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IDENTIFIKASI PARASETAMOL DALAM JAMU PEGAL LINU YANG DIPEROLEH DARI DEPOT JAMU DI KOTA DENPASAR Ni Made, Maharia Ningsih
Jurnal Riset Kefarmasian Indonesia Vol 4 No 1 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i1.208

Abstract

The use of traditional medicine in the form of herbal medicine is in great demand by the people of Indonesia, one of that is pegal linu herb. Based on PERMENKES No. 006/Menkes/Per/V/2012 articles 33 and 37 states that traditional medicine may not contain medicinal chemical. Medicinal chemical that is often added into herbal medicine for pegal linu herb is paracetamol.This study aims to determine the presence of paracetamol in pegal linu herb depots in Denpasar city. The research method used an exploratory descriptive method and samples of herbal medicine were taken by purposive sampling, 14 samples of herbal medicine of various brands that was sold at depots in Denpasar City. The research was conducted at the chemical laboratory of Bali International University in July 2021. After preparation, the fourteen samples of herbal medicine were identified using Thin Layer Chromatography (TLC) with selection mobile phase ethanol p.a, detection with UV light 254 nm and 0.05 M H2SO4 sprayer. Completeness identification was also carried out descriptive labeling of herbal products containing paracetamol. Positive samples contain paracetamol if the Rf value and spot color are similar to the paracetamol comparison standard. The Rf results obtained that samples with codes F, I, K, and L were 0.68; 0.68; 0.68 and 0.68 which are the similar as the standard Rf for comparison of paracetamol and positive control which is 0.69. The conclusion of the research is that there are various brands of pegal linu herb sold in Indonesia that are suspected to contain 4 brands of paracetamol. Research suggestions for consumers who consume a brand of traditional herbal medicine are expected to be more selective in choosing herbal medicine by first checking the product registration number.
Pengaruh Pemberian Aromaterapi Kayu Manis terhadap Intensitas Nyeri Dismenore Primer pada Remaja Ni Made Maharianingsih; Ni Made Dewi Poruwati
Jurnal Ilmiah Medicamento Vol 7 No 1 (2021): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v7i1.1262

Abstract

Gangguan haid akibat dismenore primer sering timbul pada usia remaja dengan prevalensi kejadian 89,5%. Dismenore primer disebabkan oleh pelepasan prostaglandin yang berlebihan sehingga terjadi spasme uterus dan mengakibatkan nyeri saat menstruasi. Obat antiinflamasi nonsteroid (OAINS) sering digunakan untuk terapi awal mengurangi nyeri dismenorea primer, namun menimbulkan efek samping pada gastrointestinal. Penggunaan aromaterapi dengan essential oil dapat digunakan sebagai alternatif terapi selain obat untuk mengatasi dismenorea primer. Essential oil yang dapat digunakan adalah kayu manis yang memiliki efek antispasmodic melalui kandungan cinnamaldehyde (55-57%) dan eugenol (5-18. Tujuan penelitian adalah mengetahui pengaruh pemberian aromaterapi kayu manis terhadap penurunan intensitas nyeri dismenore primer. Penelitian ini menggunakan rancangan one-group pretest-posttest design. Intensitas nyeri diukur dengan Wong Baker Rating Scale. Responden penelitian sebanyak 30 responden remaja yang merupakan siswi SMAN 1 Sukawati. Teknik pengambilan subjek dengan probability sampling. Analisa data menggunakan uji Wilcoxon. Diperoleh hasil yaitu sebelum pemberian aromaterapi kayu manis (pretest), responden mengalami intensitas nyeri ringan (10%), sedang (73%), dan berat (17%). Setelah dilakukan pemberian aromaterapi kayu manis (posttest), responden mengalami penurunan intensitas nyeri dengan derajat nyeri ringan (83%) dan sedang (17%) dengan nilai p=0,000. Disimpulkan bahwa terdapat pengaruh signifikan pemberian aromaterapi kayu manis terhadap penurunan intensitas rasa nyeri pada remaja yang mengalami dismenore primer.
Hubungan Pengetahuan dengan Perilaku Swamedikasi Obat Antinyeri di Apotek X di Kota Denpasar: berdasarkan Theory of Planned Behavior (TPB) Ni Made Maharianingsih; Ni Luh Mia Jasmiantini; Gde Palguna Reganata; Ni Putu Aryati Suryaningsih; I Gusti Ayu Rai Widowati
Jurnal Ilmiah Medicamento Vol 8 No 1 (2022): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v8i1.2115

Abstract

Self-medication behavior is usually carried out to deal with complaints and minor ailments that many people experience, such as fever, pain, dizziness, cough, influenza, stomach ulcers, intestinal worms, diarrhea, skin diseases and others. The formation of behavior is influenced by knowledge. Behavior can be researched using the Theory of Planned Behavior (TPB) method. The purpose of this study was to determine the relationship between the level of knowledge and the behavior of self-medication of analgesic medication at Pharmacy X in Denpasar City. This study uses a survey method with a cross sectional approach. The sampling technique in this study used the convenience sampling method with the number of respondents in this study as many as 276 people with inclusion criteria, namely respondents who used pain medication without a doctor's prescription, aged 15-65 years, could read and write, were willing to fill out a questionnaire while the exclusion criteria were respondents with mental and physical disabilities.The instrument used in this study was a self-medication knowledge and behavior questionnaire that had been tested for validity and reliability with valid and reliable results. The data obtained were analyzed by the Somers'd correlation method because both use an ordinal scale. The results showed that the level of knowledge of the respondents was high 37,3%, moderate 33,7%, and low 29%. Respondents' behavior was divided into 3 categories of TPB, attitudes towards behavior with moderate results (47,1%), subjective norms with high results (43,1%) and behavioral control with high results (48,9%). The results of the correlation test show a significance value (p-value) of 0.000 (p<0.05), which means that there is a significant relationship. The conclusion of this study is that there is a relationship between the level of knowledge and the behavior of self-medication of analgesic medication at Pharmacy X in Denpasar City.
EVALUASI PENGGUNAAN OBAT ANEMIA PADA PASIEN PENYAKIT GINJAL KRONIK DENGAN HEMODIALISA DI RSU ARI CANTI PADA TAHUN 2020 Ni Kadek Sulistya Dewi; Ni Made Maharianingsih
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 10 No 2 (2021): MEDFARM: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v10i2.58

Abstract

Penyakit ginjal kronik (PGK) menjadi perkara nyata dalam dunia medis dengan peningkatan prevalensi secara terus-menerus. Tindakan medis yang dilakukan pada pasien PGK ialah hemodialisis, tindakan ini dilakukan untuk mengganti fungsi ginjal dalam menyaring dan mengeluarkan racun uremik dalam tubuh. Hemodialisis dapat menimbulkan beberapa dampak yaitu kram otot, hiperkalemia, hipotensi atau hipertensi dan anemia. Anemia yang dialami pasien PGK sebagian besar diakibatkan oleh defisiensi erythropoietin. Penilaian kesesuaian pemberian terapi anemia pada pasien PGK dengan standar yang berlaku menjadi penting untuk mencapai efek terapi yang optimal. Tujuan dari penelitian ini untuk menilai penggunaan obat anemia pada pasien PGK yang sedang menjalani hemodialisis di RSU Ari Canti pada periode Januari-Desember 2020. Penelitian ini termasuk penelitian deskriptif dengan data diambil menggunakan teknik restrospektif yang melibatkan 80 sampel data rekam medis, yang dipilih secara purposive sampling. Pada penelitian ini menunjukan hasil pola pemakaian obat anemia pada pasien PGK yang sedang melakukan hemodialisis mendapat pengobatan tunggal (73,75%) dan pengobatan kombinansi (26,25%). Obat yang dipakai ialah erythropoietin alfa, iron dan asam folat. Penilaian penggunaan obat anemia pada pasien PGK yang melakukan hemodialisis atas dasar ketepatan pasien (100%), ketepatan indikasi (100%), ketepatan obat (97,5%), ketepatan dosis (100%), ketepatan interval waktu pemberian (100%) dan waspada efek samping (100%). Kesimpulannya penilaian penggunaan obat anemia pada pasien PGK yang sedang melakukan hemodialisis di RSU Ari Canti pada tahun 2020 telah memenuhi kriteria ketepatan pasien, ketepatan indikasi, ketepatan dosis, ketepatan obat, ketepatan interval waktu minum obat dan kewaspadaan terhadap efek samping.
Perbandingan Efektivitas Aromaterapi Lavender dan Aromaterapi Rosemary terhadap Stres pada Dewasa Ni Made Maharianingsih; Ni Made W. Ariasanti
Indonesian Journal of Clinical Pharmacy Vol 11, No 1 (2022)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/ijcp.2022.11.1.33

Abstract

Stres merupakan perubahan keadaan disebabkan oleh adanya tuntutan lebih berat. Stres terjadi pada semua usia, namun perubahan tanggung jawab pada dewasa menyebabkan usia ini rentan mengalami stres. Aromaterapi lavender dan rosemary merupakan aromaterapi yang digunakan untuk mengatasi stres. Penelitian ini bertujuan untuk membandingkan efektivitas aromaterapi lavender dan rosemary dalam mengatasi stres pada dewasa. Penelitian ini berjenis quasi exsperimental two-group pre-post test design yang dilakukan pada bulan Mei 2021. Penelitian ini melibatkan 70 subjek dewasa yang dipilih secara purposive sampling. Subjek dibagi menjadi dua kelompok, yakni kelompok intervensi aromaterapi lavender dan kelompok intervensi aromaterapi rosemary selama 7 hari. Tingkat stres diukur melalui kuesioner Depression, Anxiety, Stress Scale 42 (DASS-42). Pada kelompok pertama, rata-rata stres pada subjek penelitian sebesar 23,5 sebelum pemberian aromaterapi lavender. Kemudian setelah intervensi, terjadi penurunan stres pada hari ketiga, kelima, dan ketujuh masing-masing sebesar 8,97%, 18,90%, dan 34,14%. Pada kelompok kedua, rata-rata stres sebesar 22,14 sebelum pemberian aromaterapi rosemary, dengan penurunan stres pada hari ketiga, kelima, dan ketujuh masing-masing sebesar 12,91%, 25,36%, dan 51,14% setelah intervensi. Uji Mann-Whitney U menunjukkan penurunan tingkat stres signifikan lebih tinggi (p=0,000) setelah penggunaan aromaterapi rosemary dibandingkan lavender. Dapat disimpulkan bahwa aromaterapi rosemary memiliki efektivitas signifikan lebih tinggi (p=0,000) dalam menurunkan stres pada dewasa dibandingkan aromaterapi lavender.Kata kunci: Aromaterapi, lavender, rosemary, stres Comparison of Aromatherapy Effect of Lavender and Rosemary to Stress in AdultsAbstractStress is a change condition caused by severe demands, and it occurs at all ages, depending on responsibility as adults. Furthermore, lavender and rosemary aromatherapy can be used to alleviate the effects. Therefore, this study aimed to compare the effectiveness of lavender and rosemary aromatherapy in managing stress in adults. This was a quasi-experimental two-group pre-post test design study conducted in May 2021. A total of 70 adult subjects were selected through purposive sampling, divided into two groups: one receiving lavender and the other rosemary aromatherapy interventions for 7 days. The stress level was measured by the Depression, Anxiety, and Stress Scale 42 (DASS-42) questionnaire. The results showed average stress before the administration of lavender on the subjects from the first group to be 23.5, after which it was observed to decrease by 8.97%, 18.90%, and 34.14% on the third, fifth, and seventh day, respectively. Meanwhile, in the second group, the average stress before the given intervention of rosemary aromatherapy was 22.14, which was observed to decrease by 12.91%, 25.36%, and 51.14% on the third, fifth, and seventh day, respectively. The Mann-Whitney U test showed a higher reduction in stress levels (p=0.000) after using rosemary aromatherapy. It is concluded that rosemary aromatherapy is more effective (p=0.000) in reducing stress in adults than in lavender.Keywords: Aromatherapy, lavender, rosemary, stress
Administered of Lavender (Lavandula Angustifolia) Aromatherapy To Improve Sleep Quality for the Elderly Ni Made Maharianingsih; A.A Sagung Istri Iryaningrat; Dhiancinantyan Windidaca Brata Putri
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 3 No 2 (2020)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v3i2.17926

Abstract

Elderly people are age group with a higher incidence of disease or disorders than adults because of physical or psychological changes such as insomnia or decreased quality of sleep. Around 35 % of the total population decreased in sleep quality in the world and in Indonesia around 50%. Aromatherapy that using essential oils can be used as an alternative therapy besides drugs to treat sleep difficulties such as lavender Lavender contains linalool and linalyl acetate which can improve sleep quality and has a calming effect. The purpose of this study was to see the effect of lavender aromatherapy to improve sleep quality elderly. This research design used a pre-experimental design with one group pretest-posttest design method. Respondents were 42 elderly which taking with purposive sampling who resides in panti werda. Data analysis used a non-parametric test, namely the Wilcoxon test. The results obtained were that before using lavender aromatherapy there were 42 respondents (100%) who experienced a decrease in sleep quality. After giving lavender aromateraphy, 38 respondents (90.47%) experienced an increase in sleep quality and 4 respondents (9.53%) did not experience any changes, with p = 0.000. Improved sleep quality can be seen from the difference in the value of subjective sleep quality parameters, sleep latency, sleep duration, sleep efficiency, sleep disturbances, and daytime dysfunction based on the difference between the pretest and posttest scores. It can be concluded that giving lavender aromatherapy can improve the quality of sleep in the elderly.
Penyuluhan Penggunaan Antibiotik yang Bijak di Rumah Tangga Desa Bengkel, Tabanan I Gusti Ayu Rai Widowati; Ida Ayu Manik Partha Sutema; Ni Made Maharianingsih; Ni Putu Aryati Suryaningsih; I Gusti Ngurah Agung Windra Wartana Putra; Ketut Agus Adrianta; Ni Komang Semara Yanti; Ni Nyoman Sri Budayanti
Jurnal Pengabdian kepada Masyarakat Wahana Usada Vol. 5 No. 1 (2023): Juni: Jurnal Pengabdian kepada Masyarakat Wahana Usada
Publisher : Sekolah Tinggi Ilmu Kesehatan KESDAM IX/Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47859/wuj.v5i1.310

Abstract

Background: Using antibiotics for self-medication increases the risk of developing resistance, which raises morbidity and mortality. Communities are crucial in stopping and limiting the spread of antibiotic resistance (AMR). 80% of the residents in Bengkel Village work as farmers. The agrarian community in Bengkel Village has highly magnificent natural potential as well as agricultural and cultural activities that are still well maintained. It also has the largest “subak” land in Kediri Regency. Purpose: This community service is to educate the general population about the importance of limiting the use of antibiotic self-medication, which is essential for combating AMR. Methods: The Clinical Pharmacy Study Program, the Indonesian Pharmacists Association Bali Province, and the One Health Collaborating Center collaborated on this community service. On July 17, 2022, in Bengkel Village-Tabanan, a health counseling intervention was done with housewives who are participants in the Family Welfare Empowerment. Results: Over 50 people from the Chairman, Management, and Family Welfare Empowerment cadres in Bengkel Village made up the community component of this health counseling. The participants' enthusiasm for watching the event and engaging with the resource people is proof that the activity went off without a hitch. By providing more counseling, activities are intended to be sustained (stage 2). Conclusion: Community service in Bengkel Village-Tabanan is expected to provide knowledge about health and the importance of AMR awareness. For the continuation of this activity, it is recommended to conduct outreach to other community groups such as farmers, breeders, and young age groups.
GAMBARAN PENGGUNAAN COMPLEMENTARY ALTERNATIVE MEDICINE (CAM) PADA PASIEN HIPERTENSI DI WILAYAH KERJA PUSKESMAS BLAHBATUH II Ni Nyoman Ayu Devi Suyeni; I Gusti Ayu Agung Septiari; Ni Made Maharianingsih
JOURNAL SCIENTIFIC OF MANDALIKA (JSM) e-ISSN 2745-5955 | p-ISSN 2809-0543 Vol. 4 No. 9 (2023): September
Publisher : Institut Penelitian dan Pengembangan Mandalika Indonesia (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/10.36312/vol4iss9pp164-172

Abstract

Hypertension is an increase in a person's systolic blood pressure ≥ 140 mmHg and diastolic ≥ 90 mmHg. The importance of hypertension sufferers to control blood pressure to prevent cardiovascular risk, one of which is the non-pharmacological alternative of Complementary Alternative Medicine (CAM). This study aims to describe the use of CAM in hypertensive patients in the working area of ​​the Blahbatuh II Health Center. This research method is a non-experimental quantitative descriptive study with a cross-sectional method. The results of this study found that the most use of CAM for the treatment of hypertension in the working area of ​​the Blahbatuh II Health Center were women (59.6%), aged 56-65 years (51.4%), high school education (42.2%), most of them not working/household (33.9%), income ≤ Rp. 2,627,000 (39.4%), suffer from hypertension for 1-5 years (76.1%), have no family history of hypertension (56.9%), hypertension medication, namely amlodipine (52.3%), drinking schedule every day (45.9%). Respondents used CAM since diagnosis (66.1%), CAM was combined with conventional drugs (62.5%) and was recommended by the family (45.8%), the reason that using CAM was very trusting CAM (47.2%), and the reasons for not using CAM were the reasons doctors did not recommend (54.1%), felt a positive effect (94.4%) and were satisfied (94.4%) using CAM. The most common types of CAM were biological therapy in the form of herbs (56.9%), the frequency of using CAM once a day (45.8%), the types of plants used were celery and starfruit (19.5%), plant parts namely leaves (41.5%), the method of processing is boiled first (61%), with a dose of one glass (48.8%) and the use of herbal medicine is taken orally (80.5%). The conclusion of this study was that the sociodemographic characteristics of the use of CAM were mostly aged 56-65 years (51.4%), female sex (59.6%), last education SMK/SMA (42.2%), and the use of CAM was mostly used since suffering from hypertension as many (66.1%) of respondents with the most types of CAM namely biological therapy in the form of herbs (56.9%).
Sistem Pengering Daun Kelor Berbasis Internet of Things dan Artificial Intteligence I wayan Sudiarsa; Putu Sugiartawan; I Gede Iwan Sudipa; Ni Made Maharianingsih; I Kadek Adiana Putra
IJEIS (Indonesian Journal of Electronics and Instrumentation Systems) Vol 13, No 2 (2023): October
Publisher : IndoCEISS in colaboration with Universitas Gadjah Mada, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijeis.89823

Abstract

Drying Moringa leaves is needed to reduce the water content so that the Moringa leaves become fresh and can be used for the following process. Drying Moringa leaves to change the water content from 80% to 9.2% requires ideal heating conditions because the heating speed must not damage the nutritional content in the leaves. Developing an existing drying system using IoT to monitor humidity and temperature to increase the drought stability of the Moringa leaves produced. By using IoT, it is hoped that drying conditions can be watched from anywhere and recorded so that if undesirable things happen, it will be easier to track the history of the drying process that has taken place. This system is also connected to a recommendation system using an Artificial Neural Network (ANN). This system will provide recommendations for the best conditions for Moringa flour production because various external factors influence the drying of Moringa leaves. Utilization of the ANN model can recognize data patterns in seasonal time series. The results of implementing the Moringa leaf drying machine can reduce the time by 120 minutes faster than the previous tool