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All Journal JURNAL FARMASIMED (JFM) Jurnal Pengmas Kestra (JPK)
Suci Wulandari
Institut Kesehatan Medistra Lubuk Pakam
Health Professions Medicine & Pharmacology Nursing Public Health

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SOCIALIZATION OF RHODAMIN B DYE CONTENT IN FLAVORED DRINKS TRADED IN LUBUK PAKAM WHICH WAS ANALYZED WITH UV-VIS SPECTROPHOTOMETRY Suci Wulandari; Ajeng Putri; Siti Wahyuni; Ika Nur Saputri; Amalia Nur Rahma
JURNAL PENGMAS KESTRA (JPK) Vol. 2 No. 1 (2022): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (251.655 KB) | DOI: 10.35451/jpk.v2i1.1134

Abstract

At this time many flavored drinks are traded in the market. Flavored drinks or what are often referred to as soft drinks are the terms used to describe the types of drinks that are sold in special packaging so that they can be consumed directly without having to be processed first. At this time the dyes that are often used in processed foods or beverages are divided into natural dyes and synthetic dyes. Synthetic dyes are generally made from chemicals. Sometimes entrepreneurs who want to make big profits use non-food grade dyes to give color to food or drinks. Rhodamine B textile dye is a synthetic dye in the form of a green or reddish-purple crystalline powder at high concentrations, while at low concentrations it is light in color and belongs to the basic xanthene group. Rhodamine B is made from raw materials of meta-diethylaminophenol and phthalic anhydride. These two raw materials are not edible but are only used for dyeing textiles, paints, paper, or clothing. These substances are often misused as food coloring and cosmetics in many countries. Foods found to contain Rhodamine B included crackers (58%), shrimp paste (51%), and snacks (42%). Rhodamin B is found in confectionery, syrup, sweets, dawet, porridge, smoked fish and cendol. Red-flavoured drinks that are traded in the Lubuk Pakam area contain Rhodamine B dye.
Evaluation of the Effectiveness of Ethanol Extract of (Acalypha indica L.) Leaves as a Treatment for Gastric Ulcers in Male Rattus norvegicus Rats Suci Wulandari; Hasni Yaturramadhan Harahap; Rinanda Desela Br Tambunan; Basyariah Lubis
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/bvmsms48

Abstract

Acalypha indica L., commonly known as Indian copperleaf, is a wild medicinal plant typically found along roadsides and in gardens. Its leaves contain various bioactive compounds, including saponins, flavonoids, alkaloids, and tannins. Traditionally, the plant has been used for its anti-inflammatory, antibacterial, antifungal, and antioxidant properties, which help combat oxidative stress caused by free radicals. This study aimed to evaluate the effectiveness of ethanol extract of Acalypha indica L. leaves in treating gastric ulcers in male Wistar rats (Rattus norvegicus). This research was a true experimental study involving the extraction of Acalypha indica L. leaves using ethanol, preparation of the extract suspension, and induction of gastric ulcers in rats using aspirin at a dose of 800 mg/kg body weight (BW) administered orally. A total of 30 male Rattus norvegicus rats were divided into six groups. Three control groups is Ulcer control, Negative control, Positive control. Three treatment groups receiving ethanol extract of Acalypha indica leaves (EEAIL) at doses of: EEDAA 50 mg/kgBB, EEDAA100 mg/kg BB, EEDAA 200 mg/kgBB. Ulcer induction was carried out daily until surgical examination was performed on days 4, 9, and 14. Macroscopic observations of the stomach were conducted to assess the number of ulcers and ulcer scores. Statistical analysis was performed using one-way ANOVA, followed by Tukey’s post hoc test to determine significant differences between groups. Macroscopic examination showed that the ethanol extract of Acalypha indica leaves (EEAIL) reduced the number of gastric ulcers. Complete healing of ulcers was observed in the positive control group, as well as in the groups receiving EEAIL at 200 mg/kg BW and 100 mg/kg BW, by day 14. In contrast, the 50 mg/kg BW group and the ulcer control group showed no signs of healing by the end of the observation period. The most effective dose was 200 mg/kg BW, demonstrating the highest capacity to reduce the number of gastric ulcers.
Processing of Rice Straw (Oryza sativa) into Activated Carbon and Its Formulation in Facial Cleansing Soap Products Regina Elianda Tampubolon; Suci Wulandari; Jhon Patar Sinurat; Reh Malem Br Karo
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/cpmerg17

Abstract

Rice straw is an abundant agricultural by-product commonly used as livestock feed or burned as waste. It contains cellulose, hemicellulose, lignin, and silica, which can be processed into activated carbon capable of adsorbing impurities and excess oil from the skin. To date, the utilization of rice straw has been limited mainly to compost fertilizer and planting media. Meanwhile, facial cleansing soaps made from natural extracts, eco-friendly ingredients, and affordable materials are increasingly popular. The objective of this study was to produce activated carbon from rice straw and apply it in the formulation of a facial cleansing soap product.This research employed an experimental laboratory approach with a quantitative descriptive method to determine the effectiveness of rice straw–based activated carbon in facial soap formulations. The procedure began with the carbonization of rice straw powder, followed by characterization of the activated carbon through moisture content analysis, ash content test, and FT-IR functional group analysis. The liquid soap was formulated into three variations and evaluated for its quality through organoleptic observation, pH measurement, cleansing ability test, and oil adsorption test.The results showed that activated carbon derived from rice straw had a moisture content of 8.92%, ash content of 7.68%, and exhibited functional groups such as –OH, aliphatic C–H, aromatic C=C, aldehyde C=O, and alcohol C–O based on FT-IR analysis. The facial soap formulations containing rice straw–based activated carbon demonstrated safe pH values—F1 = 5.46, F2 = 6.04, and F3 = 6.8—and exhibited enhanced cleansing and oil-adsorbing properties, with the highest oil adsorption value reaching 86%. These findings indicate that activated carbon from rice straw can be effectively applied in the formulation of facial cleansing soap that is safe and beneficial for skin health.
Formulation and Evaluation of Bioactive Gelatin from Tilapia (Oreochromis niloticus) Scales as an Antioxidant-Based Anti-Aging Cream Herlina Herlina; Suci Wulandari; Barita Aritonang; Amelia Putri Eflynia; Lasmaryna Sirumapea
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/nnzg2676

Abstract

The increasing demand for sustainable, bioactive cosmetic ingredients has driven the use of marine by-products as alternative raw materials. Tilapia (Oreochromis niloticus) scales, an abundant aquaculture waste, are rich in collagen that can be converted into gelatin with potential dermatological applications. This study aimed to develop and evaluate bioactive gelatin derived from tilapia scales as an antioxidant-based anti-aging cream. Gelatin was extracted with 15% acetic acid and characterized by physicochemical parameters, including yield (4.6%), moisture content (12%), and ash content (2.2%), all of which met SNI standards. Antioxidant activity was determined using the DPPH method, yielding an IC₅₀ value of 139.46 ppm, indicating moderate to weak antioxidant activity. The gelatin was formulated into cream preparations at concentrations of 1%, 1.5%, and 2%, and the formulations were evaluated for stability, homogeneity, pH, spreadability, and irritation. Anti-aging efficacy was assessed using a skin analyzer, showing improvements in skin moisture and sebum balance, with the 1% formulation demonstrating optimal performance. Although the antioxidant activity was relatively low, topical application of gelatin contributed to measurable anti-aging effects. These findings highlight the potential of tilapia scale-derived gelatin as a sustainable bioactive ingredient for cosmeceutical applications.
Education and Ultilization of the Anting-Anting Plant (Acalypha indica L.) as a Herbal Gastroprotective for Gastritis Prevention in the Community Suci Wulandari; Basyariah Lubis; Aminah S.; Sunariati Sunariati
JURNAL PENGMAS KESTRA (JPK) Vol. 6 No. 1 (2026): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/7zz2bx80

Abstract

Gastritis is one of the primary health problems in Indonesia, with a high prevalence largely triggered by the uncontrolled use of non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin. Aspirin is known to induce gastric ulcers through direct irritation and the inhibition of prostaglandin production. As a preventive alternative, the anting-anting plant (Acalypha indica L.) contains phytochemicals such as flavonoids, saponins, tannins, and alkaloids, which are proven effective as gastroprotective or gastric mucosal protective agents. This community service activity aims to educate residents regarding the risks of NSAID side effects and to promote the utilization of anting-anting leaf extract to prevent gastric damage. The activity was implemented using an educational-participatory approach involving 45 respondents in the Lubuk Pakam region, consisting of health cadres, the elderly, and housewives. Evaluation was conducted by measuring knowledge levels using pre-test and post-test questionnaires, as well as a participant satisfaction survey. The results of the activity showed a sharp and measurable increase in clinical pharmacology literacy. Prior to the education, 82.2% of respondents had a poor level of knowledge regarding the side effects of aspirin. However, after the interactive counseling, 68.9% of respondents achieved a good knowledge category. Additionally, 84.4% of respondents expressed high satisfaction with the overall benefits of this community service program. This education successfully bridges laboratory research findings into the practical realm, which is expected to encourage the implementation of safer self-medication and rational therapy within the community.
Co-Authors Ajeng Putri Amalia Nur Rahma Amelia Putri Eflynia Aminah S. Aritonang, Barita Hasni Yaturramadhan Harahap Herlina H Ika Nur Saputri Lasmaryna Sirumapea Lubis, Basyariah Regina Elianda Tampubolon Reh Malem br Karo Rinanda Desela Br Tambunan Sinurat, Jhon Patar Siti Wahyuni Sunariati Sunariati