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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Majalah Farmaseutik Media Ilmu Kesehatan Al-Tamimi Kesmas: Jurnal Ilmu Kesehatan Masyarakat (Journal of Public Health Sciences) Journal of Fundamental and Applied Pharmaceutical Science Jurnal Ilmu Kesehatan Bhakti Setya Medika
Farisya Nurhaeni
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Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOLIK BERBAGAI JENIS SAYURAN SERTA PENENTUAN KANDUNGAN FENOLIK DAN FLAVONOID TOTALNYA Nurhaeni, Farisya; Lestari, Tri; Wahyuono, Subagus; Rohman, Abdul
Media Farmasi: Jurnal Ilmu Farmasi Vol 11, No 2: September 2014
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5961.165 KB) | DOI: 10.12928/mf.v11i2.1876

Abstract

Tumbuh-tumbuhan diketahui kaya antioksidan alami seperti vitamin E, vitamin C, beta karoten dan flavonoid.Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan10 jenis sayuran, Amaranthus lividus L.sensu Thell., Cichorium endivia, Brassica juncea (L.) Czern., Sauropus androgynus (L.) Merr., Ocimum bassilicum, Brassica oleracea var.botrytis  L.,  Brassica oleracea var.botrytis  L. subvar cauliflora DC., Brassica oleracea var.capitata L., Brassica oleracea var.capitata L. forma rubra, Cosmos caudatus H.B.K dan untuk mengetahui seberapa besar kontribusi senyawa fenolik dan flavonoid pada aktivitas antioksidannya. Uji aktivitas antioksidan dilakukandengan metode DPPH (2,2-difenil-1-pikril hidrazil) dengan menggunakan baku pembanding kuersetin. Analisis kandungan fenolik total ditentukan oleh kemampuan sampel untuk mereduksi reagen Folin Ciocalteau.Analisis flavonoid total dilakukan secara spektrofotometri didasarkan adanya kemampuan flavonoid  membentuk kompleks yang berwarna kuning dengan AlCl3 , yang selanjutnya akan bereaksi dengan  NaOH membentuk warna merah muda yang dapat diukur absorbansinya pada panjang gelombang 510 nm. Hasil penelitian menunjukkan ekstrak kenikir (Cosmos caudatus H.B.K.) memiliki aktivitas antioksidan yang paling tinggi dengan nilai IC50 19,49 µg/ml. Hubungan antara aktivitas antioksidan 10 jenis sayuran dengan kandungan fenolik total diperoleh persamaan regresi linear   y = -34,94 x +562,5, r2 = 0,235 , sementara itu hubungan aktivitas antioksidan dengan flavonoid totalnya diperoleh persamaan y = -16,57 + 755,9, r2 = 0,471.Kata kunci : antioksidan, DPPH, sayuran, fenolik total, flavonoid total 
PENGARUH PERENDAMAN AIR JERUK NIPIS TERHADAP KADAR FORMALIN DALAM IKAN ASIN TERI NASI Burhan, Amelia Handayani; Rini, Yuli Puspito; Nurhaeni, Farisya
Media Ilmu Kesehatan Vol 7 No 3: MIK Desember 2018
Publisher : Pusat Penelitian dan Pengabdian kepada Masyarakat FKes Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v7i3.295

Abstract

Background:The use of formalin as a preservative in salted fish is potentially harmful to the human body,for example in the salted anchovy. They are very popular for customers in Traditional Market of Yogyakarta.The acidic compound, like lime water, can reduce theconcentration of formalin.Objective: This study aims to determine the effect of immersion of lime water on formalin concentration insalted anchovy fish.Methods:A total of 25 samples from five traditional markets of Yogyakarta city were tested using formalin kittest. Positive samples were treated with immersion of lime water with some concentration; 20, 40, 60, 80,and 100% (v/v). Determination of formalin concentration was done by acidimetric method using 0.955Nhydrochloride and methyl red indicator.Results:Concentration of formalin before treatment is 1,397%. The content of Formalin after the immersiontreatment of lime water with concentration 20, 40, 60, 80, and 100% (v/v) for 60 minutes was 1.094; 1,015;0.712; 0.426 and 0.283% (w/w).Conclusion:Based on the statistical test can be concluded that there is the influence of the concentration ofimmersion of lime water to formalin concentration in salted anchovy fish. The higher concentration of limewater can decrease formalin until 79.71%. Keywords:Acidimetric formalin,anchovy salted fish,lemon water,traditional market of Yogyakarta
PENGARUH PERENDAMAN AIR JERUK NIPIS TERHADAP KADAR FORMALIN DALAM IKAN ASIN TERI NASI Handayani Burhan, Amelia; Puspito R, Yuli; Nurhaeni, Farisya
MEDIA ILMU KESEHATAN Vol 7 No 3 (2018): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (95.008 KB) | DOI: 10.30989/mik.v7i3.262

Abstract

Background: The use of formalin as a preservative in salted fish is potentially harmful to the human body, for example in the salted anchovy. They are very popular for customers in Traditional Market of Yogyakarta. The acidic compound, like lime water, can reduce the concentration of formalin. Objective: This study aims to determine the effect of immersion of lime water on formalin concentration in salted anchovy fish. Methods: A total of 25 samples from five traditional markets of Yogyakarta city were tested using formalin kit test. Positive samples were treated with immersion of lime water with some concentration; 20, 40, 60, 80, and 100% (v/v). Determination of formalin concentration was done by acidimetric method using 0.955N hydrochloride and methyl red indicator. Results: Concentration of formalin before treatment is 1,397%. The content of Formalin after the immersion treatment of lime water with concentration 20, 40, 60, 80, and 100% (v/v) for 60 minutes was 1.094; 1,015; 0.712; 0.426 and 0.283% (w/w). Conclusion: Based on the statistical test can be concluded that there is the influence of the concentration of immersion of lime water to formalin concentration in salted anchovy fish. The higher concentration of lime water can decrease formalin until 79.71%. Keywords: Acidimetric formalin, anchovy salted fish, lemon water, traditional market of Yogyakarta
AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOLIK BERBAGAI JENIS SAYURAN SERTA PENENTUAN KANDUNGAN FENOLIK DAN FLAVONOID TOTALNYA Farisya Nurhaeni; Tri Lestari; Subagus Wahyuono; Abdul Rohman
Media Farmasi: Jurnal Ilmu Farmasi Vol 11, No 2: September 2014
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5961.165 KB) | DOI: 10.12928/mf.v11i2.1876

Abstract

Tumbuh-tumbuhan diketahui kaya antioksidan alami seperti vitamin E, vitamin C, beta karoten dan flavonoid.Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan10 jenis sayuran, Amaranthus lividus L.sensu Thell., Cichorium endivia, Brassica juncea (L.) Czern., Sauropus androgynus (L.) Merr., Ocimum bassilicum, Brassica oleracea var.botrytis  L.,  Brassica oleracea var.botrytis L. subvar cauliflora DC., Brassica oleracea var.capitata L., Brassica oleracea var.capitata L. forma rubra, Cosmos caudatus H.B.K dan untuk mengetahui seberapa besar kontribusi senyawa fenolik dan flavonoid pada aktivitas antioksidannya. Uji aktivitas antioksidan dilakukandengan metode DPPH (2,2-difenil-1-pikril hidrazil) dengan menggunakan baku pembanding kuersetin. Analisis kandungan fenolik total ditentukan oleh kemampuan sampel untuk mereduksi reagen Folin Ciocalteau. Analisis flavonoid total dilakukan secara spektrofotometri didasarkan adanya kemampuan flavonoid  membentuk kompleks yang berwarna kuning dengan AlCl3 , yang selanjutnya akan bereaksi dengan  NaOH membentuk warna merah muda yang dapat diukur absorbansinya pada panjang gelombang 510 nm. Hasil penelitian menunjukkan ekstrak kenikir (Cosmos caudatus H.B.K.) memiliki aktivitas antioksidan yang paling tinggi dengan nilai IC50 19,49 µg/ml. Hubungan antara aktivitas antioksidan 10 jenis sayuran dengan kandungan fenolik total diperoleh persamaan regresi linear  y = -34,94 x +562,5, r2 = 0,235 , sementara itu hubungan aktivitas antioksidan dengan flavonoid totalnya diperoleh persamaan y = -16,57 + 755,9, r2 = 0,471. 
Skrining Fitokimia dan Uji Aktivitas Antioksidan Pelepah Batang dan Bunga Pisang Kepok (Musa acuminatae, L.) Farisya Nurhaeni
JURNAL ILMU KESEHATAN BHAKTI SETYA MEDIKA Vol. 4 (2019): Jurnal Ilmu Kesehatan Bhakti Setya Medika
Publisher : Politeknik Kesehatan Bhakti Setya Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (254.442 KB) | DOI: 10.56727/bsm.v4i.71

Abstract

One of the natural ingredients whose benefits are not widely known is the stem and flower of the kepok banana (Musa acuminatae, L.). Stems and flowers of the banana are known to contain flavonoid compounds. Most of the flavonoid compounds have antioxidant activity. This study aims to determine the antioxidant activity and to perform phytochemical screening of the stem and flower ethanolic extracts from banana kepok. Simplicia powder from stem and banana flower was extracted by remaceration method using 96% ethanol. The extract was then tested for antioxidant activity by spectrophotometer using the DPPH method (2,2-diphenyl-1-picrylhydrazyl) at a wavelength of 520 nm. The standard compound used for comparison is quercetin. The results showed that the IC50 value for the ethanol extract of the stem was 19,75 µg/ml and the kapok flower of banana was 13,21 µg/ml . The results of phytochemical screening showed that the stem and flower of banana kepok extract contained flavonoid, saponin and polyphenol.
Analisis Penangkapan Radikal Bebas Jamu Rosella dan Fenolik Totalnya Nurhaeni, Farisya; Purwanto, Purwanto; Irianto, Iramie Duma Kencana; Fiqoh, Latifah Nisa; Ardiyanti, Febriana
Majalah Farmaseutik Vol 20, No 2 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v20i2.92578

Abstract

Dengan semakin berkembangnya tingkat aktivitas manusia, semakin tinggi pula prevalensi penyakit-penyakit yang diakibatkan oleh radikal bebas, yang salah satunya disebabkan oleh pola hidup dan polusi yang ada. Untuk menanggulangi radikal bebas tersebut diperlukan antioksidan, yang mana salah satu sumber utamanya adalah dari tanaman herbal. Guna meningkatkan pemanfaatan herbal tersebut, pembuatan sediaan seperti jamu adalah diperlukan karena sediaan ini yang banyak diminati masyarakat. Dalam penelitian ini, herbal seperti bunga rosella, rimpang kunyit, rimpang jahe, sereh, dan jeruk nipis dipilih sebagai bahan jamu godhog yang kaya akan antioksidan. Dalam hal sebagai sediaan jamu, produk ini terbukti cukup aktif dapat menangkap radikal bebas dengan reagen DPPH. Kandungan fenolik dan flavonoid dalam sediaan jamu tersebut adalah komponen utama yang bertanggung jawab terhadap aktivitas penangkapan radikal bebasnya.
Pengaruh Variasi Bobot Gula Terhadap Kadar Vitamin C pada Puding Bunga Rosela dan Uji Hedonik Burhan, Amelia Handayani; Putri, Salsabilla Surya; Rini, Yuli Puspito; Nurhaeni, Farisya
JURNAL ILMU KESEHATAN BHAKTI SETYA MEDIKA Vol 9 No 1 (2024): Jurnal Ilmu Kesehatan Bhakti Setya Medika
Publisher : Politeknik Kesehatan Bhakti Setya Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56727/8ncdrn17

Abstract

Pudding is a popular snack often consumed as a dessert and enjoyed by people from various backgrounds. One of its variations is Roselle Flower Pudding, which uses roselle petals as the main ingredient. Roselle flowers are known for their high nutritional content, particularly vitamin C, which ranges from 260 to 280 mg per 100 grams. In pudding preparation, sugar is typically added to enhance flavor. However, sugar addition is suspected to affect the vitamin C content and consumer preference for the final product. This study aims to determine the effect of varying sugar weights on the vitamin C content and consumer acceptance of Roselle Flower Pudding. The research was conducted using a true experimental method, utilizing roselle flowers randomly selected from Argomulyo Subdistrict, Sedayu, Bantul. The process included identifying the roselle flower type, making pudding with sugar additions of 0, 5, 10, 15, and 20 grams, testing the vitamin C content using the iodimetric method (0.001 N titration), and conducting a preference test based on taste, aroma, color, and texture. The results showed that increasing sugar levels led to a decrease in vitamin C content: 2.52; 2.37; 2.22; 2.18; and 2.16 mg/100 grams. Conversely, consumer acceptance increased: 63.7%; 64.3%; 69.9%; 72.0%; and 76.8%. The best formulation was with 10 grams of sugar, as it maintained a relatively high vitamin C level while achieving optimal consumer preference.
POTENSI EKSTRAK BUNGA PISANG KEPOK (MUSA PARADISIACA L.) SEBAGAI ANTIOKSIDAN DENGAN METODE DPPH (1,1-DIFENIL-2-PIKRILHIDRAZIL) Farisya Nurhaeni; Amelia Handayani Burhan; Fydika Nurul Riani Sumarjo; Aditya Fitriasari
Al Tamimi Kesmas: Jurnal Ilmu Kesehatan Masyarakat (Journal of Public Health Sciences) Vol 14 No 1 (2025): Al-Tamimi Kesmas: Jurnal Ilmu Kesehatan Masyarakat (Journal of Public Health Sci
Publisher : Institut Kesehatan dan Teknologi Al Insyirah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35328/kesmas.v14i1.2917

Abstract

Kepok banana flower has potential as an antioxidant so it can inhibit free radical activity. Previous research stated that banana flower extract (Musa acuminate) has an IC50 value of 13.21 µg/ml, which means it has very strong antioxidant activity. Therefore, a study was carried out to fractionate the ethanol extract of kepok banana flowers and determine the antioxidant activity of each of these fractions. It is hoped that with this research a purer fraction will be obtained to increase the antioxidant activity. Extraction was carried out by maceration using 96% ethanol, while fractionation was carried out by chloroform. Testing the antioxidant activity using the DPPH method with UV-VIS spectrophotometry. The wavelength used is 517 nm. Extraction was carried out on 30 grams of kepok banana flower powder with 96% ethanol solvent so that 1.27 grams of the thick extract was obtained. Fractionation was carried out on 500 mg of ethanol extract from kepok banana flowers which produced 0.21 gram of soluble fraction and 0.28 gram of chloroform insoluble fraction. The results showed that the IC50 values of ethanol extract, soluble fraction and chloroform insoluble fraction of kepok banana flower extract were 26.00 µg/ml, 236.17 µg/ml, and 18.70 µg/ml respectively. It can be concluded that the ethanol extract and chloroform insoluble fraction of kepok banana flowers have very strong antioxidant activity, while the chloroform soluble fraction has weak antioxidant activity.
Formulation and Organoleptic Evaluation of Roselle (Hibiscus sabdariffa) Jamu Godog with Stability and Microbial Quality Assessment Irianto, Iramie Duma Kencana; Purwanto; Nurhaeni, Farisya; Ana Mardiyaningsih; Bangkit Ary Pratama; Fiqoh, Latifah Nisa; Febriana Ardiyanti
Journal of Fundamental and Applied Pharmaceutical Science Vol. 6 No. 1 (2025): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v6i1.22102

Abstract

Jamu is a traditional medicinal preparation proven to have many pharmacological properties and is widely used in Indonesian society. Unfortunately, many people do not like herbal medicine because of its unpleasant taste and odor. This phenomenon has driven much research in modifying the organoleptic parameters of jamu to make it more acceptable to the tongues and noses of consumers while still having a potent effect on health. This study, thus, aimed to formulate a roselle (Hibiscus sabdariffa)-enhanced jamu godog (traditional Indonesian herbal decoction) and evaluate its organoleptic properties, physical stability, and microbial quality. Jamu godog was prepared by sequentially boiling and mixing ground ginger, turmeric, lemongrass, roselle, rock sugar, and lime, with roselle concentrations set at 0%, 0.3%, and 0.6%. Organoleptic attributes and pH stability were assessed before and after storage at 4°C and 25°C for seven days. Microbial contamination was measured via total plate count (TPC) after storage at 4°C for three and seven days. A hedonic test with 40 participants across two age groups evaluated sensory acceptance. Results indicate that the addition of roselle at 0.3% concentration optimized taste and overall acceptability while maintaining pH stability and microbial safety within BPOM standards throughout the storage period. This formulation demonstrates potential as a palatable and microbiologically safe herbal preparation with enhanced consumer acceptance.  
AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOLIK BERBAGAI JENIS SAYURAN SERTA PENENTUAN KANDUNGAN FENOLIK DAN FLAVONOID TOTALNYA Nurhaeni, Farisya; Lestari, Tri; Wahyuono, Subagus; Rohman, Abdul
Media Farmasi: Jurnal Ilmu Farmasi Vol. 11 No. 2: September 2014
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v11i2.1876

Abstract

Tumbuh-tumbuhan diketahui kaya antioksidan alami seperti vitamin E, vitamin C, beta karoten dan flavonoid.Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan10 jenis sayuran, Amaranthus lividus L.sensu Thell., Cichorium endivia, Brassica juncea (L.) Czern., Sauropus androgynus (L.) Merr., Ocimum bassilicum, Brassica oleracea var.botrytis  L.,  Brassica oleracea var.botrytis L. subvar cauliflora DC., Brassica oleracea var.capitata L., Brassica oleracea var.capitata L. forma rubra, Cosmos caudatus H.B.K dan untuk mengetahui seberapa besar kontribusi senyawa fenolik dan flavonoid pada aktivitas antioksidannya. Uji aktivitas antioksidan dilakukandengan metode DPPH (2,2-difenil-1-pikril hidrazil) dengan menggunakan baku pembanding kuersetin. Analisis kandungan fenolik total ditentukan oleh kemampuan sampel untuk mereduksi reagen Folin Ciocalteau. Analisis flavonoid total dilakukan secara spektrofotometri didasarkan adanya kemampuan flavonoid  membentuk kompleks yang berwarna kuning dengan AlCl3 , yang selanjutnya akan bereaksi dengan  NaOH membentuk warna merah muda yang dapat diukur absorbansinya pada panjang gelombang 510 nm. Hasil penelitian menunjukkan ekstrak kenikir (Cosmos caudatus H.B.K.) memiliki aktivitas antioksidan yang paling tinggi dengan nilai IC50 19,49 µg/ml. Hubungan antara aktivitas antioksidan 10 jenis sayuran dengan kandungan fenolik total diperoleh persamaan regresi linear  y = -34,94 x +562,5, r2 = 0,235 , sementara itu hubungan aktivitas antioksidan dengan flavonoid totalnya diperoleh persamaan y = -16,57 + 755,9, r2 = 0,471. 
Co-Authors Abdul Rohman Aditya Fitriasari Ali Djamhuri Ana Mardiyaningsih Ardiyanti, Febriana Bangkit Ary Pratama burhan, Amelia handayani Febriana Ardiyanti Fiqoh, Latifah Nisa Fydika Nurul Riani Sumarjo Iramie Duma Kencana Irianto Nur Ismiyati Purwanto Puspito R, Yuli Putri, Salsabilla Surya Rony, Zahara Tussoleha SATRIYAS ILYAS Subagus Wahyuono Subagus Wahyuono Tri Lestari Tri Lestari Yuli Puspito Rini, Yuli Puspito