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All Journal JURNAL FARMASIMED (JFM) Jurnal Penelitian Farmasi dan Herbal Jurnal Pengmas Kestra (JPK)
Aminah Syarifudin
Institut Kesehatan Medistra Lubuk Pakam
Health Professions Medicine & Pharmacology Nursing Public Health

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SOLID BATH SOAP DOSAGE FORMULATIONS OF THE ETHANOL EXTRACT OF FRESH FRUIT OF MORINDA (MORINDA CITRIFOLIA L.) Yanna Rotua Sihombing; Aminah Syarifudin; Rinaldo Berutu
Jurnal Penelitian Farmasi & Herbal Vol 1 No 1 (2018): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v1i1.60

Abstract

Morinda plants grow widely throughout the Pasipic and are one of the most significant sources of traditional medicine among the Pacific island community. Morindas contain natural antioxidants for skin health and saponins in the manufacture of soap. Morindas also has potential as an antibacterial (Flavanoid). The purpose of this research is to formulate the ethanol extract of the fruit of morinda (Morinda citrifolia L.) fresh bath soap. Preparations to become solid. This research uses experimental methods. Morinda fruit is extracted by a process of maceration. Solid bath soap preparations inspection conducted this research is test the pH with a concentration of 2,5%, 3,5% and 4,5%. Ethanol extract of the fruit of morindas can be preparations soap formulations in bath with solid inspection results show pH, pH range between 8,5-10,1 show that the solid bath soaps are qualified solid bath soap. The result showed solid bath soap preparations from ethanol extract of the fruit of morinda (Morinda citrifolia L.) fresh with variations in defferent concentrations can be formulated in to a solid bath soap.
UJI IMUNOSTIMULATOR DARI KOMBINASI EKSTRAK ETANOL HERBA BINARA (ARTEMISIA VULGARIS LINN) DAN EKSTRAK ETANOL DAUN PUCUK MERAH (SYZYGIUM OLEANA) DENGAN METODE HIPERSENSITIVITAS TIPE LAMBAT PADA TIKUS Romauli Anna Teresia Marbun; Aminah Syarifuddin; Montysory Silalahi; Radika Bella Fista Ginting
Jurnal Penelitian Farmasi & Herbal Vol 1 No 2 (2019): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v1i2.66

Abstract

One of the herbs used is herbal binara (Artemisia vulgaris L) which has been studied as a potential immunomodulator with high antioxidant activity. Previous research also stated that red shoots (Syzygium oleana) were studied as potential immunomodulators with high antioxidant activity. Several other species such as Syzygium samarangense have 16 flavonoida compounds which show pharmacological immunological activity. The purpose of this study was to determine the content of secondary metabolites of ethanol extract of herbal binara (Artemisia vulgaris L.) with red shoots (Syzygium oleana) and to determine the best dose of extract from the ethanol extract of herbal binara (Artemisia vulgaris L.) with red shoots (Syzygium oleana) can reduce the volume of swelling of mouse feet. Examination of the chemical content of secondary metabolites from the ethanol extract of herbal binara (Artemisia vulgaris L.) with red shoots (Syzygium oleana) is carried out by chemical screening and characterization of simplicia and extract. The method used is the slow type hypersensitivity method. In this test the independent variable is the secondary metabolite of ethanol extract of herb binara (Artemisia vulgaris L.) with red shoots (Syzygium oleana) with four concentrations (50, 100, 200 and 400 mg / kgBB). The positive control used by Stimuno dose is 32.5 mg / kgBB.
SOSIALISASI TENTANG EVALUASI DRUG RELATED PROBLEMS (DRPS) ANTIBIOTIK PADA PASIEN PNEUMONIA RAWAT INAP ANAK RSUD DELI SERDANG Cindy Monica; Aminah Syarifuddin
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 2 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (357.804 KB) | DOI: 10.35451/jpk.v1i2.745

Abstract

Infection is the most common disease in Indonesia, so antibiotic therapy is quite high. The increase in the use of antibiotics can lead to an increase in the irrational use of antibiotics. Irrational use can increase the number of bacteria resistance to antibiotics. Drung Related Problems (DRPs) that occur in the category of under-dose drugs (4.0%), and excess drug doses (2.0%) and no DRPs (94.0%). This indicates that the pharmacist's role is important in integrating patient therapy for the occurrence of DRPs.
SOSIALISASI PEMANFAATAN EKSTRAK DAUN SAWO MANILA (Manilkara Zapota) SEBAGAI ANTIBAKTERI TERHADAP BAKTERI Streptococcus Mutans Nur Ulina M. Br. Turnip; Nia Yoseva Sirait; Aminah Syarifuddin; Novandi Purba
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 2 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (409.413 KB) | DOI: 10.35451/jpk.v1i2.899

Abstract

Daun sawo manila merupakan salah satu tanaman yang dapat digunakan sebagai obat tradisional. Daun sawo manila mengandung senyawa metabolit sekunder flavonoid, fenolik, tanin, saponin, yang bersifat sebagai antibakteri. Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri pada ekstrak daun sawo manila (Manilkara zapota) terhadap bakteri Streptoccocus mutans. Penelitian ini merupakan penelitian eksperimental laboratorium. Sampel yang digunakan diperoleh dari daun sawo diekstraksi dengan metode maserasi menggunakan pelarut etanol. Metode yang digunakan dalam uji daya hambat antibakteri menggunakan difusi cakram dengan 6 kelompok perlakuan yang terdiri dari konsentrasi 50%, 60%, 70%, 80%, serta Amoxicillin sebagai kontrol positif dan DMSO sebagai kontrol negatif diulang sebanyak 4 kali pengulangan. Parameter yang diamati adalah diameter zona hambat pertumbuhan bakteri Streptococcus mutans. Analisis data menggunakan One way-ANOVA. Hasil penelitian menunjukkan ekstrak etanol daun sawo manila memiliki kemampuan daya hambat antibakteri pada konsentrasi 50% (15,85 mm), 60% (16,45 mm), 70% (17,05 mm), 80% (17,45 mm). Kesimpulan dari penelitian ini membuktikan bahwa ekstrak etanol daun sawo manila memiliki aktivitas daya hambat antibakteri terhadap bakteri Streptococcus mutans.
Formulation and Evaluation of Nanogel from Tubifex  Worms (Tubifex  sp.) as a Future Therapeutic Agent for Burn Wounds Aminah Syarifuddin; Cucu Arum Dwi Cahya
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/p1z1pm37

Abstract

Background: Burns are one of the most common types of injuries found in the community. Burn treatment tends to be relatively expensive, which often leads to suboptimal care and prolonged healing time. Therefore, innovation in pharmaceutical formulations that are more effective, affordable, and based on natural ingredients is needed. One of the widely used dosage forms is semisolid gel, as it is practical, non-sticky, and comfortable to use. Currently, nanogel development has attracted significant attention because it can enhance the absorption of active compounds, provide more controlled drug release, and reduce toxicity. Indonesia, with its rich biodiversity, has great potential for the exploration of natural materials, including the aquatic worm Tubifex sp. Objective: This study aimed to formulate and evaluate Tubifex sp.-based nanogel as a therapeutic agent for burn wounds. Methods: The study employed an experimental method, including physical stability tests of the nanogel and in vivo tests on male white rats with controlled burn injuries. Results: The results showed that all treatment groups experienced progressive wound diameter reduction over 14 days. The negative control showed only 36.6% healing, while the positive control reached 90%. The Tubifex sp. nanogel demonstrated promising results, with formula F1 (3.75%) and F2 (7.5%) achieving 80–86.6% healing, while formula F3 (15%) reached 93.3%, even surpassing the positive control. The effectiveness of the nanogel is believed to be related to the protein, collagen, and antioxidant content in Tubifex sp., which play important roles in tissue regeneration.Conclusion: Tubifex sp. nanogel has the potential to become an innovative, natural-based therapy for burn treatment in the future.
Co-Authors Cahya, Cucu Arum Dwi Cindy Monica Montysory Silalahi Nia Yoseva Sirait Novandi Purba Nur Ulina M. Br. Turnip Radika Bella Fista Ginting Rinaldo Berutu Romaulianna Theresia Marbun Yanna Rotua Sihombing