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All Journal Indonesian Journal of Chemistry Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat Jurnal Ilmiah Kanderang Tingang Eduproxima : Jurnal Ilmiah Pendidikan IPA Journal SAGO Gizi dan Kesehatan BiosciED: Journal of Biological Science and Education Sasambo Journal of Pharmacy Jurnal Ilmiah Berkala: Sains dan Terapan Kimia Bohr: Jurnal Cendekia Kimia
Stevin Carolius Angga
Department Of Chemistry, University Of Palangka Raya
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Earth & Planetary Sciences Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Other

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PENCEGAHAN DEMAM BERDARAH MENGGUNAKAN LILIN ANTI NYAMUK Stevin Carolius Angga; Erwin Prasetya Toepak; Desimaria Panjaitan; Ika Oktavia Wulandari; Agus Lasono; Sari Namarito Simamarta; Sudarman Rahman
LOGISTA - Jurnal Ilmiah Pengabdian kepada Masyarakat Vol 5 No 2 (2021)
Publisher : Department of Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Andalas Kampus Limau Manis - Padang, Sumatera Barat Indonesia-25163

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/logista.5.2.82-86.2021

Abstract

Penyakit demam berdarah merupakan masalah kesehatan masyarakat di Indonesia terutama pada musim penghujan. Penyakit ini ditularkan oleh virus dengue melalui nyamuk Aedes aegypti. Provinsi Kalimantan tengah menempati urutan tiga besar dalam angka penyakit demam berdarah. Salah satu penangangan yang dapat dilakukan untuk melakukan pencegahan demam berdarah adalah dengan memanfaatkan bahan alam yaitu ekstrak dari serai (Cymbopogon citratus) atau serai wangi (Cymbopogon nardus). Pada umumnya serai digunakan sebagai bumbu dapur, sementara serai wangi tidak terlalu dimanfaatkan. Memperhatikan hal-hal tersebut, maka pembuatan lilin anti nyamuk dari ekstrak serai wangi dapat menjadi salah satu solusi dalam mengatasi penyakit demam berdarah dan pengetahuan ini patut disosialisasikan kepada masyarakat. Metode yang digunakan dalam sosialisasi ini berupa ceramah dan pembagian sampel lilin anti nyamuk. Sementara materi ceramah yang disosialisasikan adalah tentang bahaya penyakit demam berdarah, pencegahannya, pemanfaatan serai wangi sebagai alternatif pencegahan demam berdarah dalam bentuk lilin, teknik pembuatan lilin anti nyamuk. Kegiatan ini diharapkan dapat membantu pemerintah dan masyarakat desa Tumbang Nusa Kabupaten Pulang Pisau dalam penanganan penyakit demam berdarah. Selain itu, kegiatan ini diharapkan dapat meningkatkan kesadaran masyarakat tentang kesehatan dalam mencegah penyakit deman berdarah. Kata kunci: sosialisasi, demam berdarah, serai wangi, lilin anti nyamuk, minyak atsiri ABSTRACT Dengue fever disease is a public health problem in Indonesia, especially during the rainy season. This disease is transmitted by the dengue virus through Aedes aegypti mosquito. Central Kalimantan is the top three in terms of dengue fever disease. Meanwhile, there are Kalimantan natural products which can be used as repellent to prevent the mosquito, such as extracts from lemongrass (Cymbopogon citratus) or citronella grass (Cymbopogon nardus). Mostly lemongrass is used as a kitchen spice, while citronella grass is not very used generally. Furthermore, the utilization of mosquito repellent candles from citronella extract could be a solution to overcome dengue fever disesase. The method used in this socialization is in the form of lectures and distribution of mosquito repellent candle samples. While the lecture material that was socialized was about the dangers of dengue fever, its prevention, the use of citronella grass as an alternative to dengue fever prevention in the form of candles, and preparation of mosquito repellent candles. This socialization is expected to supports the government and the community of Tumbang Nusa village, Pulang Pisau Regency to overcome the dengue fever disease. In addition, this activity is expected to increase public awareness about health in preventing dengue fever. Keywords: socialization, dengue fever, citronella grass, mosquito repellent candle, essential oil
Profil fitokimia dan aktivitas antibakteri fraksi etil asetat akar jarak pagar (Jatropha curcas Linn.) Sudarman Rahman; Stevin Carolius Angga; Erwin Prasetya Toepak; Muhammad Takdir Bachtiar
Sasambo Journal of Pharmacy Vol. 2 No. 2 (2021): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (383.8 KB) | DOI: 10.29303/sjp.v2i2.116

Abstract

Bacterial infections are a major cause of chronic infections and mortality that continues to threaten public health worldwide. Various medicinal plants used in folk medicine have demonstrated wound healing and antibacterial properties. The aims of the study are investigation phytochemical and antibacterial activity of ethyl acetate fraction from jarak pagar roots (Jatropha curcas Linn.). The roots were treated with maceration method using ethanol 70% and subsequently fractioned to ethyl acetate fraction. The fractions were used for phytochemical screening and antibacterial assay using Kirby and Bauer agar difussion method. The results showed that ethyl acetate fraction jarak pagar roots contained alkaloid, flavonoids, saponins, steroids, poliphenol dan tannins. The antibacterial activity of jarak pagar roots againts Staphylococcus aureus and Escherichia coli shows that the activity of this fraction with concentration 8 mg/mL has strong inhibitory potency against the growth S. aureus with inhibitory zone is 14,3 mm and has moderate inhibitory potency against E. coli with inhibitory zone is 9 mm. The increase concentrations of ethyl asetate fraction jarak pagar roots shows high inhibition diameter of bacterial growth.  
Preparation of Poly-(GMA-EDA-β-CD-co-TMPTMA) Monolith as High Performance Liquid Chromatography Chiral Stationary Phase Column Stevin Carolius Angga; Dias Septiana; Suci Amalia; Warsito Warsito; Elvina Dhiaul Iftitah; Akhmad Sabarudin
Indonesian Journal of Chemistry Vol 19, No 4 (2019)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (574.047 KB) | DOI: 10.22146/ijc.38556

Abstract

An enantiomer molecule consisted of the chiral atom has different structure conformations, which exhibit different activities as well. Yet, its separation considerably difficult since ordinary separation could not separate both molecules. One of the popular enantioseparations which are often used was using organic polymer monolithic column modified by ethylenediamine-β-cyclodextrin (EDA-β-CD) as the enantioseparations site. The aim of this research was to produce chiral stationary phase column for enantioseparations of (±)-citronellal. It was conducted by preparing monolithic column using monomer glycidyl methacrylate (GMA), trimethylolpropane trimethacrylate (TMPTMA) as crosslinker, 1-propanol, 1,4-butanediol, and water as pore-forming agents (porogens) in the presence of α,α'-azoisobutyronitrile (AIBN) as radical initiator inside polyetheretherketone (PEEK) tubing. It was then modified with EDA-β-CD synthesized from β-CD. Finally, it was installed as a high-performance liquid chromatography column. The result shows the produced chiral stationary phase column could separate (±)-citronellal at a retention time of 44.76 and 45.71 min.
Design of Vaccine Candidate Based on Ebola Virus Epitop With In Silico Approach Erwin Prasetya Toepak; Sari Namarito Simarmata; Sudarman Rahman; Stevin Carolius Angga
Jurnal Sains dan Terapan Kimia Vol 16, No 1 (2022)
Publisher : Program Studi Kimia, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (720.028 KB) | DOI: 10.20527/jstk.v16i1.12167

Abstract

ABSTRACT          The World Health Organization (WHO) recorded as many as 2,299 cases of death with a case percentage of 66% during 2018 to 2020 in the Democratic Republic of the Congo due to the Ebola virus. Ebola virus is a member of the Filoviridae family. One of the viro cores consists of glycoprotein (GP). Messenger RNA (mRNA) generates long GP chains for the attachment protein (GP 1) and the fusion protein (GP 2). Epitope-based vaccines are a promising approach because epitopes represent immunogenic regions that elicit immunity specifically. Epitope prediction was performed based on the GP EBOV sequence available in the Data Bank. The designed vaccine could be one of the candidates for the Ebola virus vaccine. The design of the virus with access to NCBI AAB81004 was carried out by testing such as B cell epitope, T cell, and their antigenicity using the VaxiJen v2.0 server and IEDB. The T cell epitope prediction results showed that 20 T cell epitopes interacted with the Major Histocompatibility Complex (MHC) with the highest score of 2.8069. B cell epitope by linear BepiPred assay had 77 candidate epitope peptides from sequence 401-477. Karplus and Schulz's flexibility predictions showed a predictive value of 1.119 with a threshold of 1.008, with the analyzed area having an antigenic tendency where the threshold area was yellow. Keywords: Ebolavirus; Vaccine; Epitope B Cell; Epitope T Cell; In Silico
Pemberdayaan Masyarakat Penambang Emas di Kalimantan Tengah melalui Inkubasi Bisnis Berbasis Pertanian dan Peternakan Terpadu Liswara Neneng; Ria Anjalani; Dewi Saraswati; Stevin Carolius Angga; Syarpin Syarpin
Jurnal Ilmiah Kanderang Tingang Vol 13 No 2 (2022): Jurnal Ilmiah Kanderang Tingang
Publisher : FKIP Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jikt.v13i2.173

Abstract

Many areas in Central Kalimantan have a lot of small-scale gold mining activities (illegal mining), involved thousands of gold miners. These gold mining activities had caused extensive damage to the landscape, both on land and in waters. This activities carried out aim to; (1) Developing an integrated form of business incubation in agriculture and animal husbandry for gold mining communities in 3 villages in Central Kalimantan; (2) Conduct socialization, training, and assistance to the gold mining community in cultivating chickens intensively, diversifying livestock production, and carrying out integrated agriculture in a sustainable manner; (3) Fostering productive business units from upstream to downstream in integrated agriculture, through the support of infrastructure, purchase of tools and materials, to find prospective market networks through the implementation of post-harvest processing and appropriate marketing strategies. These activities were carried out in 3 (three) villages, namely, Tuwung Village, Sigi Village, and Marang Sub-District, from September to December 2022. The results of the activity showed an increase in the participants' knowledge regarding the dangers of mercury pollution and alternative types of businesses that were more productive and environmentally friendly. The skills of the miners have also increased, in terms of chicken cultivation, maggot cultivation, and post-harvest processing and also marketing. This activity is also able to support the economy of gold miners, which is obtained from the sale of 4 main products, namely chicken products, magot products, agricultural commodities, and livestock manure compost. On average, 60% of miners stated that they were willing to shift their jobs from gold miners to workers in integrated agriculture and animal husbandry.
Uji aktivitas antioksidan dan sitotoksik ekstrak daun Jarak Pagar (Jatropha curcas) Sudarman Rahman; Erwin Prasetya Toepak; Stevin Carolius Angga; Ysrafil Ysrafil
Jurnal SAGO Gizi dan Kesehatan Vol 4, No 2 (2023): Juni
Publisher : Politeknik Kesehatan Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v4i2.1175

Abstract

Background: antioxidants play an important role in preventing cell damage and generating inhibition of signalling pathways of cancer, aging and various diseases. Several extracts, oils, and herbal formulations were shown to be important Antioxidant agents for preventing cell damage. Jarak Pagar (Jatropha Curcas) leaves. were a common natural Antioxidant phytochemical screening of Jatropha leaves that contained flavonoids, where flavonoids acted as antioxidants.Objectives: this study aims to determine the Antioxidant and cytotoxic activity of ethanol extract of Jatropha leaves using the DPPH and shrimp larvae method, respectively.Methods: the design in this study was quasi-experimental, using various concentrations of ethanol extract and vitamin C (comparison control) in inhibiting free radicals and each Concentration was repeated three repetitions. The research was conducted at the Laboratory of Chemistry FMIPA Palangka Raya University and Chemistry Education FKIP Halu Oleo University in 2022. The ethanol extract of Jatropha leaves weighing 60 grams was extracted using the Soxhletion method to obtain 1.667 grams of thick ethanol extract. Phytochemical characterization was further conducted by tube method, Antioxidant tests by DPPH (1,1-diphenyl-2-picrylhydrazyl) and cytotoxic test assessed by the Brine Shrimp Lethality Test (BSLT) method. The data analysis used the One Way Anova statistical test and continued with post hoc Tamhane at 95% Cl.Results: the results showed that Jatropha curcas L. leaves contained several secondary metabolites such as flavonoids, saponins, alkaloids, polyphenols and tannins. Furthermore, the Antioxidant activity test of ethanol extract of Jatropha curcas L leaves and control (vitamin C) provided IC50 of 32.83 ± 0.09 (μg/mL) and 8.78 ± 0.21 (μg/mL), respectively. Another finding found that ethanol extract of Jatropha leaves contained active compounds that were toxic to shrimp larvae with LC50 of 427 ppm. Based on the One Way Anova test, each Concentration had a significant difference in the percentage of radical scavenging (p= 0,05). The Concentration of 160 ppm is the most effective in radical scavenging.Conclusion: we concluded that the ethanol extract of Jatropha leaves showed strong Antioxidant activity and potential as an anticancer agent
Study of Microstructure and Optical Properties of Fe2O3/TiO2 Composites as Functional Materials Rendy Muhamad Iqbal; Erwin Prasetya Toepak; Dyah Ayu Pramoda Wardani; Elda Alyatikah; Stevin Carolius Angga; Luqman Hakim
Jurnal Sains dan Terapan Kimia Vol 16, No 2 (2022)
Publisher : Program Studi Kimia, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jstk.v16i2.12142

Abstract

 Semiconductors have conductivity levels between insulators and conductors which can be applied in various fields such as photocatalytic, adsorption, and Dye Sensitizer Solar Cell (DSSC). However, some semiconductors are only active under ultraviolet light, therefore to improve their utilization, modifications are made by producing a hybrid combination of two or more materials or dopping materials. This study aims to obtain a semiconductor material with a low band gap energy from the Fe2O3/TiO2 composite material. Fe2O3/TiO2 composites were synthesized by the solid-state method and characterized by XRD, SEM-EDX, and UV-Vis. The characterization using XRD showed the peak intensity of TiO2 and Fe2O3. The morphology of the material obtained using SEM-EDX showed an even distribution of particle size, as well as the distribution of Ti, Fe, and O elements. The optical properties of the composite showed strong absorbance in the UV region for higher TiO2 compositions. On the other hand, composite materials with a higher Fe2O3 composition showed stronger absorbance in the visible light region.
Pengaruh Komposisi Bahan Organik terhadap Pertumbuhan Maggot Hermetia illucens (Black Soldier Fly): The Effect of Organic Matter Composition on the Growth of Maggot Hermetia illucens (Black Soldier Fly) Liswara Neneng; Stevin Angga; Rio Eka D.P. Hartanti; Frenklin Yuda Laba; Gamaliel Gamaliel; Dicky Satriya Pratama
BiosciED: Journal of Biological Science and Education Vol. 4 No. 1 (2023): BiosciED June 2023
Publisher : FKIP, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/bed.v4i1.8158

Abstract

The Black Soldier Fly (BSF) larvae, commonly known as maggot, have gained attention as an alternative source of protein for animal feed. Nutrition is a crucial factor in the growth of BSF larvae, and different organic materials have varying nutritional contents. This study aims to investigate the effect of different types and combinations of organic materials on the growth of BSF maggot and to determine the optimal type and combination for their growth. The results of the study indicate that a combination of rice bran and fruit/vegetable waste (50:50) provides the best growth for BSF maggot with an average weight of 454 g. A combination of rice bran and tofu dregs (50:50) yields a growth rate of 447 g, and chicken manure (100%) yields a growth rate of 435 g. These findings can serve as a reference for the development of alternative maggot-based feed in the livestock industry.
Aktivitas antioksidan dan uji sitotoksik infusa daun jarak pagar (Jatropha curcas) Sudarman Rahman; Alayya Adistia Putri; Erwin Prasetya Toepak; Stevin Carolius Angga; Ysrafil Ysrafil
Sasambo Journal of Pharmacy Vol. 4 No. 2 (2023): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v4i2.232

Abstract

Antioxidants are crucial in preventing cell damage caused by oxidation from oxidants. The use of antioxidants from natural products such as Jatropha curcas leaves can counteract free radicals due to the presence of secondary metabolites. The main aims of the study were to determine the antioxidant and cytotoxic activity of the infusion of J. curcas leaves. The sample was extracted using the infusion method. A qualitative phytochemical screening was carried out using the test tube method, antioxidant assay using the DPPH method and cytotoxic using the BSLT method. The results showed that the infuse of J. curcas leaves contained secondary metabolites such as polyphenols and tannins, alkaloids, flavonoids, and saponins. In the antioxidant activity test, infuse of J. curcas leaves and vitamin C (control) the IC50 was 58.90±2.34 ppm and 8.78±0.21 ppm respectively. The infused cytotoxic test contained an active toxic compound in shrimp larvae with an LC50 of 200.28 ppm (LC50 ≤ 1000 ppm). Based on the results of the study, infuse of J. curcas leaves showed potential as an antioxidant and anticancer agent with a strong classification.
PRELIMINARY MONITORING OF WATER QUALITY AT BANTURUNG VILLAGE, BUKIT BATU DISTRICT, PALANGKA RAYA CITY Stevin Carolius Angga; Sudarman Rahman; Erwin Prasetya Toepak; Ferry Patrix
EDUPROXIMA : Jurnal Ilmiah Pendidikan IPA Vol 6, No 3 (2024)
Publisher : Universitas Bhinneka PGRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29100/.v6i3.6001

Abstract

Water is a vital necessity for human and living things in general. It is undeniable that the decline in water quality today is the result of human activities that overexploit the environment. People's lifestyles that pay less attention to environmental aspects such as throwing garbage out of place, disposing of hazardous waste, and changing the function of forest areas that can increase the potential for erosion and often cause sedimentation at the bottom of the waters have a negative impact both directly and indirectly on the natural environment, especially water sources. High rate of forest degradation and deforestation has a significant impact on changes and decreases in water quality. In this study, water quality monitoring was conducted using several parameters as an initial step to understand the condition at the Dam and Clean Water Facility in Banturung Village, Bukit Batu District, Palangka Raya City. The results obtained from the analyzed parameters include odorless, pH 5.9, turbidity 1.0 NTU, temperature 28.1 °C, color 3.63 TCU, total dissolved solids (TDS) 10.2 mg/L, nitrate (NO3-) 0.608 mg/L, nitrite (NO2-) 0.002 mg/L, iron (Fe) 0.038 mg/L, and manganese (Mn) 0.006 mg/L.
Co-Authors Agus Lasono Akhmad Sabarudin Alayya Adistia Putri Desimaria Panjaitan Dewi Saraswati Dias Septiana Dicky Satriya Pratama Elda Alyatikah Elvina Dhiaul Iftitah Erwin Prasetya Toepak Erwin Prasetya Toepak Erwin Prasetya Toepak Erwin Prasetya Toepak Erwin Prasetya Toepak Erwin Prasetya Toepak Ferry Patrix Frenklin Yuda Laba Gamaliel Gamaliel Ika Oktavia Wulandari Lilis Rosmainar Liswara Neneng Luqman Hakim Muhammad Takdir Bachtiar Nababan, Yohana M. Rahman, Sudarman Rendy Muhamad Iqbal Ria Anjalani Rio Eka D.P. Hartanti Sari Namarito Simamarta Sari Namarito Simarmata Suci Amalia Syarpin Syarpin Warsito Warsito Widya Krestina, Luqman Hakim, Dyah Ayu Pramoda Wardani, Ysrafil, Ysrafil