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Journal : Jurnal MedScientiae

Tinjauan Pustaka Terbaru Peran Omega 3 Pada Dry Eye Anugrahsari, Santi; Lesmana, Andri; Korwa, Daniela Dirgantari; Kumala Sari, Ni Putu Winda
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3707

Abstract

Dry eye disease (DED) or dry eye disease is a common condition in every country. Dry eyes can cause symptoms such as discomfort or a cycling sensation, red eyes and a feeling of blockage. Inflammation is one of the underlying pathophysiology of dry eyes. One of the therapeutic approaches that has received major attention is the use of omega-3 fatty acid supplements, which are known to have anti-inflammatory properties and can support eye health. Recent studies have shown that omega-3, especially EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), can improve tear quality, improve meibomian gland function, and increase tear production in people with dry eyes. In addition, omega-3 also plays a role in reducing symptoms of dry eyes, although several studies have shown significant results, but the effectiveness of omega-3 in managing dry eyes still requires further research, especially in determining the optimal dose and duration of therapy. This literature review aims to review the latest developments related to the role of omega-3 in dry eye therapy and explore the underlying effects of omega-3 on dry eyes. Further research is expected to provide stronger evidence regarding the role of omega-3 in dry eye therapy.
Gambaran Klinis dan Histopatologi Karsinoma Urotelial di Salah Satu RS Swasta Jakarta Barat Tahun 2021-2023 Andri Lesmana; Christina, Shintia; Indarto, Fanny; Boedijono, Freciyana
Jurnal MedScientiae Vol. 4 No. 3 (2025): Desember
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i3.3597

Abstract

Urothelial carcinoma is a type of cancer that can occur in organs lined with urothelial cells, specifically in the urinary tract. Globally, in 2022, bladder cancer accounted for 3% of all cancer cases. Objective to determine the clinical and histopathological characteristics of urothelial carcinoma patients at a private hospital in West Jakarta from 2021 to 2023. This study is a descriptive study with a retrospective approach conducted at a private hospital in West Jakarta. The sample size was determined using the consecutive sampling technique, resulting in a total of 40 samples. The highest number of urothelial carcinoma cases was recorded in 2021, with 21 cases (52.5%). In this study, 14 cases (35.0%) were found in the 60-69 age group. The most common clinical complaint was gross hematuria, observed in 34 samples (85.0%). Histopathological examination showed that the most frequent pathological stage was pT1, found in 14 samples (35.0%), while the most common pathological grading was high grade, observed in 29 samples (72.5%). The incidence of urothelial carcinoma at a private hospital in West Jakarta from 2021 to 2023 was 40 cases, with gross hematuria being the most common clinical complaint. The highest incidence was in the 60-69 age group. The most frequent pathological stage was pT1, and the most common pathological grading was high grade.