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All Journal e-CliniC Jurnal e-Biomedik Jurnal Bios Logos Jurnal Kesehatan Medika Saintika Medical Scope Journal (MSJ) Indonesian Journal of Public Health and Community Medicine
Jimmy Posangi
Universitas Sam Ratulangi
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Journal : e-CliniC

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Effect of Health Promotion with Audiovisual on Knowledge of the Use of Personal Protective Equipment for Covid-19 in Health Workers Christine T. Siwi; Suryadi N. N. Tatura; Jimmy Posangi
e-CliniC Vol. 10 No. 1 (2022): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v10i1.36881

Abstract

Abstract: Health workers are very risky to be infected by Covid-19 virus. The use of personal protective equipment (PPE) for Covid-19 can minimize the transmission of Covid-19. This study was aimed to determine the effect of audio-visual health promotion on knowledge of the use of Covid-19 PPE among health workers. This was a pre-experimental study waith one-grup pre test post test design. Data were analyzed univariately as well as bivariately with paired t-test. Respondents were 40 health workers at the Ratahan Health Center, Southeast Minahasa Regency. The activity was started by signing the approval for filling out questionnaires, doing the pretest, then audiovisual health promotion intervention was carried out and continued with filling out the questionnaire posttest. The results showed that before the health promotion about Covid-19 PPE, most respondents had lack of knowledge as many as 35 health workers (87.5%) and after the health promotion was carried out the knowledge of health workers was categorized as good, namely 36 health workers (90%). The paired t-test showed tat the average value of health worker knowledge before the health promotion about Covid-19 PPE was 22.48±1.5, and after the health promotion the knowledge of health workers was increased to 34.0±0.0 with a p-value of 0.0. In conclusion, the audiovisual health promotion about Covid-19 PPE increases the knowledge of health workers.Keywords: personal protective equipment (PPE); health workers; health promotion Abstrak: Tenaga kesehatan (nakes) sangat berisiko terhadap terinfeksi oleh virus Covid-19. Penggunaan alat pelindung diri (APD) Covid-19 dapat meminimalisir penularan Covid-19. Penelitian ini bertujuan untuk mengetahui pengaruh promosi kesehatan dengan audiovisual terhadap pengetahuan penggunaan APD Covid-19 pada nakes. Jenis penelitian ialah pre-eksperimental dengan one-grup pre test post test design. Analisis data menggunakan analisis univariat dan analisis bivariat dengan uji paired t-test. Responden penelitian ini sebanyak 40 nakes di Puskesmas Ratahan, Kabupaten Minahasa Tenggara. Kegiatan dimulai dengan menandatangani persetujuan pengisian kuesioner pretest kemudian dilakukan intervensi promosi kesehatan menggunakan audiovisual, dan dilanjutkan dengan pengisian kuesioner posttest. Hasil penelitian mendapatkan bahwa sebelum diberikan promosi kesehatan tentang APD Covid-19 pengetahuan nakes terbanyak berada pada kategori kurang yaitu 35 orang (87,5%) dan setelah diberikan promosi kesehatan pengetahuan nakes berada pada kategori baik yaitu 36 orang (90%). Hasil analisis bivariat dengan uji paired t-test menunjukkan nilai rerata pengetahuan nakes sebelum diberikan promosi kesehatan sebanyak 22,48±1,5 dan setelah diberikan promosi kesehatan pengetahuan nakes meningkat sebanyak 34,0±0,0 dengan nilai p=0,0. Simpulan penelitian ini ialah promosi kesehatan dengan audiovisual tentang APD Covid-19 berpengaruh dalam meningkatkan pengetahuan tenaga kesehatan.Kata kunci: alat pelindung diri (APD); tenaga kesehatan; promosi kesehatan
Pengaruh Evolocumab terhadap Pasien Dislipidemia dengan Intoleransi Statin Kristiani A. Laluyan; Edward Nangoy; Jimmy Posangi
e-CliniC Vol. 12 No. 1 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i1.45494

Abstract

Abstract: Statins, lipid-lowering drugs, are used to reduce low density lipoprotein cholesterol (LDL-C). Although statins are well tolerated by most people, their side effects e. g. myopathy and statin intolerance have impacts on dose reduction and therapy discontinuation. Evolocumab is considered in patients with statin intolerance. This study aimed to determine the effect of evolocumab on LDL-C levels in patients with dyslipidemia and statin intolerance. This was a literature review study using literature search on three databases, namely PubMed, ClinicalKey, and ScienceDirect with the keywords Dyslipidemia AND Evolocumab AND Statin Intolerance. The results obtained seven related literatures. In general, evolocumab therapy was safe and effective in reducing LDL-C levels for patients who needed drugs to lower LDL-C. Based on the literatures, inhibition of PCSK9 activity on evolocumab had an effect on reducing LDL-C levels by 50-70%. This therapy could reduce the risk of cardiovascular diseases such as the ratio of Apo B/Apo A1, triglycerides, and total cholesterol. In conclusion, evolocumab therapy is generally safe and effective in significantly reducing LDL-C. Adverse effects caused by the therapy tend to be mild. Keywords: dyslipidemia; low density lipoprotein cholesterol; statins; statin intolerance; evolocumab   Abstrak: Statin merupakan obat penurun lipid untuk menurunkan kolesterol low density lipoprotein (K-LDL) dan umumnya dapat ditoleransi dengan baik namun miopati dan efek samping lainnya serta intoleransi statin dapat mengarah ke penurunan dosis atau penghentian terapi. Pemberian evolocumab dapat dipertimbangkan pada keadaan intoleransi statin. Penelitian ini bertujuan untuk mengetahui pengaruh evolocumab terhadap kadar K-LDL pasien dengan dislipidemia dan intoleransi statin melalui suatu literature review. Pencarian literatur pada tiga database, yaitu PubMed, ClinicalKey, dan ScienceDirect dengan kata kunci Dyslipidemia AND Evolocumab AND Statin Intolerance. Hasil penelitian mendapatkan tujuh literatur untuk dikaji. Berdasarkan kajian literatur didapatkan terapi evolocumab umumnya aman dan efektif dalam menurunkan kadar K-LDL bagi pasien yang membutuhkan obat untuk penurunan kolesterol. yang telah didapat. Penghambatan aktivitas PCSK9 pada evolocumab berpengaruh dalam menurunkan kadar K-LDL sekitar 50-70%. Terapi tersebut dapat mengurangi risiko penyakit kardiovaskular seperti rasio Apo B/Apo A1, trigliserida, dan kolesterol total. Simpulan penelitian ini ialah terapi evolocumab umumnya aman dan efektif dalam menurunkan kadar K-LDL secara bermakna. Kejadian yang tidak diinginkan yang ditimbulkan oleh terapi cenderung ringan. Kata kunci: dislipidemia; kolesterol low density lipoprotein; statin; intoleransi statin; evolocumab
Co-Authors Aaltje E. Manampiring Angelina Stevany Regina Masengi Christa J. Egeten Christi Diana Mambo Christine T. Siwi Dian Augina Rintibulawan Rambulangi Edward Nangoy Elna D. S. Rante Emiliana Sastri Sumule Fatimawali Fatimawali . Gabriella O. Mokolensang Greachylia Chelzy Gustaaf Ratag Joshua Runtuwene Kristiani A. Laluyan M Fadhel Nurmidin Pontoh J. Ch. Putera Suryadi N. N. Tatura Tesalonika Rawung Trina Ekawati Tallei