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Rohmi
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

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Analisis Jenis dan Penyebab Anemia Berdasarkan Kadar Hemoglobin dan Nilai MCV (Mean Corpuscular Volume) Pada Penderita Tuberkulosis Paru Baru Di Puskesmas Dasan Tapen Nova Ramdhani, Iid Nirmala; Rohmi; Lalu Srigede; Agrijanti
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 2 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v3i2.106

Abstract

Background: Tuberculosis is an infectious lung disease caused by Mycobacterium Tuberculosis which can cause several complications, including a decrease in hemoglobin levels, abnormal erythrocyte index values that can cause anemia. Examination of hemoglobin levels and MCV values to determine the type of anemia in tuberculosis patients. There are several types of anemia in tuberculosis patients and causes, one of which is microcytic anemia caused by a decrease in iron. Research Objective: Determine hemoglobin levels and erythrocyte index in patients with new pulmonary tuberculosis at Dasan Tapen Health Center Research Method: This study is observational analytic with Cross Sectional approach, the number of samples is 24 samples using the lomeslow formula with hemoglobin levels and MCV values. The collected data is then analyzed using descriptive tests. Results of the study: From 24 samples of tuberculosis patients as many as 5 people (21%) with a very mild degree of anemia, 16 (67%) people with a mild degree of anemia and 3 people (12%) with a moderate degree of anemia. A total of 18 people (75%) with microcytic type anemia and 6 (25%) people with normocytic type anemia. Conclusion: From 24 samples as many as 18 people (75%) with MCV values of <80 which indicates tuberculosis patients have microcytic anemia.
Korelasi Kadar Hemoglobin dan Albumin Pada Penderita Nefropati Diabetik Pramoswari, Dining; Lale Budi Kusuma Dewi; Siti Zaetun; Rohmi
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 2 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v3i2.148

Abstract

Latar Belakang: Tingginya kadar glukosa dalam darah akan membuat struktur ginjal berubah sehingga fungsinya terganggu. Kerusakan pada ginjal dapat menyebabkan protein (albumin) dapat melewati glomerulus sehingga dapat ditemukan dalam urin yang disebut dengan albuminuria yang menyebabkan penyakit Nefropati Diabetik. Adanya gangguan pada ginjal akan mempengaruhi Laju Filtrasi Glomeroulus (LFG) yang menunjukkan semakin sedikitnya nefron yang berfungsi sehingga menyebabkan terganggunya produksi eritropoietin pada ginjal untuk memproduksi sel darah merah, maka hemoglobin terjadi penurunan. Tujuan Penelitian: Menganalisis adanya Korelasi Kadar Hemoglobin dan Albumin Pada Penderita Nefropati Diabetik Metode Penelitian: Penelitian ini menggunakan metode observasional analitik dengan pendekatan cross sectional. Penderita ND akan dilakukan pemeriksaan kadar hemoglobin dan albumin, selanjutnya data yang diperoleh kemudian diuji korelasi person. Hasil Penelitian: Didapatkan 15 total sampel keseluruhan dengan rerata kadar albumin serum 2,4 g/dl dan rerata kadar hemoglobin 9,2 g/dl. Kesimpulan: Adanya Korelasi antara kadar hemoglobin dan albumin pada penderita Nefropati Diabetik sebesar 0,787 dengan nilai probabilitas (p) 0,00 < 0,05. Adapun tingkat kekuatan korelasi antara kadar Hemoglobin dan Albumin pada penderita nefropati diabetik adalah Kuat.
Perbedaan Jumlah Limfosit dan Monosit serta Morfologi Eritrosit pada Perokok Tembakau dan Elektrik sebagai Faktor Risiko Aterosklerosis pada Remaja Laila Nisa, Isra; Rohmi; Khusuma, Ari; Zaetun, Siti
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 1 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v3i1.60

Abstract

Background : Smoking from adolescence can increase the risk of atherosclerosis because there is a buildup of fibrolipids and other substances in the blood that can cause plaque. Meanwhile, research results show that e-cigarettes are no less dangerous than tobacco cigarettes. Namely, the number of lymphocytes in e-smokers is 54% and tobacco smokers are 39% (Mega, 2020). The novelty of this research is to look at differences in erythrocyte count and morphology in adolescents at risk of atherosclerosis. Research Objectives : To determine the differences in the number of lymphocytes and monocytes and the morphology of erythrocytes in tobacco and electronic smokers as risk factors for atherosclerosis in adolescents. Research Methods : This research is an analytical observational study with a cross sectional research design and uses the lameshow formula to determine the sample size so that a sample size of 30 samples can be obtained. Data were tested using the Independent T-test and Mann Whitney-U test. The results of the study : The average percentage of lymphocytes and monocytes in tobacco and electronic smoker is 37% & 27% lymphocytes and 7% & 6% monocytes. From 15 samples of tobacco smokers the results were normal and from 15 samples of e-smokers there was 1 lymphocyte result below normal. Also, the abnormal cells found include anulocytes, tear drops, burr cells, ovalocytes and stomatocytes. Conclusion : There are differences in the number of lymphocytes and monocytes as well as erythrocyte morphology in tobacco and electronic smokers as risk factors for atherosclerosis in adolescents with the probability value for lymphocytes being 0.01<0.05 and monocytes 0.04<0.05.
Korelasi antara Titer Antigen H dengan Kadar SGPT pada Pasien Demam Tifoid Helenia Ananda Feriska Felanis; Ida Bagus Rai Wiadnya; Thomas Tandi Manu; Rohmi; Pauzi, Iswari
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 1 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v3i1.79

Abstract

Latar Belakang: Demam tifoid merupakan penyakit demam akut yang disebabkan oleh infeksi bakteri Salmonella enterica serotipe typhi atau lebih dikenal dengan nama Salmonella Typhi. Berdasarkan hasil penelitian Marselina dkk 2022, mengungkapkan bahwa bakteri Salmonella typhi masuk kedalam organ hati dan menginfeksi organ tersebut sehingga terjadi peningkatan pada kadar SGPT. Tujuan Penelitian: Mengetahui korelasi antara titer antigen H dengan kadar SGPT pada pasien demam tifoid. Metode Peneltian: Obeservasional Analitik dengan pendekatan cross sectional. Teknik Pengambilan sampel yang digunakan dalam penelitian ini adalah Non Random Purposive Sampling. Jumlah sampel yang digunakan sebanyak 34 sampel. Penelitian ini menggunakan uji statistik Korelasi Pearson. Hasil Penelitian: Sampel penderita demam typhoid sebanyak 34 sampel meliputi titer widal antigen H 1/80 berjumlah 16 orang dengan kadar SGPT tertinggi sebesar 42 µ/L. Pada titer widal antigen H 1/160 didapatkan sampel berjumlah 10 orang dengan kadar SGPT tertinggi sebesar 34 µ/L. Sedangkan titer widal antigen H 1/320 didapatkan sampel berjumlah 8 orang dengan kadar SGPT tertinggi sebesar 34 µ/L. Hasil uji normalitas terdistribusi normal masing-masing variabel memiliki nilai signifikansi > 0,05 dan hasil uji korelasi pearson diperoleh nilai signfikansi yaitu 0,7 > 0,5 artinya tidak ada koreasi. Kesimpulan: Tidak ada korelasi antara titer antigen H dengan kadar SGPT pada pasien demam tifoid Kata kunci: Titer Antigen, SGPT, Demam Tifoid
Analisis Tingkat Infeksi Soil Transmitted Helmints (STH) dengan Kadar Haemoglobin pada Ibu Hamil di Wilayah Kerja Puskesmas Ampenan Anwariah, Zuhairatun; Nurul Inayati; Erna Kristinawati; Rohmi
Journal of Indonesia Laboratory Students (JILTS) Vol. 4 No. 1 (2025): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v4i1.122

Abstract

Latar Belakang: STH (Soil Transmitted Helminths) merupakan Nematoda usus membutuhkan tanah untuk proses pematangan sel telur dalam siklus hidupnya yang dapat menjadikan stadium non infektif menjadi stadium infektif. Sedangkan Hemoglobin merupakan molekul yang terdiri dari kandungan heme atau zat besi dan rantai polipeptida globin yaitu alfa, beta, gama, dan delta. Tujuan Penelitian: Mengetahui tingkat infeksi STH (Soil Transmitted Helminths) dengan kadar haemoglobin pada ibu hamil di wilayah kerja Puskesmas Ampenan. Metodelogi Penelitian: Rancangan pada penelitian ini adalah observasional analitik dengan metode cross sectional. Teknik pengambilan sampel yang digunakan adalah teknik non probability sampling yaitu accidental sampling dan uji statistik yang di gunakan adalah uji Sperman Rank, dengan jumlah sampel sebanyak 24 ibu hamil dengan Hb ≤ 11gr%. Hasil Penelitian: Berdasarkan hasil pemeriksaaan telur cacing Soil Transmitted Helmint pada ibu hamil dengan kadar Hb ≤11gr% di dapati 2 responden yang menunjukan hasil positif terinfeksi STH , sedangkan 22 responden menunjukan hasil negative dikarenakan tidak ditemukan telur cacing STH. Adapun jenis telur cacing yang ditemukan adalah Trichuris trichura. Rata-rata kadar haemoglobin ibu hamil yang di periksa feses nya adalah 10,7 gr%. Jumlah telur cacing Trichuris trichiura yang terhitung pada hasil positif dengan metode pemeriksaan Kato Katz adalah 40 per gr feses yang masuk dalam kategori tingkat infeksi rendah. Kesimpulan: Secara statistik tidak tedapat hubungan yang signifikan antara tingkat infeksi STH (Soil Transmitted Hemlinths) terhadap kejadian anemia pada ibu hamil.
Uji Sensitivitas dan Spesitifitas Immuno Chromatography Test -Tuberculosis (ICT - TB) pada Penderita Tuberkulosis Paru di Kabupaten Bima-NTB Fitri; Rohmi; Ariami, Pancawati; Kusuma Dewi, Lale Budi
Journal of Indonesia Laboratory Students (JILTS) Vol. 4 No. 1 (2025): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v4i1.213

Abstract

Background: The problem of Tuberculosis (TB) is a healt problem thathas long been faced by various countries in the world, includingIndonesia. Tuberculosis is an infectious disease caused by infectionwith the germ Mycobacterium tuberculosis. Tuberculosis disease mostlyaffects the lung parenchyma (pulmonary TB). ICT-TB is a serologicaltest that is fast, simple and easy bto operate. The limited of number ofGenexpert MTB in Bima regency is an obstacle in establishing an earlytuberculosis. Objective: To determinan the sensitivity and specificity of the immunochromatography test-tuberculosis (ICT-TB) method in TB patients. Method: This study is an analytical abservational study, with apurposive sampling approach, namely research samples taken fromserum specimens for the ICT-TB method and sputum for GenexpertMTB as standart. The sensitivity and specificity for ICT-TB werecalculated manually using the Mc nemar formula in the 2 x 2 diagnostictest table. Results: The ICT- TB result showed 4 positive IgG respondents and 41negative respondents, while the Genexpert MTB result showed 6 MTBDetected and 39 MTB Not Detected. The ICT-TB sensitivity test resultfor TCM were 50% and specificity 97,44%. Conclusion: ICT-TB method has excellent specificity value. However ,the ICT-TB method examination still has shortcomings that are notfound in the Genexpert MTB method.Recommendation: Further research needs to be carried out usingsamples of tuberculosis positive patients who have not receivedtreatment.
Co-Authors Agrijanti Anwariah, Zuhairatun Dewi, Lale Budi Kusuma Erna Kristinawati Fitri Helenia Ananda Feriska Felanis Khusuma, Ari Laila Nisa, Isra Lalu Srigede Nova Ramdhani, Iid Nirmala Nurul Inayati Pancawati Ariami Pauzi, Iswari Pramoswari, Dining Siti Zaetun Siti Zaetun, Siti Thomas Tandi Manu Wiadnya, Ida Bagus Rai