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All Journal Jurnal Ilmiah Kesehatan (JIKA) KOPEMAS
Ricadonna Raissa
Universitas Brawijaya
Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences

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Pemberian Dietilnitrosamin dan Karbontetraklorida Pada Gambaran Histologi Ginjal Tikus (Rattus Norvegicus) Almas Dwi Khairana; Ricadonna Raissa; Wibi Riawan; Suharti Suharti; Hendra Susanto; Aulanni’am Aulanni’am
Jurnal Ilmiah Kesehatan (JIKA) Vol. 4 No. 1 (2022): Volume 4 Nomor 1 April 2022
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v4i1.242

Abstract

Diethylnitrosamine (DEN) is a metabolic product of various foods and beverages in which there are preservatives in the form of nitrate and nitrite. Nitrosamines are found in various products such as alcoholic beverages, processed meats, cigarettes, and cosmetic products. DEN is toxic and carcinogenic to organs such as the liver, lungs, kidneys, skin, stomach, and blood. In addition to giving DEN compounds, there are also CCl4 compounds as tumor promoter agents known as genotoxic substances that can increase the risk of genetic errors and stimulate cells to become malignant neoplasms. Administration of DEN and CCl4 induction can damage various organs of the body, one of which is the kidney. In a healthy body, angiogenesis plays a role in wound healing and the formation of new tissue. However, angiogenesis also contributes to carcinogenesis or the uncontrolled growth of cancer cells, and is malignant when the body is contaminated with toxic substances. Therefore, to determine the effect of the administration of DEN and CCl4 observations were made using the immunohistochemical method, to see differences in the histology of the kidneys of experimental animals, the positive control group, and the negative control group based on the VEGF angiogenesis factor. From these results, there are significant differences. In the negative group, there was no necrosis and high-value VEGF expression, but in the positive group, there was necrosis and a decrease in the value of VEGF expression compared to the negative control group.
“SEKOLAH ANTI RABIES”: EDUKASI PENGENALAN, PENCEGAHAN, DAN PENANGANAN RABIES PADA SISWA SMA DI KOTA MALANG Ricadonna Raissa; Zelbina Silvia Mirzenti; Tyas Fachrunnisa; Regina Vanesa Tesalonika Prasita Atmaja; Sabrina Choirunnisa; Gretania Residiwati; Reza Yesica; Tiara Widyaputri; Ahmad Amir Akmal Bin Abdul Hamid; Amir Aiman Bin Muhaidin; Fikrie Bin Fakharoll Rodziee
Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024 Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5
Publisher : Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024

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Abstract

Rabies merupakan penyakit zoonosis yang menjadi masalah kesehatan utama di Indonesia. Penyakit ini disebabkan oleh virus rabies yang menyerang susunan saraf pusat dan dapat berakibat fatal jika tidak segera ditangani. Kegiatan Pengabdian Masyarakat Tematik “Sekolah Anti Rabies” ini dilaksanakan untuk meningkatkan pengetahuan siswa SMA di Kota Malang tentang penyakit rabies dan penanggulangannya. Kegiatan ini meliputi sosialisasi, sesi tanya jawab, serta pre-test dan post-test untuk mengukur pemahaman siswa. Hasil kegiatan menunjukkan peningkatan yang signifikan, dengan rata-rata skor pre-test sebesar 73,33% meningkat menjadi 87,45% pada post-test, dengan peningkatan sebesar 14,12%. Tingkat kepuasan peserta juga tinggi, menunjukkan efektivitas metode edukasi
Co-Authors Ahmad Amir Akmal Bin Abdul Hamid Almas Dwi Khairana Amir Aiman Bin Muhaidin Aulanni'am, Aulanni'am Fikrie Bin Fakharoll Rodziee Gretania Residiwati Hendra Susanto Regina Vanesa Tesalonika Prasita Atmaja Reza Yesica Sabrina Choirunnisa Suharti Tiara Widyaputri Tyas Fachrunnisa Wibi Riawan Zelbina Silvia Mirzenti