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All Journal International Journal of Public Health Science (IJPHS) Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Medical Journal of Indonesia MNJ (Malang Neurology Journal) Smart Medical Journal SEMAR Neurona
Prabaningtyas, Hanindia Riani
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Humanities Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Coronavirus disease 2019 (COVID-19) related stroke incidence: a case series Prabaningtyas, Hanindia Riani; Hapsari, Maria Yosita Ayu; Putra, Stefanus Erdana; Hafizhan, Muhammad; Mirawati, Diah Kurnia; Budianto, Pepi; Subandi, Subandi; Danuaji, Rivan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 55, No 3 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005503202307

Abstract

Coronavirus disease 2019 (COVID-19) can cause systemic and respiratory symptoms. Acute respiratory distress syndrome (ARDS), anemia, acute heart injury, secondary infection, and stroke are the complications of COVID-19. Age, oxidative stress, endothelial dysfunction, inflammatory status, vascular risk factors, and hypoxemia are risk factors for stroke associated with COVID-19. In this case report, two cases of COVID-19 complicated by stroke and other thromboembolic diseases were discussed. Case 1: a 46-year-old man presented with right extremities weakness, dysarthria, cough, colds, chest pain radiating to left upper extremity. He was diagnosed with moderate COVID-19, with complication of embolic stroke and myocardial infarction. After administration of IV furosemid and recombinant tissue plasminogen activator (rTPA), his condition improved, and he was discharged from our facility. Case 2: a 54-year-old woman presented with a decreased level of consciousness, skin discoloration, tenderness on her left calf, cough, fever, and shortness of breath. She was diagnosed with moderate COVID-19 with a complication of thrombotic stoke and deep vein thrombosis (DVT). She was treated with rTPA, IV citicoline, and fondaparinux for 5 days. In conclusion, COVID-19 carries a risk of thromboembolic complication. COVID-19 patients have a higher risk of bleeding, therefore, medications, particularly anticoagulant, should be administered with more caution.
ANGIOPLASTIC STENOSIS IN SPONTANEOUS BILATERAL CAROTIC ARTERY DISSECTION: A CASE REPORT Subandi, Subandi; Danuaji, Rivan; Suroto, Suroto; Mirawati, Diah Kurnia; Budianto, Pepi; Hambarsari, Yetty; Hamidi, Baarid Luqman; Prabaningtyas, Hanindia Riani; Hutabarat, Ervina Arta Jayanti; Ristinawati, Ira; Tejomukti, Teddy; Tedjo, Raden Andi Ario; Santosa, Novian Anindito; Putra, Stefanus Erdana; Hafizhan, Muhammad
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.20

Abstract

Case: A 28-years-old woman presented with sudden right extremities weakness, right sided facial droop, and not being able to speak. On examination, the patient had upper motor neuron (UMN) hemiplegia and motor aphasia. On blood laboratory, we found D-dimer level of 1068 ng/dl. A non-contrast head CT-scan and CT-angiography showed left cerebral hemisphere infarction, and bilateral carotid artery stenosis. Further investigation with transcranial Doppler demonstrated partial stenosis of internal carotid artery (ICA). On cerebral digital subtraction angiography (DSA), we observed pseudoaneurysm on the right ICA and flame-shaped appearance on the left ICA, both are common radiological finding of ICA dissection. Then we performed stenting angioplasty on bilateral ICA to provide recanalization, and aspirin 80mg q.d. and clopidogrel 75mg q.d. was initiated. Conclusion: Spontaneous dissection of the carotid artery can occur on young adults. DSA is considered as the gold standard for vascular examination, and stenting with angioplasty was performed for recanalization to prevent the progression to severe stroke.
Correlation of electrolytes with falling risk, cognitive function, and functional outcome in acute ischemic stroke patient Mirawati, Diah Kurnia; Ristinawati, Ira; Prabaningtyas, Hanindia Riani; Tedjo, Raden Andi Ario; Putra, Stefanus Erdana; Hafizhan, Muhammad; Ilhamsyah, Rudi
International Journal of Public Health Science (IJPHS) Vol 13, No 3: September 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i3.23839

Abstract

Stroke outcome is determined on multiple factors. However, there are limited studies discussing the impact of electrolyte imbalance on stroke outcome. In this study, we analyzed sodium, calcium, and potassium level in acute ischemic stroke, and compare their risk of falling, cognitive function, and functional outcome. This was a cross-sectional study in Dr. Moewardi General Hospital, Indonesia between January and June 2023. Patient with acute ischemic stroke were enrolled in this study. Cognitive function was assessed with mini mental state examination (MMSE) and the Indonesian version of montreal cognitive assessment (MoCA-Ina). National Institutes of Health Stroke Scale (NIHSS), Modified Rankin Scale (MRS) and Morse Fall Score (MFS) were used to assessed stroke severity, disability, and risk of falling, respectively. Pearson correlation was then performed to evaluate the correlation of electrolytes level with MMSE, MoCA-Ina, NIHSS, MRS, and MFS. Furthermore, we also analyzed the odds ratio of increasing risk of falling, cognitive function deterioration, and worse functional outcome. A p-value of <0.05 is considered statistically significant. On univariate analysis, natrium is correlated with MMSE (r=0.174; p=0.042), NIHSS (r=-0.412; p=0.011), MRS (r=-0.174; p=0.042), and MFS (r=-0.304; p=0.042). Potassium is correlated with MMSE (r=0.344; p=0.044), MoCA-INA (r=0.341; p=0.048), NIHSS (r=-0.572; p=0.019), (MRS r=-0.376; p=0.017), and MFS (r=-0.612; p=0.031). Calcium is correlated with NIHSS r=-0.348 (p=0.018), MRS r=-0.256 (p=0.036). On odds ratio analysis, low natrium level increased the risk of deteriorating cognitive function, and low level of potassium increased the risk of falling. Electrolyte imbalances correlates with risk of falling and deteriorating cognitive function.
Association between vaspin rs2236242 gene polymorphism and atherosclerosis in ischemic stroke patients with diabetes mellitus in the Indonesian population Danuaji, Rivan; Suroto; Purwanto, Bambang; Indarto, Dono; Muhammad, Faizal; Mirawati, Diah Kurnia; Widyaningsih, Vitri; Soetrisno; Subandi; Budianto, Pepi; Hambarsari, Yetty; Hamidi, Baarid Luqman; Prabaningtyas, Hanindia Riani; Hutabarat, Ervina Arta Jayanti; Ristinawati, Ira; Tejomukti, Teddy; Tedjo, Raden Andi Ario
Medical Journal of Indonesia Vol. 33 No. 4 (2024): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.247566

Abstract

BACKGROUND Stroke is the third leading cause of morbidity and second in mortality worldwide. Diabetes mellitus (DM) is a risk factor for stroke. Vaspin and single nucleotide polymorphism (SNP) rs2236242 involved DM pathogenesis. This study aimed to explore the correlation between SNP rs2236242, serum vaspin levels, and atherosclerosis in patients with ischemic stroke and DM. METHODS This study was conducted in Dr. Moewardi Hospital from 2022 to 2023. The case group included patients with ischemic stroke and DM, while the controls were those with ischemic stroke only. Tetra-primer amplification refractory mutation system-polymerase chain reaction was used to determine the genotypes. RESULTS There were 31 cases and 33 control. SNP rs2236242 showed that odds ratio (OR) (95% confidence interval [CI]) for AA-TT was 0.273 (0.241–0.305) and for TA-TT was 0.315 (0.298–0.341). The OR (95% CI) for allele A to T was 0.789 (0.373−1.669). The mean (standard deviation) serum vaspin level in the case group compared to the control was 1,570 (2,108) ng/ml versus 1,630 (1,428) ng/ml (p = 0.064). Higher vaspin levels were found in T allele of the TT (1,523 [2,269] ng/ml, p = 0.021) and TA (1,760 [1,349] ng/ml, p = 0.004) genotype groups than the A allele of the AA genotype group (0.914 [0.329] ng/ml). CONCLUSIONS Vaspin gene polymorphism AA genotype or A allele significantly reduces vaspin levels in patients with ischemic stroke with DM.
MENINGKATKAN PENGETAHUAN PASIEN HIPERTENSI TENTANG PENCEGAHAN STROKE: PERBANDINGAN ANTARA TEMUAN EMPIRIS DAN TINJAUAN SISTEMATIS Ilhamsyah, Rudi; Prabaningtyas, Hanindia Riani; Yang, Han
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 42 No 1 (2025): Volume 42, No 1 - Desember 2025
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v42i1.798

Abstract

Abstract Background Stroke is leading cause of morbidity and mortality globally, particularly in developing countries where hypertension is a significant modifiable risk factor. The awareness of stroke risk factors among hypertensive patients crucial for effective prevention strategies. Hypertension is recognized as primary risk factor for stroke, contributing to approximately 70% of ischemic strokes globally. In Indonesia, the prevalence of hypertension is high, with studies indicating that 33.4% of individuals aged 43.3 years are affected, underscores the urgent need for enhanced awareness and education regarding stroke prevention. Research Objectives The primary objective of this research is to enhance knowledge of hypertensive patients regarding stroke prevention through two approaches: empirical study in Karanggeneng, Boyolali, and systematic review. Methods and Materials This study combining an empirical study conducted in Karanggeneng, Boyolali, with systematic review registered in PROSPERO (ID: CRD420251011016). The empirical study utilized pre and post-test design. Statistical analysis performed using Wilcoxon Signed Ranks Test. Results The empirical study revealed improved knowledge scores. Wilcoxon Signed Ranks Test yielded a Z value of -5.563 with an asymptotic significance <0.001, indicating a statistically significant increase in knowledge. The review reported improvements in knowledge following educational interventions, there were still notable gaps in awareness regarding stroke risk factors and prevention strategies. Conclusion This research underscores importance of educational intervention enhancing stroke knowledge. The findings from both the empirical study and the systematic review suggest that continuous education and awareness programs are essential for improving health outcomes, reducing the risk of stroke. Keywords: Stroke, Hypertension, Knowledge, Educational Intervention
Intracranial and Extracranial Vertebrobasilar Artery Stenosis Patient Profile in Dr. Moewardi General Hospital Subandi, Subandi; Suroto, Suroto; Mirawati, Diah Kurnia; Danuaji, Rivan; Budianto, Pepi; Hambarsari, Yetty; Hamidi, Baarid Luqman; Prabaningtyas, Hanindia Riani; Hutabarat, Ervina Arta Jayanti; Tejomukti, Teddy; Ristinawati, Ira; Tedjo, Raden Andi Ario; Pretikasari, Zefania Yonisa; Hafizhan, Muhammad; Putra, Stefanus Erdana
Smart Medical Journal Vol 6, No 3 (2023): December
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v6i3.71299

Abstract

Introduction: Vertebrobasilar artery stenosis can be extracranial or intracranial, and accounts for up to 20% of posterior circulation ischemic strokes. The gold standard for diagnosing is Digital Subtraction Angiography (DSA), an invasive diagnostic method by injecting a contrast agent into the blood vessels leading to the brain through a catheter. This study aims to determine the profile of patients with intracranial and extracranial vertebrobasilar artery stenosis who underwent DSA procedures.Methods: This descriptive research was conducted in RSUD Dr. Moewardi in patients who underwent DSA procedures for the period January 2020 to March 2022 and found vertebrobasilar artery stenosis. The study samples were grouped based on the location of the stenosis; intracranial and extracranial. The data collected included age, gender, symptoms, risk factors, degree of stenosis, and angiographic findings.Results: Of 42 subjects, 33 (78.6%) patients were male. There are 23 (54.8%) patients with intracranial vertebrobasilar stenosis and 19 (45.2%) patients in extracranial. The main symptoms included hemiparesis, vertigo, hemiesthesia, loss of consiciousness, aphasia, dysartria, and dysphagia. The risk factors were 36 (85.7%) patients with hypertension, 18 (42.9%) patients with diabetes mellitus, 18 (42.9%) patients with a history of smoking, and 13 (31%) patients with hyperlipidemia. A total of 8 patients underwent stenting/angioplasty.Conclusion: The prevalence of vertebrobasilar artery stenosis increases with age, most commonly occurring at the age of 50-59 years..The most common risk factor for vertebrobasilar artery stenosis is hypertension. Management recommendations include a combination of antiplatelet and endovascular therapy.
Pelatihan Pengisian Mini Mental State Examination (MMSE) dan Eight-item Informant Interview to Differentiate Aging and Dementia (AD8) untuk Deteksi Dini Demensia Alzheimer bagi Tenaga Kesehatan di Fasilitas Kesehatan Tingkat Pertama Ristinawati, Ira; Mirawati, Diah Kurnia; Subandi, Subandi; Danuaji, Rivan; Budianto, Pepi; Prabaningtyas, Hanindia Riani; Tedjo, Raden Andi Ario; Putra, Stefanus Erdana; Hafizhan, Muhammad
SEMAR (Jurnal Ilmu Pengetahuan, Teknologi, dan Seni bagi Masyarakat) Vol 11, No 2 (2022): November
Publisher : LPPM UNS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/semar.v11i2.66400

Abstract

Kegiatan ini bertujuan untuk  untuk meningkatkan pengetahuan dan kesadaran para tenaga kesehatan di fasilitas kesehatan tingkat pertama (FKTP) tentang pentingnya cara pengisian kedua instrumen tersebut dalam rangka deteksi dini demensia Alzheimer. Kegiatan ini juga bertujuan mengarahkan para tenaga kesehatan di FKTP untuk melakukan skrining pada pasien yang memiliki faktor risiko mengalami demensia Alzheimer sehingga tatalaksana dini yang lebih baik dapat diterapkan pada penderita demensia Alzheimer yang tentunya dapat meningkatkan kualitas hidup pasien tersebut. Target yang dicapai adalah peningkatan pemahaman dan informasi terkait cara pengisian MMSE dan AD8 dan manfaat skrining demensia Alzheimer. Metode pelaksanaan kegiatan pemberdayaan dan pengabdian masyarakat pada mitra berupa pemetaan demografi tenaga kesehatan FKTP potensial yang dilanjutkan dengan koordinasi dan kolaborasi dengan bagian Diklit RSUD Dr. Moewardi Surakarta untuk promosi dan pelaksanaan pelatihan daring. Selanjutnya, peneliti melakukan pelatihan dengan cara menjelaskan cara pengisian MMSE dan AD8 serta manfaat skrining demensia Alzheimer, simulasi interaktif cara pengisian MMSE dan AD8 dengan probandus, diskusi dan tanya jawab, serta evaluasi. Hasil pengabdian ini menunjukkan bahwa para tenaga kesehatan memiliki pemahaman yang meningkat dibandingkan sebelum pelatihan tentang cara dan manfaat pengisian MMSE dan AD8 dalam skrining demensia Alzheimer, sehingga meningkatkan kesadaran para tenaga kesehatan di FKTP akan dampak buruk peningkatan kejadian demensia Alzheimer yang dapat timbul akibat keterlambatan diagnosis. Kata kunci: demensia Alzheimer; pelatihan; tenaga kesehatan; MMSE; AD8
Efektifitas Promosi Kesehatan Menggunakan Video Senam Rehabilitasi Vestibuler untuk Mengurangi Keluhan Vertigo di Masa Pandemik Mirawati, Diah Kurnia; Tedjo, Raden Andi Ario; Budianto, Pepi; Prabaningtyas, Hanindia Riani; Ristinawati, Ira; Subandi, Subandi; Danuaji, Rivan; Hafizhan, Muhammad; Putra, Stefanus Erdana
SEMAR (Jurnal Ilmu Pengetahuan, Teknologi, dan Seni bagi Masyarakat) Vol 12, No 2 (2023): November
Publisher : LPPM UNS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/semar.v12i2.68328

Abstract

Vertigo merupakan sensasi gerakan atau rasa gerak dari tubuh seperti sensasi berputar namun tanpa adanya sensasi berputar yang sebenarnya. Vertigo paling sering disebabkan oleh disfungsi pada sistem vestibular dari lesi perifer maupun sentral. pada masa pandemi COVID-19 sebagian besar pasien vertigo mengalami kesulitan untuk rutin memeriksakan diri di rumah sakit. Oleh karena itu, dicari alternatif berupa perawatan non farmakologis agar pasien bisa tetap mengontrol keluhan penyakitnya di masa pandemi ini. Senam rehabilitasi vestibular melatih otak melalui petunjuk visual dan proprioseptif alternatif untuk menjaga keseimbangan. Penelitian ini dibuat untuk mengetahui efektifitas promosi kesehatan menggunakan video senam rehabilitasi vestibuler untuk mengurangi keluhan vertigo. Penyelenggaran penyuluhan pada anggota posyandu lansia ANTHURIUM, Kelurahan Tegalrejo yang diikuti sebanyak 47 orang. Sebelum dan sesudah penyuluhan dilakukan evaluasi terkait pengetahuan peserta mengenai vertigo melalui pretest dan posttest. Data hasil evaluasi menunjukkan adanya perbaikan pengetahuan peserta dari skor rata rata awal 62.4 menjadi 83.7.
Efektivitas Promosi Kesehatan Menggunakan Leaflet Nyeri Punggung Bawah untuk Mengurangi Keluhan Nyeri Punggung di Masa Pandemik Mirawati, Diah Kurnia; Prabaningtyas, Hanindia Riani; Budianto, Pepi; Subandi, Subandi; Danuaji, Rivan; Hamidi, Baarid Luqman
SEMAR (Jurnal Ilmu Pengetahuan, Teknologi, dan Seni bagi Masyarakat) Vol 11, No 2 (2022): November
Publisher : LPPM UNS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/semar.v11i2.56217

Abstract

Nyeri punggung  bawah  (NPB) adalah  suatu keadaan  tidak  nyaman  atau  rasa  nyeri  yang  akut  pada  di  daerah  ruas lumbalis  kelima  dan  sakralis pertama (L5-S1). Kebijakan social distancing pada masa pandemi COVID-19 diberlakukan untuk menurunkan angka infeksi COVID-19, namun hal ini memunculkan masalah baru seperti nyeri musculoskeletal yang terjadi karena kurangnya aktivitas fisik individu. Pandemi COVID-19 juga secara signifikan mengurangi akses pasien untuk mendapatkan pengobatan di fasilitas kesehatan untuk mengatasi nyeri punggung yang dialami. Hal ini mendorong peneliti untuk mengembangkan media edukasi untuk tatalaksana mandiri untuk pasien dengan NPB. Pada pengabdian masyarakat ini, peneliti menyusun materi edukasi mengenai rehabilitasi NPB yang dapat dilakukan di rumah. Kami mengukur skala nyeri dan kualitas hidup pasien sebelum dan sesudah edukasi. Skala nyeri pasien diukur dengan Numeric Rating Scale (NRS), sedangkan kualitas hidup pasien dinilai dengan The World Health Organization Quality of Life – BREF (WHOQOL-BREF). Uji T-test dependen menunjukkan terdapat penurunan intensitas nyeri (p=0.000) dan perbaikan kualitas hidup peserta (p=0.000) setelah edukasi. Kata kunci: nyeri punggung bawah; pengabdian masyarakat; pendidikan
Co-Authors Bambang Purwanto Budianto, Pepi Diah Kurnia Mirawati Dono Indarto Hafizhan, Muhammad Hambarsari, Yetty Hamidi, Baarid Luqman Han Yang Hapsari, Maria Yosita Ayu Hutabarat, Ervina Arta Jayanti Ilhamsyah, Rudi Ira Ristinawati Muhammad, Faizal Novian Anindito Santosa Pretikasari, Zefania Yonisa Rivan Danuaji Soetrisno Stefanus Erdana Putra Subandi Subandi SUROTO Suroto Suroto Tedjo, Raden Andi Ario Tejomukti, Teddy Vitri Widyaningsih