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All Journal Pharmacology and Clinical Pharmacy Research JCPS (Journal of Current Pharmaceutical Sciences) Journal of Holistics and Health Sciences (JHHS) Indonesian Journal of Pharmacy and Natural Product Indonesian Journal of Community Empowerment (IJCE) Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Science and Community Pharmacy Journal
Wahyudi, Andrey
Universitas Ngudi Waluyo
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Rationality Analysis of Antibiotics for Community-Acquired Pneumonia in Adult Inpatients at X Hospital Sukoharjo Rahardjoputro, Rolando; Amrullah, Adhi W.; Rizky, Wahyu; Ernawati, Ernawati; Wahyudi, Andrey; Widyaningrum, Nova R.
Pharmacology and Clinical Pharmacy Research Vol 10, No 1 (2025)
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/pcpr.v10i1.53198

Abstract

Community-acquired pneumonia in adult patients contributes to high morbidity and mortality rates. The rationality of antibiotics for community-acquired pneumonia pharmacotherapy can determine the result of patient clinical outcomes. The aim of this study was to determine antibiotics rationality for community-acquired pneumonia in adult inpatients at X Hospital Sukoharjo and relationship between antibiotics rationality and its clinical outcomes.This study was analytical cohort design with retrospective data in the form of patient medical records for the period 2022. Sampling method was carried out using total sampling with inclusion criteria being patients aged ≥ 18 years, male or female, diagnosed with community-acquired pneumonia and receiving antibiotic therapy. The total samples was 102 who met the inclusion criteria which 52% was female gender and predominantly aged ≥ 65. The rationality analysis using Gyssens method showed that 29.51% of antibiotics were given rationally with the highest number of irrationalities due to another more effective antibiotics (category IVA) at 54.90%. There was no significant relationship between antibiotic rationality and its clinical outcomes.
Co-Authors Amrullah, Adhi W. Arifah, Ningrum Cahyani, Dewa Ayu Yuliastri Dyah Aryani Perwitasari Ernawati Ernawati Ika Nilawati Juliana, Resi Kusfindyasmoro, Catur Estiawan Ningrum Arifah Nintisari, Jenica Nurhayati, Ratri Pertiwi, Sulih Pratiwi, Neli Diah Putri, Assysifa Septyani Putri, Eka Firdhausia Rahardjoputro, Rolando Rizky, Wahyu safna Tri Minarsih Widyaningrum, Nova R.