47 ,36 %). Thirty out of 38 positive anti-HCV patients (78.95%) had HCV RNA, but 15 patients (50%) were not eligible for treatment. Seven out of 15 patients (46.7%) completed DAA treatment. All HCV RNA were undetectable, improved AST values ​​and decreased aspartate aminotransferase-platelet ratio index (APRI) scores which showed improvement in liver fibrosis, after completing therapy. Hepatitis C patients who adhere to treatment and management of hepatitis C will get good results marked by improvement in liver fibrosis and undetectable HCV RNA.
Hubungan Antara Depresi, Anemia Defisiensi Besi dan Status Nutrisi Terhadap Gangguan Tidur pada Pasien Penyakit Ginjal Kronik yang Menjalani Hemodialisis: The Relationship between Depression, Iron Deficiency Anemia and Nutritional Status of Sleep Disorders in Chronic Kidney Disease Patients Who Undergoing Hemodialysis Vera abdullah; Salwani, Desi; Erlita, Diana; Sari, Julia
Journal of Medical Science Vol 6 No 2 (2025): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v6i2.229

Abstract

Penyakit ginjal kronis (PGK) memengaruhi lebih dari 10% populasi dunia, dengan jumlah lebih dari 800 juta orang. Gangguan tidur sangat sering terjadi pada pasien dialisis, dengan prevalensi keluhan tidur tercatat antara 30–80% kasus. Namun, penelitian mengenai prevalensi kualitas tidur pada pasien hemodialisis masih terbatas. RSUDZA memiliki pusat hemodialisis, namun belum pernah dilakukan penelitian terkait gangguan tidur pada pasien hemodialisis. Penelitian ini bertujuan untuk mengetahui gambaran depresi, anemia defisiensi besi, dan status nutrisi pada pasien Penyakit ginjal kronis (PGK)  yang menjalani hemodialisis serta hubungannya dengan kualitas tidur. Desain penelitian yang digunakan adalah analitik dengan pendekatan potong lintang. Data karakteristik pasien yang dikumpulkan meliputi nama, umur, jenis kelamin, tinggi badan, berat badan dan lama dialisis. Kualitas tidur dinilai menggunakan kuesioner dan wawancara dengan menggunakan Pittsburgh Sleep Quality Index (PSQI). Skrining depresi dilakukan menggunakan Hospital Anxiety and Depression Scale (HADS) dan penilaian derajat keparahan depresi menggunakan Beck Depression Inventory (BDI). Status nutrisi dinilai dengan pemeriksaan Indeks Massa Tubuh. Hasil penelitian menunjukkan bahwa mayoritas pasien hemodialisis berjenis kelamin laki-laki (57%), berusia di atas 45 tahun, dan sebagian besar sudah menjalani hemodialisis selama 2-5 tahun serta memiliki status gizi baik. Sebagian besar pasien memiliki status psikologis yang baik. Semua pasien hemodialisis mengalami anemia, namun hanya sebagian kecil yang mengalami anemia defisiensi besi (31%). Sebanyak 64% pasien yang menjalani hemodialisis mengalami gangguan tidur. Gangguan tidur terutama terjadi pada pasien yang tidak mengalami depresi, tanpa anemia defisiensi besi dan memiliki berat badan normal. Temuan ini menunjukkan bahwa gangguan tidur pada pasien hemodialisis tidak hanya dipengaruhi oleh faktor psikologis dan status nutrisi, tetapi juga kemungkinan terkait dengan berbagai faktor lain seperti perubahan metabolisme akibat uremia, gangguan elektrolit, nyeri, pruritus, dan jadwal dialisis.
Co-Authors Anggoro Budi Hartopo Azzaki Abubakar, Azzaki Budi Yuli Setianto Desi Salwani, Desi dr. Andrie Gunawan, SpPD dr. Azzaki Abubakar, Sp.PD-KGEH Erlita, Diana Gunawan, Andrie Mahmud Alpusari Putrika Prastuti Ra Gharini Putrika Prastuti Ra Gharini Vera abdullah