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HUBUNGAN INVASI MIOMETRIUM PADA KARSINOMA EDNOMETRIUM DENGAN INVASI LIMFOVASKULAR DAN GRADE HISTOLOGIK Christina, shintia; Kartika Setyaningsih, Chandra; Pelita Sukma Hermawan, Puspa
Jurnal Kedokteran YARSI Vol 27, No 3 (2019): SEPTEMBER - DESEMBER 2019
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jky.v27i3.1204

Abstract

Latar Belakang : Karsinoma endometrium menduduki urutan keenam kanker pada wanita. Faktor prediktor prognosis pada karsinoma endomerium adalah grade histologik, invasi miometrium dan invasi limfovaskular. Kejadian metastasis kelenjar getah bening melalui limfovaskular pada karsinoma endometrium meningkat dengan adanya invasi tumor ke miometrium yang lebih dalam. Tujuan : Pada penelitian ini ingin diketahui apakah invasi miometrium mempunyai hubungan dengan invasi limfovaskular dan grade histologik. Apakah semakin tinggi grade histologik maka kejadian invasi miometrium dan invasi limfovaskular semakin meningkat ? Metodologi : Penelitian analitik kategorik tidak berpasangan dan retrospektif dengan menilai ulang slide histopatologik pada karsinoma endometrium di RSUD Tarakan. Penilaian ulang meliputi grade histologik, invasi miometrium dan invasi limfovaskular. Hasil : Didapatkan hubungan yang bermakna antara invasi miometrium dengan kejadian invasi limfovaskular (p=0,029). Hubungan derajat histologik dengan kejadian invasi miometrium dan invasi limfovaskular didapatkan tidak bermakna pada penelitian ini.  Kesimpulan : Semakin tinggi grade histologik tidak meningkatkan kemungkin invasi ke miometrium maupun invasi limfovaskular, sedangkan invasi ke miometrium yang lebih dari setengah ketebalan miometrium meningkatkan kemungkinan adanya invasi limfovaskular yang berarti meningkatkan risiko metastasis.  
HUBUNGAN ANTARA LESI PRAKANKER SERVIKS DENGAN SOSIODEMOGRAFI PEREMPUAN DI KECAMATAN LEGOK KABUPATEN TANGERANG TAHUN 2018 Claritha, Destiyana Cika; Dewi, Chandra; Christina, Shintia
Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan Vol 4, No 1 (2020): Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan
Publisher : Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/jmstkik.v4i1.6321

Abstract

Cervical and breast cancer are the highest prevalence cancer in Indonesia in 2013 which caused death to Indonesian women, cervical cancer by 0.8‰ and breast cancer by 0.5‰. Precancerous lesions of the cervix also known as cervical intraepithelial lesions (Cervical Intraepithelial Neoplastic) are the beginning of changes to cervical carcinoma. In general, precancerous lesions of the cervix originate from the squamous columnar junction in the uterine cervix, which undergoes the process of metaplasia. This study aims to determine whether there is a relationship between precancerous cervical lesions and sociodemography of women in Kecamatan Legok Kabupaten Tangerang in 2018. This study uses an analytical study with cross sectionaI approach. The population is all women in Kecamatan Legok Kabupaten Tangerang who had sexual relations. Total sample are 47 people. Keywords: cervical cancer, cervical precancerous lesions, parity ABSTRAKPenyakit kanker serviks dan payudara merupakan penyakit kanker dengan prevalensi tertinggi di Indonesia pada tahun 2013 yang menyebabkan kematian pada perempuan Indonesia, yaitu kanker serviks sebesar 0,8‰ dan kanker payudara sebesar 0,5‰. Lesi prakanker pada serviks dikenal juga dengan sebutan lesi intraepitelial serviks (Cervical Intraephitelial Neoplasia) merupakan awal dari perubahan menuju karsinoma serviks. Pada umumnya lesi prakanker serviks ini berawal dari daerah squamocolumnar junction pada serviks uteri yang mengalami proses metaplasia. Penelitian ini bertujuan untuk mengetahui adakah hubungan antara lesi prakanker serviks dengn sosiodemografi perempuan di Kecamatan Legok Kabupaten Tangerang tahun 2018. Penelitian ini merupakan studi analitik dengan pendekatan cross sectionaI. Populasi penelitian adalah semua perempuan di Kecamatan Legok Kabupaten Tangerang yang sudah berhubungan seksual. Total sampel 47 orang.
Prevalensi Kista Ovarium Di RS Swasta di Jakarta Barat pada tahun 2017-2021 Lauw, Jessica Amelia; Christina, Shintia; Pasaribu, Donna Mesina
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3189

Abstract

Ovarian cysts are generally divided into functional cysts, endometriosis, and neoplasm cysts with benign, borderline and malignant properties. Ovarian cysts occur in 82% of women of productive age. In general, ovarian cysts found are benign and the rest are a journey to malignancy. Detailed prevalence rates regarding ovarian cysts for each type of ovarian cyst have not been found in Indonesia, especially at Hermina Daan Mogot Hospital This type of research is descriptive, using a cross sectional design. This research was carried out at Hermina Daan Mogot Hospital from 2017 – 2021.From the results obtained, the most histopathological diagnosis was endometriosis with a total of 117 subjects (45.5%). The largest age group is 36.7 – 45.6 years old with 96 subjects and the least age category is ≥ 65.7 years old with 8 subjects. The most common type of ovarian cyst is endometriosis. The highest age range is 36.7 – 45.6 years.
Gambaran Klinis dan Histopatologi Karsinoma Prostat di Salah Satu RS Swasta Jakarta Barat Tahun 2021-2023 Firman Kevin Gratio Nainggolan; Christina, Shintia; Boedijono, Freciyana; Angeline, Reni
Jurnal MedScientiae Vol. 4 No. 1 (2025): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i1.3588

Abstract

Prostate carcinoma is a type of cancer that occurs in the prostate gland in men. Globally, in 2022, 14,2% of prostate cancer cases were recorded in the male population. In the Indonesian male population, there were 7,0% of prostate cancer cases. This study aims to determine the clinical and histopathological features of prostate carcinoma patients at one of Jakarta Barat private hospital in 2021–2023..This study is a descriptive study with a retrospective approach at one of private hospital in West Jakarta. Determination of sample size using consecutive sampling technique with a sample size of 79 samples. The most cases of carcinoma were recorded in 2021 with 35 samples (44,3%). In this study, there were 36 cases in the age range >70–80 years (45,6%). The most common clinical complaint was LUTS with 54 samples (68,4%). The most common sampling technique was TRUS-biopsy with 35 samples (44,3%). The results of histopathological examination were dominated by acinar adenocarcinoma with 72 samples (91,1%). A total of 27 samples were Gleason Class Group 5 (34,2%). The incidence of prostate carcinoma at one of Jakarta Barat private hospital in 2021-2023 was 79 samples with the most common complaint being LUTS. The most common incidents occurred in the age range of >70-80 years. The most frequently used method of sampling was TRUS-biopsy with acinar adenocarcinoma being the most common histopathological result found and Gleason Grade Group 5 dominating in this study.
Patterns of Kidney Diseases in Native Biopsies: A Single-Center Experience Pratiwi, Regina Anjani Budi; Christina, Shintia; Nilasari, Dina
Indonesian Journal of Kidney and Hypertension Vol 2 No 1 (2025): Volume 2 No. 1, April 2025
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v2i1.181

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Background: Kidney biopsy is the definitive diagnostic method for kidney disease, providing essential histopathological information for prognosis and treatment. However, in Indonesia, comprehensive data on kidney biopsy patterns remain limited, making it difficult to assess disease prevalence and epidemiological trends. Objective: To analyze the epidemiology of biopsy-confirmed kidney diseases in a single-center cohort and evaluate the distribution of clinical and histopathological diagnoses. Methods: A retrospective descriptive analysis was performed on patients who underwent a kidney biopsy at Siloam Hospital Kebon Jeruk between January 2021 and August 2024. Data on demographics, clinical manifestations, biopsy indications, histopathological findings, and immunofluorescence results were analyzed using descriptive statistics. Results: A total of 45 kidney biopsies were conducted, resulting in a biopsy rate of 5.24 per 1,000 individuals, higher among young adults (15–44 years). The median patient age was 43 years, with a nearly equal male-to-female ratio. Nephrotic syndrome was the leading clinical presentation (35.9%), followed by nephritic syndrome (33.3%). Hematuria and proteinuria (35.6%) were the most frequent biopsy indications. Glomerular diseases represented as majority of histopathological diagnoses, with focal segmental glomerulosclerosis (FSGS) being the most common finding (37.8%), followed by lupus nephritis and IgA nephropathy. A rare case of monoclonal gammopathy of renal significance was also identified. Conclusion: This study provided insight into biopsy-confirmed kidney disease patterns in Indonesia. The predominance of glomerular diseases, particularly FSGS, aligns with global trends. The low biopsy rate underscores the need for expanded nephrology services and further multicenter studies to develop a comprehensive national kidney disease registry.
Peran Kode Etik dan Integritas Guru PAK dalam Membentuk Karakter Peserta Didik Christina, Shintia; Tambunan, Ruhut Parningotan; Arifianto, Yonatan Alex
Jurnal Lentera Nusantara Vol 4, No 2 (2025): Lentera Nusantara: Jurnal Teologi dan Pendidikan Kristen
Publisher : Sekolah Tinggi Teologi Kanaan Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59177/jln.v4i2.390

Abstract

Kode etik dan integritas guru pendidikan agama Kristen memegang peran fundamental dalam membentuk karakter peserta didik. Guru bukan hanya sebagai penyampai materi, tetapi juga sebagai teladan dalam menerapkan nilai-nilai moral dan spiritual yang diajarkan. Penelitian ini mengeksplorasi bagaimana kepatuhan terhadap kode etik dan integritas guru pendidikan agama Kristen berkontribusi terhadap pembentukan karakter peserta didik melalui proses pembelajaran yang berlandaskan nilai-nilai kristiani. Dengan metode kualitatif, penelitian ini mengidentifikasi berbagai aspek etika profesi guru pendidikan agama Kristen serta implikasinya terhadap perkembangan karakter siswa. Hasil penelitian menunjukkan bahwa guru dengan integritas tinggi mampu menciptakan lingkungan pembelajaran yang mendukung internalisasi nilai-nilai moral, seperti kasih, kejujuran, tanggung jawab, dan disiplin. Dengan demikian, pembentukan karakter peserta didik tidak hanya terjadi melalui pengajaran teoritis, tetapi juga melalui keteladanan dan interaksi sosial. Penelitian ini bertujuan untuk menganalisis peran kode etik dan integritas guru PAK dalam membentuk karakter peserta didik serta mengidentifikasi strategi efektif dalam penerapannya. Kebaharuan pada penelitian ini terletak pada pendekatan holistik yang menghubungkan kode etik, integritas guru, dan pembentukan karakter peserta didik secara langsung, menawarkan perspektif baru dalam pendidikan agama Kristen.
Hubungan Pola Makan dengan Penyakit Kanker Kolorektal Firman Riscky Mansyur; Angeline, Reni; Christina, Shintia; Kertadjaya, Wiwi
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3741

Abstract

Cancer is the second leading cause of death globally. Colorectal cancer is one of the most common cancers worldwide. Referring to GLOBOCAN data, in general colorectal cancer is the third highest incidence of cancer after lung cancer and breast cancer. This is attributed to the diet that affects colorectal cancer. Most colorectal cancer are still closely related to genetics. In addition to genetic factors, food intake factors also closely related to colorectal cancer. Current research shows colorectal cancer occurs due to genetic mutations and inflammatory bowel disease. This literature review uses a Literature review design using a search method with a library of research articles or journals through PubMed and other journal sources. The results of the literature review are associated with dietary pattern that affect colorectal cancer, red mead intake is related to the growth of colorectal cancer, while high fiber food can help reduce the risk of colorectal cancer.