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All Journal Majalah Obstetri dan Ginekologi Excellent Midwifery Journal
Letta Sari Lintang
Universitas Sumatera Utara
Health Professions Medicine & Pharmacology Public Health

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Hubungan Kadar Follicle Stimulating Hormone dengan Keluhan Urogenital Pada Wanita Menopause Sarma Nursani Lumbanraja; Muhammad Fidel Ganis Siregar; Ichwanul Adenin; Letta Sari Lintang; Binarwan Halim; Irwin Lamtota Lumbanraja
Excellent Midwifery Journal Vol 3, No 2 (2020): EDISI OKTOBER
Publisher : STIKes Mitra Husada Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (237.429 KB) | DOI: 10.55541/emj.v3i2.129

Abstract

Tujuan: Untuk mengetahui hubungan kadar Follicle Stimulating Hormone (FSH) dengan keluhan urogenital pada wanita menopauseMetode: Penelitian ini merupakan studi potong lintang. Sampel adalah wanita menopause yang telah berhenti haid minimal 3 tahun. Penelitian dilakukan di Klinik Sari Mutiara Diski. Pada pasien akan dilakukan pemeriksaan kadar FSH dan penilaian keluhan urogenital dengan menggunakan kuisoner Most Bothersome Symtoms (MBS). Data akan dianalisa dengan menggunakan SPSS dan secara statistik dengan menggunakan uji T independent dan Chi-square. Nilai P < 0.05 dianggap signifikan.Hasil: Dari 30 sampel penelitian didapatkan karateristik wanita menopause dengan rerata usia 56.4±2.5 tahun, lama menopause 4.2±2.1 tahun, IMT 26.5±3.3 kg/m2, Paritas 3.1±1.2, dan kadar FSH 69.7±11.4 mIU/mL. Didapatkan perbedaan bermakna rerata kadar FSH pada kelompok dengan keluhan urogenital dan tanpa keluhan keluhan urogenital (P = 0.03). Didapatkan perbedaan bermakna kelompok FSH  60 mIU/mL dengan kelompok FSH > 60 mIU/mL terhadap adanya keluhan urogenital (P < 0.001)Kesimpulan: Kadar FSH > 60 mIU/mL berhubungan dengan adanya keluhan urogenital pada wanita menopause Kata Kunci: Menopause, Follicle Stimulating Hormone, FSH, Keluhan Urogenital
Comparison of Neutrophil Lymphocyte Ratio and Platelet Lymphocyte Ratio levels in ovarian cyst among epithelial ovarian cancer patients at RSUP H. Adam Malik Medan, Indonesia Sari Dewi, Mega; Yustin Simanjuntak, Roy; Sari Lintang, Letta; Fahdhy, Muhammad; Edianto, Deri; Sitepu, Makmur
Majalah Obstetri & Ginekologi Vol. 31 No. 3 (2023): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V31I32023.117-122

Abstract

HIGHLIGHTS Neutrophil Lymphocyte Ratio (NLR) and Platelet Lymphocyte Ratio (PLR) have potential as independent prognostic markers for ovarian cancer. This research was to evaluate NLR and PLR levels in ovarian cysts with epithelial ovarian cancer patients at RSUP H. Adam Malik Medan, Indonesia.   ABSTRACT Objective: To assess Neutrophil Lymphocyte Ratio (NLR) and Platelet Lymphocyte Ratio (PLR) as independent prognostic markers in epithelial ovarian cancer patients at RSUP H. Adam Malik Medan, Indonesia, considering the disease's common occurrence and typically late-stage diagnosis with a poor prognosis due to inflammatory processes implicated in malignancy mechanisms. Materials and Methods: A comparative case-control study was conducted at the Department of Obstetrics and Gynecology, RSUP H. Adam Malik Medan, from December 2019 to February 2020. The study included 40 patients each diagnosed with ovarian cysts and epithelial ovarian cancer. Bivariate analysis was conducted using independent T-test for normally distributed data and the Mann-Whitney test for non-normally distributed data. Significance was established at p <0.05. Results: The median NLR in the ovarian cancer group was 2.45 (1.06 to 38.44) and in the ovarian cysts group was 2.34 (1.44 to 3.78). Median PLR levels in ovarian cancer were 12813.94 (3178.08 to 19040.0) and in ovarian cysts were 11138.15 (5026.18 to 22839.51). Statistical analysis revealed no significant difference in NLR and PLR levels between ovarian cancer and ovarian cysts (p >0.05). Conclusion: NLR and PLR levels demonstrated no significant difference between ovarian cancer and ovarian cyst patients at RSUP H. Adam Malik Medan, Indonesia. However, NLR and PLR can still serve as valuable markers for identifying malignant processes in patients suspected of malignancy.
Co-Authors Binarwan Halim Deri Edianto Fahdhy, Muhammad Ichwanul Adenin Irwin Lamtota Lumbanraja M. Fidel Ganis Siregar Makmur Sitepu, Makmur Sari Dewi, Mega Sarma Nursani Lumbanraja Yustin Simanjuntak, Roy