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The decreasing activity of white tea and green tea on smokers lipids profile Rosyanne Kushargina; Rimbawan Rimbawan; Budi Setiawan; Dadan Rohdiana
Jurnal Penelitian Teh dan Kina Vol 18 No 1 (2015)
Publisher : Research Institute for Tea and Cinchona

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22302/pptk.jur.jptk.v18i1.68

Abstract

Smoking habit have many negative effect, including increased lipids profile. Researching on the effects of tea on lipids profile on smokers has been carried out using green tea. Research using white tea has been limited, therefore, this study aimed to analyze the effect of white tea than green tea on lipids profile in smokers, using paired sample of clinical trials design. The subjects were medium smokers (11-21 cigarettes/day) aged 30-45 years and have milddyslipidemia. Each subject was asked to drink tea in two times. Firstly, all subjects were asked to drink 3 x 200 ml white tea/day for 28 days. Secondly, treatment will be start after two weeks washout period, and they were asked to drink 3 x 200 ml of green tea/day for 28 days. Lipids profile (trigliserida (TG); cholesterol total (TC); low density lipoprotein-cholesterol (LDL-C)) of blood serum has been measured four times, at pre-post intervention of white tea and at pre-post intervention of green tea. The lipids profile were significantly decreased after white tea intervention (paired sample t-test, p<0,05). After green tea intervention,the lipids profile were decreased but significant (paired sample t-test, p<0,05) only for LDL-C. The independent sample t-test analysis showed that white tea has higher effect in decreasing the lipids profile greater than green tea, however not significantly different (p>0,05). This study was proved that white tea is more potential than green tea to decreasing lipids profile of smokers.
A Narrative Review of Known Plants which Have Potential Benefits as Natural Galactagogues in Indonesia Winata, Grace Marlina; Hardinsyah Hardinsyah; Sri Anna Marliyati; Rimbawan Rimbawan; Dimas Andrianto
Media Gizi Indonesia Vol. 19 No. 1 (2024): MEDIA GIZI INDONESIA (NATIONAL NUTRITION JOURNAL)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v19i1.57-72

Abstract

Human milk is the gold standard for infant nutrition during the first six months of life. According to Indonesia Demographic and Health Survey in 2017, about 45% of mothers in Indonesia provided pre-lacteal feeding within three days postpartum. Low or no milk production and perceived insufficient milk for the infants need were common reasons for pre-lacteal feeding. Galactagogues are believed to help augment human milk production. Therefore, galactagogue consumption is highly recommended, especially natural galactagogue, to help overcome low milk production problem. Most natural galactagogues are used as a local tradition only. Scientific studies regarding the phytochemical compounds and the mechanisms involved are still very limited. This narrative review aimed to describe selected research articles reporting the potency of torbangun, katuk, kelor, and papaya leaves as known plants acting as natural galactagogues in Indonesia. A total of 22 original research articles from Indonesia written in Indonesian or English over a 20 years period were included in this review. Studies were selected if selected natural galactagogues were evaluated at least for the proposed mechanism of action and effects. The data have shown strong evidence about the positive effect of torbangun, katuk, kelor, and papaya leaves as natural galactagogues on increasing human milk production. The five leaves contain different phytoestrogens that have an estrogen effect to stimulate prolactin production and increase milk production. 
CONSUMPTION OF CARBONATED BEVERAGES AND THE RISK FOR GASTROINTESTINAL DISEASE: A SYSTEMATIC REVIEW Puspo Edi Giriwono; Nuri Andarwulan; Rimbawan Rimbawan; Deddy Muchtadi
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 37 No. 1 (2014)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v37i1.4010.69-76

Abstract

ABSTRACTIssues of different effects of carbonated soft drinks to human health have been circulated and analyzed in both scientific and non-scientific approaches. However, there is few publications discussing the specific effect of carbonation on human health and, more often than not, studies have largely concentrated on the effect of sugar or calorie content in carbonated beverages in affecting our health. Thus the effect of carbonation itself on human health is then lost in arguments contradicting or reaffirming the effect of carbonated soft drinks. We conducted this systematic review to specifically observe current findings on the effect of carbonation in beverages on human health. This systematic review was conducted using Scirus search engine to list articles relevant with keywords such as CO2, carbonated beverage, carbonation, sparkling water, gastrointestinal, gastro-esophageal and adenocarcinoma. Next, articles were obtained from numerous databases and screened for their relevance and context. Finally, peer reading and discussion were conducted for the writing of this article. The results of this systematic review observed three major article subjects currently correlated with exclusive effect of carbonation on gastrointestinal health. Published studies indicate that oral cavity/dental health, gastro-esophageal reflux and most recently esophageal adenocarcinoma are discussed frequently and observed in population studies in different countries consuming significant quantities of carbonated beverages. Eight articles (40%) discussed dominant factors not correlated with carbonation which significantly affect dental erosions. Six (33%) articles observed no clear clinical significance carbonation promotes or exacerbate gastro-esophageal reflux. Interestingly, five (27%) articles reported insignificant correlation, even inversed, of carbonation on esophageal carcinoma.Currently available scientific studies on populations in multiple countries show that the effect of carbonation in beverages has non-significant (statistically) effect on the health of the gastrointestinal tract.Keywords: Carbonated beverages, gastrointestinal, GERD, esophageal adenocarcinoma*ABSTRAKIsu mengenai dampak karbonasi pada minuman ringan terhadap kesehatan, terutama kesehatan saluran pencernaan, telah banyak beredar beserta pembahasannya, baik secara ilmiah maupun tidak. Efek kesehatan dari unsur karbonasi pada minuman ringan sangat jarang dibahas dan dipublikasikan pada jurnal ilmiah. Melakukan systematic review status ilmiah terkini khusus mengenai dampak karbonasi dalam berbagai produk minuman terhadap kesehatan saluran pencernaan. Scirus search engine digunakan untuk melacak artikel ilmiah dengan kata kunci khusus, yakni CO2, carbonated beverage, carbonation, sparkling water, gastrointestinal, gastro-esophageal and adenocarcinoma. Tahap ini dilanjutkan dengan penapisan (screening) untuk kesesuaian subjek artikel dan akses. Tahap terakhir adalah focus group discussion bersama peer/ahli dalam bidang gizi, kesehatan dan keamanan pangan. Hasil dari systematic review memperlihatkan bahwa terdapat tiga kelompok pembahasan utama yang berhubungan dengan efek karbonasi terhadap kesehatan saluran pencernaan, yaitu kesehatan pada gigi/rongga mulut, refluks esofagus dan kanker esofagus. Hasil skrining menunjukkan 40 persen published articles membahas dental health, 33 persen membahas gastro-oestrophageal health dan 27 persen membahas esophageal adenocarcinoma. Delapan artikel yang membahas dental health menunjukkan erosi yang dapat terjadi disebabkan oleh faktor lain di luar karbonasi. Enam artikel yang membahas gastro-oestrophageal health menunjukkan tidak ada korelasi antara faktor karbonasi dengan refluks ataupun refluks kronis yang terjadi. Sementara 5 artikel memperlihatkan observasi yang berkorelasi terbalik dengan risiko munculnya kanker esofagus. Systematic review menunjukkan bahwa saat ini berbagai artikel ilmiah relevan yang sudah dipublikasikan menyimpulkan dampak karbonasi pada minuman terhadap kesehatan saluran pencernaan tidak signifikan secara statistik klinis. [Penel Gizi Makan 2014, 37(1): 69-76]Kata kunci: Minuman berkarbonasi, penyakit saluran pencernaan, GERD, esophageal adenocarcinoma
EFEK PEMBERIAN GULA KELAPA YANG DIPERKAYA MINYAK SAWIT MERAH TERHADAP PENINGKATAN BERAT BADAN DAN KADAR RETINOL SERUM TIKUS DEFISIEN VITAMIN A (EFFECT OF THE FEEDING OF BROWN SUGAR ENRICHED WITH RED PALM OIL ON BODY WEIGHT GAIN AND SERUM RETINOL LEVELS Hidayah Dwiyanti; Hadi Riyadi; Rimbawan Rimbawan; Evy Damayanthi; Ahmad Sulaeman; Ekowati Handharyani
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 36 No. 1 (2013)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v36i1.3397.73-81

Abstract

ABSTRACT Vitamin A deficiency (VAD) is an important cause of blindness and premature death. Vitamin A also plays an important role on growth and immune function.  Red palm oil is the richest naturally occurring source of β-carotene, a carotenoid that the human body can convert into usable vitamin A (retinol). This research was to evaluate the effect of feeding red palm oil enriched brown sugar on improving body weight and serum retinol level of vitamin A depletion Sprague-Dawley rats. Twenty four of six weeks old-male Sprague Dawley rats were used. After 2 weeks of adaptation period, rats were given vitamin A deficient diet (modified  AIN-93M) for 10 weeks, and then divided into 3 groups and received for 2 weeks the different treatment as repletion period: 1) RPO group which received red palm oil enriched brown sugar (1.5 mL/d), 2) CPO group which received crude palm oil enriched brown sugar (1.5 mL/d) and 3) and RE group which received retinyl palmitate (0.6 mL/d) . Each treatment contains approximately 40 µg beta carotene/day. Intervention by feeding brown sugar enriched with RPO and CPO for 2 weeks can increase the body weight of rats by 3.54 percent and 5.23 percent, respectively, which is markedly better than the group that was given retynil palmitat (9.38%) (p<0.05). However, an increase in serum retinol concentrations in all group showed no significant differences (p>0.05). Consumption of brown sugar enriched with RPO or CPO enhances body weight and serum retinol concentration of vitamin A deficient rats. Keywords: brown sugar, red palm oil, serum retinol, vitamin A deficiency, rats  ABSTRAK Kurang vitamin A (KVA) merupakan penyebab utama kebutaan dan kematian dini.  Vitamin A juga berperan pada perkembangan dan fungsi imun.  Minyak sawit merah merupakan sumber β-karoten, dimana tubuh dapat merubahnya menjadi retinol.  Tujuan penelitian untuk mengevaluasi efek pemberian gula kelapa yang diperkaya minyak sawit merah terhadap peningkatan berat badan dan kadar serum retinol tikus Sprague-Dawley defisien vitamin A.  Digunakan 24 ekor tikus jantan usia 6 minggu.  Setelah 2 minggu masa adaptasi, tikus diberi diet bebas vitamin A selama 10 minggu, selanjutnya dibagi menjadi 3 kelompok, yaitu 1) RPO, menerima larutan gula yang diperkaya dengan RPO (1,5 ml/hari), 2) CPO, menerima larutan gula yang diperkaya CPO (1,5 ml/hari)), dan 3) RE, yaitu kelompok yang mendapatkan retynil palmitat dalam minyak sebagai kelompok kontrol positif (0,6 ml/hari). Masing-masing perlakuan mengandung beta karoten setara 7 RE per hari.  Intervensi selama 2 minggu dengan memberikan gula kelapa yang diperkaya RPO maupun CPO mampu  meningkatkan berat badan tikus masing-masing 3,54 persen dan 5,23 persen yang secara nyata lebih baik  dibandingkan kelompok yang diberi retynil palmitat (-9,38%) (p<0,05). Disisi lain, peningkatan konsentrasi serum retinol pada semua kelompok tidak menunjukkan perbedaan yang nyata (p>0,05).  Konsumsi gula kelapa yang diperkaya RPO maupun CPO meningkatkan berat badan dan memperbaiki konsentrasi serum retinol tikus defisien vitamin A. [Penel Gizi Makan 2013, 36(1):73-81] Kata kunci: gula kelapa, sawit merah, retinol serum, defisiensi vitamin A, tikus
ABSORPSI β-KAROTEN SERBUK DAUN SINGKONG (Manihot Utilissima) KERING PADA ANAK PRASEKOLAH Almasyhuri Almasyhuri; M. Khumaidi; Muhilal Muhilal; Rimbawan Rimbawan
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) JILID 20 (1997)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v0i0.2369.

Abstract

Indonesia telah bebas dari masalah kurang vitamin A (KVA), tetapi jumlah anak balita dengan vitamin A serum marjinal (<20 ug/dl) masih tinggi. Salah satu program penanggulangan KVA di Indonesia adalah dengan peningkatan konsumsi sayuran hijau pada anak balita. Menurut de Pee, karoten sayuran hijau kurang dapat diabsorpsi karena berupa ikatan komplek yang kuat yang berada dalam kloro plas. Penelitian ini mempelajari pengaruh pembuatan serbuk kering daun singkong muda dan tua terhadap absorpsi β-karoten pada anak prasekolah. Penelitian dilakukan di Kotamadya Bogor, Jawa Barat. Daun singkong diberikan dalam bentuk masakan gulai, yang diberikan dalam diit makanan pagi, siang dan sore selama tiga hari. Kadar β-karoten dalam duplikat makanan yang dikonsumsi dan dalam tinja selama tiga hari dianalisis dengan HPLC. β-karoten yang diabsorpsi merupakan selisih β-karoten dalam duplikat makanan yang dikonsumsi dan β-karoten dalam tinja selama tiga hari. Absorpsi β-karoten serbuk daun singkong muda kering (DSMK) paling tinggi (37.9±5.2%) dibanding β-karoten serbuk daun singkong tua kering (DSTK) maupun daun singkong muda segar (DSMB) yang besarnya masing-masing adalah 36.8±9.2% dan 35.4±5.8%. β-karoten daun singkong muda segar (DSMB) paling kecil absorpsinya. Tetapi hasil uji anova β-karoten dari ketiga jenis daun singkong tersebut tidak ada perbedaan nyata (p>0.05). Kesimpulan dari penelitian ini ternyata pengeringan dan penghancuran menjadi serbuk belum dapat memperbaiki absorpsi β-karoten yang dikandung dalam daun singkong.