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All Journal Jurnal Keperawatan Jiwa (JKJ): Persatuan Perawat Nasional Indonesia Jurnal Sains dan Teknologi Farmasi Indonesian Journal of Pharmaceutical Science and Technology JURNAL KESEHATAN PERINTIS Jurnal Riset Kefarmasian Indonesia JAFP (Jurnal Akademi Farmasi Prayoga) Jurnal Pengabdian kepada Masyarakat (ABDIKEMAS) Jurnal Katalisator Jurnal Ilmiah Farmasi Simplisia
Tuty Taslim
Akademi Farmasi Prayoga Padang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Studi Sistem Dispersi Padat Isoxsuprine Hcl Povidon K-30 Taslim, Tuty; Halim, Auzal; Suardi, Muslim
Jurnal Sains dan Teknologi Farmasi Vol 15 No 1 (2010)
Publisher : Fakultas Farmasi Universitas Andalas

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Abstract

A study on Solid Dispersion System of Isoxsuprine HCl by using syntetic polymer Povidon K-30 to increase solubility has been done has been done. The solid dispersion system were prepared by using solvent method with any comparison ( Taslim, 2007). Charactheristics of physical chemistry properties of solid dispersion such as dissolution test, X-ray diffraction analysis, Differential Scanning Calorimetry, and Fourier Transform Infra Red were assayed. The dissolution test from solid dispersion by using UV spectrophotometer. Statistical analysis of solid dispersion’s dissolution test was done by using Anova. The characteristic X-ray’s diffraction and FTIR showed that solid dispersion with drug to polimer ratio of 1:9 ; 2:8 ; 3:7 were amorf in comparison to other solid dispersions. Statistical analysis by one direction Anova concluded that the dissolution profile of the solid dispersion system of 2:8 was the highest.
GAMBARAN PEMBERIAN OBAT PADA PENDERITA HIPERTENSI DI PUSKESMAS RAWANG Taslim, Tuty; Betris, Yani Anggela
Jurnal Riset Kefarmasian Indonesia Vol 2 No 2 (2020): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v2i2.81

Abstract

Hypertension is a disease that often causes death because many people do not realize it. People have hypertension if the blood pressure above 140/90 mmHg after regular checking. In Puskesmas Rawang, hypertension is the second-highest disease. This study aims to overview drug administration in patient's hypertension. This research is an observational descriptive study using retrospective data with the inclusion criteria. Data was taken from the recipes in April till June 2019 period. Based on the research, 82 % of women more suffer than men. While the age criteria from 41 – 61 years was 53.8%. The majority of drugs were given in Puskesmas Rawang was amlodipine with a percentage of 89%.
Uji Daya Larut Kalsium Oksalat Dalam Infus Daun Alpukat Tuty Taslim; Efrianti B W
Jurnal Akademi Farmasi Prayoga Vol 1 No 1 (2016): Jurnal Akademi Farmasi Prayoga
Publisher : Jurnal Akademi Farmasi Prayoga

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Abstract

Telah dilakukan penelitian uji daya larut Kalsium Oksalat dalam infus daun alpukat (Persia americana Mill). Perendaman 100 mg Kalsium Oksalat dalam larutan 10% infusa daun alpukat dilakukan selama 7 hari berturut-turut. Dan dilakukan penghitungan kadar kalsium terlarut dengan metoda kompleksometri dengan titrasi kembali menggunakan Na2 EDTA berlebih. Hasil penelitian menunjukkan infusa daun alpukat dapat melarutkan kalsium oksalat dan terlihat adanya peningkatan kadar kalsium oksalat terlarut dengan variasi waktu.
GAMBARAN RESEP OBAT OFF LABEL PASIEN BALITA DI SALAH SATU APOTEK SWASTA PADANG PERIODE JANUARI-APRIL 2017 Tuty Taslim; Talitha Rhinarda; Reny Salim
Jurnal Akademi Farmasi Prayoga Vol 5 No 1 (2020): Jurnal Akademi Farmasi Prayoga Padang
Publisher : Jurnal Akademi Farmasi Prayoga

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Abstract

Resep off label adalah obat-obat yang dituliskan oleh dokter yang tidak sesuai dengan ketentuan izin penjualan dari marketing authorisation (MA). Peresepan obat off label dapat dikatakan tidak legal, tetapi jelas merupakan masalah yang perlu diperbaiki berkaitan dengan dosis, rute pemberian, indikasi dan kontraindikasi. Anak balita merupakan kelompok usia yang mempunyai daya metabolisme yang berbeda dengan daya metabolisme pada orang dewasa sehingga kemungkinan pemberian obat yang sama pada anak akan menimbulkan respon yang berbeda. Untuk itu dilakukan penelitian tentang gambaran resep obat off label pada pasien balita di salah satu apotek swasta di Padang pada periode Januari-April 2017 dengan metode observasional secara retrospektif. Tujuanpenelitian adalah untuk mengetahui gambaran peresepan obat off label pada pasien balita berdasarkan brosur obat, PIO (Pelayanan Informasi Obat), ISO (Informasi Spesialite Obat), MIMS (The Monthly Index of Medical Specialities). Gambaran obat off label akan diamati berdasarkan kriteria dosis dan umur. Dari 122 lembar sampel yang dianalisis terkandung 633 jenis item obat dimana obat off label tertinggi adalah Dexamethason tablet sebesar 11%, sedangkan persentase penggunaan obat off label pada kriteria dosis sebesar 36,1% dan pada kriteria usia sebesar 9,8%.
ANALISIS DAYA ANTIOKSIDAN SENYAWA METABOLIT SEKUNDER EKSTRAK ETANOL DAUN SURIAN (Toona sinensis(Juss) M.Roem) Tuty Taslim; Riyandi H Pratama
Jurnal Akademi Farmasi Prayoga Vol 5 No 2 (2020): Jurnal Akademi Farmasi Prayoga Vo.5 No.2 Tahun 2020
Publisher : Jurnal Akademi Farmasi Prayoga

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Abstract

ABSTRAK Pohon surian atau Toona sinensis adalah salah satu spesies dari keluarga mahoni yang dikenal sebagaimahoni Indonesia yang memiliki berbagai khasiat.Bagian-bagian tanaman surian seperti daun, akar,dan kulit memiliki banyak komponen bioaktif yang dapat berperan sebagai antioksidan, antikanker,dan anti diabetes. Penelitian sejenis tentang aktifitas kandungan metabolit sekunder dari kulit kayudan ekstrak daun surian Toona sinensis (Juss.) M.Roem yang telah dilakukan adalah dengan caramaserasi dengan etanol 70% dan maserasi menggunakan pelarut metanol yang dilanjutkan denganfraksinasi dengan dietil eter, tetapi pada penelitian ini ekstrak daun surian dilakukan dengan metodesokletasi menggunakan pelarut etanol 70%. Dari hasil uji fitokimia kandungan yang terdapat dalam daun surian adalah alkaloid, flavonoid, polifenol dan terpenoid. Sedangkan intensitas kekuatanantioksidan yang berpotensi untuk menghambat radikal bebas DPPH(1,1-difenil-2-pikrilhidrzil)diukur kemampuan peredamannya dengan menggunakan alat spektrofotometer UV visible.Didapatkan nilai IC50 ekstrak daun surian sebesar 10,45 µg/mL yang termasuk pada kategoriintensitas kekuatan anti oksidan yang sangat kuat, meskipun relatif tidak sekuat vitamin C yangmempunyai nilai IC50 sebesar1,71 µg/mL.
Daya Hambat Hand Sanitizer di Masyarakat: Apakah Efektif ? Tuty Taslim; Reny Salim; Irene Puspa Dewi
Jurnal Riset Kefarmasian Indonesia Vol 4 No 2 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i2.250

Abstract

Hand sanitizer is one of the Household Health Supplies (PKRT) which is one of the human needs when the Covid-19 pandemic appears throughout the world. Panic at the beginning of the spread of Covid-19 has caused many people to buy and store hand sanitizers, resulting in shortages everywhere. WHO announced the composition for the manufacture of hand sanitizers. And the government allows making hand sanitizers without going through actual regulations so that hand sanitizers appear in several dosage forms such as sprays and gels suitable for antiseptic purposes. The inhibition of hand sanitizers against microbes needs to be tested considering its function as a microbial exterminator on human hands, so this research needs to be done to determine the effectiveness of hand sanitizers circulating in the community. The microbes used are Staphylococcus aureus and Escherichia coli. The sampling technique was carried out by purposive sampling and its effectiveness by using the disc diffusion method. The results obtained are that all hand sanitizers sampled have a diameter of inhibition as a strong antiseptic 10%, 50% sufficient and 40% weak.
AKTIVITAS IMUNOMODULATOR EKSTRAK ETANOL DAUN JAMBU BIJI (Psidium guajava L.) Irene Puspa Dewi Dewi; Verawaty; Tuty Taslim
JURNAL KATALISATOR Vol. 7 No. 1 (2022): Jurnal Katalisator Volume 7 Nomor 1, April 2022
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (305.533 KB) | DOI: 10.22216/katalisator.v7i1.720

Abstract

This study was aimed to assess immunomodulatory activity of guava leaf (Psidium guajava L.) ethanol extract. Guava leaves contain flavonoid compounds that can be used as immunomodulators. The parameters to be determined were the percentage of phagocytosis and the phagocytic capacity of mouse macrophage cells. A total of 25 mice were divided into 5 groups, namely a negative control, a positive control, a dose100 mg/Kg BW, a dose of 500 mg/Kg BW, and a comparison group. The mice were treated according to their respective groups for 7 days and on the 8th day the mice were injected intraperitoneally with Staphylococcus aureus (SA) bacteria suspension, except for the negative control group. After 1 hour, mice in all groups were sacrificed and their peritoneal fluid were taken to calculate the percentage of activity and phagocytic capacity. The results of the percentage of activity and phagocytic capacity of macrophage cells in the peritoneal fluid in the negative control group was 64.9% and 93.2 %, the positive control group was 66.2% and 95.0%, the 100 mg/kg BW dose group was 75.0% and 111.0%, the 500 mg/kg BW group was 82.8% and 134.6%, and the comparison group was 86.5% and 176.6%. Statistically, the percentage of activity and phagocytic capacity of mice at a dose of 100 mg/kg BW and a dose of 500 mg/kg BW were significantly different from the negative control group and the positive control group. It can be concluded that at doses of 100 mg/kg BW and 500 mg/kg BW, guava leaf ethanol extract can increase the activity and phagocytic capacity of mice.
Remaja Kecanduan Rokok: Studi Fenomenologi Salim, Reny; Taslim, Tuty; Selonni, Fita
Jurnal Keperawatan Jiwa Vol 12, No 2 (2024): Mei 2024
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jkj.12.2.2024.351-358

Abstract

Kecanduan remaja terhadap rokok tidak dapat diselesaikan. Kecanduan ini memberikan dampak buruk bagi kesehatan dan lingkungan. Penelitian ini bertujuan untuk mendapatkan informasi terhadap persepsi remaja  yang kecanduan merokok. Pendekatan yang digunakan adalah kualitatif studi fenomenologi. Teknik sampling digunakan adalah purposive sampling. Teknik pengumpulan data adalah wawancara mendalam. Jumlah partisipan didasarkan pada kejenuhan data. Hasil penelitian ini memberikan informasi alasan dari kecanduan remaja terhadap rokok yaitu persepsi terhadap rokok, pengetahuan terhadap rokok, dan kepedulian terhadap lingkungan. Upaya penurunan persentase perilaku merokok pada remaja membutuhkan dukungan dari berbagai pihak dengan tegas.
Aktivitas Antioksidan Masker Gel Peel-off Ekstrak Rimpang Temu Ireng (Curcuma aeruginosa Roxb.) Dewi, Irene Puspa; Verawaty, Verawaty; Taslim, Tuty; Sinabutar, Pola Paulina
JURNAL KESEHATAN PERINTIS Vol 11 No 1 (2024): Jurnal Kesehatan Perintis
Publisher : LPPM UNIVERSITAS PERINTIS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33653/jkp.v11i1.1076

Abstract

Temu ireng (Curcuma aeruginosa Roxb.) mengandung senyawa flavonoid yang memiliki daya antioksidan dan dapat dijadikan sediaan masker gel peel-off. Tujuan penelitian ini yaitu untuk mengetahui aktivitas antioksidan masker gel peel-off ekstrak rimpang temu ireng menggunakan metode DPPH (1,1-diphenyl-2-picrylhydrazyl). Ekstrak rimpang temu ireng diperoleh dengan cara maserasi menggunakan etanol 70%. Ekstrak rimpang temu ireng dimanfaatkan sebagai bahan aktif dalam pembuatan masker gel peel-off. Metode DPPH digunakan untuk menentukan aktivitas antioksidan berdasarkan nilai IC50. Nilai IC50 ekstrak rimpang temu ireng sebesar 746,75μg/mL, nilai IC50 masker gel peel-off ekstrak rimpang temu ireng sebesar 5.569,90μg/mL, dan nilai IC50 vitamin C sebesar 24,65μg/mL. Dari hasil penelitian disimpulkan bahwa masker gel peel-off ekstrak rimpang temu ireng memiliki aktivitas antioksidan berdaya sangat lemah dengan IC50 5.569,90μg/mL.
Decoction of Cocos nucifera Linn. : Antioxidant Activity, Total Phenolics, and Flavonoids Contents Salim, Reny; Taslim, Tuty; Selonni, Fita; Verawaty, Verawaty; Dewi, Irene Puspa
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 2 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i2.45058

Abstract

Young coconut husk is one of the wastes that can be processed as a source of herbal medicine. Previous research on young coconut husk has provided information about its tannin content, antioxidant activity, and other bioactivities. This study aims to measure antioxidant activity and total phenolic and flavonoid contents from young coconut husk decoction. The determination of antioxidant activity and total phenolic and flavonoid contents used successively were DPPH, Folin-Ciocalteu, and aluminium chloride methods. The antioxidant activity test of young coconut husk decoction revealed an IC50 value of 47.69 µg/mL. The analysis of total phenolic and flavonoid content in the decoction showed 46,43 mg GAE/gram of husk powder and 4.04 mg RE/gram of husk powder, respectively. Collectively, young coconut husk extracted by decoction has strong antioxidant activity and can be used as a source of phenolics and flavonoids.
Co-Authors Aschel, Permata Auzal Halim Betris, Yani Anggela Efrianti B W Enjelita, Santa Fita Selonni Irene Puspa Dewi Irene Puspa Dewi Irene Puspa Dewi Dewi Irene Puspa Dewi, Irene Puspa Manurung, Tumpal Muslim Suardi Puspa Dewi, Irene Reny Salim Riyandi H Pratama Salim, Reny Selonni, Fita Sinabutar, Pola Paulina Talitha Rhinarda Verawaty Verawaty Verawaty Verawaty, Verawaty