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Journal : MEDICINUS

Terapi Probiotik pada Akne Vulgaris Reti Anggraeni; Arie Kusumawardani
MEDICINUS Vol. 34 No. 2 (2021): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (224.003 KB) | DOI: 10.56951/medicinus.v34i2.76

Abstract

Acne vulgaris (AV) is a skin chronic inflammatory disease that affects pilosebaceous unit and results in non-inflammatory abnormalities in the form of open comedones (blackhead) and closed comedones (whitehead) and also inflammatory lesions such as papules, pustules and nodules. Many factors contribute to the pathogenesis of AV including skin microbiomes like Propionibacterium acnes (P. acnes) and Malassezia spp. which is associated through its effect on sebum secretion, comedones formation and inflammatory response. Antibiotic therapy with the target of P. acnes has long been the mainstay of AV therapy where it can actually affect the composition of skin microbiomes. As antibiotic resistance increases, knowledge of skin microbiomes associated with AV becomes very relevant and important to be an alternative basis for AV alternative therapy.
Peran Balneoterapi pada Psoriasis Putri Oktriana Rachman; Budi Eko Prasetyorini; Nathania Amelinda; Fatimah Fitriani; Arie Kusumawardani
MEDICINUS Vol. 35 No. 2 (2022): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (185.252 KB) | DOI: 10.56951/medicinus.v35i2.95

Abstract

Psoriasis is a chronic recurrent inflammatory disease influenced by several risk factors, including genetics, immune system, environment, and hormones. Skin lesions associated with psoriasis are well-defined erythematous plaques covered in thick, layered, white scales. Psoriasis treatment varies according to the severity of the condition and may include topical or systemic medications, light therapy, or natural elements such as minerals and balneotherapy. Balneotherapy may be used in conjunction with other treatments for psoriasis due to its efficacy in healing psoriasis lesions, particularly plaque forms. Balneotherapy is a traditional medicinal treatment that involves bathing, drinking, or inhaling mineral-containing water. Mineral sources include mineral water, mineral mud (peloids), and natural gas from natural springs. Balneotherapy can thin the stratum corneum and lucidum, decrease the number of lymphocytes, histiocytes, granulocytes, and eosinophils, increase skin permeability, decrease inflammation, improve microcirculation and the skin immune system, and decrease pro-inflammatory cytokines in psoriasis. This article aims to explore the efficacy of balneotherapy as adjuvant therapy for psoriasis to accelerate clinical improvement and reduce disease recurrence.