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All Journal Journal Borneo Jurnal Pengabdian Masyarakat Journal of Pharmaceutical and Natural Resources
Fery Indradewi Armadany
Universitas Halu Oleo
Computer Science & IT Education Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Ujı aktıvıtas sedıaan granul darı ekstrak etanol daun komba-komba (Chromolaena odorata L.) sebagaı larvasıda Fery Indradewi Armadany; Dian Munasari Solo; Ari Putra Utama; Andi Nafisah Tendri Adjeng
Journal Borneo Vol. 2 No. 2 (2022): Volume 2 Issue 2 tahun 2022
Publisher : Politeknik Kaltara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (356.835 KB) | DOI: 10.57174/jborn.v2i2.45

Abstract

Komba-komba (Chromolaena odorata L.) merupakan salah satu tumbuhan yang dapat digunakan sebagai larvasida alami. Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak daun komba-komba berbunga kuning dan bentuk sediaan granulnya sebagai larvasida. Daun komba-komba diekstraksi secara maserasi menggunakan etanol 96% kemudian didelipidasi menggunakan n-heksan. Ekstrak diidentifikasi metabolit sekundernya melalui skrining fitokimia secara kualitatif mengikuti metode Harborne. Pengujian aktivitas larvasida dilakukan pada ekstrak etanol dan ekstrak etanol terdelipidasi pada konsentrasi 250 ppm, 500 ppm, 1000 ppm dan 2000 ppm untuk mengetahui nilai Lethal Concentration/LC50. Ekstrak diformulasi menjadi sediaan granul menggunakan metode granulasi basah. Hasil skrining fitokimia menunjukkan metabolit sekunder ekstrak etanol daun komba-komba yaitu alkaloid, flavonoid, saponin dan tannin. Uji aktivitas larvasida menunjukkan bahwa ekstrak etanol terdelipidasi memiliki aktivitas lebih baik dibandingkan ekstrak etanol dengan nilai LC50 ekstrak etanol terdelipidasi sebesar 261,6 ppm dan ekstrak etanol sebesar 317,1 ppm. Ekstrak tanol terdelipidasi dengan konsentrasi 1000 ppm ke atas berpotensi untuk dikembangkan dalam bentuk sediaan granul karena memiliki aktivitas larvasida setara dengan kontrol positif (temefos 1000 ppm). Ekstrak etanol terdelipidasi daun komba-komba diformulasikan dalam bentuk sediaan granul menggunakan kombinasi eksipien amilum, PVP dan laktosa. Uji aktivitas larvasida pada granul menunjukkan nilai LC50 sebesar 225,8 ppm.
PENINGKATAN PENGETAHUAN IBU-IBU TENTANG BAHAN BERBAHAYA DALAM KOSMETIK DAN CARA MEMILIH PRODUK AMAN Vica Aspadiah; Fery Indradewi Armadany; Erniyanti Erniyanti; Ratna Ratna; Anawula Mengga; Muhammad Faiz Almath; Wa Ode Musdalifa
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 6 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i6.2674

Abstract

The widespread use of cosmetics among women has increased the risk of exposure to hazardous ingredients due to the circulation of illegal products. This community service activity aimed to improve the knowledge of women in Bungkutoko Village, Nambo District, Kendari City, regarding hazardous substances in cosmetics and how to select safe products. The activity employed a participatory educational approach through lectures, interactive discussions, leaflet distribution, and pretest-posttest evaluations. Twenty participants attended the program. The results showed that before counseling, 70% of participants had a low level of knowledge. After the educational intervention, 70% of participants achieved a good level of knowledge. These findings indicate that the counseling program effectively increased community awareness and understanding regarding the importance of choosing safe and legal cosmetic products.
Innovative Formulation of a Facial Serum Using Avocado Oil (Persea americana Mill.) as a Facial Skin Moisturizer Rahmat Muliadi; Astrid Indalifiany; Fery Indradewi Armadany; Vica Aspadiah; Wa Ode Nur Alidah
Journal of Pharmaceutical and Natural Resources Vol. 2 No. 1 (2026): Journal of Pharmaceutical and Natural Resources
Publisher : Jurusan Farmasi Fakultas Kedokteran Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpnar.v2i1.pp24-32

Abstract

Ultraviolet radiation, temperature, and humidity can cause a reduction in the skin's moisture content, leading to dryness. Therefore, an effective moisturizing preparation is required to maintain skin hydration. Avocado (Persea americana Mill.) oil is known to contain unsaturated fatty acids, vitamins, and antioxidants, making it a potential natural moisturizer. This study aimed to formulate a facial serum utilizing avocado oil as the active ingredient and to evaluate its physical characteristics, stability, and moisturizing activity. An experimental approach was employed, creating four facial serum formulations with avocado oil concentrations of 0%, 5%, 10%, and 15%. The evaluations encompassed organoleptic properties, homogeneity, pH, adhesiveness, spreadability, viscosity, phase separation, and emulsion type. Physical stability was assessed using the cycling test method, and moisturizing activity was evaluated in vitro. The results indicated that all formulations exhibited good physical characteristics, were homogeneous, experienced no phase separation, were oil-in-water (O/W) emulsions, and possessed pH values compatible with the skin's physiological pH. The preparations maintained physical stability following the cycling test. Furthermore, the moisturizing activity tests revealed that an increased concentration of avocado oil enhanced the moisturizing efficacy, with formula F3 (15%) yielding the highest moisture values: 52.830% before the cycling test and 42.970% afterward. Based on these findings, it can be concluded that the avocado oil-based facial serum, particularly formula F3, demonstrates the potential to be developed as a stable, safe, and effective facial skin moisturizer
Co-Authors Anawula Mengga Andi Nafisah Ari Putra Utama Aspadiah, Vica Astrid Indalifiany Dian Munasari Solo Erniyanti Erniyanti Muhammad Faiz Almath RAHMAT MULIADI, RAHMAT Ratna Ratna Wa Ode Musdalifa Wa Ode Nur Alidah