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All Journal Jurnal Ilmiah Berkala: Sains dan Terapan Kimia Bohr: Jurnal Cendekia Kimia
Sari Namarito Simarmata
Universitas Palangka Raya
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry

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Design of Vaccine Candidate Based on Ebola Virus Epitop With In Silico Approach Erwin Prasetya Toepak; Sari Namarito Simarmata; Sudarman Rahman; Stevin Carolius Angga
Jurnal Sains dan Terapan Kimia Vol 16, No 1 (2022)
Publisher : Program Studi Kimia, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (720.028 KB) | DOI: 10.20527/jstk.v16i1.12167

Abstract

ABSTRACT          The World Health Organization (WHO) recorded as many as 2,299 cases of death with a case percentage of 66% during 2018 to 2020 in the Democratic Republic of the Congo due to the Ebola virus. Ebola virus is a member of the Filoviridae family. One of the viro cores consists of glycoprotein (GP). Messenger RNA (mRNA) generates long GP chains for the attachment protein (GP 1) and the fusion protein (GP 2). Epitope-based vaccines are a promising approach because epitopes represent immunogenic regions that elicit immunity specifically. Epitope prediction was performed based on the GP EBOV sequence available in the Data Bank. The designed vaccine could be one of the candidates for the Ebola virus vaccine. The design of the virus with access to NCBI AAB81004 was carried out by testing such as B cell epitope, T cell, and their antigenicity using the VaxiJen v2.0 server and IEDB. The T cell epitope prediction results showed that 20 T cell epitopes interacted with the Major Histocompatibility Complex (MHC) with the highest score of 2.8069. B cell epitope by linear BepiPred assay had 77 candidate epitope peptides from sequence 401-477. Karplus and Schulz's flexibility predictions showed a predictive value of 1.119 with a threshold of 1.008, with the analyzed area having an antigenic tendency where the threshold area was yellow. Keywords: Ebolavirus; Vaccine; Epitope B Cell; Epitope T Cell; In Silico
A Review: Structure and Synthesis of Perovskite as Lithium-Ion Battery (LIB) Material Miranti Maya Sylvani; Ferry Purwanto; Jumiati; Elfrida Roulina Simanjuntak; Sari Namarito Simarmata; Rendy Muhamad Iqbal; Riandy Putra; Rokiy Alfanaar; Siti Unvaresi Misonia Beladona
Bohr: Jurnal Cendekia Kimia Vol 2 No 01 (2023): Bohr: Jurnal Cendekia Kimia Vol 02 No 01
Publisher : Program Studi Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Palangka Raya

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Abstract

Lithium-ion battery (Li-ion battery or LIB) has gained significant attention as a highly promising power source. It offers excellent energy and power density profiles, along with other desirable properties such as no memory effect and long-lasting power capabilities. This has made Li-ion battery technology highly sought after in the energy industry and electronic devices. Perovskite materials have emerged as one of the non-precious metal-based materials that have attracted considerable interest in recent decades. Perovskites are highly regarded due to their remarkable properties and their potential applications in electrochemical energy devices. They possess excellent physical and chemical characteristics that make them suitable for use as electrode materials in rechargeable lithium-ion batteries.
Co-Authors Alfanaar, Rokiy Elfrida Roulina Simanjuntak Erwin Prasetya Toepak Ferry Purwanto Iqbal, Rendy Muhamad Jumiati Miranti Maya Sylvani Rahman, Sudarman Riandy Putra Siti Unvaresi Misonia Beladona Stevin Carolius Angga