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Retno A. Werdhani
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Correlation of noise level exposure on the reaction time of workers at a manufacturing company in Bandung, Indonesia Herqutanto Herqutanto; Irwan Suhadi; Imron Khazim; Dewi S. Soemarko; Retno A. Werdhani
Health Science Journal of Indonesia Vol 11 No 1 (2020)
Publisher : Sekretariat Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/hsji.v11i1.2447

Abstract

Latar Belakang: Para pekerja sering kali terpaksa berhadapan dengan kebisingan tinggi ditempat kerja. Kebisingan mengganggu perhatian yang diperlukan terus-menerus dan menurunkan produktivitas kerja, oleh sebab itu pekerja yang melakukan pengamatan dan pengawasan terhadap satu proses produksi atau hasilnya, dapat membuat kesalahan akibat dari terganggunya konsentrasi dan kurang fokusnya perhatian. Pada penelitian ini dilakukan pengukuran waktu reaksi cahaya dan suara untuk menilai fokus perhatian/konsentrasi. Metode: Studi analitik dengan desain komparatif cross sectional. Penelitian ini dilakukan pada perusahaan manufaktur yang memproduksi benang nylon sintetik. Membandingkan rerata selisih waktu reaksi cahaya dan suara sebelum dan setelah bekerja dengan pajanan kebisingan pada kelompok subjek yang bekerja pada intensitas kebisingan di atas NAB (area braiding) dibandingkan dengan yang di bawah NAB (area waring), dimana sebelumnya dilakukan pengukuran intensitas tingkat kebisingan di kedua area tersebut. Hasil Penelitian: Perbedaan bermakna waktu reaksi cahaya yang melambat pada subjek yang bekerja dengan pajanan kebisingan di atas NAB sebelum dan setelah bekerja (p=0.007), namun tidak dengan waktu reaksi suara. Tidak terdapat perbedaan bermakna waktu reaksi cahaya dan suara pada subjek yang bekerja dengan pajanan kebisingan di bawah NAB sebelum dan setelah bekerja. Terdapat perbedaan bermakna rerata selisih waktu reaksi cahaya yang melambat pada subjek yang bekerja pada pajanan kebisingan di atas NAB dengan di bawah NAB, p=0,017, namun tidak bermakna terhadap rerata selisih waktu reaksi suara. Kesimpulan: Terdapat perbedaan rerata selisih waktu reaksi cahaya pada pekerja yang bekerja dengan pajanan kebisingan di atas NAB dibandingkan dengan pekerja yang bekerja dengan pajanan kebisingan di bawah NAB, sehingga tingkat intensitas kebisingan tinggi (di atas NAB) mempengaruhi waktu reaksi cahaya dan menjadi lebih lambat. Kata Kunci: waktu reaksi cahaya; waktu reaksi suara; kebisingan Abstract Background: Workers are often exposed to high noise level at their workplaces. Noise can disrupt the worker’s concentration and focus and in the end, may cause lower productivity. Thus, workers whose main job descriptions are to supervise workflow from one phase to another are prone to mistakes due to the loss of concentration and focus. In this research, we used reaction timer with light and sound stimuli to assess attention or concentration. Methods: The study was an analytical study with comparative cross sectional design, comparing a mean difference between light and sound reaction time before and after work. This research was conducted at a manufacturing company that produces synthetic nylon fibers. The subjects were divided into two groups; the workers with noise intensity above TLV (braiding’s area) and with noise intensity below TLV (waring’s area). Prior to the study, the research has measured the intensity of the noise level in the workplace area. Result: A significant difference was found in the light’s reaction time who work with noise exposure above TLV (p= 0.007) and it was found to be slower after work with the workers who are exposed to noise above TLV. There was also a significant mean difference for the light’s reaction time between the above TLV noise group and below TLV noise group (p = 0.017). There was no significant difference in sound reaction time. Conclusion: There was a significant mean difference in light reaction time for the workers who work with noise exposure above TLV compare with the workers who work in below TLV, so that high intensity of noise level is found to affect and decrease the light reaction time of the workers. Keywords: light’s reaction time, sound’s reaction time, noise.
Effect of pH and neutrophil count on the motility and persistence of spermatozoa in the vagina of candidiasis rat models Iswara, Raja AW.; Hestiantoro, Andon; Budiningsih, Yuli; Werdhani, Retno A.; Birowo, Ponco; Wuyung, Puspita E.; Afandi, Dedi
Narra J Vol. 4 No. 2 (2024): August 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i2.823

Abstract

Sexual violence is a global issue affecting individuals regardless of their relationship to the perpetrator or the setting. Microscopic examination of spermatozoa from vaginal swabs is crucial in investigating cases of sexual intercourse to determine the time of the crime. Factors such as vaginal pH and neutrophil count influence the motility and persistence of spermatozoa in the vagina, particularly in conditions like candidiasis, highlighting the need for further research in this area. This study aimed to determine the effect of pH and neutrophil count on the motility and persistence of spermatozoa in the vagina with candidiasis. An experimental study was conducted using white rats (Rattus norvegicus) of the Wistar strain, with four male rats providing spermatozoa samples and 32 female rats receiving treatment. The female rats were divided into two groups: the normal group and the candidiasis model group. In both groups, the female rats were given vaginal insemination of spermatozoa. Variables measured included pH, neutrophil count, motility, and persistence of spermatozoa in the vagina. Data were analyzed using the Mann-Whitney test, followed by the Spearman correlation test. The findings revealed that spermatozoa motility lasted up to three minutes in normal rats, whereas in the candidiasis model, it was reduced to two minutes. Additionally, spermatozoa persistence in the vagina lasted up to six days in the normal group compared to up to three days in the candidiasis model. There were significant differences in pH, neutrophil count, motility, and persistence of spermatozoa in the vagina between the normal group and the candidiasis model (all had p<0.001). There was a correlation between pH and neutrophil count with the motility and persistence of spermatozoa in the rat’s vagina (p<0.001). In conclusion, vaginal pH and neutrophil count influence the motility and persistence of spermatozoa in the vagina of candidiasis rat models.
Impact of semen insemination on the vaginal microbiome profile of candidiasis rat model: A preliminary forensic study on sexual violence evidence Iswara, Raja AFW.; Hestiantoro, Andon; Budiningsih, Yuli; Werdhani, Retno A.; Birowo, Ponco; Wuyung, Puspita E.; Fadilah, Fadilah; Afandi, Dedi
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1256

Abstract

Sexual violence, including sexual intercourse, can occur in women experiencing vaginal discharge, particularly in cases of vaginal candidiasis. In candidiasis, the vaginal microbiome undergoes changes that could serve as a diagnostic indicator or as evidence of sexual activity.  The aim of this study was to assess the effects of semen insemination on the vaginal microbiome profile of candidiasis rats and to determine its forensic investigations in cases of sexual violence.  An experimental study was carried out using Wistar strain rats (Rattus norvegicus), consisting of four male rats (for spermatozoa donors) and twenty-four female rats. The female rats were divided into four groups: normal condition (control), normal condition post-semen insemination, candidiasis rats, and candidiasis rat post-semen insemination. Vaginal microbiome profiles were examined for each group, using alpha diversity (Chao 1, Shannon, Simpson, and Faith PD indices) and beta diversity (Bray Curtis, Jaccard, Unweighted Unifrac and Weighted Unifrac indices). Data were analyzed using the Kruskal-Wallis test for alpha diversity and the PERMANOVA test for beta diversity. The vaginal microbiome profiles of normal and candidiasis rats showed no significant differences (p>0.05). In candidiasis rats, the microbiome predominantly consisted of the Eukaryota kingdom, particularly Candida albicans. Semen insemination did not significantly affect the vaginal microbiome profile of candidiasis rats in the short term (p>0.05). However, the study highlights that the presence of Eschericia-Shigella, Roseomonas, and Archaea in the vaginal microbiome post-semen insemination potentially serves as an indicator of infection or sexual activity in forensic contexts.
Co-Authors Andon Hestiantoro Dedi Afandi Dewi Sumaryani Soemarko Elida Ilyas Evi R.N. Hidayati Fadilah Fadilah, Fadilah Herqutanto Herqutanto I N. N. Murdana Imron Khazim Irwan Suhadi Iswara, Raja AFW. Iswara, Raja AW. Ponco Birowo Puspita E. Wuyung Tri J.E. Tarigan Yuli Budiningsih