Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal Nexus Biomedika Nexus Kedokteran Translasional Proceeding Seminar LPPM UMP Tahun 2014
Cr. Siti Utari
Program Studi D3 Hiperkes Dan Keselamatan Kerja FK, Universitas Sebelas Maret Surakarta. Jl. Ir. Sutami No. 36 A, Surakarta, Jawa Tengah 57126. Telp. (0271) 646994
Biochemistry, Genetics & Molecular Biology Education Medicine & Pharmacology

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Pengaruh Ekstrak Buah Mengkudu (Morinda citrifolia) terhadap Waktu Kematian Cacing Ascaris suum, Goeze In Vitro Deviana, Riza; Utari, Cr. Siti; Wasita, Brian
Nexus Biomedika Vol 1, No 2 (2012): Nexus Biomedika
Publisher : Nexus Biomedika

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (13.858 KB)

Abstract

Background: Mengkudu (Morinda citrifolia) has a terapeutic effect, such as antibacterial, anthelmintic and imunomodulator. This research was performed to understand the effect of Mengkudu (Morinda citrifolia) fruit extract on death time of  Ascaris suum, Goeze In Vitro. Methods: This research was performed using experimental laboratory method with post-test only controlled group design. Adult Ascaris suum, Goeze (108 worms) were divided into 9 groups. The worms treated with NaCl 0.9 % solution and Piperazine 0.4% g/ml served as negative control and positive control group consecutively. The worms treated with increasing dose of  Mengkudu fruits (Morinda citrifolia) extract (1% g/ml, 2% g/ml, 4% g/ml, 6% g/ml, 8% g/ml, 10% g/ml, and 12% g/ml) served as treatment groups. Observations were performed every half hour until the worms died. LC50 and LT50 were calculated using probit analysis. Statistic analysis was performed using Kruskal-Wallis test continued by Post hoc Test with Bonferroni correction. Results: Probit analysis showed that LC50 and LT50 of Mengkudu fruits extract were 4.94% g/ml and 703.32 minutes. Kruskall-Wallis test showed that significance difference at least in the two groups. Post Hoc Mann-Whitney with Bonferroni correction test showed that treatment had significant difference (p < 0.001) to negative control and 12% g/ml group had significant difference to positive control group. Conclusions: Mengkudu (Morinda citrifolia) fruits extract can induce Ascaris suum death with the death time faster than standard medicine. Keywords: Mengkudu (Morinda citrifolia) extract, Ascaris suum, Piperazin. 
Pengaruh Ekstrak Daun Jambu Biji (Psidium guajava, Linn) terhadap Mortalitas Ascaris suum, Goeze in vitro Meisya, Tri Adinda Gusvi; Utari, Cr. Siti; ., Darukutni
Nexus Biomedika Vol 1, No 2 (2012): Nexus Biomedika
Publisher : Nexus Biomedika

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (13.86 KB)

Abstract

Background: Guava leaves contain tannins and saponins that have been known to have anthelmintic effect. This study aimed  to determine the effect of guava leaf extract toward mortality of Ascaris suum, Goeze in vitro Methods: The study was a laboratory experimental research using the post-test only controlled group design. Subjects were adult Ascaris suum, Goeze. The sampling technique used was purposive sampling. Subjects were divided into 7 groups, each group consisting of 5 worms, replication performed 4 times. Saline solution was used in negative control group, pirantel pamoate 5 mg/ml was used in positive control group, while the treatment group used guava leaf extract concentration of 20%, 40%, 60%, 80%, and 100%. Worms were immersed in the test solution at 25 mL and was incubated at 37̊. Observations were made every 1 hour for 7 hours and counted the number of dead worms for 7 hours. Data were analyzed with Kruskal-Wallis test, followed by Mann Whitney test and probit analysis. Results: Total number of dead worms after 7 hours of observation in the negative control group was 0, guava leaf extract concentration of 20%, 40%, 60%, 80%, and 100% respectively by 4, 7, 12, 20, and 20, and in the positive control group was 20. Kruskal Wallis test results showed a significant difference, while Mann Whitney test showed some significant and unsignificant differences among those groups (p <0.05 and p> 0.05). Probit analysis showed LC50 and LC90 respectively at concentration 54.320% and 74.516%.. Conclusions: Based on this study, it can be concluded that the guava leaf extract affects mortality of Ascaris suum, Goeze in vitro, the increased concentration of extract increases the number of deaths of worms. Keywords: Guava leaves extract, Ascaris suum  
Pengaruh Ekstrak Daun Teh (Camellia sinensis, Linn. var. Assamica) terhadap Mortalitas Cacing Ascaris suum, Goeze Afiyyuddin N, Ahmad; Utari, Cr. Siti; Wijayanti, Lilik
Nexus Kedokteran Translasional Vol 2, No 1 (2013): Nexus Kedokteran Translasional
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.207 KB)

Abstract

Background: Camellia sinensis, Linn. var. Assamica leaves contain tannin that have been known to have anthelmintic effect. This study aimed  to determine the effect of Camellia sinensis, Linn. var. Assamica leaves extract toward death time of Ascaris suum, Goeze. Methods: The study was a laboratory experimental research using the post-test only controlled group design. Subjects were Ascaris suum, Goeze. The sampling technique used was purposive random sampling. Subjects were divided into 7 groups, each group using 4 worms, replication performed 5 times. Saline solution was used in negative control group, pirantel pamoate 5 mg/ml was used in positive control group, while the treatment group used Camellia sinensis, Linn. var. Assamica leaves extract concentration of 50%, 60%, 70%, 80%, and 90%. Worms immersed in the test solution at 25 ml and incubated at 37°C. Observations were made every 1 hour and counted dead times of all worms. Data were analyzed with regression linier and probit analysis. Results: Observations of total deaths mean time Ascaris suum, Goeze negative control for 48 hours, the positive control 1 hours 10 minutes, the concentration of 50%, 60%, 70%, 80%, 90% for 10 hours 24 minutes, 9 hours 12 minutes, 7 hours 12 minutes, 5 hours 12 minutes and 4 hours. Linear regression test results show that the variation of the concentration affects long worm death. Probit analysis results obtained LC50 and LT50 Camellia sinensis, Linn. var. Assamica leaves extract is 67,183% and 3 hours 46 minutes. Conclusions: Based on this study, it can be concluded that of Camellia sinensis, Linn. var. Assamica leaves extract affects mortality of Ascaris suum, Goeze, the increasing of extract concentration is inversely proportional with the death time of worms. Keywords: Camellia sinensis, Linn. var. Assamica leaves extract, Ascaris suum, Goeze. 
HUBUNGAN ANTARA UMUR DAN LAMA TINGGAL DENGAN GANGGUAN PENDENGARAN PADA MASYARAKAT YANG TERPAPAR BISING JALAN RAYA DI SURAKARTA Ada, Yeremia Rante; Sumardiyono, Sumardiyono; Utari, Cr. Siti
Proceeding Seminar LPPM UMP 2015: Buku III Bidang Ilmu Kesehatan dan Sains Teknik, Proceeding Seminar Nasional LPPM 2015, 26 Se
Publisher : Proceeding Seminar LPPM UMP

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kebisingan adalah suara yang tidak dikehendaki. Tiga faktor penyebab gangguan pendengaran karena bising adalah frekuensi, intensitas, dan waktu. Frekuensi bising berhubungan dengan tinggi rendahnya nada suara, intensitas berhubungan dengan kerasnya suara, sedangkan waktu berhubungan dengan lamanya paparan. Efek bising juga dipengaruhi oleh usia, kesehatan umum, jarak dengan sumber bising, dan jenis bising. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh kebisingan terhadap masyarakat yang bertempat tinggal di sekitar jalan raya di Surakarta. Penelitian ini menggunakan jenis observasional analitik dengan pendekatan cross sectional. Populasi penelitian adalah penduduk sekitar jalan raya dengan intensitas bising 65-73 dB di wilayah Surakarta Jawa Tengah. Sampel diambil melalui quota sampling berjumlah 55 orang. Hasil penelitian menunjukkan bahwa: 1) Ada hubungan antara umur dengan tingkat ketulian telinga kanan (p=0,046), telinga kiri (p=0,042), dan tingkat ketulian telinga ganda (p=0,006) pada penduduk di sekitar jalan raya, 2) Tidak ada hubungan signifikan antara lama tinggal dengan tingkat ketulian telinga kanan (p = 0,532), dengan telinga kiri (p = 0,335) maupun tingkat ketulian telinga ganda (p = 0,301) pada penduduk di sekitar jalan raya.  Kesimpulan dari penelitian ini, faktor umur memiliki hubungan dengan gangguan pendengaran masyarakat sekitar jalan raya, sedangkan lama tinggal tidak berpengaruh pada  gangguan pendengaran  masyarakat sekitar jalan raya.Kata kunci: Gangguan Pendengaran, Kebisingan, Lama Tinggal, Umur
Co-Authors Ahmad Afiyyuddin N Brian Wasita Darukutni . Lilik Wijayanti Riza Deviana Sumardiyono Sumardiyono Tri Adinda Gusvi Meisya Yeremia Rante Ada