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All Journal Journal Borneo Jurnal Pengabdian Masyarakat Journal of Pharmaceutical and Natural Resources Indonesian Journal of Global Health Research
Fery Indradewi Armadany
Universitas Halu Oleo
Computer Science & IT Education Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Ujı aktıvıtas sedıaan granul darı ekstrak etanol daun komba-komba (Chromolaena odorata L.) sebagaı larvasıda Fery Indradewi Armadany; Dian Munasari Solo; Ari Putra Utama; Andi Nafisah Tendri Adjeng
Journal Borneo Vol. 2 No. 2 (2022): Volume 2 Issue 2 tahun 2022
Publisher : Politeknik Kaltara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (356.835 KB) | DOI: 10.57174/jborn.v2i2.45

Abstract

Komba-komba (Chromolaena odorata L.) merupakan salah satu tumbuhan yang dapat digunakan sebagai larvasida alami. Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak daun komba-komba berbunga kuning dan bentuk sediaan granulnya sebagai larvasida. Daun komba-komba diekstraksi secara maserasi menggunakan etanol 96% kemudian didelipidasi menggunakan n-heksan. Ekstrak diidentifikasi metabolit sekundernya melalui skrining fitokimia secara kualitatif mengikuti metode Harborne. Pengujian aktivitas larvasida dilakukan pada ekstrak etanol dan ekstrak etanol terdelipidasi pada konsentrasi 250 ppm, 500 ppm, 1000 ppm dan 2000 ppm untuk mengetahui nilai Lethal Concentration/LC50. Ekstrak diformulasi menjadi sediaan granul menggunakan metode granulasi basah. Hasil skrining fitokimia menunjukkan metabolit sekunder ekstrak etanol daun komba-komba yaitu alkaloid, flavonoid, saponin dan tannin. Uji aktivitas larvasida menunjukkan bahwa ekstrak etanol terdelipidasi memiliki aktivitas lebih baik dibandingkan ekstrak etanol dengan nilai LC50 ekstrak etanol terdelipidasi sebesar 261,6 ppm dan ekstrak etanol sebesar 317,1 ppm. Ekstrak tanol terdelipidasi dengan konsentrasi 1000 ppm ke atas berpotensi untuk dikembangkan dalam bentuk sediaan granul karena memiliki aktivitas larvasida setara dengan kontrol positif (temefos 1000 ppm). Ekstrak etanol terdelipidasi daun komba-komba diformulasikan dalam bentuk sediaan granul menggunakan kombinasi eksipien amilum, PVP dan laktosa. Uji aktivitas larvasida pada granul menunjukkan nilai LC50 sebesar 225,8 ppm.
PENINGKATAN PENGETAHUAN IBU-IBU TENTANG BAHAN BERBAHAYA DALAM KOSMETIK DAN CARA MEMILIH PRODUK AMAN Vica Aspadiah; Fery Indradewi Armadany; Erniyanti Erniyanti; Ratna Ratna; Anawula Mengga; Muhammad Faiz Almath; Wa Ode Musdalifa
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 6 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i6.2674

Abstract

The widespread use of cosmetics among women has increased the risk of exposure to hazardous ingredients due to the circulation of illegal products. This community service activity aimed to improve the knowledge of women in Bungkutoko Village, Nambo District, Kendari City, regarding hazardous substances in cosmetics and how to select safe products. The activity employed a participatory educational approach through lectures, interactive discussions, leaflet distribution, and pretest-posttest evaluations. Twenty participants attended the program. The results showed that before counseling, 70% of participants had a low level of knowledge. After the educational intervention, 70% of participants achieved a good level of knowledge. These findings indicate that the counseling program effectively increased community awareness and understanding regarding the importance of choosing safe and legal cosmetic products.
Innovative Formulation of a Facial Serum Using Avocado Oil (Persea americana Mill.) as a Facial Skin Moisturizer Rahmat Muliadi; Astrid Indalifiany; Fery Indradewi Armadany; Vica Aspadiah; Wa Ode Nur Alidah
Journal of Pharmaceutical and Natural Resources Vol. 2 No. 1 (2026): Journal of Pharmaceutical and Natural Resources
Publisher : Jurusan Farmasi Fakultas Kedokteran Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpnar.v2i1.pp24-32

Abstract

Ultraviolet radiation, temperature, and humidity can cause a reduction in the skin's moisture content, leading to dryness. Therefore, an effective moisturizing preparation is required to maintain skin hydration. Avocado (Persea americana Mill.) oil is known to contain unsaturated fatty acids, vitamins, and antioxidants, making it a potential natural moisturizer. This study aimed to formulate a facial serum utilizing avocado oil as the active ingredient and to evaluate its physical characteristics, stability, and moisturizing activity. An experimental approach was employed, creating four facial serum formulations with avocado oil concentrations of 0%, 5%, 10%, and 15%. The evaluations encompassed organoleptic properties, homogeneity, pH, adhesiveness, spreadability, viscosity, phase separation, and emulsion type. Physical stability was assessed using the cycling test method, and moisturizing activity was evaluated in vitro. The results indicated that all formulations exhibited good physical characteristics, were homogeneous, experienced no phase separation, were oil-in-water (O/W) emulsions, and possessed pH values compatible with the skin's physiological pH. The preparations maintained physical stability following the cycling test. Furthermore, the moisturizing activity tests revealed that an increased concentration of avocado oil enhanced the moisturizing efficacy, with formula F3 (15%) yielding the highest moisture values: 52.830% before the cycling test and 42.970% afterward. Based on these findings, it can be concluded that the avocado oil-based facial serum, particularly formula F3, demonstrates the potential to be developed as a stable, safe, and effective facial skin moisturizer
The Mediating Role of Purchase Intention between Product Display, Price Perception, and Purchasing Decisions in Retail Pharmacies Wa Ode Mirawanti; Ruslin Ruslin; Asriullah Jabar; Henny Kasmawati; Fery Indradewi Armadany; Adryan Fristiohady
Indonesian Journal of Global Health Research Vol. 8 No. 3 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i3.1129

Abstract

The transformation of retail pharmacies into modern retail environments has intensified competition, making marketing strategies such as product display and pricing increasingly important in influencing consumer purchasing behavior. Objective: This study aims to analyze the effect of product display and price perception on purchasing decisions through purchase intention in modern retail pharmacies. This quantitative study employed a cross-sectional design involving 180 respondents from a modern retail pharmacy (Apotek A) in Kendari City. Data were collected using structured questionnaires selected using purposive sampling from a modern retail pharmacy (Apotek A) in Kendari City. Data were collected through structured questionnaires and analyzed using Partial Least Squares–Structural Equation Modeling (PLS-SEM). Measurement model (outer model) and structural model (inner model) evaluations were conducted to assess validity, reliability, and hypothesis testing. The results indicate that product display and price perception have significant positive effects on purchase intention. Purchase intention, in turn, significantly influences purchasing decisions and mediates the relationship between product display, price perception, and purchasing decisions. All constructs demonstrated adequate validity and reliability. Effective product display and favorable price perception enhance consumers’ purchase intentions, leading to higher purchasing decisions in retail pharmacies. These findings highlight the strategic importance of retail-oriented management practices in modern pharmacies.
DETEKSI DINI DAN EDUKASI PENYAKIT ASAM URAT DI LINGKUNGAN KELURAHAN KAMBU Fery Indradewi Armadany; Mesi Leorita; Rifa'atul Mahmudah; Nur Illyyin Akib; Aisyah Said; Dewa Gede Sandhi Yoga; Dwi Sinta; Fina Mei Sridewi; Intan Permatasari Ali Syadikin; Kadek Riani; Ketut Nesa Sawitri; Nur Alifa Muliatan Ramadhani
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 1 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Januari 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i1.2199

Abstract

The increasing prevalence of gout in Indonesia, particularly among the elderly, emphasizes the importance of community-based education and early detection. This community service activity aimed to improve the knowledge of residents of Kambu Village regarding gout, including its risk factors, clinical symptoms, and preventive measures. The program was conducted by the Pharmacy Profession Study Program of Halu Oleo University in collaboration with the UHO Educational Pharmacy and Mokoau Community Health Center during November–December 2025. The methods applied included pre-test, health education sessions, leaflet distribution, interactive discussions, post-test, and free examinations of blood pressure and uric acid levels. A total of 43 participants were involved. The results indicated a significant improvement in participants’ knowledge, as reflected by an increase in correct response rates from 59% in the pre-test to 98% in the post-test. This activity is expected to contribute to gout prevention and improvement of community health outcomes.
SOSIALISASI DAN EDUKASI PENYAKIT ANEMIA SERTA PENGGUNAAN OBAT TABLET TAMBAH DARAH PADA SISWA-SISWI DI SMAN 8 KENDARI Fery Indradewi Armadany; Astrid Indalifiany; Azzahra Muhareva; Hirona Roman Pabendon; Nuraini Nuraini; Suci Lestari; Yusmin Marifatul Janah
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 7 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Juli 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i7.2818

Abstract

Anemia remains a major global health problem, particularly in developing countries such as Indonesia. Clinically, anemia occurs when hemoglobin levels in the blood fall below normal values, reducing the blood’s ability to transport oxygen to body tissues. Anemia is commonly found among adolescents and is often associated with a lack of knowledge regarding the importance of consuming Iron Supplement Tablets (TTD). This community service activity aimed to improve adherence to Iron Supplement Tablet consumption as an effort to prevent anemia among students of SMAN 8 Kendari. The program involved the distribution of Iron Supplement Tablets and health education using lecture methods supported by visual media, including presentation slides and leaflets. A discussion and question-and-answer session was also conducted to encourage participant engagement and understanding. The results of the activity showed that participants gained a better understanding of anemia, its prevention, and the proper use of Iron Supplement Tablets. In conclusion, the students of SMAN 8 Kendari demonstrated increased knowledge and awareness regarding anemia and the appropriate use of Iron Supplement Tablets, indicating that educational interventions can contribute to anemia prevention among adolescents.
Optimization of Anti-Bacterial Gel from Ethyl Acetate Fraction of Purple Sweet Potato Leaves (Ipomoea Batatas L.) Using Hydroxy Propyl Methyl Cellulose (HPMC) and Testing Its Activity Against Staphylococcus Epidermidis Bacteria Muhamad Luthfid Anando Aly Roza; Fery Indradewi Armadany; Wahyuni Wahyuni; Ruslin Ruslin; Adryan Fristiohady Lubis; Nur Illiyyin Akib
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2075

Abstract

Bacterial infections are a significant global health challenge because they can attack various body tissues and cause illnesses ranging from mild to severe. Staphylococcus epidermidis is a bacterium that often causes various infections. Infection by Staphylococcus epidermidis can slow down the wound healing process and carry the risk of serious complications if not properly managed. This study aims to formulate and optimise an antibacterial gel from the ethyl acetate fraction of purple sweet potato leaves (Ipomoea batatas L.) as a natural alternative for treating skin infections caused by the bacterium Staphylococcus epidermidis. Using the I-optimal mixture design method in Design-Expert software, the optimization analysis was performed by evaluating several responses, including pH, viscosity, spreadability, and adhesion of the gel formulation. The experimental data were fitted to an appropriate polynomial model and analyzed using ANOVA to determine the significance of the model and mixture components. Numerical optimization was then carried out by setting the desired criteria for each response to obtain the optimum formulation. The optimal formulation consisted of 2% HPMC and 13% propylene glycol, with a desirability value of 0.964. The results showed that this formulation met all the criteria for a good and stable gel, including organoleptic properties (semi-solid, brownish-green, characteristic odour, homogeneous), pH (5.81), viscosity (2316.52 cPs), spreadability (6.4 cm), and adhesion time (2.18 seconds). The optimal formulation for an antibacterial gel containing the ethyl acetate fraction of purple sweet potato leaves (Ipomoea batatas L.) was achieved using a 2% HPMC concentration and 13% propylene glycol, with a desirability value of 0.964, , this gel formulation is also effective and falls into the category of being highly potent in inhibiting the growth of Staphylococcus epidermidis, as evidenced by the formation of an inhibition zone of 23 mm.
Formulation and Characterization of A Domperidone Fast-Dissolving Film (FDF) Dosage Form using A Polymer Combination Risnawati Raisu; Suryani Suryani; Asriullah Jabbar; Ari Sartinah; Fery Indradewi Armadany; Nur Illiyyin Akib
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2026

Abstract

Domperidone is a dopamine antagonist antiemetic classified as a BCS Class II drug with low solubility and oral bioavailability due to high first-pass metabolism. One approach to enhancing drug release and absorption is through the development of a Fast Dissolving Film (FDF), a thin film that dissolves rapidly in the oral cavity without water and provides a faster onset of action. FDF formulation is influenced by the choice of polymers; HPMC E15 produces a strong and flexible film, while maltodextrin improves solubility and accelerates disintegration, necessitating optimization of the polymer combination to achieve optimal formulation characteristics. To formulate and characterize a fast-dissolving film (FDF) formulation containing domperidone using a combination of hydrophilic polymers. Domperidone is known to have low oral bioavailability due to high first-pass metabolism; therefore, an alternative drug delivery system is needed to improve the speed of onset and therapeutic efficiency. Formula optimization using Design Expert via the I-optimal mixture design method. The independent variables used were the concentrations of HPMC E15 and maltodextrin as polymers, while the dependent variables included fold strength, thickness, disintegration time, and dissolution time. The FDF formulation was prepared using the solvent casting method and evaluated via organoleptic testing, thickness, fold strength, surface pH, content uniformity, and disintegration time. Results: The combination of HPMC E15 and maltodextrin significantly influenced the physical characteristics and drug release from the FDF formulation. The best mathematical model obtained from the optimization was a quartic model. The resulting optimal formulation met the physical evaluation criteria and demonstrated potential as an effective drug delivery system with rapid disintegration and optimal drug release. The domperidone FDF formulation with a combination of HPMC E15 and maltodextrin was successfully developed and possesses characteristics that meet the requirements, as well as the potential to improve bioavailability and the convenience of oral drug administration.
Characteristics of Starch Isolated from Tofu Residue as A Tablet Excipient using Varying Sodium Hydroxide Concentrations Sumratussaleha Sumratussaleha; Nur Illiyyin Akib; Ari Sartinah; Irnawati Irnawati; Suryani Suryani; Fery Indradewi Armadany
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2071

Abstract

The utilization of tofu dregs as a solid waste source containing starch has not been optimized, despite its potential application as a pharmaceutical excipient. This study aimed to isolate starch from tofu dregs and characterize it according to pharmaceutical grade standards for use as a tablet excipient. Starch isolation was carried out using NaOH solutions at concentrations of 0.1%, 0.2%, and 0.3%. Parameter pharmaceutical grade observed included organoleptic properties, iodine test, pH, moisture content, and ash content, which were evaluated based on the experimental research results and analyzed descriptively. The results showed that the moisture content of the isolated starches was 11.09%, 11.55%, and 11.23%, respectively. The pharmaceutical grade evaluation met the requirements for organoleptic taste, as the starch powder was tasteless, and the iodine test produced a blue coloration. The pH values obtained were 5.94, 5.98, and 6.33. However, the organoleptic parameters related to color and odor, described as brownish-white powder with a characteristic odor, as well as the ash contents of 0.9%, 1.9%, and 1.9%, did not meet the required standards. In conclusion, starch can be successfully isolated from tofu dregs, with the 0.1% NaOH treatment providing the best characteristics and showing potential as an excipient for pharmaceutical tablet formulations.
Co-Authors ,, Suryani Adryan Fristiohady Lubis Aisyah Said Anawula Mengga Andi Nafisah Ari Putra Utama Ari Sartinah Aspadiah, Vica Asriullah Jabar Asriullah Jabbar Astrid Indalifiany Azzahra Muhareva Dewa Gede Sandhi Yoga Dian Munasari Solo Dwi Sinta Erniyanti Erniyanti Fina Mei Sridewi Fristiohady, Adryan Hirona Roman Pabendon Intan Permatasari Ali Syadikin Irnawati Irnawati Kadek Riani Kasmawati, Henny Ketut Nesa Sawitri Mesi Leorita Muhamad Luthfid Anando Aly Roza Muhammad Faiz Almath Nur Alifa Muliatan Ramadhani Nur Illiyyin Akib Nur Illyyin Akib Nuraini, . RAHMAT MULIADI, RAHMAT Ratna Rifa'atul Mahmudah Risnawati Raisu Ruslin Ruslin Suci Lestari Sumratussaleha Sumratussaleha Wa Ode Mirawanti Wa Ode Musdalifa Wa Ode Nur Alidah Wahyuni Wahyuni Yusmin Marifatul Janah