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All Journal Jurnal Farmasi Higea Jurnal Katalisator JOURNAL OF COMMUNITY SERVICE AND APPLICATION SCIENCE (JCSAS) Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Irene Puspa Dewi
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Formulasi dan Evaluasi Gel Infusa Daun Belimbing Wuluh Verawaty Verawaty; Irene Puspa Dewi; Felicia Febrian CH
Jurnal Farmasi Higea Vol 12, No 2 (2020)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52689/higea.v12i2.309

Abstract

Pada Daun belimbing wuluh terkandung senyawa flavonoid, saponin dan tanin yang berfungsi sebagai antibakteri. Tujuan dari penelitian ini adalah untuk menformulasi daun belimbing wuluh menjadi sediaan gel yang baik, efektif, dan aman untuk digunakan, serta menguji efektivitasnya terhadap pertumbuhan bakteri Staphylococcus epidermidis. Sediaan gel yang didapatkan berupa gel berwarna bening dan kuning bening, tidak memiliki bau, homogen, pH formula 1, 2 dan 3 berturut-turut 5,60, 5,58 dan 5,54 dan tidak mengiritasi kulit. Hasil penelitian ini menunjukkan bahwa sediaan gel dari infusa daun belimbing wuluh memiliki daya hambat antibakteri terhadap bakteri Staphylococcus epidermidis pada formula 1 (10%), 2 (20%) dan 3 (30%) dengan rata-rata diamter zona hambat 10,6 mm, 12,3 mm, dan 29,1 mm. Hal ini menunjukkan pada formula 3 (30%) merupakan konsentrasi yang efektif dalam menghambat pertumbuhan bakteri Staphylococcus epidermidis. Uji One Way Anova dalam program Statistical Product And Service Solution (SPSS) 16.0 for Windows, hasilnya menunjukkan bahwa terdapat perbedaan rata-rata diameter zona hambat pada konsentrasi kelompok adalah signifikan dengan nilai  0,003 (α < 0,005).
Perbandingan Metode Sokletasi dengan Maserasi terhadap Daya Aktivitas Antioksidan Bunga Tasbih (Canna hybrida Hort.) Irene Puspa Dewi; Siti Maisaroh; Verawaty Verawaty
Jurnal Farmasi Higea Vol 12, No 1 (2020)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (941.851 KB) | DOI: 10.52689/higea.v12i1.263

Abstract

Bunga tasbih mengandung antosianin yang merupakan suatu senyawa yang termasuk golongan flavonoid. Antosianin dapat dimanfaatkan sebagai antioksidan. Antioksidan merupakan senyawa yang menghambat, mencegah dan menghilangkan kerusakan oksidatif pada molekul target. Untuk mendapatkan senyawa antosianin, dilakukan proses ekstraksi yang memiliki berbagai macam metode. Metode ekstraksi yang beranekaragam tersebut memiliki kelebihan dan kekurangan masing-masing. Penelitian ini bertujuan untuk membandingkan metode sokletasi dengan maserasi terhadap daya antioksidan ekstrak etanol bunga tasbih. Metode pengujian daya antiosidan ekstrak etanol bunga tasbih yang digunakan adalah metode DPPH. Hasil penelitian yang didapat adalah IC50 ekstrak etanol bunga tasbih yang diektraksi dengan metode sokletasi adalah 26,5 µg/mL dan termasuk memiliki daya antioksidan yang sangat kuat. IC50 ekstrak etanol bunga tasbih yang diekstraksi dengan metode maserasi adalah 32,7 µg/mL dan termasuk memiliki daya antioksidan yang kuat. Sebagai pembanding digunakan Vitamin C yang memiliki IC50 adalah 5,3 µg/mL dan termasuk memiliki daya antioksidan yang sangat kuat. Dari data tersebut, disimpulkan bahwa daya antioksidan ekstrak etanol bunga tasbih yang diekstraksi dengan metode sokletasi lebih kuat dibandingkan daya antioksidan ekstrak etanol bunga tasbih yang diekstraksi dengan metode maserasi.
EFEKTIVITAS GEL EKSTRAK AIR UMBI BAWANG PUTIH TERHADAP PENYEMBUHAN LUKA BAKAR DAN LUKA SAYAT Irene Puspa Dewi; Verawaty Verawaty; Tuty Taslim
Jurnal Ilmiah Manuntung Vol 6 No 2 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i2.356

Abstract

This study was conducted to determine the effectiveness of garlic (Allium sativum L.) extract gel for healing burns and cuts. Garlics are often used in healing wound because they contained sulfur in garlic, namely Diallyl thiosulfinate (allicin) and Diallyl disulfide (ajoene). Allicin in garlic will reduce inflammatory reactions and antibacterial, which will accelerate in healing wound. Garlics extract made in gel preparations with a concentration of 15% and 20%, then given to burns and cuts mice that have been divided into several groups. In testing, mice that had been made burns were divided into 4 groups and each group contain of 3 mice, namely the 15%, 20% concentration gel group. The Bioplacenton group as a comparison and also the control group. In the examination of cuts, the division of the group of mice that have been made the cuts is the same as the burn test, the comparison is Povidone iodine. From the burn test, the results are the 20% concentration gel group experienced the best healing after 18 days of gel administration and its healing power was better than Bioplacenton. The results of cuts testing is the 15% concentration gel group experienced the best healing and slightly better than Povidone Iodine.
FORMULASI DAN EVALUASI SEDIAAN MASKER SHEET EKSTRAK ETANOL DAUN SIRIH MERAH (Piper crocatum Ruiz & Pav) Verawaty Verawaty; Novita Sulimar; Irene Puspa Dewi
Jurnal Ilmiah Manuntung Vol 6 No 2 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i2.357

Abstract

The research was conducted on ethanol extract formulation of red betel leaves (Piper crocatum Ruiz & Prav.). This research aims to formulate the ethanol extract of red betel leaves (Piper crocatum Ruiz & Prav.) to be a dosage of good, effective, and safe sheet mask to use. This research was experimental, in which 12 women aged 18-25 years old were selected to test for irritation that was observed on the skin behind the ear. To test the effectiveness, the observed dosage was facial skin moisture in the T. The results obtained are in the form of an essence that is slightly thick, brown in color, having a distinctive smell of red betel leaf extract, homogeneous, and safe for the skin. For the effectiveness, the test showed that the sheet mask of red betel leaf extract in formula 1 (1%), formula 2 (3%) and formula 3 (5%) were able to increase facial skin moisture. The analysis results showed that there was a significant difference in the average measurement of water content on the volunteers' facial skin of 0.01 (α <0.05).
Dagusibu And Pkrt Health Counseling In The Surrounding EnvironmentFor Wkri Dpd West Sumatra: Penyelenggaraan Kesehatan Dagusibu Dan Pkrt Di LingkunganLingkungan Rwkri Dpd Sumatera Barat Reny Salim; Tuty Taslim; Irene Puspa Dewi; Fita Selonni
Journal of Community Service and Application of Science Vol. 1 No. 1 (2022): JOURNAL OF COMMUNITY SERVICE AND APPLICATION SCIENCE (JCSAS)
Publisher : KPN Kopertis X

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/yaz9n723

Abstract

Mothers need knowledge of the treatment and use of PKRT according to the rules. This is important considering that the mother is the individual responsible for taking care of the family's needs. The expert must welcome the fulfillment of these mothers' needs must be received through devotional activities. One form of service activity that mothers can do is health counselling which aims to measure the influence of counselling on changes in participants' attitudes. The participants in this counselling are the categorial group of WKRI DPD West Sumatra The method used is offline and online interactive counselling. The supporting media used are Microsoft PowerPoint, Quiziz, and Zoom. The data collection method used is pretest-posttest. The results obtained in the counseling activity were a change in participants' attitudes before and after counseling with a signification value of p<0.05. It means that there is a need for interactive counseling on drugs and PKRT that can help improve public health and lower long-term adverse risks.
ANTIOXIDANT CAPACITY TEST & QUALITY EVALUATION OF HAND BODY LOTION KEDONDONG JUICE (Spondias dulcis Parkinson) Taslim, Tuty; Reny Salim; Irene Puspa Dewi; Fita Selonni
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2768

Abstract

Kedondong (Spondias dulcis Parkinson) is a tropical fruit known for its rich vitamin C content and associated antioxidant activity. The challenges will maximize the benefits of vitamin C in kedondong fruit soluble in water, and the light will degrade and reduce its effectiveness as an antioxidant. Previous research has highlighted that the heating process affected the antioxidant activity and the ethanol extract kedondong is used to make hand body lotion. This research aims to exploit the potential of using kedondong fruit in the formulation of hand body lotion by utilizing its antioxidant activity. The study used the FRAP method using Trolox as a synthetic antioxidant so that the antioxidant capacity of kedondong juice hand body lotion is obtained which was equivalent to TEAC (Trolox Equivalent Antioxidant Capacity). The results obtained from the hand body lotion preparation of kedondong fruit juice were 4.5 mM TE⁄gram, while kedondong fruit juice was 23.04 mM TE⁄gram. The results of the quality evaluation test of hand body lotion preparations have good homogeneity, do not cause irritation, have stable pH, and have a moisturizing effect on the skin.
Co-Authors Felicia Febrian CH Fita Selonni Novita Sulimar Reny Salim Siti Maisaroh Tuty Taslim Tuty Taslim Verawaty Verawaty Verawaty, Verawaty