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All Journal Jurnal Kedokteran Brawijaya Indonesian Journal of Rheumatology International Journal of Community Service Learning CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL CRJIM (Clinical and Research Journal in Internal Medicine) Caring : Jurnal Pengabdian Masyarakat CoMPHI Journal : Community Medicine and Public Health of Indonesia Journal
Perdana Aditya Rahman
Rheumatology And Immunology Division, Department Of Internal Medicine, University Of Brawijaya, Malang, Indonesia
Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Menurunkan Angka Kejadian dan Mencegah Kekambuhan COVID-19, Lupus, Reumatik, dan Alergi Melalui Pembentukan Desa Binaan Dewi, Elvira Sari; Wahono, Cesarius Singgih; Barlianto, Wisnu; Handono, Kusworini; Sari, Tita Luthfia; Hasanah, Dian; Rahman, Perdana Aditya; Anshory, Muhammad; Wulandari, Desy; Sari, Dewi Purnama; Endharti, Agustina Tri; Nurdiana, Nurdiana; Kalsum, Umi; Susianti, Hani; Kalim, Handono
International Journal of Community Service Learning Vol. 5 No. 1 (2021): February 2021
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (189.075 KB) | DOI: 10.23887/ijcsl.v5i1.30161

Abstract

Kurangnya pengetahuan masyarakat tentang COVID-19, lupus, reumatik, dan alergi mempengaruhi keberhasilan terapi, penurunan angka kejadian, dan pencegahan kekambuhan. Tujuan pengabdian masyarakat adalah membangun desa-desa binaan tanggap COVID-19, lupus, reumatik, dan alergi di Malang oleh Tim Kelompok Kajian Lupus, Autoimun, Reumatik, dan Alergi (LAURA) Universitas Brawijaya. Warga desa binaan diberikan penyuluhan berupa seminar awam dan pelatihan tentang pertolongan awal pada penyakit COVID-19, lupus, reumatik, dan alergi, kemudian diminta mengisi kuesioner posttest untuk mengukur pemahaman. Desa-desa binaan diberikan thermo-gun dan wastafel untuk menerapkan protokol kesehatan. Satu bulan kemudian dievaluasi adanya kejadian COVID-19, lupus, reumatik, dan alergi di desa binaan. Hasil evaluasi menunjukkan rata-rata warga desa binaan memahami 78,3% materi yang diberikan dan menerapkan protokol kesehatan sesuai yang diajarkan saat penyuluhan. Dilaporkan tidak ada kejadian COVID-19 serta kekambuhan lupus, reumatik, dan alergi dalam satu bulan terakhir kegiatan. Kesimpulan: pembangunan desa-desa binaan di Malang meningkatkan tanggap warga terhadap COVID-19, lupus, reumatik, dan alergi.
Exploring Knowledge Gaps in Systemic Lupus Erythematosus Among Pre-Clinical Students and Junior Doctors in Medical Faculty Pratama, Mirza Zaka; Rahman, Perdana Aditya; Wahono, Cesarius Singgih; Handono, Kusworini
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 6 No. 1 (2025): June
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/comphijournal.v6i1.299

Abstract

Understanding knowledge gaps is essential for developing more effective educational interventions that can bridge theory and practice. This study aimed to evaluate knowledge gaps in Systemic Lupus Erythematosus between pre-clinical students and junior doctors at a medical faculty. A cross-sectional study was conducted with 250 participants, divided equally between pre-clinical students and junior doctors (N=125 each). Variables such as gender, educational year, GPA, and study time were analyzed. Knowledge was assessed in five domains: pathophysiology, clinical manifestations, diagnosis, treatment, and complications. Linear regression analysis was used to identify factors associated with mean knowledge scores. No significant differences in gender distribution or study time (p = 0.899, p = 0.633, respectively). However, GPA scores were significantly higher among junior doctors (p < 0.001). Pre-clinical students scored higher than junior doctors in all SLE-related domains. GPA and study time were the strongest predictors of higher scores (Beta = 0.917, p < 0.001; Beta = 0.261, p < 0.001). GPA and study time significantly contributed to SLE knowledge scores, while gender and educational year did not. These findings suggest that academic performance and consistent study habits play critical roles in mastering SLE concepts among medical trainees.
Assessing Knowledge of Systemic Lupus Erythematosus Among Patients and Caregivers Insights from a Qualitative Inquiry Pratama, Mirza Zaka; Handono, Kusworini; Wahono, Cesarius Singgih; Rahman, Perdana Aditya; Wulandari, Dessy
Clinical and Research Journal in Internal Medicine Vol. 6 No. 2 (2025): Volume 6 No 2, November 2025
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2025.006.02.04

Abstract

Background: Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease requiring comprehensive patient knowledge for effective management. However, gaps in understanding and educational challenges persist among patients and caregivers. Aim: This study aimed to explore the knowledge, perceptions, and educational needs of SLE patients and their caregivers through a qualitative approach. Methods: Semi-structured interviews and focus group discussions were conducted with 15 patients and 10 caregivers from rheumatology clinics at Saiful Anwar General Hospital. Participants were selected using purposive sampling. Data were analyzed using thematic analysis, identifying key themes related to understanding of SLE, sources of information, knowledge gaps, and educational needs. Results: Participants demonstrated a basic understanding of SLE, but significant misconceptions were identified, particularly regarding the disease's multi-systemic impact. Healthcare providers were the primary source of information, though time constraints limited the depth of understanding. Patients and caregivers frequently turned to online sources, encountering challenges in identifying reliable information. Complex medical terminology and the emotional burden of SLE management were significant barriers. There was a clear preference for simplified, visual educational materials and a need for ongoing, continuous education and support. Conclusion: The study highlights persistent knowledge gaps and the need for enhanced educational strategies tailored to the needs of SLE patients and caregivers. Improving communication, providing reliable resources, and offering continuous education could significantly improve disease management and patient outcomes.
Exploring Caregiver Anxiety in the Daily Care of Systemic Lupus Erythematosus Patients: A Qualitative Study Wahono, Cesarius Singgih; Pratama, Mirza Zaka; Rahman, Perdana Aditya; Handono, Kusworini
Current Internal Medicine Research and Practice Surabaya Journal Vol. 7 No. 1 (2026): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Caregivers of patients with Systemic Lupus Erythematosus (SLE) face significant emotional and psychological challenges due to the chronic and unpredictable nature of the disease. This study aimed to explore the anxiety experienced by caregivers in their daily caregiving roles. Methods: A qualitative, phenomenological approach was used to gain insights into the lived experiences of 15 caregivers providing daily care to SLE patients. Data were collected through in-depth, semi-structured interviews, and thematic analysis was conducted to identify key themes related to caregiver anxiety. Results: Five main themes emerged: (1) Emotional Burden and Anxiety—Caregivers reported constant worry and stress due to the unpredictability of SLE; (2) Impact on Personal Life and Relationships—Caregiving responsibilities led to feelings of isolation and strained relationships; (3) Coping Mechanisms and Resilience—Caregivers utilized social support, religious practices, and routines to manage their anxiety; (4) Perceived Lack of Professional Support—Caregivers felt overlooked by healthcare providers and expressed a need for more comprehensive support services; (5) Long-Term Outlook and Future Uncertainty—Anxiety about the future and their ability to continue caregiving as they aged was a significant concern. Conclusion: The study highlights the multifaceted nature of caregiver anxiety in the context of SLE. There is a critical need for healthcare systems to provide holistic support that addresses both the emotional and practical needs of caregivers. By enhancing caregiver support, the overall well-being of both caregivers and patients can be improved.
Pathogenesis, Clinical Presentations and Diagnosis of IgG4-related Disease: AReview Rahman, Perdana Aditya
Indonesian Journal of Rheumatology Vol. 13 No. 2 (2021): VOL 13 NO 2 2021
Publisher : Indonesian Rheumatology Associantion

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/IJR.v13i2.189

Abstract

IgG4-Related Disease (IgG4RD) was identified by the International Classification ofDiseases (ICD) in 2012. Numerous diseases, including Mikulicz’s disease, Kuttner’stumor, Riedel’s thyroiditis, and Ormond’s disease, are pathologically associatedwith IgG4. Here, we present a review of the clinical presentation and pathogenesisof IgG4-associated disease. IgG4-RD term has been used to refer to a group ofdiseases involving multiple organs in which there is an abundant IgG4-positivelymphoplasmacytic infiltration, storiform fibrosis, obliterative phlebitis, and mildto moderate tissue eosinophilia, all of which show clinically as a tumefactive lesion,usually in more than one organ. IgG4 exhibits a unique property called an unstabledisulfide bond between its heavy chain, as described by Fab-arm exchange whichenables the recombination of a single IgG4 heavy chain with other IgG4 heavychains, resulting in a bispecific antibody incapable of cross-linking and thus offorming an immune complex. IgG4-RD pathomechanism that causes serum IgG4increase and tissue IgG4-plasma-cell deposition that is pathogenic, rather than theIgG4 itself. Genetic predisposition, autoimmunity, T-cell dysregulation, infection,and dysbiosis are just a few of the underlying pathomechanisms. Clinicalsymptoms are also frequently complex and may involve many organs. Confirmationof a diagnosis required a comprehensive anamnesis and examination. 
Co-Authors Abd. Rasyid Syamsuri Achmad Fauzi Agustina Tri Endharti Choirinnisa Meilia Ayu Putri Dessy Wulandari, Dessy desy wulandari Dewi Purnama Sari Dian Hasanah Elvira Sari Dewi Fajar Maulana Raharjo Handono Kalim Handono Kalim Handono Kalim Hani Susianti Kusworini Handono Kusworini Handono Mokhamad Fahmi Rizki Syaban Muhammad Anshory, Muhammad Nasir Aslam, Ahmad Bayhaqi Nora Ariyanti Nurdiana Nurdiana Nurdiana Nurdiana Prasetyaningtyas, Abigail Pratama, Mirza Zaka Ratnaningtyas, Yosefin Safarina Kharima Laitupa Sari, Tita Luthfia Solly Aryza Sudoyo, Aru Wisaksono Tri Wahyudi Iman Dantara Wahono, Cesarius Singgih Wilujeng Anggraini Wisnu Barlianto