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All Journal Majalah Farmaseutik Media Ilmu Kesehatan JURNAL FARMASIMED (JFM) Jurnal Farmasi Sains dan Praktis Journal of Pharmaceutical and Sciences. Borneo Journal of Pharmacy
Chairun Wiedyaningsih
Universitas Gadjah Mada
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Efek Samping Penggunaan Terapi Oral Pada Pasien Asma Heni Lutfiyati; Zullies Ikawati; Chairun Wiedyaningsih
Jurnal Farmasi Sains dan Praktis Vol 1 No 1 (2015)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v1i1.64

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh terapi oral terhadap hasil terapi pasien asma. Penelitian ini merupakan penelitian observasional dengan pengambilan data secara prospektif dari Februari-April 2014. Data diambil dari penelusuran rekam medis, wawancara dan lembar pengumpul data. Pasien yang memenuhi kriteria inklusi sebanyak 75 pasien tetapi hanya 71 pasien yang mengikuti seluruh proses penelitian. Hasil penelitian menunjukkan dari 71 pasien yang mendapat terapi oral sebanyak 19 orang (26,7%) muncul adanya efek samping. Efek samping yang paling banyak dirasakan oleh pasien adalah gastritis atau gangguan pencernaan pada pasien yang mendapat terapi Methylprednisolon, Cetirizin, kapsul (aminofilin, salbutamol dan GG) yaitu 8 pasien (11,3%), dan berdebar sebanyak 3 pasien (4,2%). Pada pasien yang mendapatkan terapi kombinasi Methylprednisolon, Cetirizin, dan salbutamol sebanyak 3 pasien (4,2%) juga mengalami gastristis.
Pengaruh Edukasi Apoteker Pada Swamedikasi Nyeri Terhadap Hasil Terapi dan Kepuasan Terapi Chairun Wiedyaningsih
Majalah Farmaseutik Vol 18, No 4 (2022): in press
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v18i4.68707

Abstract

Apoteker sebagai fasilitator dalam praktik swamedikasi, harus memiliki kompetensi terhadap pemilihan obat, dan pemberian informasi obat yang sesuai dengan kondisi nyeri pasien untuk mencapai tujuan terapi yang diinginkan dan mengurangi kesalahan penggunaan obat. Tujuan dari penelitian ini adalah mengetahui pengaruh edukasi oleh apoteker pada pasien swamedikasi nyeri terhadap hasil terapi dan kepuasan terapi.Penelitian menggunakan rancangan eksperimental posttest control group. Data diperoleh dari kuesioner Visual Analogue Scale (VAS) dan Treatment Satisfaction Questionnaire for Medication (TSQM) untuk menilai hasil terapi dan kepuasan terapi pasien swamedikasi nyeri di salah satu apotek di Yogyakarta periode Agustus 2021. Edukasi yang diberikan berupa edukasi terkait obat oleh Apoteker. Analisis data univariat dilakukan untuk mendapatkan gambaran karakteristik responden. Analisis perbandingan hasil terapi dan kepuasan terapi menggunakan uji Chi-Square.Jumlah sampel yang digunakan yaitu masing-masing 20 responden untuk kelompok edukasi dan kontrol. Responden penelitian ini rata-rata berusia < 60 tahun dan berjenis kelamin perempuan. Nyeri yang paling banyak dirasakan adalah nyeri otot. Analisis hasil terapi berdasarkan tercapainya penurunan nilai VAS sebelum dan sesudah pemberian edukasi, menunjukkan perbedaan bermakna antara kelompok edukasi dan kontrol (p=0,044). Analisis kepuasan terapi TSQM dilakukan dengan membandingkan kelompok edukasi dan kontrol. Analisis perbandingan kepuasan terapi berbeda bermakna pada domain kenyamanan terapi (p=0,047). Edukasi yang diberikan apoteker secara bermakna meningkatkan hasil terapi dan kepuasan terapi domain kenyamanan terapi, namun tidak meningkatkan kepuasan terapi domain efektivitas terapi dan kepuasan global
Kesesuaian pencampuran sediaan obat intra vena di Rumah Sakit PKU Muhammadiyah Wonosari Chairun Wiedyaningsih; Shalahuddin Al Madury; Rina Mutiara
MEDIA ILMU KESEHATAN Vol 12 No 2 (2023): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v12i2.811

Abstract

Background: The process of intravenous admixture preparations is one of the stages that require special attention to not affect the quality of the resulting preparations. An aseptic technique is required to maintain the sterility of the product produced and ensure its safety.Objective: To identify the appropriateness of the implementation of intravenous admixture based on guidelines and other standard relevant.Methods: This research was conducted at PKU Muhammadiyah Wonosari Hospital in the October-November 2022 period with 100 samples of intravenous injection preparations, which were directly observed using a checklist sheet which was then analyzed quantitativelyResults: The percentage of suitability for the preparatory stage was 89% in the appropriate category. Most suitability in the preparation stage is the use of disposable masks, which is 97%. The suitability of the IV admixture preparations in this study was 54%. The highest suitability of each assessment item is the highest at the stage of preparing all equipment and materials on the workbench (100%) and All drugs mixed using a compatible solvent (100%). Conclusion: In the preparation process, most of them are in accordance with the referenced standards, but at the intravenous admixture stage, the evenness is still low, so improvements are needed to improve aseptic techniques
Public Perspective on Hyperlipidemia Drugs and Sentiments About Hyperlipidemia on Twitter Murojil Hasan; Chairun Wiedyaningsih; Nanang Munif Yasin
Borneo Journal of Pharmacy Vol. 6 No. 3 (2023): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v6i3.4936

Abstract

Hyperlipidemia is a non-communicable disease (NCD) caused by several factors, such as a person's socioeconomic status, culture, customs, habits, and lifestyle. Through user interaction on social media, we can discover the model anti-hyperlipidemia by extracting information, complaints, suggestions, and calls for help about the treatment, which will play a role as an intervention to reduce hyperlipidemia in Indonesia. This study aimed to identify factors influencing perceptions of hyperlipidemia drugs and resulting sentiment on the social media platform Twitter. This study used user-uploaded tweet data to compare perceptions of hyperlipidemia drugs in 2020 and keywords for hyperlipidemia terms and medicine. Tweets related to anti-hyperlipidemia were extracted by issuing tweets containing advertisements, news, re-tweet, and content outside of health. The tweet data obtained was then carried out through content analysis, including point of view, theme, and sentiment analysis, to identify whether the resulting tweets are positive, neutral, or negative using the Support Vector Machine (SVM) method. We identified 1572 hyperlipidemia-related tweets and 153 specific tweets describing hyperlipidemia medications. Tweets about anti-hyperlipidemia showed 99 tweets from the first-person perspective, 23 from the second-person perspective, 22 from healthcare professionals, and nine unidentifiable (other). Sixty-three tweets talked about the benefits of lipid-lowering drugs, 17 complaint tweets, 49 suggestion tweets, 17 question tweets, and two side effect tweets. Assessing public perceptions and sentiment toward hyperlipidemia treatment can be used to develop strategies to increase treatment adherence, improve treatment outcomes, and target health promotion efforts.
A Systematic Review of Healthcare Professionals' Knowledge, Attitudes, and Practices Regarding Adverse Drug Reaction Reporting in Southeast Asia Maria Sintia Manek; Chairun Wiedyaningsih; Dwi Endarti
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/c3t2v738

Abstract

Background: Adverse drug reaction (ADR) reporting is a crucial component of ensuring patient safety within a pharmacovigilance system. ADR reporting plays an essential role in detecting, assessing, and preventing adverse effects related to medications in clinical practice. However, ADR reporting practices in Southeast Asia remain low. Objective:  The purpose of this systematic review was to evaluate and synthesize evidence regarding healthcare professionals' knowledge, attitudes, and practices (KAP) regarding ADR reporting in Southeast Asia. This review aims to provide a comprehensive overview of current evidence and identify key gaps that may affect reporting practices. Methods: We conducted a literature search using PubMed, Scopus, EBSCOhost, and Web of Science for studies published between 2015 and 2025. Studies meeting the inclusion criteria were assessed for quality and analyzed using the PRISMA approach. This systematic review examined 16 studies from six Southeast Asian countries. Results: Most healthcare professionals have positive attitudes toward reporting ADRs, but knowledge varies, and actual reporting practices are low. Training, education, and incentive support were the most frequently cited factors facilitating reporting. Time constraints, unavailability of reporting forms, lack of awareness, uncertainty about the causality of drugs with adverse reactions, and lack of incentives were the main barriers to reporting. Conclusion: Healthcare professionals in Southeast Asia generally show positive attitudes toward ADR reporting, but knowledge remains varied, and reporting practices are low. Continuous education, system integration, and stronger national pharmacovigilance policies are needed to improve reporting.
Analysis of Drug Inventory Control in Indonesian Hospitals Using the ABC Critical Index Method: A Systematic Review Santhy Charyani Putri; Satibi; Chairun Wiedyaningsih
Jurnal FARMASIMED (JFM) Vol 9 No 1 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v9i1.3687

Abstract

Background: Drug inventory management in hospitals is very important to ensure the availability of safe and effective drugs, especially within the framework of the National Health Insurance (JKN). The ABC critical index method has been recognized as an efficient strategy for improving drug inventory control. Objective: This study aims to investigate the application of the ABC Critical Index method in drug inventory management in hospitals, as well as to improve the overall quality of health services. Methods: This systematic review followed the PRISMA guidelines and involved a literature search in four databases, namely Garuda, Scopus, SpringerLink, and Google Scholar, using relevant keywords. Of the 169 articles found, eight articles were selected to meet the criteria for further analysis. Results: This review shows that drug inventory control can be improved through the application of the Critical Index ABC analysis method, which groups drugs into categories A, B, and C based on their usage value and contribution to the budget. Category A drugs, despite their small number of items, absorb the largest portion of the budget and therefore require close monitoring. In addition, the study also emphasized the importance of integrated information systems and electronic prescription systems to improve the accuracy of stock monitoring and reduce the risk of stock outs. Several studies also highlighted the benefits of the Economic Order Quantity (EOQ) and Reorder Point (ROP) methods in determining the optimal order quantity and reorder time, which overall contribute to the efficiency of hospital pharmacy logistics. Conclusion: The implementation of the ABC Critical Index method in controlling drug inventory in hospitals can improve operational efficiency and ensure the availability of quality drugs. Cooperation between pharmacists and hospital management is very important to ensure the effectiveness of the control system, which in turn can improve the overall quality of health services.
Faktor-faktor yang Memengaruhi Kepatuhan Pasien terhadap Terapi Antibiotik: Tinjauan Sistematis Rahma Aulia; Chairun Wiedyaningsih; Endang Indriasih
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1818

Abstract

Background: Antimicrobial resistance (AMR) is a critical global health crisis exacerbated by persistent misuse and non-adherence to antibiotic therapies. Because comprehensive evidence detailing the specific factors driving these behaviors remains scarce, this systematic review aimed to identify and synthesize the multifactorial drivers influencing patient adherence and misuse across diverse populations. Method: Following the PRISMA guidelines, a systematic literature search was conducted to screen cross-sectional studies assessing antibiotic adherence, self-medication, and misuse. Eighteen studies met the inclusion criteria for final analysis. The methodological quality of the included studies was independently evaluated by two reviewers utilizing the Joanna Briggs Institute (JBI) Critical Appraisal Checklist for Analytical Cross-Sectional Studies. Result: The review identified complex factors across five domains: sociodemographic, knowledge and beliefs, medication-related, behavioral, and the health system. Lower education, younger age, and financial constraints consistently predicted non-adherence. Knowledge gaps were prevalent, particularly the misconception that antibiotics are effective for viral infections. Therapy-related factors, such as frequent dosing (e.g., three times daily) and long treatment durations, significantly reduced adherence. Behaviorally, premature discontinuation of therapy upon symptom relief was the most common form of non-adherence, leading to the retention of leftover antibiotics. Furthermore, health system factors, including easy access to non-prescription antibiotics and the lack of a regular doctor-patient relationship, facilitated inappropriate use. Conclusion: Patient adherence to antibiotics is influenced by a complex interplay of socioeconomic, cognitive, and structural factors. Effective interventions must be multifaceted, combining public education to correct misconceptions, prescriber-led simplification of treatment regimens, and stricter enforcement of dispensing regulations.
Studi Potong Lintang tentang Pengetahuan, Sikap, dan Praktik terkait Penggunaan dan Resistensi Antibiotik pada Komunitas Indonesia yang Mengalami Urbanisasi Rahma Aulia; Chairun Wiedyaningsih; Endang Indriasih
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1828

Abstract

Background: Antibiotic resistance is a major global health crisis exacerbated by the misuse of and poor adherence to treatments. Evidence on the behavioral factors driving this misuse remains scarce, particularly in rapidly growing urban areas of developing nations. Therefore, this study evaluates the community’s knowledge, attitude, and practices (KAP) regarding antibiotic use in South Tangerang City, Indonesia, aiming to understand the interconnections between these factors and sociodemographic characteristics. Materials and Methods: A cross-sectional survey was conducted using convenience sampling to recruit participants from the Pondok Jagung and Serpong 2 Health Centers. Data were collected via a validated questionnaire. Statistical analyses included descriptive statistics, chi-square tests, multivariate logistic regression, and Spearman’s rho correlation to assess relationships between variables. Results: Among 110 respondents, education level was significantly associated with knowledge regarding antibiotics (p = 0.044). While initial tests indicated gender and employment affected attitudes, multivariate logistic regression confirmed that only gender remained a strong independent predictor (p = 0.019), with men exhibiting significantly lower odds of holding positive attitudes (OR = 0.237). Notably, good knowledge did not automatically translate to better attitudes or practices. Instead, a positive attitude showed a statistically significant but weak correlation with appropriate antibiotic use (r = 0.193, p = 0.043).  Conclusion: A statistically significant but weak positive correlation was found between attitudes and practices (r = 0.193, p = 0.043), suggesting that while attitudes may influence behavior, other unmeasured factors likely play substantial roles. These findings provide essential baseline data for local health centers to design targeted interventions.
Co-Authors Endang Indriasih Heni Lutfiyati Maria Sintia Manek Murojil Hasan Nanang Munif Yasin Rahma Aulia Rina Mutiara Santhy Charyani Putri Satibi Shalahuddin Al Madury, Shalahuddin Al ZULLIES IKAWATI