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PENGARUH PEMBERIAN EKSTRAK JINTAN HITAM (Nigella Sativa) 50% DAN 100% TERHADAP PENYEMBUHAN ULKUS TRAUMATIKUS PADA TIKUS WISTAR Ayuda Nur Sukmawati; Endah Aryati E; Rahmawati Sri P; Oediani Santoso
Jurnal Medali Vol 1, No 1 (2013): Media Dental Intelektual
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.1.1.1-5

Traumatic ulcer is the most common lesion in the oral mucosa. Nigella sativa has been known and proven for its therapeutical effects, such as antibacterial, antiinflammation, and analgesic. This study aimed to find out the effect of Nigella sativa extract 50% and 100% towards traumatic ulcer healing visually and histologically on wistar rats.This experimental research was done using post test design. There were 3 groups in this study, consisted of 2 treatment groups and 1 control group. Rats were ulcerated using scalpel on the tip of the lip with 5 mm diameter, then betadine was applied on the control group, and Nigella sativa extract 50% and 100% on the treatment groups with 12 hours interval. This treatment was done for 10 days. Ulcer then measured at day 0, 3rd , 7th, and 10th. The rats were sacrificed for histological examination.Result from traumatic ulcer measuring was analyzed statistically using Kruskal-Wallis test and continued with post-hoc Mann-Whitney. There was significant differences with p value < 0,05. Result from histology observation was tabulated according to categories and then analyzed.In conclusion, Nigella sativa extract has an effect towards traumatic ulcer healing visually and histologically.Â Keywords: Nigella sativa extract, traumatic ulcer, in vivo

Effectiveness of Guava Leaf Extract (Syzygium Aqueum) in Inhibiting The Growth of Bacteria Aggregatibacter Actinomycetemcomitans Sudrajat, Attidhira Citra Lestari; Hardhani, Puspito Ratih; Sukmawati, Ayuda Nur; Arnov, Steffi Triany; Rimawati, Noor
South East Asia Nursing Research Vol 3, No 4 (2021)
Publisher : University of Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/seanr.3.4.2021.179-184

The role of Aggregatibacter actinomycetemcomitans bacteria can lead to the occurrence of aggressive periodontitis. The bacterium infects periodontal tissue with its virulence factor. Antibacterial administration such as chlorhexidine mouthwash is one of the treatments for periodontal disease due to bacteria. Long-term use of chlorhexidine can cause irritation of the oral mucosa, burning sensation, changes in taste perception and the appearance of stains on the teeth. One alternative is to gargle the guava leaf extract water. The antibacterial effect of guava leaf extract is obtained from its chemical compounds, namely flavonoids, phenolics, alkaloids, ethanol and tannins. This research aims to know the potential of water guava leaf extract (Syzygium aqueum) in inhibiting the growth of Aggregatibacter actinomycetemcomitans bacteria. A literature review by reviewing research articles from Science Direct and Google Scholar using the keywords "Syzygium aqueum and Aggregatibacter actinomycetemcomitans". Guava leaves contain many derivatives of compounds such as flavonoids, alkaloids, tannins, saponins, and terpenoids. The content of these compounds can be used as antibacterial because they are effective in inhibiting the growth of bacteria. Water guava leaf extract (Syzygium aqueum) can inhibit the growth of Aggregatibacter actinomycetemcomitans bacteria.

CURCUMA DOMESTICA AND MORINGA OLEIFERA EXTRACT GEL AS AN ALTERNATIVE FOR GINGIVAL BRIGHTENING: A PILOT STUDY Pratiwi, Devy Anugraeni; Bilqis, Tsuraya; Fitriyani, Rahma Dwi; Dewi, Elya Mardhania Tiara; Rismawati, Nadya; Sukmawati, Ayuda Nur
Indonesian Journal of Dentistry Vol 5, No 1 (2025): February 2025
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/ijd.v5i1.16434

Background: Gingival hyperpigmentation can occur in active smokers with high frequency. The current treatment is surgical. Therefore, researchers found a new breakthrough by creating a minimally extensive treatment, namely gel preparations. Combination of turmeric (Curcuma domestica) and moringa leaf (Moringa oleifera) extract that has the potential as a tyrosinase enzyme inhibitor. The extract will be made in a gel preparation. This study aims to determine the most optimal concentration of the gel. Method: This study used an experimental method. The gel preparation was made with various concentrations of turmeric extract and moringa leaf extract, namely F1 0.1%: 2%, F2 0.5%: 4% and F3 0.9%: 6%. Followed by testing the physical and chemical properties. Chemical properties in the form of pH, physical properties in the form of organoleptic, homogeneity, adhesiveness and spreadability by measuring the diameter of TB (No Load), B50 (Load 50 g), B100 (Load 100 g) and B150 (Load 150 g). Results: The results showed that F1, F2 and F3 were homogeneous with dark brown color, distinctive smell of moringa leaves and increasingly dilute form with each additional concentration with pH (F1) 7.99, (F2) 7.71 and (F3) 7.58. The spreadability of gel preparation F1 (TB) 2.7, (B50) 2.8, (B100) 2.9, (B150) 3.1; F2 (TB) 2.8, (B50) 3.1, (B100) 3.3, (B150) 3.5 and F3 (TB) 4.2, (B50) 4.6, (B100) 4.7, (B150) 5.1 based on these observations it is known that F3 meets the criteria for spreadability at a load of 150 gr. Conclusion: Based on this study, it can be concluded that F3 gel, a combination of turmeric extract and moringa leaf extract, has the most optimal formula because it almost meets all the requirements for gel preparations.

SURGICAL GINGIVECTOMY AND GINGIVOPLASTY ON UPPER ANTERIOR TOOTH Sukmawati, Ayuda Nur; Ramadhani, Aulia Puspasari; Dewi, Hidha Rahma Sintya
Indonesian Journal of Dentistry Vol 5, No 1 (2025): February 2025
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/ijd.v5i1.16308

ABSTRACTBackground: Gingival enlargement can be treated with periodontal therapy, starting with the initial phase therapy, which includes dental health education and scaling-root planing. When the enlargement persists after the initial treatment is carried out, a surgical procedure, namely gingivectomy, is needed.Method: A 22-year-old male patient came to RSGM UNIMUS complaining that his upper front gums appeared enlarged. The patient had been aware of the complaint since the examination during the scaling procedure two weeks ago. There was no pain in the enlarged gums, but they bled when brushing his teeth. The patient wanted to get treatment for his gums. The patient denied any relevant medical history and allergies.Outcome: The gingivectomy in this patient improved the gingiva appearance and lengthened the clinical crown on the upper anterior teeth.Conclusion: Gingivectomy was proven to be an effective surgical therapy to eliminate gingival enlargement and maintain the proportional gingival appearance, especially on the anterior teeth. However, considering the complexity of the case, more extensive mouth rehabilitation is required.

Black To Pink Gel: The Antibacterial Potency Of Curcuma Domestica And Moringa Oleifera Extract Gel Against P.Gingivalis (A Pilot Study) Sukmawati, Ayuda Nur; Megawati, Ani; Pratiwi, Devy Anugraeni
Jurnal Kesehatan Gigi Vol 12, No 1 (2025): Juni 2025
Publisher : Jurusan Kesehatan Gigi, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkg.v12i1.12454

Periodontitis continues to be a debilitating problem when improperly treated. This condition is associated with certain periodontopathological bacteria, including Porphyromonas gingivalis. Chlorhexidine, while proven effective against bacteria in the oral cavity, carries unwanted side effects. Curcuma domestica and Moringa oleifera are domestic herbs that possess several therapeutic effects. This study aims to investigate the antibacterial effect of the combined two herbs in extract gel. This experimental study used three combination formulas of C. domestica: M. oleifera (0.1%:2%, 0.5%:4%, 0.9%:6%) as the test group and chlorhexidine as the positive control group. The antibacterial inhibition disc method was used to determine the antibacterial activity in each group. The statistical analysis was carried out with Kruskal-Wallis and continued with the Mann-Whitney test. In this study, extract gel combination of Curcuma domestica and Moringa oleifera at concentrations of (0.1%:2%; 0.5%:4%; 0.9%:6%) can inhibit the growth of Porphyromonas gingivalis with average inhibition zone diameters of 12.50 mm, 14.49 mm and 16.66 mm, respectively. The inhibition zone falls in the strong category. The control group showed a mean inhibition zone of 20.96, which is classified as a very strong inhibition zone. Although there was a significant p-value between the test and control groups, the results suggested the potential of the extract gel as an alternative for treating periodontitis with lesser side effects.

Penerapan “Samuri” sebagai Upaya Deteksi Lesi Rongga Mulut pada Kelompok Lansia Perokok di Desa Kledung Kabupaten Temanggung Megawati, Ani; Sukmawati, Ayuda Nur; Pratiwi, Devy Anugraeni; Firmansyah, Shofin Okta
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 9 (2025): Volume 8 No 9 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i9.21661

ABSTRAK Kanker rongga mulut merupakan salah satu jenis kanker yang sering dijumpai di dunia, dengan prevalensi yang meningkat, terutama di Indonesia. Kabupaten Temanggung, sebagai salah satu pusat produksi tembakau terbesar di Jawa Tengah, menunjukkan tingginya insiden lesi suspek kanker rongga mulut yang sering kali terabaikan oleh masyarakat. Pendekatan deteksi dini sangat diperlukan untuk menurunkan angka kejadian kanker rongga mulut yang sering terdiagnosis pada stadium lanjut. Penelitian ini bertujuan untuk meningkatkan pengetahuan dan keterampilan masyarakat Desa Kledung, Kabupaten Temanggung, terutama bagi lansia yang memiliki kebiasaan merokok atau mengunyah tembakau, mengenai deteksi dini kanker rongga mulut melalui metode SAMURI (Periksa Mulut Sendiri). Metode pengabdian masyarakat yang dilakukan mencakup sosialisasi, edukasi, dan penerapan metode SAMURI kepada 15 peserta lansia yang berpartisipasi. Hasil evaluasi menunjukkan peningkatan signifikan dalam pengetahuan peserta tentang bahaya merokok terhadap kesehatan rongga mulut, serta kemampuan mereka dalam melakukan deteksi mandiri dengan SAMURI. Penggunaan media edukasi seperti poster dan buku saku juga terbukti efektif dalam memperkuat pemahaman peserta. Program ini diharapkan dapat menjadi model untuk pencegahan dini lesi rongga mulut di komunitas lain, khususnya di kalangan lansia yang berisiko tinggi akibat kebiasaan merokok. Kata Kunci: SAMURI, Lansia, Merokok, Kanker Mulut, Lesi Rongga Mulut ABSTRACT Oral cavity cancer is a type of cancer commonly encountered worldwide, with increasing prevalence, especially in Indonesia. Temanggung Regency, as one of the largest tobacco-producing centers in Central Java, shows a high incidence of suspected oral cavity lesions that are often overlooked by the community. Early detection approaches are necessary to reduce the incidence of oral cavity cancer, which is frequently diagnosed at advanced stages. This study aims to enhance the knowledge and skills of the community in Kledung Village, Temanggung Regency, especially among elderly individuals with smoking or tobacco-chewing habits, regarding early detection of oral cavity cancer through the SAMURI method. The community service approach implemented includes socialization, education, and application of the SAMURI method to 15 elderly participants. Evaluation results showed a significant increase in participants' knowledge about the dangers of smoking on oral cavity health, as well as their ability to conduct self-examination using SAMURI. The use of educational media such as posters and pocket books was also proven effective in reinforcing the participants' understanding. This program is expected to serve as a model for early prevention of oral cavity lesions in other communities, particularly among elderly individuals at high risk due to smoking habits. Keywords: SAMURI, Elderly, Smoking, Oral Cancer, Oral Lesion

SURGICAL GINGIVECTOMY AND SUPERNUMERARY TOOTH EXTRACTION ON PATIENT WITH FIXED ORTHODONTIC APPLIANCE: A CASE REPORT Nydia, Fidela Matta; Listy Putri, Izaz Zayyan; Aji Setiya, Reza Purwa; Sukmawati, Ayuda Nur
Indonesian Journal of Dentistry Vol 5, No 2 (2025): August 2025
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/ijd.v5i2.16014

Background: Gingival enlargement is the most common characteristic of various conditions, such as inflammation, medication effects, systemic conditions like pregnancy, leukemia, and can also be caused by orthodontic treatment. There is a positive correlation between the duration of orthodontic appliance use and the incidence of gingival enlargement since it facilitates biofilm accumulation and bacterial colonization, which triggers the inflammation.Case: A 24-year-old female patient came to RSGM UNIMUS with complaints of swollen gums in the posterior maxilla and anterior mandible, causing her teeth to appear shorter. She has experienced this issue for the past five years since using fixed orthodontic appliances. Intraoral examination revealed significant swelling in almost the entire gingival region of both the upper and lower jaws, along with a conical supernumerary tooth in the anterior region of the lower jaw. Physiological pigmentation was noted in the anterior gingiva of the mandible, which is showing a brownish color. Radiographs showedhorizontal bone loss at the alveolar crest in the lower jaw. Gingivectomy with scaling and root planning, extraction of the supernumerary tooth, and depigmentation were planned for this case.Outcome: Following a one-month post-operative evaluation, the treatment outcomes for the patient were promising with minimal pain reported. She noted that her confidence in her appearance has significantly improved.Conclusion: The use of fixed orthodontic appliances is correlated with gingival enlargement due to several factors. These appliances can lead to increased plaque accumulation and biofilm formation around the brackets and wires, which triggers inflammation. The mechanical irritation from the appliances can also exacerbate the condition, making it harder for patients to maintain her oral hygiene.

Pemberdayaan Pada Kader Kesehatan tentang Metode Kontrol Infeksi Simak dalam Pelayanan Kesehatan Gigi dan Mulut Sholekhah, Nur Khamilatusy; Sukmawati, Ayuda Nur; Sulistyorini, Ratna; Sugiarto, Rhima Shilki; Bilqis, Tsuraya
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 11 (2025): Volume 8 No 11 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i11.22774

ABSTRAK Masalah kesehatan gigi dan mulut di masyarakat saat ini prevalensinya masih tinggi. Untuk meningkatkan kesehatan gigi dan mulut diperlukan upaya promotif, termasuk pada kader kesehatan. Kader memiliki peran penting sebagai perpanjangan tangan pemerintah untuk dapat mejangkau masyarakat, menjadi fasilitator dan pelopor pencegahan penyakit termasuk penyakit gigi dan mulut. Program pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan kader kesehatan kelurahan Sendangmulyo terkait upaya pencegahan infeksi yang dapat terjadi selama perawatan gigi dan mulut. Dengan melibatkan kader dalam pelatihan yang mendalam, diharapkan akan tercipta kader yang lebih kompeten dan terampil dalam melakukan edukasi kepada seluruh lapisan masyarakat. Pengabdian masyarakat ini dilakukan dengan penyuluhan dan pelatihan. Metode yang digunakan dalam pengabdian masyarakat ini dengan ceramah, pelatihan, simulasi, praktik mandiri serta pengambilan data awal (pretest) dan akhir (posttest) menggunakan kuesioner. Peserta dalam kegiatan ini adalah kader kesehatan kelurahan Sendangmulyo, Kota Semarang. Dilakukan analisis deksriptif untuk mengetahui pengaruh sebelum dan sesudah. Program pengabdian masyarakat kepada kader kesehatan terbukti efektif dalam meningkatkan pengetahuan kader. Terdapat peningkatan pengethuan kader kesehatan tentang upaya pencegahan infeksi melaluio metode SIMAK dan adanya keberdayaan kader kesehatan dalam melakukan praktik mandiri deteksi dini karies gigi, radang gusi dan manifestasi HIV/AIDS di rongga mulut. Pemberdayaan memberikan penyuluhan dan pelatihan pada kader, dapat menciptakan kader yang lebih kompeten dan mampu memberikan edukasi kesehatan gigi kepada masyarakat. Sehingga prevalensi penyakit gigi dan mulut bisa menurun dan derajat kesehatan gigi masyarakat bisa menjadi lebih baik. Kata Kunci: Pemberdayaan Kesehatan, Kader Kesehatan, Kesehatan Gigi dan Mulut, Metode Kontrol Infeksi ABSTRACT Dental and oral health problems are still prevalent in society today. Promotional efforts are needed to improve dental and oral health, including among health cadres. Cadres play an important role as an extension of the government in reaching out to the community, acting as facilitators and pioneers in disease prevention, including dental and oral diseases. This community service program aims to increase the knowledge of health cadres in the Sendangmulyo sub-district regarding efforts to prevent infections that can occur during dental and oral care. By involving cadres in in-depth training, it is hoped that more competent and skilled cadres will be created to educate all levels of society. This community service was carried out through counseling and training. The methods used in this community service included lectures, training, simulations, independent practice, and initial (pre-test) and final (post-test) data collection using questionnaires. The participants in this activity were health cadres from the Sendangmulyo sub-district, Semarang City. Descriptive analysis was performed to determine the effect before and after. The community service program for health cadres proved effective in increasing the cadres' knowledge. There was an increase in the health cadres' knowledge about infection prevention efforts through the SIMAK method and the empowerment of health cadres in conducting independent practices for early detection of dental caries, gingivitis, and manifestations of HIV/AIDS in the oral cavity. Empowerment by providing counseling and training to cadres can create more competent cadres who are able to provide dental health education to the community. This can reduce the prevalence of dental and oral diseases and improve the dental health of the community. Keywords: Health Empowerment, Health Cadres, Dental and Oral Health, Infection Control Methods

Black To Pink Gel: The Antibacterial Potency Of Curcuma Domestica And Moringa Oleifera Extract Gel Against P.Gingivalis (A Pilot Study) Sukmawati, Ayuda Nur; Megawati, Ani; Pratiwi, Devy Anugraeni
Jurnal Kesehatan Gigi Vol. 12 No. 1 (2025): Juni 2025
Publisher : Jurusan Kesehatan Gigi, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkg.v12i1.12454

Periodontitis continues to be a debilitating problem when improperly treated. This condition is associated with certain periodontopathological bacteria, including Porphyromonas gingivalis. Chlorhexidine, while proven effective against bacteria in the oral cavity, carries unwanted side effects. Curcuma domestica and Moringa oleifera are domestic herbs that possess several therapeutic effects. This study aims to investigate the antibacterial effect of the combined two herbs in extract gel. This experimental study used three combination formulas of C. domestica: M. oleifera (0.1%:2%, 0.5%:4%, 0.9%:6%) as the test group and chlorhexidine as the positive control group. The antibacterial inhibition disc method was used to determine the antibacterial activity in each group. The statistical analysis was carried out with Kruskal-Wallis and continued with the Mann-Whitney test. In this study, extract gel combination of Curcuma domestica and Moringa oleifera at concentrations of (0.1%:2%; 0.5%:4%; 0.9%:6%) can inhibit the growth of Porphyromonas gingivalis with average inhibition zone diameters of 12.50 mm, 14.49 mm and 16.66 mm, respectively. The inhibition zone falls in the strong category. The control group showed a mean inhibition zone of 20.96, which is classified as a very strong inhibition zone. Although there was a significant p-value between the test and control groups, the results suggested the potential of the extract gel as an alternative for treating periodontitis with lesser side effects.

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