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All Journal Jurnal Kesehatan Prima Jurnal Analis Medika Biosains (JAMBS) Jurnal Penelitian dan Kajian Ilmiah Kesehatan Politeknik Medica Farma Husada Mataram Journal of Indonesia Laboratory Students (JILTS)
Erna Kristinawati
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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HUBUNGAN KADAR NITRIT OKSIDA (NO) DALAM DARAH TERHADAP RESIKO KEJADIAN DIABETES MELLITUS TIPE 2 DENGAN HIPERTENSI DI RSUP NTB I Gusti Ayu Nyoman Danuyanti; Erna Kristinawati; Ersandhi Resnhaleksmana
Jurnal Kesehatan Prima Vol 8, No 1 (2014): Jurnal Kesehatan Prima
Publisher : poltekkes kemenkes mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.272 KB) | DOI: 10.32807/jkp.v8i1.42

Abstract

Abstract: Diabetes Mellitus (DM) is a group of metabolic diseases with characteristic hyperglycemia that occurs due to abnormalities in insulin secretion, insulin action or both. Pathophysiology of type 2 diabetes mellitus are very complex with involving a variety of factors, including nutrition, obesity, sedentary lifestyle, and lack of physical activity, and genetik. The prolonged  of condition hyperglycemia causes endothelial cell dysfunction resulting in decreased production of various compounds that are antithrombotic and vasodilating include nitric oxide ( NO). The purpose of this study was to determine the relationship between levels of nitric oxide (NO) in the blood against the risk of incident type 2 diabetes mellitus with hypertension at the RSUP NTB. This study uses a case-control design, with a sample size of 30 people with type 2 diabetes with hypertension as the case group and 30 patients without hypertension, diabetes mellitus type as the control group. The total sample is 60 people. Dependent variable in this study is the levels of NO in the blood while the independent variables of type 2 DM patients with hypertension. Determination of levels of nitric oxide (NO) in the blood using spectrophotometric methods. Correlation test is used to determine the relationship between levels of nitric oxide (NO) in blood with the blood pressure while Chi-square test used to determine the relationship of NO levels on the risk of incident type 2 diabetes with hypertension. The results showed average mean levels of NO in patients with type 2 diabetes with hypertension was lower than 0.54 μM with type 2 DM patients without hypertension is 1.32 μM. The results of correlation test levels of NO in the blood and blood pressure showed p-value = 0.000 (<α 0.05) and there is a strong relationship with a correlation coefficient value of 0.749 for systolic blood pressure and 0.694 for diastolic. Analysis of the relationship of NO levels in the blood against the risk of incident type 2 diabetes with hypertension show the value of p = 0.000. The overall from the can be concluded There is a relationship between the amount of nitric oxide (NO) in the blood against the risk of incident type 2 diabetes mellitus with hypertension in the RSUP NTB.
Analisis Jumlah dan Jenis Bakteri Coccus Gram Positif pada Sisa Sampel Darah di Spuit Sofiyan Dwi Arfi; Erna Kristinawati; Ari Khusuma
Jurnal Analis Medika Biosains (JAMBS) Vol 9, No 2 (2022): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v9i2.270

Abstract

.Background: One of the problems in the field of health services that can increase the mortality rate is nosocomial infection. Waste containing pathogenic bacteria can serve as a medium for the spread of disease for health facility workers, sufferers and the public. One of the medical devices that have a high risk factor as an intermediary for infection is a syringe. Bacterial contamination of the syringe after use cannot be ignored. Therefore, further research is needed on waste in health facilities to determine infectious diseases caused by residual blood samples in the syringe. Research Objectives: To determine the presence of gram-positive coccus bacteria in the remaining blood sample in the syringe. Methods: This study used a descriptive observational method with a cross sectional approach to time. The sample size in this study was 14 samples with a sampling technique that is total sampling. Results: It was found that Staphylococcus aureus and Staphylococcus cohnii were found each of the 14 samples. Conclusion: There are gram-positive coccus bacteria, namely Staphylococcus cohnii and Staphylococcus aureus. 
EKSTRAK BUNGA CENGKEH SEBAGAI INSEKTISIDA TERHADAP MORTALITAS NYAMUK AEDES AEGYPTI METODE SEMPROT DRS IWAYAN GETAS,M.Sc Ariwidiani; Ariwidhiani; Erna Kristinawati
Jurnal Penelitian dan Kajian Ilmiah Kesehatan Politeknik Medica Farma Husada Mataram Vol. 7 No. 2 (2021): JURNAL PENELITIAN DAN KAJIAN ILMIAH KESEHATAN POLITEKNIK MEDICA FARMA HUSADA MA
Publisher : Politeknik Medica Farma Husada Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (760.853 KB) | DOI: 10.33651/jpkik.v7i2.232

Abstract

Peningkatan kasus DBD di Indonesia pada tahun 2016 sebanyak 204.171 kasus dengan jumlah kematian sebanyak 1.598 orang. Berdasarkan data profil kesehatan Indonesia, telah terjadi peningkatan kasus DBD di setiap tahunnya. Peningkatan angka kesakitan DBD juga terjadi di NTB pada tahun 2016 yaitu sebesar 52,80 per 100.000 penduduk. Pemanfaatan bunga cengkeh sebagai bahan insektisida alami dapat menjadi alternatif yang lebih ramah lingkungan sehingga dapat menekan dampak negatif dari penggunaan insektisida kimia. Tujuan dalam penelitian ini adalah untuk menganalisis potensi ekstrak bunga cengkeh (Syzygium aromaticum) sebagai insektisida terhadap nyamuk Aedes aegypti dengan metode semprot. Penelitian ini merupakan penelitian eksperimental dengan post-test only controlled group design. Perlakuan dilakukan dalam 5 konsentrasi yaitu 5%, 10%, 15%, 20% dan 25%. Data yang diperoleh dianalisis secara statistic menggunakan uji Chi Square dan analisis probit. Berdasarkan hasil analisis, ekstrak bunga cengkeh (Syzygium aromaticum) berpotensi sebagai insektisida terhadap nyamuk Aedes aegypti dengan nilai signifikan 0.000 (p < 0.05) dengan konsentrasi LC50 diperoleh sebesar 3,434% dan LC90 sebesar 22,070%.
Description of SGPT Levels in Construction Workers Who Have an Active Smoking Habit Eva Sapna; Nurul Inayati; Yudha Anggit Jiwantoro; Erna Kristinawati
Jurnal Analis Medika Biosains (JAMBS) Vol 11, No 1 (2024): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v11i1.349

Abstract

Physical activity is body movement that requires skeletal muscles and can cause energy expenditure. Physical activity is divided into three, namely light, moderate and heavy physical activity. Construction workers who carry out heavy physical activity for 7 to 8 hours every day can lose a lot of energy and fluids as well as important micronutrients, one of which is iron. Apart from carrying out heavy physical activities, construction workers also have an active smoking habit, which means they are considered active smokers if they smoke more than 20 cigarettes every day. Smoking is something that can cause health problems and smoking has become the biggest cause of death in the world. Cigarette raw materials such as tar, nicotine and carbon monoxide are the main toxicants that can trigger the formation of free radicals. The Research objective is to determine the description of SGPT levels in construction workers who have an active smoking habit. The methods of this research design is descriptive observational research where this research was carried out using the enzymatic kinetic method a total of 28 samples based on calculations using the Slovin formula. The results of the research is examining SGPT levels in construction workers from 28 samples showed an increase in active smokers 11-15 years, namely 3 samples and active smokers 16-20 years, namely 2 samples, there was an increase or were outside the normal value, which is where the normal value of SGPT levels in men -men, namely 42 U/L. The conclusion of this research is showed that 5 of the 28 samples had increased SGPT levels with levels of 63 U/L, 58 U/L, 52 U/L and 49 U/L in 2 samples.
Hubungan Kadar CRP dan Tekanan Darah Pada Wanita Obesitas di Wilayah Kerja Puskesmas Bagu Adila Ika Rahmayati; Ari Khusuma; Erna Kristinawati; Pancawati Ariami
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 2 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v3i2.151

Abstract

Background: Body mass index (BMI) ≥30 kg/m² is defined as obesity II. Obese sufferers have a risk of increased blood pressure or hypertension, which is also associated with low-level inflammatory conditions. CRP is a test used to detect inflammatory processes, which can affect blood vessel damage. Research Objective: To determine the relationship between CRP levels and blood pressure in obese women in the Bagu Health Center Working Area. Research Methods: This research design is an analytical observational study with a cross sectional approach. By examining CRP levels using the latex agglutination method. Next, data analysis was carried out using bivariate tests. Results: The results of measurements of normal systolic blood pressure, prehypertension, hypertension I, hypertension 2, and hypertensive crisis were found respectively, namely 2 (9%), 6 (29%), 5 (24%), 7 (33%), 1 (5 %) and normal diastolic blood pressure-prehypertension, hypertension I, hypertension II respectively 7 (33%), 9 (43%), 5 (24%). With CRP levels of 5 (24%) respondents 6 mg/L and 16 (76%) respondents CRP negative. The results of data analysis show a relationship between CRP levels and systolic and diastolic blood pressure, namely <0.05 P-Value >α (α=0.05), which means there is no relationship between CRP levels and blood pressure in obese women in the Bagu Community Health Center working area. Conclusion: There was no relationship between CRP levels and blood pressure in obese women in the Bagu Community Health Center working area.
Uji Efektivitas Kombinasi Ekstrak Bawang Putih (Allium sativum) dan Ekstrak Daun Srikaya (Annona squamosa L) sebagai Larvasida Aedes sp Penyebab Demam Berdarah Dengue Haryanti, Alya; Erna Kristinawati; Iswari Pauzi; Nurul Inayati
Journal of Indonesia Laboratory Students (JILTS) Vol. 4 No. 1 (2025): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v4i1.194

Abstract

Latar Belakang: Demam Berdarah Dengue (DBD) merupakan penyakit yang disebabkan oleh nyamuk Aedes sp. melalui gigitannya. Pengendalian DBD dalam mengatasi perkembangan vektor dilakukan dengan penggunaan larvasida sebagai insektisida yang dapat menghambat perkembangbiakan larva, tetapi penggunaan larvasida kimia memiliki efek samping yang dapat merugikan lingkungan, sehingga dibuat larvasida alternative dari bahan alami seperti bawang putih (Allium sativum) dan daun srikaya (Annona squamosa L.) keduanya memiliki kandungan yang terbukti sebagai larvasida.Tujuan Penelitian: Mengetahui efektivitas kombinasi ekstrak bawang putih dan ekstrak daun srikaya sebagai larvasida larva nyamuk Aedes sp.Metode Penelitian: Jenis penelitian ini quasi eskperiment dengan desain penelitian Post Test Only With Group Desaign. Jumlah unit percobaan 24 unit (4 perlakuan dengan 6 pengulangan) yaitu dengan konsentrasi perbandingan 40%:60%, 50%:50%, 60%:40% dan kontrol negative, serta dilakukan uji statistik One Way Anova.Hasil Penelitian: Rerata kematian larva nyamuk Aedes sp. pada konsentrasi perbandingan 40%:60% sebesar 76% kematian, konsentrasi 50%:50% sebesar 80% kematian, dan pada konsentrasi 60%:40% sebesar 88% kematian larva.Kesimpulan: Ada efektivitas kombinasi ekstrak bawang putih dan daun srikaya terhadap kematian larva Aedes sp. ditandai dengan diperoleh nilai p = 0,000 < 0,05. Kata Kunci: Larvasida, Larva Aedes sp. Bawang Putih, Daun Srikaya
Analisis Tingkat Infeksi Soil Transmitted Helmints (STH) dengan Kadar Haemoglobin pada Ibu Hamil di Wilayah Kerja Puskesmas Ampenan Anwariah, Zuhairatun; Nurul Inayati; Erna Kristinawati; Rohmi
Journal of Indonesia Laboratory Students (JILTS) Vol. 4 No. 1 (2025): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v4i1.122

Abstract

Latar Belakang: STH (Soil Transmitted Helminths) merupakan Nematoda usus membutuhkan tanah untuk proses pematangan sel telur dalam siklus hidupnya yang dapat menjadikan stadium non infektif menjadi stadium infektif. Sedangkan Hemoglobin merupakan molekul yang terdiri dari kandungan heme atau zat besi dan rantai polipeptida globin yaitu alfa, beta, gama, dan delta. Tujuan Penelitian: Mengetahui tingkat infeksi STH (Soil Transmitted Helminths) dengan kadar haemoglobin pada ibu hamil di wilayah kerja Puskesmas Ampenan. Metodelogi Penelitian: Rancangan pada penelitian ini adalah observasional analitik dengan metode cross sectional. Teknik pengambilan sampel yang digunakan adalah teknik non probability sampling yaitu accidental sampling dan uji statistik yang di gunakan adalah uji Sperman Rank, dengan jumlah sampel sebanyak 24 ibu hamil dengan Hb ≤ 11gr%. Hasil Penelitian: Berdasarkan hasil pemeriksaaan telur cacing Soil Transmitted Helmint pada ibu hamil dengan kadar Hb ≤11gr% di dapati 2 responden yang menunjukan hasil positif terinfeksi STH , sedangkan 22 responden menunjukan hasil negative dikarenakan tidak ditemukan telur cacing STH. Adapun jenis telur cacing yang ditemukan adalah Trichuris trichura. Rata-rata kadar haemoglobin ibu hamil yang di periksa feses nya adalah 10,7 gr%. Jumlah telur cacing Trichuris trichiura yang terhitung pada hasil positif dengan metode pemeriksaan Kato Katz adalah 40 per gr feses yang masuk dalam kategori tingkat infeksi rendah. Kesimpulan: Secara statistik tidak tedapat hubungan yang signifikan antara tingkat infeksi STH (Soil Transmitted Hemlinths) terhadap kejadian anemia pada ibu hamil.
Co-Authors Adila Ika Rahmayati Anwariah, Zuhairatun Ari Khusuma Ariwidhiani DRS IWAYAN GETAS,M.Sc Ariwidiani Ersandhi Resnhaleksmana Eva Sapna Haryanti, Alya I Gusti Ayu Nyoman Danuyanti Iswari Pauzi Nurul Inayati Pancawati Ariami Rohmi Sofiyan Dwi Arfi Yudha Anggit Jiwantoro