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Antidiabetic potential of karamunting leaves ethanolic extract as a natural herb: Blood glucose levels and pancreatic islets histomorphology on diabetic rats model Ida Yuliana; Asnawati Asnawati; Maria Ulfah; Eko Suhartono
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 3, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss3.art9

Background: Karamunting leaf is a wetland herb with antioxidant compounds that bind free radicals, reduce oxidative stress, reduce insulin resistance, and prevent the development of pancreatic cell dysfunction and damage.Objective: This study aims to prove the antidiabetic potential of the karamunting leaves ethanolic extract in treating diabetes in white male rats.Methods: This study used a true experimental with a pre-test and post-test control group design. Thirty rats were divided into four groups (control: C, ethanol extract of karamunting dose of 100 mg: P1, 200 mg: P2, and 400 mg: P3). Data on fasting blood glucose levels were taken before (pre-test) and after treatment (post-test). Data on pancreatic islets histomorphological changes (size, number, constituent cells) were analysed quantitatively. Fasting blood glucose levels were analysed using paired t-test, while the histomorphological data of the pancreatic islets were analysed using ANOVA. The data were considered significant if the p-value <0.05 (95% CI).Results: Karamunting leaf ethanol extract treatment reduced fasting blood glucose levels in diabetic rats. A 200 mg/kgBW was demonstrated as the most effective dose that improves the islets and cells number compiles the pancreatic islets, potentially treating diabetes mellitus (DM).Conclusion: Karamunting leaf ethanol extract potential as a natural herbal medicine in treating DM.

Literature Review: Perbedaan VO2Max antara Pemain Bola Basket dan Pemain Bola Voli Eka Dewi Yanti; Asnawati Asnawati; Dona Marisa
Homeostasis Vol 4, No 3 (2021)
Publisher : Homeostasis

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Abstract: The basic concept of physical fitness indicator is the maximal oxygen consumption (VO2max). This exchange is the best indicator of a person's cardiovascular fitness and endurance. Volleyball and basketball games are one way to improve cardiovascular fitness. The purpose of this literature review is to examine the difference in VO2max between basketball players and volleyball players. The method used is the literature review method in the form of a narrative review, namely by using articles obtained through the literature search process. The articles use in this literatur review are 7 articles. The results of the literature review show that there is a difference between the VO2max of basketball players and the VO2max of volleyball players. VO2max is influenced by several factors, namely genetics, body composition, differences in motion intensity, exercise intensity, exercise duration, physical activity, differences in sample criteria and differences in the tests used. Keywords: VO2max, Cardiorespiratory, Volleyball, Basketball Abstrak: Konsep dasar kesegaran jasmani (physical fitness) indikatornya adalah kapasitas oksigen maksimal (VO2max). Pengukuran ini merupakan indicator...terbaik kebugaran fungsi kardiovaskuler dan daya..tahan..tubuh seseorang. Permainan bola voli dan basket merupakan salah satu cara untuk meningkatkan kebugaran kardiovaskuler. Tujuan literatur review ini untuk meninjau perbedaan VO2max antara pemain basket dan pemain voli. Metode yang digunakan adalah metode literatur review berupa narrative review. Artikel yang digunakan dalam literatur review ini sebanyak 7 artikel. Hasil tinjauan literatur menunjukkan bahwa terdapat terdapat perbedaan antara VO2max pemain bola basket dengan VO2max pemain bola voli. VO2max dipengaruhi oleh beberapa faktor yaitu genetik, komposisi tubuh, perbedaan intensitas gerak, intensitas latihan, durasi latihan, aktivitas fisik, perbedaan kriteria sampel serta perbedaan tes yang digunakan. Kata-kata kunci: VO2 maks, kardiorespirasi, bola basket, bola voli

Hubungan Frekuensi dan Lama Latihan terhadap Kelenturan Otot Penari Modern M Naufal Firdaus; Dona Marisa; Asnawati Asnawati
Homeostasis Vol 2, No 1 (2019)
Publisher : Homeostasis

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Abstract: Muscle flexibility is an important part of physical fitness, which is crucial in helping muscle strength, increasing movement efficiency, coordination, and preventing injury. Flexural muscles will make the fibers in the muscles accustomed to elongation. Therefore, flexible dancers can withstand a great deal of stress compared to dancers who are less flexible. This study aims to determine the relationship of frequency and duration of exercise to the flexibility of modern dancer muscles. This study used an observational analytic method with a crossectional approach. A sample of 30 people who met the inclusion criteria were taken using the purposive sampling technique. The research instrument was a questionnaire and sit and reach box. Data analysis using the Spearman test. The results showed that the frequency of exercise samples was mostly 2 times per week with a length of exercise of mostly 120 minutes. For the flexibility of the muscles the sample is mostly included in the good category. The relationship between exercise duration and muscle flexibility results in a value of ρ value = 0,000. The conclusions from this study indicate a significant relationship between the frequency and duration of training in the flexibility of modern dancers muscles Keywords: frequency of training, duration of training, muscle flexibility, modern dancers Abstrak: Kelenturan otot merupakan bagian penting dari kebugaran fisik, yang membantu kekuatan otot, meningkatkan efisiensi gerakan, koordinasi, dan mencegah cedera. Otot yang lentur akan membuat serat-serat pada otot terbiasa dengan pemanjangan. Karena itu, penari yang lentur dapat bertahan dalam stress yang besar dibandingkan dengan penari yang kurang lentur. Penelitian ini bertujuan untuk mengetahui hubungan frekuensi dan lama latihan terhadap kelenturan otot penari modern. Penelitian ini menggunakan metode observasional analitik dengan pendekatan crossectional. Sampel sebanyak 30 orang yang memenuhi kriteri inklusi diambil dengan teknik purposive sampling. Instrumen penelitian berupa kuesioner dan kotak sit and reach. Analisis data menggunakan uji Spearman. Hasil penelitian didapatkan frekuensi latihan sampel sebagian besar adalah 2 kali per minggu dengan lama latihan sebagian besar 120 menit. Untuk kelenturan otot sampel sebagian besar termasuk dalam kategori good. Hasil analisis menghasilkan nilai ρ value = 0,000. Kesimpulan dari penelitian ini menunjukkan adanya hubungan yang bermakna antara frekuensi dan lama latihan terhadap kelenturan otot penari modern. Kata-kata kunci: frekuensi latihan, lama latihan, kelenturan otot, penari modern

Literature Review: Pengaruh Olahraga terhadap Heart Rate Recovery Penderita Hipertensi Yusril Mubarak; Fauzan Muttaqien; Asnawati Asnawati
Homeostasis Vol 4, No 1 (2021)
Publisher : Homeostasis

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Abstract: Heart rate recovery (HRR) is the difference between the peak heart rate during exercise and the heart rate at 1 minute after stopping exercise and is a predictor of cardiovascular disease such as hypertension. Hypertension is characterized by a decrease in HRR. One way of preventing and non-pharmacological therapy for hypertension and reducing HRR is by exercising. The purpose of this paper is to determine how the effect of exercise on heart rate recovery in patients with hypertension. This writing was done by using the literature review method. Search for articles through the database of medical journals, namely Pubmed, Google Scholar, and Ovid. The articles used for this literature review are 5 articles. Traceable articles in English published in 2001-2020. The conclusion of the five articles reviewed, four articles proved that exercise can increase HRR in patients with hypertension. Exercise that is effective at increasing HRR is aerobic exercise. Keywords: Heart rate recovery, hypertension, exercise Abstrak: Heart rate recovery (HRR) adalah selisih antara detak jantung puncak saat latihan dan detak jantung pada 1 menit setelah penghentian olahraga dan merupakan prediktor penyakit kardiovaskular seperti hipertensi. Hipertensi ditandai dengan terjadinya penurunan HRR. Salah satu cara mencegah dan terapi nonfarmakologi hipertensi maupun penurunan HRR adalah dengan berolahraga. Tujuan dalam penulisan ini adalah untuk mengetahui bagaimana pengaruh olahraga terhadap heart rate recovery penderita hipertensi. Penulisan ini dilakukan dengan metode literature review. Pencarian artikel melalui database jurnal kedokteran yaitu Pubmed, Google Scholar, dan Ovid. Artikel yang digunakan untuk literature review ini sebanyak 5 artikel. Artikel yang ditelusuri berbahasa inggris yang diterbitkan pada tahun 2001-2020. Kesimpulan dari kelima artikel yang ditinjau, empat artikel terbukti bahwa olahraga dapat meningkatkan HRR pada penderita hipertensi. Olahraga yang efektif meningkatkan HRR adalah olahraga aerobik Kata-kata kunci: Heart rate recovery, hipertensi, olahraga

HUBUNGAN INDEKS MASSA TUBUH DAN WAIST HIP RATIO TERHADAP DAYA TAHAN OTOT PADA PENARI MODERN Ivana Ellenora Ellenora; Dona Marisa; Asnawati Asnawati
Homeostasis Vol 2, No 3 (2019)
Publisher : Homeostasis

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Abstract: Muscle endurance is one of the components of health related physical fitness which is defined as the ability of muscles to carry out aerobic metabolism continuously but in a short time muscle fatigue does not occur. Muscle endurance can be influenced by nutritional status and body fat. Nutritional status can be measured by body mass index and body fat can be measured by the waist hip ratio. This study aims to determine the association between body mass index with muscle endurance in modern dancer and association between waist hip ratio with muscle endurance in modern dancer. This research uses the subject of modern dancer research in Banjarmasin. This study was an observational analytic study with a cross sectional method. Thirty one subjects were selected by simple random sampling. The result obtained showed that the average BMI = 21.59 kg/m2, WHR = 0.84, and muscle endurance = 35.35 times/minute. Pearson correlation test results were obtained (p = 0.000, r = -0.982) there was a strong correlation with the negative correlation direction between body mass index and muscle endurance in modern dancers, and (p = 0.000, r = -0.977) there was a strong correlation with the negative correlation direction between waist hip ratio and muscle endurance in modern dancer. Keywords : body mass index, waist hip ratio, muscle endurance, modern dancer Abstrak: Daya tahan otot adalah salah satu dari komponen kebugaran yang berhubungan dengan kesehatan yang didefinisikan sebagai kemampuan otot saat melakukan metabolisme aerobik secara terus menerus tetapi dalam waktu cepat tidak terjadi kelelahan otot. Daya tahan otot dapat dipengaruhi oleh status gizi dan lemak tubuh. Status gizi dapat diukur dengan indeks massa tubuh dan lemak tubuh dapat diukur dengan waist hip ratio. Penelitian ini bertujuan untuk mengetahui hubungan indeks massa tubuh dengan daya tahan otot pada penari modern dan hubungan waist hip ratio dengan daya tahan otot pada penari modern. Penelitian ini menggunakan subyek penelitian penari modern di Banjarmasin. Penelitian ini adalah penelitian observasional analitik dengan pendekatan cross sectional. Sebanyak 31 subyek dipilih secara simple random sampling. Hasil penelitian diperoleh rerata nilai IMT = 21,59 kg/m2, WHR = 0,84, dan daya tahan otot = 35,35 kali/menit. Hasil uji korelasi Pearson didapatkan (p = 0,000, r = -0,982) terdapat korelasi yang kuat dengan arah korelasi negatif antara indeks massa tubuh dengan daya tahan otot pada penari modern, dan (p = 0,000, r = -0,977) terdapat korelasi yang kuat dengan arah korelasi negatif antara waist hip ratio dengan daya tahan otot pada penari modern. Kata-kata kunci:indeks massa tubuh, waist hip ratio, daya tahan otot, penari modern

Perbedaan Waktu Reaksi Anggota Sbrunners yang Joging Teratur dan Tidak Teratur Muhammad Nardho Pratama; Asnawati Asnawati; Ahmad Husairi
Homeostasis Vol 3, No 1 (2020)
Publisher : Homeostasis

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Abstract: Regular exercise has benefits for the body such as improving health, increasing attention and concentration, improving nerve function, and improving blood flow. These benefits can make a person's reaction time faster. The South Borneo Runners community has a regular jogging schedule but not all members follow the schedule. This study aims to determine whether there are differences in reaction times between South Borneo Runners members who jog regularly and irregularly. This research is an observational analytic study with cross-sectional approach. Samples were determined using a consecutive sampling technique and 41 subjects were obtained. Subjects were divided into 2 groups, the regular jogging group of 26 people and the irregular jogging group of 15 people. Measurement of reaction time using Kosinski's time reaction software. Data were analyzed using an unpaired t test and showed p = 0.202. It can be concluded that there is no difference in reaction times between South Borneo Runners members who jog regularly and irregularly. Keywords: reaction time, regular jogging, exercise. Abstrak: Olahraga teratur memiliki manfaat bagi tubuh seperti meningkatkan kesehatan, meningkatkan perhatian dan konsentrasi, memperbagus fungsi saraf, dan memperlancar aliran darah. Berbagai manfaat tersebut dapat membuat waktu reaksi seseorang semakin cepat. Komunitas South Borneo Runners memiliki jadwal olahraga joging yang teratur tetapi tidak semua anggotanya mengikuti jadwal tersebut. Penelitian ini bertujuan untuk mengetahui apakah terdapat perbedaan waktu reaksi antara anggota South Borneo Runners yang joging teratur dan tidak teratur. Penelitian ini adalah penelitian observasional analitik dengan rancangan cross sectional. Sampel ditetapkan menggunakan teknik consecutive sampling dan didapatkan sebanyak 41 subjek penelitian. Subjek terbagi menjadi 2 kelompok, yaitu kelompok joging teratur sebanyak 26 orang dan kelompok joging tidak teratur sebanyak 15 orang. Pengukuran waktu reaksi menggunakan Kosinski’s time reaction software. Data dianalisis menggunakan uji t tidak berpasangan dan didapatkan nilai p=0,202. Jadi, dapat disimpulkan bahwa tidak ada perbedaan waktu reaksi antara anggota South Borneo Runners yang joging teratur dan tidak teratur. Kata-kata kunci: waktu reaksi, joging teratur, olahraga.

Literature Review: Perbedaan Waktu Reaksi antara Pemain Voli dan Pemain Basket Rafida Ikhsania Camalis; Asnawati Asnawati; Dona Marisa
Homeostasis Vol 4, No 3 (2021)
Publisher : Homeostasis

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Abstract: Basketball and volleyball are sports that require quick reactions in their game, these two sports have some similarities in technical motion. Writing this literature review aim to summarize the comparison of reaction times between volleyball players and basketball players. The method used is the narrative review method, namely by using articles obtained through a literature search process. The writing was conducted by analyzing related literature obtained from the search results on medical journal databases, such as PubMed and Google Scholar. Included articles are in English and published in 2009-2020. The review included 5 articles. Based on the five articles, there is a significant difference in reaction time between the reaction time of volleyball players and basketball players’ reaction time, with the reaction time values obtained faster for basketball players than for volleyball players. Significant or not the difference in reaction time is influenced by several factors, such as arousal, age, exercise intensity, fatigue, fasting, exercise, awareness, differences in sample criteria and the test used. Keywords: reaction time, response time, basketball, volleyball Abstrak: Olahraga basket dan voli merupakan olahraga yang memiliki beberapa kesamaan dalam gerak teknik dan membutuhkan reaksi yang cepat dalam permainannya. Penulisan literature review ini bertujuan untuk mengetahui manfaat perbedaan waktu reaksi antara pemain voli dan pemain basket. Metode yang digunakan adalah metode narrative review, yaitu dengan menggunakan artikel yang didapat melalui proses pencarian literatur. Penulisan dilakukan dengan menganalisis literatur terkait yang didapatkan dari hasil pencarian di PubMed dan Google Scholar. Artikel yang disertakan menggunakan bahasa Inggris dan dipublikasikan tahun 2009-2020. Sebanyak 5 artikel disertakan dalam literature review ini. Berdasarkan kelima artikel tersebut terdapat perbedaan waktu reaksi yang signifikan antara pemain voli dan pemain basket, dengan nilai waktu reaksi lebih cepat pada pemain basket. Signifikan atau tidak perbedaan waktu reaksi dipengaruhi oleh beberapa faktor yaitu semangat pemain, usia, intensitas latihan, kelelahan, puasa, olahraga, kesadaran, perbedaan kriteria sampel dan test yang digunakan. Kata-kata kunci: waktu reaksi, waktu respon, basket, voli

Hubungan Persen Lemak Tubuh dengan Kapasitas Oksigen Maksimal pada Calon Jemaah Haji Rahma Jayanti; Huldani Huldani; Asnawati Asnawati
Homeostasis Vol 2, No 1 (2019)
Publisher : Homeostasis

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maximal oxygen capacity (VO2 max). There are many factors that affect VO2 max, one of them is body fat percent. The purpose of this study is to find out the relationship between body fat percent with maximal oxygen capacity (VO2 max) in prospective Hajj pilgrims. The study sample consisted of 50 prospective Hajj pilgrims Hulu Sungai Tengah regency in 2018. This study is an analytic descriptive with cross sectional approach. Body fat percent measured by carada scan and VO2 max by rockport test. The result show research subjects which obesity with less VO2 max is 93,9% while research subjects which has body fat percent normal with good VO2 max is 35,3%. The data analyzed by Fisher exact test with a confidence level of 95% the result revealed p = 0,013, so it can be concluded there are meaningful relationship between body fat percent and maximal oxygen capacity (VO2 max). Keywords: body fat percent, maximal oxygen capacity, hajj pilgrims. Abstrak: Ketahanan kardiorespirasi saat beraktivitas fisik dapat diketahui melalui pengukuran kapasitas oksigen maksimal (VO2 maks). Banyak faktor yang dapat mempengaruhi VO2 maks salah satunya adalah persen lemak tubuh. Tujuan dari penelitian ini adalah untuk mengetahui hubungan persen lemak tubuh dengan kapasitas oksigen maksimal pada calon jemaah haji. Sampel penelitian terdiri dari 50 orang calon jemaah haji Kabupaten Hulu Sungai Tengah tahun 2018 yang telah memenuhi kriteria inklusi. Rancangan penelitian yang digunakan adalah deskriptif analitik dengan pendekatan cross sectional. Persen lemak tubuh diukur dengan carada scan dan VO2 maks diukur dengan rockport test. Hasil penelitian menunjukkan subyek penelitian obesitas dengan VO2 maks kurang adalah 93,9% sedangkan subyek penelitian normal dengan VO2 maks baik 35,3%. Analisis statistik data menggunakan uji Fisher exact dengan tingkat kepercayaan 95% didapatkan nilai p=0,013, sehingga dapat disimpulkan terdapat hubungan yang bermakna antara persen lemak tubuh dengan kapasitas oksigen maksimal (VO2 maks). Kata-kata kunci: persen lemak tubuh, kapasitas oksigen maksimal, jemaah haji.

HUBUNGAN IMT DAN LINGKAR PERUT DENGAN KAPASITAS OKSIGEN MAKSIMAL CALON JEMAAH HAJI Fedia Riska Amilia; Huldani Huldani; Asnawati Asnawati
Homeostasis Vol 2, No 2 (2019)
Publisher : Homeostasis

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Abstract: Maximum oxygen capacity (VO2 max) is a parameter of a person's fitness level. VO2 max is influenced by several factors, one of which is nutritional status. Nutritional status can be assessed based on BMI and abdominal circumference. This study aims to determine the relationship of BMI and abdominal circumference in prospective pilgrims of Hulu Sungai Tengah Regency in 2018. This research method used observational analytic with cross sectional approach. The number of samples is 55 people who meet the inclusion criteria. Measuring VO2 max using the rockport test. The results showed that obese BMI subjects had adequate VO2 max as much as 68.96% and central obesity had less VO2 max as much as 90%. Data on IMT relationships with VO2 max were analyzed using the chi square test with p=0.008 and abdominal circumference relationship with VO2 max using the fisher exact test with a confidence level of 95%, p=0.018 so that it can be concluded that there is a significant relationship between BMI and abdominal circumference with VO2 max. Keywords: maximal oxygen capacity, body mass index, abdominal circumference, pilgrims Abstrak: Kapasitas oksigen maksimal (VO2 maks) merupakan parameter tingkat kebugaran seseorang. VO2 maks dipengaruhi oleh beberapa faktor, salah satunya adalah status gizi. Status gizi dapat dinilai berdasarkan IMT dan lingkar perut. Penelitian ini bertujuan untuk mengetahui hubungan IMT dan lingkar perut dengan VO2 maks pada calon jemaah haji Kabupaten Hulu Sungai Tengah tahun 2018. Metode penelitian yang digunakan adalah observasional analitik dengan pendekatan cross sectional. Jumlah sampel sebanyak 55 orang yang memenuhi kriteria inklusi. Pengukuran VO2 maks menggunakan rockport test. Analisis data menggunakan uji chi square dan uji fisher exact dengan tingkat kepercayaan 95%. Hasil penelitian didapatkan subjek penelitian dengan IMT obesitas memiliki VO2 maks cukup sebanyak 68,96% dan obesitas sentral memiliki VO2 maks kurang sebanyak 90%. Hubungan IMT dengan VO2 maks dianalisis menggunakan uji chi square didapatkan nilai p=0,008 dan hubungan lingkar perut dengan VO2 maks menggunakan uji fisher exact didapatkan nilai p=0,018 sehingga dapat disimpulkan terdapat hubungan yang bermakna antara IMT dan lingkar perut dengan VO2 maks. Kata-kata kunci: kapasitas oksigen maksimal, indeks massa tubuh, lingkar perut, jemaah haji.

Literature Review: Perbedaan Konsumsi Oksigen Maksimal antara Metode Tes Lapangan dan Metode CPET Millenia Bella Putri Syafrina; Asnawati Asnawati; Fauzan Muttaqien; Huldani Huldani; Mohammad Bakhriansyah
Homeostasis Vol 5, No 1 (2022)
Publisher : Homeostasis

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Abstract: Maximum oxygen consumption (VO2 max) is the maximum amount of oxygen that can be consumed during continuous physical activity until fatigue occurs. VO2 max can be measured using the field test method or the CPET method. The purpose of this literature review is to analyze the difference in the maximum oxygen consumption value between the field test method and the CPET method. The reference data in this article review was obtained by searching using PubMed and Google Scholar published in 2011 to 2021. After the search and selection process of articles, 6 articles were included in this literature review. A total of 6 articles, 5 articles show that there was not significant difference between the VO2 max value using the field test method while in another article show that there was a significant difference. Keywords: VO2 max, field test, CPET. Abstrak: Konsumsi oksigen maksimal (VO2 maks) adalah jumlah maksimal oksigen yang dapat dikonsumsi selama terjadi aktivitas fisik secara terus menerus sampai akhirnya terjadi kelelahan. VO2 maks dapat diukur menggunakan metode tes lapangan maupun metode CPET. Tujuan penulisan literature review ini adalah untuk menganalisis perbedaan nilai konsumsi oksigen maksimal antara metode tes lapangan dan metode CPET. Data acuan dalam kajian artikel ini didapatkan dengan penelusuran menggunakan PubMed dan Google Scholar yang dipublikasikan pada tahun 2011 hingga tahun 2021. Setelah proses pencarian dan seleksi artikel, didapatkan 6 artikel yang disertakan pada literature review ini. Dari 6 artikel tersebut sebanyak 5 artikel yang menyebutkan bahwa terdapat perbedaan yang tidak signifikan antara nilai VO2 maks menggunakan metode tes lapangan dan menggunakan CPET sedangkan pada 1 artikel lain menyebutkan bahwa terdapat perbedaan yang signifikan. Kata-kata kunci : VO2 maks, tes lapangan, CPET

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