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Aktivitas Antioksidan dan Penetapan Kadar Fenol Total Ekstrak Metanol Dedak Bebeapa Varietas padi (Oryza sativa L.) Sugiat, Dede; Hanani, Endang; Mun’im, Abdul
Majalah Ilmu Kefarmasian Vol. 7, No. 1
Publisher : UI Scholars Hub

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Abstract

Antioxidant has been known to have an important role in the prevention and treatment of diseases. In recent years, many plants have been explored to obtain new antioxidants from natural products. Rice has been known rich in antioxidative compounds. However, there is little attention to the co- or by- products from rice (Oryza sativa) milling plant. One of the products is rice bran. In this study ten varieties of rice bran, which are commonly cultivated varieties in Indonesia were studied their antioxidant activity and total phenolic content. The antioxidant activity was examined by DPPH scavenging assay and total reducing power, while total phenolic content was determined by Folin-Ciocalteu reagent. The results of this study showed that the methanolic extract of IR-64 variety demonstrated the strongest DPPH radical scavenger activity with IC50 350.64 ppm, while in reducing power activity was exhibited by methanolic extract of IR-42 variety. However, the highest total phenolic content (71.85 mg gallic acid equivalent/gram) was found in methanolic extract of OM-4495 rice bran. These result indicated that the methanolic extract of rice bran might potentially be natural antioxidants.
Formulasi Sediaan Granul Mukoadhesif Kombinasi Ekstrak Kulit Batang Mimba (Azadirachta indica A. Juss) dan Kunyit (Curcuma domestica val.) Sutriyo, Sutriyo; Khairunnisya, Khairunnisya; Mun’im, Abdul
Majalah Ilmu Kefarmasian Vol. 8, No. 2
Publisher : UI Scholars Hub

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Abstract

Neem bark (Azadirachta indica A.Juss) and turmeric (Curcuma domestica Val.) extracts have been found posses gastroprotective effect so that they are used in the treatment of gastric ulcer. Administration of combination of both extracts can give synergistic effect so that the administration dose can be reduced. In this research, combination of neem bark and turmeric extracts were formulated as mucoadhesive granules to improve their effectivenesses by increasing the residence time of dosage form in the stomach. Mucoadhesive granules were prepared by wet granulation method in six formulas using HPMC, Carbopol, and combination of HPMC and Carbopol as mucoadhesive polymers. Granules were evaluated for particle size distribution, swelling, mucoadhesive strength with bioadhesive in vitro test and wash off test, and dissolution. Bioadhesive in vitro test showed that all formulas have goodmucoadhesive strength.Wash off test showed that combination of HPMC and Carbopol can improve mucoadhesive strength of formulas. Mucoadhesive strength increased with the increasing of HPMC. The result of this research indicated that formula with combination ofHPMCand Carbopol (2:1) showed best mucoadhesive strength with percentage of mucoadhesion 98.67%in bioadhesive in vitro test and 38.00% in wash off test.
Effect of a Combination of Extract of Centella asiatica L. Leaves and Extract of Green Coffee (Coffea canephora robusta P.) Beans in a Cream Preparation for Grade 1-3 Cellulite and Slimming Primastuti, Riska Febriadne; Wih, Wong Lip; Mun’im, Abdul
Makara Journal of Science Vol. 17, No. 1
Publisher : UI Scholars Hub

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Abstract

An accumulation of fat in the subcutaneous tissue causes cellulite and dimpling on the surface of the skin. Although not related to obesity, obesity worsens cellulite. There are abundant topical anticellulite creams on the market, but the efficacy of these creams has not been scientifically proven. A combination of Centella asiatica L. leaves extract and green coffee (Coffea canephora robusta P.) bean extract in a cream preparation was clinically tested in 30 women for 84 days in the absence of diet and exercise. The descriptive-true experimental before (T-0)-after (T-84) method was used to classify the cellulite (grade 1–3) and to determine the slimming effect. The cellulite appearance and the body circumferences (abdominal and thigh) perimeters were photographed 5cm and 10cm below the navel and below the gluteal fold. The results of before and after the treatment showed that grade 1 cellulite lower (p < 0.000), the measurement of abdominal circumference showed reduction (p < 0.013), but the measurement of both thigh circumference showed insignificantly reduction (p < 0.512). The combination of both extracts reduce cellulite and fat deposits in the abdominal area, making the volunteers look slimmer
Identifikasi Pencemaran Limbah Di Sekitar TPA Antang Makassar Menggunakan Metode Geolistrik Resistivitas Mun’im, Abdul; Sappewali, Sappewali; Wahyuni, Ayusari
Dampak Vol 19, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/dampak.19.1.17-21.2022

Abstract

The data presented in this paper are related to the characterization of a subsurface layer of TPA Antang, Makassar, South Sulawesi. The method used in this study is geo-electrical resistivity Wenner configuration by taking the data 3 lines in each region with lengths 150 m. Data processing used non-linear least square optimization with that of the 2D inversion software Res2Dinv. The results showed that the area was underlain by two layers of lithologic sections. The first layer with a resistivity value of 11.5 - 33.64 Ωm with a thickness ranging from 2-6 meters below the surface (original ground surface), was the sediment resulting from stockpiling dominated by silty sand sediment to sand based on field observation information. The second layer with a resistivity value of 3.02 - 11.5 Ωm with a depth ranging from 2 - 6 meters from the surface. The determination of this layer is based on information on well data and responses which indicate that this layer is swampy sediment, dominant sand ranging from sand alone to silty sand. The very small value of recessivity indicates that this layer is not compact sediment so the pore space between the grains was saturated. This layer is identified as a shallow aquifer. Based on the resistivity value, the fluid that filled this layer was divided into two types of fluids, fluids with a low resistivity value of 3.02 - 5.71 Ωm, it is assumed that the influence of leachate which is electrolytic makes it easy to flow electric current, and fluid with a resistivity value of 5.71 - 11.5 Ωm is a fluid that has not been contaminated with leachate. Keywords: Antang Landfill, geoelectric, groundwater, resistivity, waste ABSTRAKData yang disajikan dalam makalah ini terkait dengan karakterisasi lapisan bawah permukaan TPA Antang, Makassar, Sulawesi Selatan. Metode yang digunakan dalam penelitian ini adalah metode geolistrik resistivitas konfigurasi Wenner dengan mengambil data 3 jalur masing-masing daerah dengan panjang 150 m. Pemrosesan data menggunakan optimasi kuadrat terkecil non-linier dengan perangkat lunak inversi 2D Res2Dinv. Hasil penelitian menunjukkan bahwa daerah tersebut dilatarbelakangi oleh dua lapisan bagian litologi. Lapisan pertama dengan nilai resistivitas 11,5 - 33,64 m dengan ketebalan berkisar antara 2-6 meter di bawah permukaan (original ground surface), merupakan sedimen hasil penimbunan yang didominasi oleh sedimen pasir berlumpur hingga pasir berdasarkan informasi observasi lapangan. Lapisan kedua dengan nilai resistivitas 3,02 – 11,5 m dengan kedalaman berkisar antara 2 – 6 meter dari permukaan. Penentuan lapisan ini berdasarkan informasi data sumur dan respon yang menunjukkan bahwa lapisan ini merupakan sedimen berawa, dominan pasir mulai dari pasir saja sampai pasir berlumpur (silty sand). Nilai resesivitas yang sangat kecil menunjukkan lapisan ini merupakan sedimen yang tidak kompak sehingga ruang pori antar butir jenuh oleh air. Lapisan ini diidentifikasi sebagai akuifer dangkal. Berdasarkan nilai resistivitasnya, fluida yang mengisi lapisan ini terbagi menjadi dua jenis fluida yaitu fluida dengan nilai resistivitas rendah 3,02 – 5,71 m, diduga pengaruh lindi yang bersifat elektrolitik memudahkan aliran arus listrik dan fluida dengan nilai resistivitas 5,71 – 11,5 m merupakan fluida yang belum tercemar lindi. Kata kunci: TPA Antang, geolistrik, air tanah, resistivity, limbah
Uji Aktivitas Penghambatan Tirosinase dan Antioksidan Ekstrak Akar Murbei (Morus alba) dengan Metode Ekstraksi Hijau NADES Sebagai Agen Pencerah Kulit Alishlah, Tanfidz; Mun’im, Abdul; Jufri, Mahdi
JURNAL FARMASI DAN MAKANAN Vol 7 No 2 (2024): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i2.4699

Abstract

Morus alba (mulberry) root contains a secondary metabolite of oxyresveratrol with its potential skin-brightening activity. The application of the green extraction method using Ultrasonic-Assisted Extraction with Natural Deep Eutectic Solution (NADES-UAE) was developed because of its advantages, namely it can increase extract yields, low toxicity profile, reduce extraction time, shorter extraction stages without evaporation, and can be applied directly in topical preparations for cosmetic products. To ensure the potential for skin-brightening activity, some activity tests on mulberry root extract are needed. The purpose of this study was to determine the in vitro skin-brightening activity of mulberry root extract using NADES-UAE method. The method used was an in vitro tyrosinase enzyme inhibition test using a microplate reader and an antioxidant activity test using the DPPH method. The IC50 value of the best mulberry root extract (glycerin: urea 1:3 for 15 minutes) showed tyrosinase inhibition activity was 178.43 μg/mL. While the IC50 value in the best antioxidant activity test was 1392.14 μg/mL. Tyrosinase inhibitory and antioxidant activities in three samples showed the best results having the highest oxyresveratrol content. NADES-UAE mulberry root extract has the potential as a cosmetic preparation for skin lightening and has antioxidant effects for skin health.
Pendampingan Penggunaan Writing Tools dalam Peningkatan Karya Tulis Mahasantri Pondok Pesantren Sunan Drajat Lamongan Ulum, Miftachul; Mun’im, Abdul
Keris: Journal of Community Engagement Vol. 4 No. 2 (2024): KERIS: Journal of Community Engagement
Publisher : Institut Pesantren Sunan Drajat Lamongan, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55352/keris.v4i2.945

Abstract

The activity of mentoring the use of writing tools aims to provide understanding and training to the students of Pondok Pesantren Sunan Drajat in compiling articles and scientific papers. The mentoring method is through workshop activities and practice compiling articles using the writing tools application. The implementation of the assistance was carried out on May 1, 2024 which was attended by 20 mahasantri. The result of the service is the realization of the understanding and ability of the assisted participants in preparing articles using a set of writing tools applications. In conclusion, the participants can use the writing tools application in preparing articles and scientific papers.
Development Strategy for Child-Friendly Cities In Ponorogo Regency the Perspective of Muhammad Umer Chapra Rokamah, Ridho; Roihanah, Rif’ah; Mun’im, Abdul; Wongtanee, Chokchai
El Barka Vol. 5 No. 2 (2022)
Publisher : El-Barka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21154/elbarka.v5i2.5136

Abstract

Introduction/main objective: study this review existing strategies applied in the development of Child-Friendly Cities or Kota Layak Anak (KLA) in the Regency Ponorogo with Muhammad Umer's approach Chapra. Background Problems:Construction of KLA in Ponorogo Regency still has not yet can be embodied because six KLA stages have yet to be implemented in a manner whole a manner maximum. Realization of KLA in the District Ponorogo Becomes interesting research with M. Umer's perspective Chapra because as a figure economist Muslim he has to criticize theory economy conventional (which is also implemented in Ponorogo ), but he is not anti-starch with the theory. Novelty: with the study implementation of KLA in the District Ponorogo through M. Umer's perspective Chapra expected there is a new strategic solution that combines existing development _ conducted with applying the 5 principles of development and 3 principles of the life of M. Umer Chapra. Research Methods: Types study this is a study field with a qualitative approach, while Engineering data collection includes an interview, observation, and documentation. Finding/Results: Based on the results of research already _ carried out, the application of KLA in the District Ponorogo is not yet can be held in a manner maximum because exists various constraints. Conclusion: strategy of the government in realizing the development of KLA uses two approaches, namely top-down and bottom-up. The cause of the KLA not being able to materialize is due to the heavy tractability of the problems, the ability of statute to structure implementation, and variables nonstatutory variables affecting implementation beneficiaries of this program do not yet have a big commitment in realizing this program. Those problems no will appear if in implementation government added five principles of development such as providing benefits to the community, reducing the concentration of wealth, realigning the economic/financial sector, making strategic program plans, as well as apply principles tauhid, khilafah, dan ’adalah.
AKAD PARON PERTANIAN CABE PERSPEKTIF HUKUM EKONOMI ISLAM Mun’im, Abdul
LAN TABUR : Jurnal Ekonomi Syariah Vol. 5 No. 2 (2024): Maret
Publisher : Lembaga Pusat Penelitian dan Pengabdian kepada Masyarakat (LP2M) Institut Agama Islam (IAI) Al-Qodiri Jember, Jawa Timur Indonesia bekerjasama dengan Kopertais Wilayah 4 Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53515/lantabur.2024.5.2.384-394

Abstract

This research aims to describe the implementation of the Muzara'ah agreement in the agricultural sector by farmers in Sumberanyar Village and its impact on improving the welfare of farmers in Sumberanyar Village. The method used in this research is a qualitative method. Researchers collected data using observation, interviews and documentation methods. From the results of his research, it was found that the contract was carried out verbally on the basis of mutual help and trust. The results of this research show that the profit sharing for rice field owners and sharecroppers in Sumberanyar Village, namely Paron profit sharing in Sumberanyar Village, is carried out using a Muzara'ah agreement, where the agreement is made at the beginning, the sharing of the results has been mutually agreed upon, namely every time the harvest and produce chilies in Some sales are then shared between land owners and sharecroppers. With this profit sharing system, farmers and cultivators in Sumberanyar Village both benefit, no one feels disadvantaged. Keywords; Paron contract, Islamic Economic Law
Al-Qawaid Al-Fiqhiyyah Proses Penalaran Induktif dalam Kajian Hukum Islam Mun’im, Abdul
Asy-Syir'ah: Jurnal Ilmu Syari'ah dan Hukum Vol 43 No 2 (2009)
Publisher : UINSunan Kalijaga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/ajish.v43i2.100

Abstract

Tulisan ini hendak mengungkap dan menggambarkan proses penalaran dalam pemikiran hukum Islam yaitu al-qawa'id al-fiqhiyah dengan perspektif induktif. Munculnya al-qawa'id alfiqhiyah dimulai dari kegiatan membuat rincian aturan hukum Islam yang dideduksi dari sumber-sumber wahyu. Teks-teks wahyu adalah pembangkit pertama munculnya upaya membuat norma tentang perilaku (fiqh) dengan sarana metodologi yang disebut usul al-fiqh. Kemudian fiqh berkembang dalam kuantitas demikian besar hingga menjadi sulit untuk menguasainya. Maka muncullah gagasan membuat kristalisasi fiqh dalam bentuk kaidah dalam jumlah yang relatif terbatas yang mempermudah penguasaannya dan lahirlah al-qawa'id al-fiqhiyah, yaitu himpunan dari kaidah-kaidah itu. Sebagaimana hasil induksi yang ditingkat probabilitas kebenarannya memerlukan sandaran teori atau pengetahuan a priori, al-qawa'id al-fiqhiyah juga membutuhkan keabsahan dari sumber wahyu. Karenanya, untuk menyikapi kasus baru dilakukan dengan cara menemukan terlebih dahulu semangat wahyu sebagaimana tercermin di dalam fiqh secara induktif. Semangat itu menjadi kerangka umum pembuatan aturan untuk kasus-kasus baru. al-qawa'id al-fiqhiyah, dengan demikian merupakan rasionalisasi dari kehendak Allah sejauh yang dapat dipahami oleh manusia.
PENANGANAN PEMBIAYAAN MURABAHAHBERMASALAH DI BAITUL MAL WA TAMWIL USAHA GABUNGAN TERPADU (BMT UGT) SIDOGIRI CABANG PEMBANTU (CAPEM) ARJASA JEMBER Mun’im, Abdul; Habibi, Rahmat
Lan Tabur: JURNAL EKONOMI SYARIAH Vol. 7 No. 1 (2025): September
Publisher : LAN TABUR: Jurnal Ekonomi Syariah The Islamic University of KH. Achmad Muzakki Syah Jember, East Java. Jember Jln. Manggar Gebang Poreng 139A Patrang Jember Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53515/lt.v7i1.131

Abstract

Mengingat pada tahun 2025 terjadi sebuah pandemic global yang menyebabkan terjadinya sebuah goncangan perekonomian dan berdampak terhadap lebaga keuangan termasuk BMT UGT Sidogiri Capem Arjasa Jember, dan menyebabkan terjadinya pembiaayan yang bermasalah, sehingga dalam hal ini dirumuskan pokok masalah dalam penelitian ini yakni : 1) Bagaimana Strategi seperti apa yang diambil oleh BMT Ugt Sidogiri Capem Arjasa Tahun 2025?, 2) Apa saja faktor-faktor yang menyebabkan pembiayaan murabahah bermasalah di BMT UGT Sidogiri Capem Arjasa?, 3) Bagaimana Prosedur hukum yang dilakukan oleh BMT Ugt Sidogiri Capem Arjasa Tahun 2025?, 4) Bagaimana Upaya penanganan yang dilakukan untuk mengatasi pembiayaan murabahah bermasalah di BMT Ugt Sidogiri Capem Arjasa Tahun 2025?.Penelitian ini menggunakan desain kualitatif dengan pendekatan deskriptif, karena itu data yang diperlukan dikumpulkan melalui wawancara, observasi dan dokumentasi, sementara analisis yang dipakai adalah deskriptif. Hasil penelitian ini menunjukkan bahwa dalam penanganan pembiayaan murabahah bermasalah di BMT UGT Sidogiri Capem Arjasa tahun 2025, menggunakan strategi sama dengan BMT pada umunya, juga menganalisa faktor-faktor penyebab terjadinya pembiayaan macet, melakukan prosedur hukum serta melakukan beberapa upaya penanganan khusus terkait penanganan pembiayaan yang bermasalah di BMT UGT Sidogiri Capem Arjasa.