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All Journal Nexus Kedokteran Klinik Magna Neurologica
Martha Oktavia Dewi Savitri
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Hubungan Jenis Kelamin dengan Kualitas Hidup Terkait Kesehatan Pasien Pasca Stroke Iskemik di RSUD Dr. Moewardi Savitri, Martha Oktavia Dewi; Hartanto, Oemar Sri; Murti, Bhisma
Nexus Kedokteran Klinik Vol 3, No 3 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Abstract

Background: Stroke has remained the top major killers during this last decade, actually as second leading cause of death in the world. Men suffers more stroke than women, yet the severity is worse in women.  Based on some literatures, the outcome after stroke is estimated by sex, female patient has poor recovery with greater chance of depression and tends to have more disabilities, impairments and dependencies in functional activities, which these will deteriorate patient’s health related quality of life (HRQOL).  This study aims to investigate  whether there is any correlation between sex and health related quality of life of post ischemic stroke patients. Methods: This study was performed using analytic observational method with cross sectional approach. Subjects were post ischemic stroke patients at Public Hospital Dr. Moewardi. Forty five samples were taken by using fixed exposure sampling method. Instruments used in this study were Health Related Quality of Life (HR-QOL) SF-36 and Family Support Instrument. Statistic test used in this study was multiple linear regression analysis. Results: Twenty three samples (51.1 %) were men. The average age of patients is around 59 years, with an average score of HR-QOL= 353.35. It has been found that there is significant negative correlation between female patients and HR-QOL for b= -69.35, p=0.000 (p<0.05). It also has been found that the confounding factor of age is negatively and significantly correlated to the HR-QOL for b= -3.84, p= 0.000 (p<0.05) and the confounding factor of family support has significantly positive correlation to HR-QOL for b= 10.33, p=0.000 (p<0.05). Adjusted R2= 0.95 showing the suitability of the model by 95% in the population. Conclusion: Female patients averagely have lower HR-QOL score as much as 69.35 than male patients. One year increment in age will decrease HR-QOL score as much as 3.84  points. And each 1-score increase in family support will enhance HR-QOL score as much as 10.33 points. Keywords: sex, age, family support, health related quality of life, post ischemic stroke patients 
Hubungan Jenis Kelamin dengan Kualitas Hidup Terkait Kesehatan Pasien Pasca Stroke Iskemik di RSUD Dr. Moewardi Martha Oktavia Dewi Savitri; Oemar Sri Hartanto; Bhisma Murti
Nexus Kedokteran Klinik Vol 3, No 3 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Abstract

Background: Stroke has remained the top major killers during this last decade, actually as second leading cause of death in the world. Men suffers more stroke than women, yet the severity is worse in women. Based on some literatures, the outcome after stroke is estimated by sex, female patient has poor recovery with greater chance of depression and tends to have more disabilities, impairments and dependencies in functional activities, which these will deteriorate patients health related quality of life (HRQOL). This study aims to investigate whether there is any correlation between sex and health related quality of life of post ischemic stroke patients. Methods: This study was performed using analytic observational method with cross sectional approach. Subjects were post ischemic stroke patients at Public Hospital Dr. Moewardi. Forty five samples were taken by using fixed exposure sampling method. Instruments used in this study were Health Related Quality of Life (HR-QOL) SF-36 and Family Support Instrument. Statistic test used in this study was multiple linear regression analysis. Results: Twenty three samples (51.1 %) were men. The average age of patients is around 59 years, with an average score of HR-QOL= 353.35. It has been found that there is significant negative correlation between female patients and HR-QOL for b= -69.35, p=0.000 (p<0.05). It also has been found that the confounding factor of age is negatively and significantly correlated to the HR-QOL for b= -3.84, p= 0.000 (p<0.05) and the confounding factor of family support has significantly positive correlation to HR-QOL for b= 10.33, p=0.000 (p<0.05). Adjusted R2= 0.95 showing the suitability of the model by 95% in the population. Conclusion: Female patients averagely have lower HR-QOL score as much as 69.35 than male patients. One year increment in age will decrease HR-QOL score as much as 3.84 points. And each 1-score increase in family support will enhance HR-QOL score as much as 10.33 points. Keywords: sex, age, family support, health related quality of life, post ischemic stroke patients
A 61-Years-Old Female with Moyamoya Syndrome: A Case Report Savitri, Martha Oktavia Dewi; Fairuzya, Azmi Farah; Subandi; Imanuddin, Iqbal; Romadhoni, Andry Nur Wahyu Putra; Hosoya, Tomohiro
Magna Neurologica Vol. 3 No. 1 (2025): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v3i1.1119

Abstract

Background: Moyamoya vasculopathy (MMV), like Moyamoya disease (MMD) and Moyamoya syndrome (MMS), is a rare chronic cerebrovascular angiopathy, especially in elderly patients. The incidence onset of MMV were unique with bimodal peak age: 5-10 years old and 25-49 years old. Case: A 61-year-old-female complaint of sudden onset left-sided hemiparesis one month before admission, headache, and forgetfulness. She had history of diabetes mellitus for 3 years. Neurological physical examination found left hemiparesis with motoric strength 4/5. Laboratory findings are unremarkable. Brain MRI with contrast showed infarcts at subcortical regions. Her cerebral DSA examination suggested diffuse multiple stenosis in the anterior circulation and total occlusion of left external and internal carotid artery. “Puff of smoke” and “champagne-bottle like neck sign” were found in DSA imaging, typical signs of MMD. She received aspirin 80 mg as her secondary prevention of another stroke event.  Discussion: MMV case at elderly onset which is similar to prior small study with mean age of 60 years old. Previous study mentioned hypertension (44%) and diabetes mellitus (16%) were found in older MMD patients. Patient was given aspirin 80mg daily. Precautions in this case include taking lifelong antiplatelet, managing diabetes mellitus, and implementing lifestyle modification. This treatment approach was directed to lower concomitant risk of ischemic stroke. Conclusion: We report a case of MMV which was considered as a rare case and a cause of stroke event. The management of this case was directed to control the coexisting condition of ischemic stroke using antiplatelet drug and risk factor management.
Recurrent Brain Abscess in 40-Years-Old Female Associated with Ventricular Septal Defect: A Case Report Fairuzya, Azmi Farah; Savitri, Martha Oktavia Dewi; Prabaningtyas, Hanindia Riani; Watanabe, Yasuhiro; Murakami, Takenobu; Tajiri, Yuki
Magna Neurologica Vol. 3 No. 1 (2025): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v3i1.1123

Abstract

Background: Ventricular septal defect (VSD) is one of the critical risk factors for brain abscess. The unsterile blood in uncontrolled cyanotic congenital heart disease cases will travel to the brain after escaping the filtration mechanism and cause brain abscess. Case: A 40-year-old female presented with a two-week course of moderate headaches, worsening severely four days before admission. Neurological manifestations included attention deficits, dysarthria, right-sided hemiparesis, and proper facial palsy. Laboratory findings indicated leukocytosis and polycythemia. Echocardiography revealed VSD. Brain MRI with contrast suggested a single abscess lesion in the left occipital lobe. A histopathological examination confirmed the diagnosis. Antibiotics were administered during hospitalization, with outpatient treatment afterward. A one-month follow-up revealed new symptoms and a subsequent surgical excision. Discussion: Brain abscess remains a challenging and life-threatening case despite advanced diagnostic techniques. Uncontrolled cyanotic heart disease might be an essential risk factor for brain abscess occurrence. Thorough diagnostic examinations must be conducted to establish the diagnosis. The optimal empirical-targeted antibiotic treatment is a cornerstone of management. After antibiotic therapy, a surgical approach must be considered in lesions with large-size or nonoptimal size reduction. It is essential to comprehensively manage brain abscesses and their etiology to reduce the recurrence rate. Conclusion: Brain abscess associated with uncontrolled cyanotic congenital heart disease requires comprehensive treatment involving antibiotics and surgery. Addressing underlying causes and cost-effective follow-ups with clinical and monthly imaging assessments are essential.
Co-Authors Bhisma Murti Fairuzya, Azmi Farah Hosoya, Tomohiro Iqbal Imanuddin Murakami, Takenobu Oemar Sri Hartanto Oemar Sri Hartanto Prabaningtyas, Hanindia Riani Romadhoni, Andry Nur Wahyu Putra Tajiri, Yuki Watanabe, Yasuhiro