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The Administration of Orange Sweet Potato (Ipomoea Batatas L.) Extract Increases Sperm Consentration, Mortility and Viability in Male Mice Exposed to Cigarette Smoke Rizqy, Lintang Laila; Nida, Nor Anisatun; Noviana, Dwi Ayu; Nasihun, Taufiqurrachman; Widayati, Eni
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 1 (2017): June 2017
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (399.622 KB) | DOI: 10.30659/sainsmed.v8i1.1624

Abstract

Introduction: Ipomoea batatas L (LIP) contains antioxidants beta-carotene, vitamin C and vitamin E. Cigarette smoke containing ROS has been proven to decrease sperm quality.Objective: this study aimed to confirm that orange sweet potato extract increases sperm consentration, motility, and viability in mice exposed to cigarette smoke.Methods: In this experimental study with post test only control group design, 30 male mice were divided into 6 groups. Normal group (Nor-G), no intervention, served as the normal control group. Negative control group (Neg-G) was only exposed to cigarette smoke. Positive control group was only treated with IPL 16mg/ml. IPL-15, IPL-16, and IPL-17 group were treated with IPL 15, 16, and 17mg/ml and exposed to cigarette smoke, respectively.Results: Post Hoc LSD analysis showed that means of sperm concentration and viability in IPL-15, IPL-16, and IPL-17 group were significantly higher compared to that of Neg-G (p < 0.05) and were lower compared to that of Nor-G and Pos-G (p < 0.05). Mann Whitney analysis indicated that the persentage of sperm motility in IPL-15, IPL-16, and IPL-17, were significant higher compared to that of Neg-G, p < 0.05. Whilst compared to that of Nor-G and Pos-G the persentage of sperm motility in IPL-15, IPL-16, and IPL-17, there was no significant differences, p > 0.05.Conclusion: treatment of IPL capable of increasing sperm concentration, motility, and viability in male mice were exposed to cigarrette smoke.
Edukasi Manfaat Air Rebusan Gambir sebagai Obat Kumur Pencegah Plak Gigi bagi Kader PKK di Kelurahan Bandardowo Semarang Sumarawati, Titiek; Chodidjah, Chodidjah; Widayati, Eni; Soraya, Anita
Indonesian Journal of Community Services Vol 6, No 2 (2024): November 2024
Publisher : LPPM Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijocs.6.2.134-139

Abstract

Karies gigi atau gigi berlubang merupakan masalah kesehatan gigi dan mulut yang paling sering ditemui pada anak sekolah. Gambir (Uncaria gambir [Roxb.]) merupakan salah satu obat tradisional yang dimanfaatkan bersama daun sirih untuk memperkuat gigi. Akan tetapi, tidak semua warga mengetahui manfaat rebusan gambir untuk kesehatan gigi. Kegiatan pengabdian kepada masyarakat (PkM) bertujuan untuk meningkatkan pengetahuan mengetahui manfaat air rebusan gambir sebagai obat kumur pencegah plak gigi bagi kader PKK di Kelurahan Bandardowo, Semarang. Edukasi berupa penyuluhan diberikan dalam bentuk presentasi dengan power point kemudian diikuti oleh tanya jawab interaktif. Kegiatan dimulai dengan pembukaan yang menjelaskan tentang tujuan umum edukasi pencegahan plak gigi. Untuk mengetahui tingkat pemahaman awal peserta sebelum edukasi dilaksanakan pre-test yang diberikan melalui kuesioner. Kegiatan PkM diikuti oleh 20 orang Ibu-Ibu kader PKK yang berusia 30-50 tahun (60%) bekerja sebagai Ibu Rumah Tangga. Pemberian edukasi berpengaruh secara signifikan (p<0.05) dalam meningkatkan pengetahuan peserta sebelum dan sesudah edukasi. Nilai rerata post-test mengalami peningkatan 2,84 poin dibandingkan dengan nilai pre-test. Edukasi bermanfaat meningkatkan rerata nilai tingkat pengetahuan peserta mengenai manfaat air rebusan gambir dalam mencegah terjadinya karies gigi, khususnya pada anak-anak.Dental caries or cavities are schoolchildren's most common dental and oral health problems. Gambir (Uncaria gambir [Roxb.]) is a traditional medicine used with betel leaves to strengthen teeth. However, not all residents know the benefits of gambier decoction for dental health. Community service activities (PkM) aim to increase knowledge about the benefits of gambier boiled water as a mouthwash to prevent dental plaque for PKK cadres in Bandardowo Village, Semarang. Education in the form of counseling is given in the form of a PowerPoint presentation followed by interactive questions and answers. The activity began with an opening explaining the general objectives of dental plaque prevention education. A pre-test was administered via a questionnaire to determine the participants' initial level of understanding before education. The PkM activity was attended by 20 PKK cadre mothers aged 30-50 years (60%) who worked as housewives. Providing education significantly effect (p<0.05) in increasing participants' knowledge before and after education. The average post-test score increased by 2.84 points compared to the pre-test. Education helps increase the average value of participants' knowledge level regarding the benefits of gambier boiled water in preventing dental caries, especially in children.
Penyuluhan bagi Kader PKK Desa Banjardowo tentang Potensi Tanaman Kemangi (Ocinum Sanctum Linn) terhadap Kesehatan Sumarawati, Titiek; Chodidjah, Chodidjah; Widayati, Eni; Soetoko, Anita Soraya
Jurnal Pengabdian Masyarakat Kedokteran Vol 3, No 1 (2024): Januari
Publisher : Fakultas Kedokteran, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/abdimasku.3.1.33-38

Abstract

Tanaman Daun Kemangi (Ociumum sanctum Linn) mengandung banyak senyawa aktif seperti golongan alkaloid, terpenoid, fenolik, saponoid, tannin dan flavonoid yang terbukti mempunyai aktivitas sitotoksik, serta memiliki kadar nilai IC50 pada sel MCF-7 sebesar 6,95 µg/ml. Selain itu juga terbukti bahwa ekstrak etanol kemangi mempunyai aktivitas antioksidan yang sangat kuat. Tujuan pengabdian masyarakat ini adalah untuk mensosialisasikan terkait dengan hasil penelitian mengenai kandungan zat aktif dalam tanaman kemangi yang mempunyai potensi terhadap Kesehatan. Kelurahan banjardowo merupakan desa binaan Fakultas kedokteran universitas islam sultan Agung sehingga lokasi ini dipilih untuk mensosialisasikan hasil penelitian tentang tanaman kemangi mengingat banyaknya manfaat bagi Kesehatan dan meningkatkan pengetahuan ibu ibu. Metode penyuluhan yang digunakan adalah Metode ceramah dan diskusi kelompok, para ibu ibu kader PKK kelurahan BanjarDowo yang mengikuti penyuluhan sebanyak 23 orang, usia 41- 60 tahun sebanyak 16 orang dan usia 25 – 40 tahun sebanyak 7 orang. Hasil analisis nilai pretest dan postest peserta menunjukan terdapat kenaikan nilai rerata peserta pada postest, yaitu 6,70±1,8, dimana sebelum kegiatan penyuluhan dimulai nilai rerata peserta hanya mencapai angka 4,78±1,9. Dari analisis statistik menunjukan adanya perbedaan yang bermakna antara nilai pretest dan postest peserta dengan nilai p=0,000. Dengan pemberian penyuluhan pada kader PKK di kelurahan Banjardowo tentang potensi tanaman kemangi terhadap Kesehatan menunjukkan hasil adanya nilai peningkatan pengetahuan peserta sebelum diberi penyuluhan dan sesudah penyuluhan.The basil leaf plant (Ociumum sanctum Linn) contains many active compounds such as alkaloids, terpenoids, phenolics, saponoids, tannins and flavonoids which have been proven to have cytotoxic activity, and have an IC50 value in MCF-7 cells of 6.95 µg/ml. Apart from that, it has also been proven that basil ethanol extract has very strong antioxidant activity. The aim of this community service is to disseminate research results regarding the content of active substances in basil plants which have potential for health. Banjardowo sub-district is a village supported by the Faculty of Medicine, Sultan Agung Islamic University, so this location was chosen to disseminate the results of research on basil plants considering the many benefits for health and increasing mothers' knowledge. The counseling method used was the lecture and group discussion method, 23 people from PKK cadres from BanjarDowo sub-district took part in the counseling, 16 people aged 41-60 years and 7 people aged 25-40 years. The results of the analysis of participants' pretest and posttest scores showed that there was an increase in the participants' average score on the posttest, namely 6.70 ± 1.8, where before the counseling activities began, the participants' average score only reached 4.78 ± 1.9. Statistical analysis shows that there is a significant difference between the participants' pretest and posttest scores with a p value = 0.000. By providing counseling to PKK cadres in the Banjardowo sub-district about the potential of basil plants for health, the results showed that there was a value in increasing participants' knowledge before being given the counseling and after the counseling.