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Journal : Nusantara Science and Technology Proceedings

Correlation of Diabetes Mellitus and Cellular Components using Fuzzy K-Partite Wa Ode Rahma Agus Udaya Manarfa; Wisnu Ananta Kusuma; Imas Sukaesih Sitanggang
Nusantara Science and Technology Proceedings 2nd Basic and Applied Science Conference (BASC) 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2509

Abstract

PPI clustering is one of the computational methods to identify proteins that affect type 2 diabetes mellitus. One of the graph-based fuzzy clustering algorithms, namely fuzzy k-partite clustering was built to solve the problem of biological network data that has more than one function and is present in more than one cluster. which may have overlapping cluster members. A previous study analyzed the mechanism of herbal medicine using the fuzzy k-partite graph clustering method, it was found that there are three groups of proteins that have the same role in overcoming type 2 DM. in the form of backbone tissue (GO-protein). The stages in this research are type 2 DM protein data, search for significant MCL clustering proteins, mining of cellular components in the Uniprot web database, adjacency matrix construction, bipartite network formation with Fuzzy k-Partite Clustering and cluster analysis. This shows that the output of using the algorithm is a network that can provide information on biological processes in type 2 DM. If the weight of the relationship between clusters is high, it can be ascertained that the value of the degree of membership in the cluster is low and there are few cluster members. Conversely, if the weight of the relationship between clusters is low, the degree of cluster membership is high and there are many cluster members. In other words, the value of the degree of membership resulting from the application of this algorithm is inversely proportional to the value of the connectivity between clusters.
Co-Authors -, Rachmawati Abdul Rahman Saleh Abdul Wakhid Aditia Yudhistira Agus Buono Agus Mulyana Agus Purwito Ahmad Khusaeri Albar, Israr Alusyanti Primawati Anak Agung Istri Sri Wiadnyani Andi Nurkholis Andita Wahyuningtyas Anna Qahhariana Annisa Annisa Annisa Annisa Annisa Awal, Elsa Elvira Aziz Kustiyo Baba Barus Badollahi Mustafa Boedi Tjahjono Bramdito, Vandam Caesariadi Despry Nur Annisa Ahmad, Despry Nur Annisa DEWI APRI ASTUTI Dhani Sulistiyo Wibowo Dini Hayati Eddy Prasetyo Nugroho Fakhri Sukma Afina Febriyanti Bifakhlina Firman Ardiansyah Hardhienata, Medria Kusuma Dewi Hari Agung Adrianto Hasibuan, Lailan Sahrina Hendra Rahmawan Hendra Rahmawan Herawan, Yoga Heru Sukoco HUSNUL KHOTIMAH I Nengah Surati Jaya Ikhsan kurniawan Irman Hermadi Ivan Maulana Putra Khairani Krisnanto, Ferdian Kurnianto, Andi Lailan Syaufina Lilis Syarifah Luki Abdullah Medria Kusuma Dewi Hardhienata Miftah Farid mufti, abdul Muhammad Abrar Istiadi Muhammad Asyhar Agmalaro Muhammad Murtadha Ramadhan Nalar Istiqomah Nia Kurniati Peggy Antonette Soplantila Pudji Muljono Purwanti , Endang Yuni Purwanti, Endang Yuni Putra, Fiqhri Mulianda Raden Fityan Hakim Raharja, Aditya Cipta Ramadhan, Jeri Rd. Zainal Frihadian Ridwan Raafi'udin Rina Trisminingsih Risa Intan Komaraasih Rizki, Yoze Safrudin, Muhammad Safrul Sakti, Harry Hardian Santoso, Angga Bayu Satyawan, Verda Emmelinda Shelvie Nidya Neyman Sobir Sobir Sonita Veronica Br Barus Sonita Veronica Br Barus Sony Hartono Wijaya Suci Indrawati Irwan Sulistyo Basuki Suradiradja, Kahfi Heryandi Suria Darma Tarigan Syarifah Aini Taihuttu, Helda Yunita Taufik Djatna Taufik Hidayat Tenda, Edwin Tiurma Lumban Gaol Toto Haryanto Trisminingsih, Rina Unik, Mitra Wa Ode Rahma Agus Udaya Manarfa Wattimena, Emanuella M C Wisnu Ananta Kusuma Wulandari WULANDARI Yenni Puspitasari Yoanda, Sely Zuliar Efendi