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EFEK ANALGESIK KOMBINASI EKSTRAK HERBA TAPAK LIMAN (Elephantopus scaber L) DAN RUMPUT MUTIARA (Hedyotis corymbosa L) PADA MENCIT JANTAN DENGAN METODE PODODOLORIMETRI Sutema, Ida Ayu Manik Partha
Jurnal Ilmiah Medicamento Vol 3 No 2 (2017): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v3i2.1036

Abstract

Pada penelitian ini telah dilakukan uji efek analgesik dari bahan alam kombinasi Ekstrak Tapak Liman (Elephantopus scaber L) dan Rumput Mutiara (Hedyotis corymbosa L) dimana sebagai hewan coba digunakan mencit putih jantan (Mus Muscullus) yang diinduksi dengan pemberian stimulus elektrik pada bagian telapak kaki mencit. Mencit putih jantan sebagai hewan uji dibagi menjadi 4 kelompok : kelompok uji I diberi larutan kombinasi tapak liman dan rumput mutiara konsentrasi 0,13% b/v dengan dosis 52 mg/kg BB, kelompok uji II konsentrasi 0,39% b/v dengan dosis 156 mg/kg BB, kelompok pembanding diberi larutan asetosal dengan dosis 80mg/kg BB, dan kelompok kontrol diberi aquadem dengan volume pemberian 20 ml/kg BB per oral. Parameter yang diamati berupa lamanya waktu (detik) respon tangisan atau jeritan dari mencit putih jantan selama dialiri arus 15 volt setiap 10 menit sebagai respon nyeri akibat stimulus nyeri yang diberikan oleh alat Pododolorimetri. Berdasarkan analisis data secara statistik disimpulkan larutan ekstrak kombinasi Tapak Liman dan Rumput Mutiara yang diberikan pada mencit (Mus Muscullus) dengan dosis 52 mg/kg BB dan 156 mg/kg BB memiliki efek analgesik. Pada larutan kombinasi Ekstrak Herba Tapak Liman dan Rumput Mutiara yang diberikan dengan dosis 156 mg/kg BB memiliki aktivitas yang sebanding dengan Asetosal yang diberikan dengan dosis 80 mg/kg BB.
THE EFFECT OF LAVENDER AROMATHERAPY ON DYSMENORRHOEA STUDENTS IN INSTITUTE OF HEALTH SCIENCE MEDICA PERSADA BALI AA Sg Dewi Pradnya Pramita; IA Manik Partha Sutema; Dhiancinantyan Windydaca Brata Putri
Journal Pharmaceutical Science and Application Vol 2 No 1 (2020): Journal Pharmaceutical Science and Application
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (420.323 KB) | DOI: 10.24843/JPSA.2020.v02.i01.p02

Abstract

Background: Menstrual pain (dysmenorrhoea) is a symptom characterized by discomfort in the abdomen during menstruation. Lavender aromatherapy is beginning to be sought as one of the non-pharmacological therapies because the use of NSAIDs is reported to cause many side effects. The main components of lavender, linalool (35%) and linalyl acetate (51%) are efficacious as analgesics and maximally absorbed through the skin. Objective: This study aims to determine the effect of lavender aromatherapy on the menstrual pain of female college students at the Persada Medika Institute of Bali. Methods: Quasy experimental with one group pre-posttest design. The study was followed by 38 female students with moderate to severe pain using the random sampling technique. Data were analyzed using the non-parametric Wilcoxon test with p <0.05. Results: The results prior to lavender aromatherapy showed moderate pain at 73.7% and severe pain 26.3%. After lavender aromatherapy was administered, they showed moderate pain at 21% and mild pain at 79%. The Wilcoxon test indicated that the value of p = 0,000, where p <0.05. Conclusion: There is an effect of lavender aromatherapy to decrease menstrual pain (dysmenorrhoea) of female college students at the Persada Bali Institute of Health Sciences. Keywords: Aromatherapy Lavender, Dysmenorrhoea, Pain Scale, Linalool, Linalyl Acetate
SIDE EFFECTS PROFILE OF ANTIPLATELET MEDICATION IN PATIENTS WITH CORONARY HEART DISEASE AT BHAYANGKARA HOSPITAL BALI-INDONESIA Anak Agung Indah Astrijayanti; Made Krisna Adi Jaya; Ida Ayu Manik Partha Sutema; Ni Putu Wulanda Evayanti; Ni Ketut Tria Purnamisari
Journal Pharmaceutical Science and Application Vol 2 No 2 (2020): Journal Pharmaceutical Science and Application
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2020.v02.i02.p02

Abstract

Introduction: Coronary heart disease (CHD) is a disorder of heart function due to a lack of blood in the heart muscle due to narrowing of the coronary arteries. Antiplatelet in patients with CHD is a therapy that must be obtained by patients throughout their lives to prevent recurrent attacks and deaths from CHD. In the Province of Bali, especially in Denpasar, there is a lack of information about the type of side effects that occur on antiplatelet medication, so it is necessary to do a related study. Objective: The aim of this study is to identify the type of side effects that occur on antiplatelet medication in patients with CHD. Methods: A cross-sectional study involving 97 patients was done by observed the CHD patients treated with antiplatelet medication. Side effects were evaluate using Naranjo Algorithm. Patients were divided into three groups, including a low dose aspirin user group, clopidogrel user group, and aspirin-clopidogrel combination user group. Results: Antiplatelet side effects that occur in patients include headache (2.06%), diarrhea (1.03%), cyanosis (1.03%), gastrointestinal bleeding (8.25%), heartburn (11.34%), and nausea (6.19%). These side effects only occurred in 31.96% of the total subjects. The incidence of aspirin side effects was significantly greater than clopidogrel as well as aspirin-clopidogrel in combination (p <0.05). Conclusion: Patients with CHD who use antiplatelet agents in the long term to be more aware of the potential side effects that will occur, especially heartburn in chronic low-dose aspirin users. Keywords: Coronary Heart Disease, Side Effects, Antiplatelet, Aspirin, Clopidogrel
PHARMACIST’S ROLE IN MEDICATION RECONCILIATION TO PREVENT THE RISK OF MEDICATION ERROR AT BALI MANDARA HOSPITAL Ida Ayu Manik Partha Sutema; IBN Maharjana
Journal Pharmaceutical Science and Application Vol 3 No 1 (2021): Journal Pharmaceutical Science and Application
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2021.v03.i01.p06

Abstract

Background: Pharmacists have an important role in implementing drug reconciliation. The implementation of drug reconciliation allows the process of identifying drug administration errors due to information gaps, which we can avoid by optimizing information as early as possible at every shift in the process of providing health services through the reconciliation process. This process is crucial, especially for groups of patients with chronic diseases who have a high risk of changing health care delivery settings. Failure to identify results in errors in administering drugs that lead to worsening clinical conditions, resulting in increased service needs and health costs. Objective: Provides information about the tendency of pharmacists who work at the UPTD Bali Mandara General Hospital to reduce drug use errors through the drug reconciliation program. Methods: Thematic analysis of structured interview results. Results: Almost all participants (6 out of 8 pharmacists) tend to be willing to be involved in the drug reconciliation process. There are three main themes of consideration that underlie the tendency of pharmacists to be willing to be involved in the drug reconciliation process, namely, related to understanding the definition, purpose, and consistency of the implementation of reconciliation. In controlling the incidence of medication errors, the biggest preventable errors through medication reconciliation are drug duplication and drug discrepancy. Conclusion: The tendency for pharmacists to be involved is good, and the tendency to control the risk of medication errors is still lacking in terms of communication and consistency in filling out by all officers. Keywords: Pharmacist’s role, drug reconciliation, risk of medication errors
PENGARUH VARIASI CARBOMER DAN GLISERIN TERHADAP KUALITAS HAND SANITIZER EKSTRAK ALOE VERA: THE EFFECT OF VARIATIONS OF CARBOMER AND GLISERIN ON THE QUALITY OF HAND SANITIZER ALOE VERA EXTRACT I Gusti Ngurah Agung Windra Wartana Putra; I Putu Gede Adi Purwa Hita; I Gusti Ayu Agung Septiari; Ida Ayu Manik Partha Sutema
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 6 No 2 (2021)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (534.66 KB) | DOI: 10.37874/ms.v6i2.310

Abstract

Kondisi pandemi COVID-19 membuat penggunaan hand sanitizer dimasyarakat menjadi meningkat. Kepraktisan merupakan salah satu alasan masyarakat lebih mengunakan sediaan antiseptik hand sanitizer dibanding membersihkan tangan dengan sabun dan air mengalir. Tingginya penggunaan hand sanitizer membuat perlu adanya inovasi produk sehingga dapat memberikan kepuasan masyarakat yang lebih maksimal. Inovasi yang sering dilakukan oleh formulator adalah inovasi formula yang terkait pembaharuan bahan bahan dalam sediaan untuk meningkatkan kualitas dari suatu produk. Dalam melakukan inovasi, perlu melewati berbagai  tahapan tahapan pengujian untuk mengetahui sifat fisika dan kimia dari sediaan sehingga didapatkan sediaan  hand sanitizer yang berkualitas. Penelitian ini merupakan tahapan pendahuluan dalam inovasi yang bertujuan untuk mengetahui pengaruh yang dominan dari formula gelling agent carbomer dan humektan gliserin terhadap sifat fisika dan kimia dari hand sanitizer gel ekstrak lidah buaya. Penelitian ini termasuk penelitian eksperimental dimana dibuat 8 formula dengan variasi gelling agent carbomer dan humektan gliserin. Kemudian dilakukan pengukuran sifat fisika dan kimia seperti viskositas, daya sebar dan pH.  Data dari hasil sifat viskositas sediaan gel menghasilkan persamaan polinomial Y = 85148.37(A) + 109.16 (B) – 32936.27 (A)(B).  Dari sifat daya sebar sediaan gel menghasilkan persamaan polinomial Y = -17.63 (A) + 6.69 (B) + 4.60 (A)(B). Dari hasil uji pH ke 8 formula, rata rata nilai pH yang didapat yaitu 6.8. Dari hasil penelitian dapat diperoleh kesimpulan yaitu komponen carbomer memberikan pengaruh yang dominan dibanding komponen gliserin terhadap kenaikan viskositas gel dengan nilai koefisien pengaruh sebesar 85.148.37 dan memberikan pengaruh negatif terhadap nilai daya sebar gel dengan nilai koefisien pengaruh sebesar -17.63.
Socialization of Osteoporosis Prevention Exercise and Covid-19 Vaccination Education I Gusti Ayu Rai Widowati; Ida Ayu Ratih Wulansari Manuaba; Ida Ayu Manik Partha Sutema
Journal of Health Community Service Vol. 2 No. 1 (2022): Journal of Health Community Service: 2022 March
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/jhcs.v2i1.2760

Abstract

Gymnastics prevention for osteoporosis is a combination of several exercises with various benefits. Exercises such as low-impact aerobics, which helps improve heart and lung fitness, weight-bearing exercise to increase bone density, resistance to increase muscle strength and bone density, as well as coordination and balance which are beneficial to reduce the risk of falls and fractures. Community Service by the Association of Indonesian Healthy Bone Citizens (PERWATUSI) of Bali Province collaborates with the Clinical Pharmacy and Physiotherapy Study Program at the University of Bali International to educate the general public. The education regarding knowledge, beliefs, and appropriate exercise practices to prevent the early occurrence of osteoporosis and efforts to improve the immunity system for the Covid 19 vaccination preference. The service method is carried out by socializing and practicing gymnastics in the field, followed by discussions and questions and answers with a resource person. During this study, approximately 50 public communities were enrolled. The activity went smoothly and was supported by outstanding attention from the participants. The implementation of community service with various parts needs to be intensified to provide benefits to improve the health status of the community.
EFEK ANALGESIK KOMBINASI EKSTRAK HERBA TAPAK LIMAN (Elephantopus scaber L) DAN RUMPUT MUTIARA (Hedyotis corymbosa L) PADA MENCIT JANTAN DENGAN METODE PODODOLORIMETRI Ida Ayu Manik Partha Sutema
Jurnal Ilmiah Medicamento Vol 3 No 2 (2017): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v3i2.1036

Abstract

Pada penelitian ini telah dilakukan uji efek analgesik dari bahan alam kombinasi Ekstrak Tapak Liman (Elephantopus scaber L) dan Rumput Mutiara (Hedyotis corymbosa L) dimana sebagai hewan coba digunakan mencit putih jantan (Mus Muscullus) yang diinduksi dengan pemberian stimulus elektrik pada bagian telapak kaki mencit. Mencit putih jantan sebagai hewan uji dibagi menjadi 4 kelompok : kelompok uji I diberi larutan kombinasi tapak liman dan rumput mutiara konsentrasi 0,13% b/v dengan dosis 52 mg/kg BB, kelompok uji II konsentrasi 0,39% b/v dengan dosis 156 mg/kg BB, kelompok pembanding diberi larutan asetosal dengan dosis 80mg/kg BB, dan kelompok kontrol diberi aquadem dengan volume pemberian 20 ml/kg BB per oral. Parameter yang diamati berupa lamanya waktu (detik) respon tangisan atau jeritan dari mencit putih jantan selama dialiri arus 15 volt setiap 10 menit sebagai respon nyeri akibat stimulus nyeri yang diberikan oleh alat Pododolorimetri. Berdasarkan analisis data secara statistik disimpulkan larutan ekstrak kombinasi Tapak Liman dan Rumput Mutiara yang diberikan pada mencit (Mus Muscullus) dengan dosis 52 mg/kg BB dan 156 mg/kg BB memiliki efek analgesik. Pada larutan kombinasi Ekstrak Herba Tapak Liman dan Rumput Mutiara yang diberikan dengan dosis 156 mg/kg BB memiliki aktivitas yang sebanding dengan Asetosal yang diberikan dengan dosis 80 mg/kg BB.
Analysis of Factors Affecting Healing of Acute Pharyngitis Viral Patients in Puskesmas I, Klungkung-Bali Ida Ayu Manik Partha Sutema; Made Sudiari; I Gede Palguna Reganata
WMJ (Warmadewa Medical Journal) Vol 7 No 2 (2022): November 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.2.4753.60-69

Abstract

Abstract Antibiotic resistance is closely related to the inappropriate use of antibiotics, namely the indication, dose, frequency, and duration of use. Permenkes No. 5 of 2014 states that acute pharyngitis is given antibiotic therapy if it meets the diagnostic criteria using the center criteria, but this criterion is difficult to apply because doctors take longer to diagnose. Previous research at the Klungkung I Primary Health Center used diagnosis utilizing a swab test. It was found that 100% of bacterial pharyngitis patients were negative. The strategy of delaying antibiotics for 3 days can prevent antibiotic resistance, but in therapy, without antibiotics, it is important to increase the effectiveness of therapy, it is deemed necessary by the researchers to conduct a study to analyze the factors that affect the recovery of patients with acute pharyngitis, which are mainly caused by viruses. Analyzing the factors that affect the recovery of viral pharyngitis patients. The design of the cross-sectional study was through observation of the medical record data of patients who came to the Klungkung Primary Health Center I for 3 months and got diagnostic facilities using the swab test. Patients who got a negative swab test were analyzed for the factors that influenced their recovery. Anti-inflammatory variables, rest, and paracetamol significantly affected the recovery of acute pharyngitis patients (p <0.05), and the importance index in CART analysis found that paracetamol was the most influential, followed by rest, administration of vitamins, and anti-inflammatory. Antibiotics, anti-allergies, and cough medicines do not affect the recovery of patients with acute pharyngitis viral. Paracetamol has the most effect on patient recovery, followed by rest and administration of vitamins, anti-inflammatory has very little effect on the recovery in patients of acute pharyngitis viral. Keywords: acute pharyngitis, cure, CART.
THE EFFECT OF EDUCATIONAL LEAFLET USING BLOOD ADDED TABLETS ON THE KNOWLEDGE LEVEL OF PREGNANT MOTHER PATIENTS WITH ANEMIA AT PUSKESMAS 1 JEMBRANA I Gusti Ayu Diah Candra Dewi; Ida Ayu Manik Partha Sutema; I Gede Suasnawa
Journal Pharmaceutical Science and Application Vol 4 No 2 (2022): Journal Pharmaceutical Science and Application (JPSA)
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2022.v04.i02.p03

Abstract

Background: Anemia in pregnancy is a condition where the hemoglobin (Hb) level is less than 11gr/dl in women who are pregnant. Providing education through leaflets to pregnant women is expected to help prevent anemia during pregnancy. Objective: The purpose of this study was to determine the effect of providing education on the use of blood supplement knowledge on the level of knowledge of pregnant women with anemia at Puskesmas I Jembrana in 2022. Methods: The research design used in this study was a quantitative study with a pre-experimental design approach of Groups Pretest-Posttest. The sampling technique used was total sampling with 67 pregnant women with anemia. Results: The results of this study revealed that there was an effect of leaflet education on the use of blood-added tablets on the knowledge level of pregnant women with anemia at Puskesmas 1 Jembrana with a p-value of 0.000 < (0.05) and a mean difference in the pretest and posttest values ??of 5.43. Conclusion: There is a significant effect between the level of knowledge about the use of blood steadfast tablets and the incidence of anemia in pregnant women. It is hoped that the public, especially pregnant women, will pay more attention to their condition and always consult health workers regarding the use of blood-added tablets. Keywords: Anemia; Leaflet; Knowledge
THE EFFECT OF ONLINE-BASED EDUCATION ON TREATMENT ATTITUDES AND MEDICATION ADHERENCE OF TUBERCULOSIS PATIENTS AT THE DENPASAR CITY HEALTH CENTER Ni Made Andrinia Ratih Sri Indarswari; Ida Ayu Manik Partha Sutema; I Made Bakta
Journal Pharmaceutical Science and Application Vol 4 No 2 (2022): Journal Pharmaceutical Science and Application (JPSA)
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2022.v04.i02.p06

Abstract

Background: Tuberculosis is an infectious disease with a high prevalence rate in Denpasar City. Medication adherence affects increased tuberculosis cases in Denpasar City. Medication adherence in tuberculosis patients is associated with a low attitude toward treatment, so it is necessary to make efforts to improve treatment attitudes and medication adherence of tuberculosis patients by providing health education. Online-based education with Google Meet can be a solution in delivering health education with virtual face-to-face features, so education delivery becomes more effective. Objective: This study aims to determine the effect of online-based education on treatment attitudes and medication adherence of tuberculosis patients at the Denpasar City Health Center. Methods: The pre-experiment study used one group pretest-posttest design that was conducted from February until April 2022 at several public health centers in Denpasar City. The total samples of 30 tuberculosis patients accorded the inclusion criteria were taken by purposive sampling. A questionnaire was used to measure treatment attitudes, where online-based education is given a week after the pre-test and the post-test is given 2 weeks after online-based education. Pill-count method was used to measure medication adherence. Wilcoxon analysis was used to analyze research data. Results: Wilcoxon's analysis showed a significant increase in treatment attitudes and medication adherence of tuberculosis patients before and after online-based education with google meet (p<0.05). Conclusion: Online-based education with google meet provides an increase in treatment attitudes and medication adherence of tuberculosis patients at the Denpasar City Health Center. Keywords : Online-based Education; Treatment Attitudes; Medication Adherence; Tuberculosis
Co-Authors AA Sg Dewi Pradnya Pramita Alma Lystia Savitri Mahayasa Anak Agung Indah Astrijayanti Andani, Cokorda Istri Ratih Ardianta, I Putu Riska Ayu Dyahsavira Setyartini Buana, Putu Negia Suci Cahyani Desak Made Widyanthari Dewa Ayu Putu Satrya Dewi Dewa Ayu Putu Satya Dewi Dewa Ayu Putu, Satrya Dewi Dewi, D.A.P Satrya Dewi, DAP Satrya Dewi, Ni Made Ayu Candra Dhiancinantyan Windydaca Brata Putri I Gede Suasnawa I Gede Widhiantara I GUSTI AGUNG AYU SATWIKHA DEWI - I Gusti Ayu Agung Septiari I Gusti Ayu Diah Candra Dewi I Gusti Ayu Rai Widowati I Gusti Made Aman I Gusti Ngurah Agung Windra Wartana Putra I Made Bakta I Made Jawi I Putu Aris Septa Permana I Putu Gede Adi Purwa Hita I Putu Gede Adi Purwa Hita I Putu Riska Ardinata I Putu Tangkas Suwantara Ida Bagus N Maharjana IGA Ari Septiari Intan Prima Asri Ni Komang Juliani, Ni Kadek Ketut Agus Adrianta Ketut Agus Adrianta Luh Putu Widiastini Made Krisna Adi Jaya Maharianingsih, Ni Made Maharianingsih, NM Maharjana, I.B.N Manuaba, I.A Ratih Wulansari Manuaba, IA Ratih Wulansari Maseni, I Gusti Ayu Komang Putri Ni Kadek Arinda Ni Ketut Sari Mertadewi Ni Ketut Tria Purnamisari Ni Made Andrinia Ratih Sri Indarswari Ni Made Maharianingsih Ni Made Sudiari Ni Made Yunitasari Ni Nyoman Sri Budayanti Ni Putu Aryati Suryaningsih Ni Putu Aryati Suryaningsih Ni Putu Wulanda Evayanti Ni Putu Yuliana Assari Putra, IGNA Windra Wartana Putri, Kadek Sephia Adiana Putu Yudhistira Budhi Setiawan Putu Yudhistira Budisetiawan Rajdev Dhillon Ratih, Andrinia Reganata, Gde Palguna Saputra, I Wayan Agus Gede Manik Septiari, I Gusti Ayu Agung Sukmantari, Pande Ni Nuhung Suryaningsih , Ni Putu Aryati Suryaningsih, N.P Aryati Suryaningsih, NP Aryati Wartana Putra, I Gusti Ngurah Agung Windra Widowati , I Gusti Ayu Rai Widowati, I Gusti Ayu Rai - Wijayaningrum, I Dewa Ayu Indah Windidaca Brata Putri, Dhiancinantyan Wintariani, Ni Putu Wintariani, Ni Putu Aryati Yanti, Ni Komang Semara