Article Per Year (5 Year)
p-Index From 2020 - 2025
0.61
P-Index
This Author published in this journals
All Journal Makara Journal of Health Research The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Lee, Yeong Yeh
Unknown Affiliation
Medicine & Pharmacology

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Chronic constipation among community-dwelling older people in the East Coast region of Peninsular Malaysia Wahab, Patimah Abdul; Kadir, Azidah Abdul; Lee, Yeong Yeh; Ali, Siti Hawa; Yusoff, Dariah Mohd
Makara Journal of Health Research Vol. 23, No. 3
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: This study aimed to investigate the prevalence, symptoms, and factors associated with chronic constipation among community-dwelling older people in the East Coast region of Peninsular Malaysia. Methods: A cross-sectional study was conducted in four selected health clinics using stratified cluster sampling. A face-to-face interview was carried out among the elderly outpatients, in order to complete a structured questionnaire. Results: A total of 400 participants were included in the study. The mean age was 68.7 ± 6.4 years, and 55% of the cohort were women. The prevalence of chronic constipation was 32.3% among the sample population. The most common symptom was “sensation of incomplete evacuation” (63.6%), and none of the participants reported having “less than three defecations per week,” “straining,” or “lumpy or hard stool.” Educational level (p = 0.005), number of defecations per week, stool form, time spent for defecation, and abdominal bloating were significantly associated with chronic constipation (p < 0.001). Conclusion: Chronic constipation was common in older people and associated with a low educational level. Recognition of symptoms was predominantly based on clinical features of constipation and will require the healthcare providers to consider these factors in their routine assessment of older people.
Urinary Gluten Immunogenic Peptides Correlation with Celiac Disease: A Systematic Review Prasetya, Alver; Yonatan, Eric Ricardo; Subagya, Jonathan Christianto; Tansil, Naomi Juwita; Lee, Yeong Yeh; Tenggara, Riki
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 25, No 2 (2024): VOLUME 25, NUMBER 2, August, 2024
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2522024280

Abstract

ABSTRACTBackground: Celiac disease (CD) is a condition caused by an abnormal immune response to gluten products. The mainstay of treatment is the gluten-free diet (GFD), but despite patients' efforts to avoid gluten products, some inevitably consume gluten. As current methods for monitoring are limited, a better marker is urgently needed. Urinary gluten immunogenic peptide (UGIP) has been shown to correlate with gluten intake and mucosal damage in CD patients. Therefore, the aim of this systematic review is to summarize the evidence on UGIP as a biomarker in CD patients.Method: This systematic review was conducted in accordance with the PRISMA statement guidelines. The literature search was done using PubMed, ProQuest, EBSCOHost, and Google Scholar for relevant journals published up to March 2023. Newcastle Ottawa Scale and Cochrane Risk of Bias were utilized in the quality assessment of the studies. Result: The literature search identified 85 studies. After eliminating irrelevant and duplicated studies, eight studies were included. Detectable UGIP concentration in the urine correlates with the degree of mucosal damage of CD patients (Marsh II-III). Although three observational studies concluded that there is a correlation between gluten intake and UGIP detection, two randomized controlled trials (RCTs) found that UGIP is not reliable for determining adherence to GFD. Furthermore, UGIP concentrations did not correlate with antibody titers and clinical symptoms. Conclusion:  UGIP may be a helpful biomarker for predicting the severity of mucosal damage in CD patients. However, further studies are needed to evaluate its role in predicting adherence to GFD.ABSTRAKLatar belakang: Penyakit Celiac (CD) adalah suatu kondisi yang disebabkan oleh respon imun yang tidak normal terhadap produk gluten. Pengobatan utama adalah dengan diet bebas gluten (GFD). Meskipun pasien berupaya untuk menghindari produk gluten, beberapa pasien dapat secara tidak sengaja mengkonsumsi gluten. Karena pemeriksaan untuk memantau konsumsi gluten masih terbatas, modalitas pemeriksaan yang dapat diandalkan sangat dibutuhkan. Beberapa bukti mengatakan terdapat korelasi antara peptida imunogenik gluten urin (UGIP) dengan asupan gluten serta kerusakan mukosa pada pasien CD. Oleh karena itu, tinjauan sistematis ini bertujuan untuk merangkum bukti tentang UGIP sebagai modalitas pemeriksaan pada pasien CD.Metode: Tinjauan sistematis ini dilakukan sesuai dengan pedoman pernyataan PRISMA. Pencarian literatur dilakukan menggunakan PubMed, ProQuest, EBSCOHost, dan Google Scholar untuk jurnal relevan yang diterbitkan hingga Maret 2023. Newcastle Ottawa Scale dan Cochrane Risk of Bias digunakan dalam penilaian kualitas studi.Hasil: Pencarian literatur mengidentifikasi 85 penelitian. Setelah mengeliminasi studi yang tidak relevan dan duplikat, delapan studi dimasukkan. Konsentrasi UGIP yang terdeteksi dalam urin berkorelasi dengan tingkat kerusakan mukosa pasien CD (Marsh II-III). Meskipun tiga studi observasi menyimpulkan bahwa ada korelasi antara asupan gluten dan deteksi UGIP, dua uji randomized controlled trials (RCT) menemukan bahwa UGIP tidak dapat diandalkan untuk menentukan kepatuhan terhadap GFD. Selain itu, konsentrasi UGIP tidak berkorelasi dengan titer antibodi dan gejala klinis. Kesimpulan: UGIP dapat dipertimbangkan untuk membantu untuk memprediksi tingkat keparahan kerusakan mukosa pada pasien CD. Namun, studi lebih lanjut diperlukan untuk mengevaluasi perannya dalam memprediksi kepatuhan terhadap GFD. 
Prevalence and Determinants of Gastroesophageal Reflux Disease in a Regional Indonesian Hospital Gastroesophageal Reflux Disease: Patterns and Risk Factors in a West Java Hospital Setting Fatimah, Liliana Surya; Wikarta, Dwi Bayu; Lee, Yeong Yeh; Gisrianti, Reina Syafira
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 25, No 2 (2024): VOLUME 25, NUMBER 2, August, 2024
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2522024329

Abstract

Background: Gastroesophageal reflux disease (GERD) is increasing prevalent in Indonesia. However, epidemiology data remain limited, particularly in developing regions such as Karawang. Therefore, this study aims to examine the prevalence, risk factors, and clinical characteristics of GERD within the population of Karawang, West Java.Methods: This study employed a cross-sectional design. Patients aged 18 years who visited the Karawang Regional Public Hospita, were recruited sequentially. Data were collected using a standardized questionnaire. Univariable and multivariable analyses were performed, with a p-value 0.05 considered stastically significant.Results: The prevalence of GERD was 55.6%, with a higher prevalence in women compared to men (58% vs. 42%, p = 0.263). Significant factors associated with GERD included age 40 years (OR = 0.126; 95% CI: 0.043-0.369; p = 0.001), frequent consumption of spicy foods (OR = 5.002; 95% CI: 2.534-9.877; p = 0.001); and NSAIDs consumption (OR = 2.002; 95% CI =2 1.049-3.821; p = 0.035).Conclusion: GERD is prevalent in the Karawang region. Key factors associated with its occurrence include younger age, frequent consumption of spicy foods, and the use NSAIDs.
Probiotics for Preventing Relapse in Ulcerative Colitis: A Systematic Review and Bayesian Network Meta-Analysis Alvianto, Steven; Muzellina, Virly Nanda; Widjanarko, Nicolas Daniel; Lee, Yeong Yeh; Wangidjaja, Olivia
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 26, No 2 (2025): VOLUME 26, NUMBER 2, AGUSTUS, 2025
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2622025130-142

Abstract

Background: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by periods of relapse and remission. Preventing relapse is critical to improving long-term outcomes. This study aimed to compare the efficacy of probiotics, 5-aminosalicylic acid (5-ASA), probiotics combined with 5-ASA, and placebo in preventing relapse in UC.Methods: A comprehensive search from PubMed, Cochrane Library, MEDLINE, ProQuest, ScienceDirect, Clinical Trials. gov and Google Scholar databases were conducted. The primary outcome was clinical relapse. A Bayesian random-effects model calculated pooled odds ratios (ORs) with 95% CIs and treatment ranks were assessed using the surface under the cumulative ranking curve (SUCRA).Results: Of total 552 initial papers, 37 extracted, and 26 were removed due to exclusion criteria. Eleven RCTs involving 1,099 participants were eventually included for analysis. Probiotics combined with 5-ASA had the highest efficacy (OR = 0.23, 95% CI: 0.027–1.09; SUCRA = 71.43), followed by 5-ASA alone (OR = 0.25, 95% CI: 0.035–0.95; SUCRA = 66.90) and probiotics alone (OR = 0.275, 95% CI: 0.059–0.724; SUCRA = 59.69). Placebo ranked lowest (SUCRA = 1.98). The most commonly used probiotics included E. coli Nissle 1917, Lactobacillus GG, and Bifidobacterium species. The most frequently used 5-ASA preparation was mesalazine. Interventions were generally well-tolerated, with no significant adverse events reported. Conclusion: With the Bayesian NMA, Probiotics plus 5-ASA demonstrates the highest efficacy in preventing relapses in UC. Further research is needed to standardize probiotic regimens and to assess long-term outcomes with the combination approach.
Co-Authors Ali, Siti Hawa Alvianto, Steven Fatimah, Liliana Surya Gisrianti, Reina Syafira Kadir, Azidah Abdul Muzellina, Virly Nanda Prasetya, Alver Riki Tenggara Subagya, Jonathan Christianto Tansil, Naomi Juwita Wahab, Patimah Abdul Wangidjaja, Olivia Widjanarko, Nicolas Daniel Wikarta, Dwi Bayu Yonatan, Eric Ricardo Yusoff, Dariah Mohd