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UJI EFEKTIVITAS SEDIAAN GEL MINYAK ATSIRI KULIT BUAH JERUK PONTIANAK (Citrus nobilis Lour. Var. microcarpa) TERHADAP Escherichia coli DAN Staphylococcus aureus Taurina, Wintari; Rafikasari, Rafikasari
Majalah Obat Tradisional Vol 19, No 2 (2014)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (828.018 KB) | DOI: 10.14499/mot-TradMedJ19iss2pp70-73

Abstract

Minyak atsiri adalah suatu substansi alami yang telah dikenal memiliki aktivitas antibakteri. Penelitian ini bertujuan untuk melihat efektivitas sediaan gel antiseptik minyak atsiri kulit buah jeruk Pontianak. Minyak atsiri kulit buah jeruk Pontianak kemudian diformulasikan menjadi sediaan gel, kemudian diuji efektivitas sebagai antibakteri pada bakteri Escherichia coli dan Staphylococcus aureus.Berdasarkan hasil penelitian, konsentrasi minyak atsiri yang efektif menghambat adalah sebesar 0,5 % terhadap bakteri Escherichia coli, sedangkan Staphylococcus aureus dihambat pada konsentrasi 0,1 %; 0,3 % dan 0,5 %. Hasil dari stabilitas sediaan gelnya menunjukkan bahwa gel memiliki homogenitas, nilai pH dan daya lekat yang stabil. Daya sebar gel meningkat selama 30 hari penyimpanan. Uji analisis One Way Anova menunjukkan bahwa daya sebar setiap formula gel tidak berbeda signifikan.
Efektivitas Gel Anti Jerawat Ekstrak Etanol Rimpang Jahe Merah (Zingiber officinale Rosc. Var. Rubrum) terhadap Propionibacterium acnes dan Staphylococcus epidermidis SYF. OCTY NOVY FISSY; RAFIKA SARI; LIZA PRATIWI
JURNAL ILMU KEFARMASIAN INDONESIA Vol 12 No 2 (2014): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (675.087 KB)

Abstract

Acne can be caused by bacteria, such as Propionibacterium acnes and Staphylococcus epidermidis. Red ginger (Zingiber officinale Rosc. var. rubrum) has been studied for its antibacterial activity. The aims of this research was to determine the minimum inhibitory concentration of red ginger rhizome ethanol extract against P. acnes and S. epidermidis bacteria and the effectiveness when the extraxt formulated into gel. The simplicia was extracted by soxhlet using 96% ethanol. Diffusion method was used to measure the minimum inhibitory concentration (MIC) of extract. Afterwards, the extract was forrmulated into gel by using three variation of HPMC 4000 and carbopol 934 as gel base with ratio of 70:30 (Formula I), 50:50 (Formula II) and 30:70 (Formula III). Gel evaluation included organoleptic, spreadability, adhesive property, pH and antibacterial effectiveness. The data was analyzed by R-Commander program 2.14.1 Version. The results showed MIC values are 0.45% against P. acnes and 0.5% against S.epidermidis. The results of evaluation for 30 days of storage showed that the gels had stable pH and adhesion, homogenous, whereas the spreadablity of gels increased. Antibacterial evaluation showed that formula I give the best effectiveness with 16,11 mm zone of inhibition against P. acnes and 14,00 mm against S.epidermidis.
Pengolahan Ampas Kopi Arabika (Coffea arabica L.) menjadi Masker Face Pack Powder di Desa Punggur Besar, Kuburaya: Processing of Arabica Coffee Dregs (Coffea arabica L.) into Face Pack Powder Masks in Punggur Besar Village, Kuburaya Liza Pratiwi; Pratiwi Apridamayanti; Rafika Sari
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 8 No. 2 (2023): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v8i2.4230

Abstract

Cosmetics are preparations that are popularly used. Face pack is claimed to rejuvenate the skin and remove dirt and excess oil on the skin. Coffee grounds in Punggur Besar Village have only been thrown away and become waste, so a new breakthrough is needed to process coffee grounds so that they can be utilized and not wasted. This PKM activity will be carried out offline using the Health protocol. The purpose of the Community Service Program (PKM) is product innovation by utilizing coffee grounds waste into masks. This PKM activity began with making masks in the laboratory, training activities for making coffee grounds face packs including exposure of material on cosmetic face pack powder treatments, training with health protocols with the number of participants limited to 20 people with a room capacity of 50 people, exposure on labels and face packaging. pack powder, discussion and question and answer. Evaluation and monitoring activities are carried out using a questionnaire (pretest and post-test). The results of the activity showed significant differences in the results of the questionnaire analysis before and after the activity on each question item. The PKM activity targeting PKK women in Punggur Besar Village succeeded in increasing the ability of PKK women in utilizing coffee grounds waste into face pack powder masks. The next activity is expected to be able to provide assistance so that the resulting product obtains a distribution permit so that the coffee grounds face pack powder product can be marketed with a wider market share.
Chemical Screening and Antioxidant Activity of Ethyl Acetate Fraction and Residue from Lansium domesticum Ethanolic Extract Pratiwi Apridamayanti; Rafika Sari
Borneo Journal of Pharmacy Vol. 6 No. 1 (2023): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v6i1.3867

Abstract

Langsat (Lansium domesticum) is a plant that thrives in the tropics. The search for photoprotective compounds derived from natural ingredients has been intensively conducted to develop cosmetic formulations to obtain safe and protective products against UV rays. This study aims to identify chemical compounds in the ethyl acetate fraction and residues of ethanol extract from L. domesticum bark using tube and gas chromatography-mass spectrophotometry tests. At the same time, the antioxidant activity and SPF values were assessed with the DPPH and FRAP methods. The qualitative GC-MS test obtained the percentage peak value and molecular weight. Furthermore, the antioxidant activity was tested using the compound DPPH measured with an ELISA reader at a wavelength of 515.5 nm with UV/vis spectrophotometer and FRAP method using FeCl3 and TPTZ compounds at 615 nm. The SPF value was assessed using Mansur's formula with UV/Vis spectrophotometer at 290 to 320 nm. The results obtained in the ethyl acetate fraction showed terpenoids, while the residue contains phenolics, flavonoids, tannins, and saponins. The GC-MS tests found that the ethyl acetate fraction had 47 types of chemical compounds, including terpenoids and fatty acids group; in the residue, four classes were found, with terpenoid and fatty acid groups being more predominant. Based on the results, the ethyl acetate fraction has an IC50 value of 341.25±26.45 µg/ml and 436.3±10.8 µg/ml; the residue was 94.72±34.22 µg/ml and 2602.79±11.8 µg/ml. Additionally, the SPF values ​​for both were 2.87 and 3.9.
CEMARAN BAKTERI Eschericia coli DALAM BEBERAPA MAKANAN LAUT YANG BEREDAR DI PASAR TRADISIONAL KOTA PONTIANAK Rafika Sari; Pratiwi Apridamayanti
Kartika : Jurnal Ilmiah Farmasi Vol 2 No 2 (2014)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v2i2.28

Abstract

Makanan laut merupakan salah satu jenis makanan yang banyak dikonsumsi oleh masyarakat selain sebagai komoditi ekspor. Tingginya kandungan protein dan air serta pH-nya yang mendekati netral menjadikannya media yang cocok untuk pertumbuhan bakteri sehingga menyebabkan makanan laut cepat mengalami proses pembusukan. Mengkonsumsi makanan laut yang telah terkontaminasi bakteri hidup atau toksin yang dihasilkannya dapat menyebabkan keracunan makanan. Tujuan penelitian ini adalah untuk mengetahui adanya kontaminasi bakteri koliform E.coli sebagai indikator pencemaran pada makanan laut dan memberikan informasi kelayakan dan keamanan konsumsi dari makanan laut di dua pasar tradisional terbesar di daerah Pontianak.  Sampel yang digunakan adalah ikan, sotong dan udang. Penelitian terhadap sampel dilakukan menggunakan uji Most Probable Number (MPN) yang dilengkapi dengan uji biokimia untuk mengidentifikasi jenis bakteri pada sampel melalui penanaman bakteri pada media agar Lactose Broth (LB) dan Briliant Green Lactose Bile Broth (BGLB). Hasil penelitian menunjukkan bakteri koliform E.coli terdeteksi pada 100% sampel dengan nilai MPN  yang tidak memenuhi kriteria kelayakan konsumsi, yakni >3/g, dengan nilai paling terbesar dimiliki oleh sampel sotong yang dijual di kedua pasar tradisional, yakni 220/g. Hasil uji biokimia menunjukkan sampel positif mengandung E.coli dengan terbentuknya cincin berwarna merah pada media uji.
AnaIisis Pengaruh Kebijakan Dividen Terhadap FIuktuasi Harga Saham (Studi Kasus: Pada PT Sekar Laut Tbk di Bursa Efek Indonesia) Ryketeng, Masdar; Musdalifah, Musdalifah; Rafikasari, Rafikasari; Mutiara, Sri; Handayani, Astira
Jurnal Ilmiah Akuntansi dan Keuangan Vol 1, No 1 (2022): Februari
Publisher : Universitas Negeri Makassar

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Abstract

The purpose of this writing is to anaIyze the effect of dividend poIicy on the correction of PT. Sekar Laut Tbk on the Indonesian stock market. The data used in this research covers the three year period 2019-2021. The method of anaIysis is simpIe Iinear regression, which determines the reIationship between the dividend per share (X) and the stock price (Y). The research resuIts show that there is a positive reIationship between dividend per share and PT. Sekar Iaut company's share price. However, anaIysis of the correIation coefficient (r) obtained at 0.46 indicates a weak or even insignificant reIationship between stock dividends and changes in stock prices. In addition, the resuIts of the anaIysis aIso show that the dividend poIicy onIy affects the voIatiIity of stock prices by 21.16%, whiIe other factors such as economic conditions, poIiticaI stabiIity, banking poIicies, bank interest rates and exchange rates infIuence it. 78.84%. This research iIIustrates that the dividend poIicy of PT. Sekar Laut Tbk has no significant effect on stock prices. Other externaI factors aIso pIay an important roIe in stock price movements. This study can be a basis for companies in considering dividend poIicies according to market situations and externaI factors that affect stock prices.Keywords: Dividend PoIicy, FIuctuations, Stock Prices, and the Indonesian Stock Exchange