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All Journal CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Jurnal Kimia (Journal of Chemistry) International Journal of Biosciences and Biotechnology Buletin Udayana Mengabdi Ecotrophic, Journal of Environmental Science Journal of Science and Applicative Technology Chimica et Natura Acta ISM (Intisari Sains Medis) : Jurnal Kedokteran Jurnal Media Sains Journal of Multidisciplinary Applied Natural Science Jurnal Ilmu Pendidikan Indonesia
N. W. Bogoriani
Program Studi Kimia FMIPA Universitas Udayana, Jimbaran, Bali, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Environmental Science Immunology & microbiology Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Physics

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Journal : Journal of Science and Applicative Technology

 1 
UJI AKTIVITAS EKSTRAK BUNGA KECOMBRANG (Etlingera elatior Jack) SEBAGAI HIPOLIPIDEMIA PADA TIKUS WISTAR OBESITAS Sri Wardani; Ni Wayan Bogoriani; Ni Luh Rustini
Journal of Science and Applicative Technology Vol 6 No 2 (2022): Journal of Science and Applicative Technology December Chapter
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM), Institut Teknologi Sumatera, Lampung Selatan, Lampung, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35472/jsat.v6i2.1000

Abstract

Kecombrang (Etlingera elatior Jack) is a plant that has potential for hypolipidemia. Kecombrang has secondary metabolites consisting of tannins, saponins, alkaloids, steroids, terpenoids, phenolics, and flavonoids. The purpose of this study was to determine the hypolipidemic activity of kecombrang flower methanol extract in obesed Wistar rats fed a high-fat diet. The test animals used in this study were 18 female white rats aged two months, weight of ± 150 grams. The test animals were divided into three groups, namely normal control (only given standard feed), high-fat control (obesed rats with high-fat diet), and flower treatment group (obesed rats with a high-fat diet + flower methanol extract 100 mg/kgBW) orally for 30 days. The results showed that kecombrang flowers reduced total cholesterol levels by 55.5%, triglycerides (TG) by 57.4%, LDL by 76.73%, and increased HDL by 42.96%. The kecombrang flower has the potential for hypolipidemia which is characterized by a decrease in total cholesterol, TG, LDL, and can increase HDL levels in obese rats significantly (p<0.05).
Co-Authors A. A. Bawa Putra A. Intan Saridewi Abd. Rasyid Syamsuri Adnyana , I Made Dwi Mertha Anak Agung Istri Agung Mayun Laksmiwati Dwi Cahya Putra I M E. P. Siregar I M, Sukadana I Nengah Wirajana I Wayan Suirta I. A. R. Astiti Asih Jeane, Magda Mahayani, Putu Ayu Erna Miftakul Sururi N. M. T. Juliasari Ni Komang Ariati Ni Luh Gede Sudaryati Ni Luh Rustini Ni Luh Utari Sumadewi Ni Made Puspawati Ni Made Suaniti Ni Pt. Pande Mirah Surya Dewi Ni Putu Diantariani Nur Hafsia P. P. Dewi P. Suarya Putu Lakustini Cahyaningrum Putut Dewantha Jenar Sri Rahayu Santi Sri Wahjuni Sri Wardani