Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Jurnal Farmasi Sains dan Praktis
Muhammad Ilyas Yusuf
Universitas Halu Oleo, Indonesia
Immunology & microbiology Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
ANTIHYPERURICEMIA ACTIVITY OF WUALAE FRUIT (Etlingera elatior Jack R. M. Smith) ETHANOL EXTRACT IN VIVO Asriullah Jabbar; Wahyuni Wahyuni; Mesi Leorita; Muhammad Ilyas Yusuf; Sahidin Sahidin
Jurnal Farmasi Sains dan Praktis Vol 7 No 3 (2021): Supplementary Issue (The 4th National Pharmacy Conference 2021 Universitas Halu O
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v7i3.6083

Abstract

Plants Etlingera elatior (Wualae) is a family Zingiberaceae of ​​the genus Etlingera which has a large population in the world. The E. elatior plant is widely used empirically in the community to increase endurance and seasoning in fruit. In this study, ethanol extract was used to determine its potential and effectiveness as an antihyperuricemia (in vivo) was tested pharmacologically on Rattus novergicus L. In this study, twenty-four rats were grouped into six groups, namely the ethanol extract of wualae fruit at a dose (100 mg/kgBW, 200 mg/kgBW, 300 mg/kgBW, 400 mg/kgBW), and the negative control group Sodium CMC 0 .5%, and the positive control group used Allopurinol 10 mg/kgBW. Furthermore, To increase the value of uric acid levels, the rats were first induced with 250 mg/kgBW Potassium Oxonate via intraperitoneal (i.p). Furthermore, the preparation according to the treatment was given orally one hour later after the administration of potassium oxonate. At the hour (1, 2, 3), the blood was taken intravenously (i.v) through the rat's tail, and then the uric acid level was analyzed with a photometer. All doses used in this study, namely 100, 200, 300, and 400 mg/kgBW, showed that they could reduce uric acid overall. The effective dose used is the dose (300 mg/kgBW, 400 mg/kgBW). This research can be concluded that the ethanol extract of the fruit of Etlingera elatior (Jack) R.M. Smith (Wualae) has potential as an antihyperuricemia (uric acid) and can be developed as a traditional medicine
THE PREVALENCE AND DETERMINANTS OF DIARRHEA IN TODDLERS IN COASTAL AREA, NORTH BUTON REGENCY Irman Ado; Yusuf Sabilu; Muhammad Ilyas Yusuf; Swaidatul Masluhiyah A.F.; Erwin Erwin
Jurnal Farmasi Sains dan Praktis Vol 7 No 3 (2021): Supplementary Issue (The 4th National Pharmacy Conference 2021 Universitas Halu O
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v7i3.6161

Abstract

Diarrhea in children under five is still a disease with the second highest mortality rate after pneumonia. The World Health Organization (WHO) WHO recorded that around 5.6 million children under five died in 2016 and 8.8% were caused by diarrhea. The prevalence of diarrhea in Indonesia based on the results of Riskesdas (Basic Health Research) in 2018 decreased by 6.2 percent from Riskesdas in 2013 to 12.3%. Despite the decline, diarrhea remains the highest cause of under-five mortality among other diseases. This study is a quantitative descriptive study that aims to see the revalence and identify the determinants of diarrhea in children under five in coastal areas. The population and sample in this study were all data on diarrhea cases that occurred in the coastal area of ​​North Buton Regency during the observation period, from 2016 to 2020. The results showed that the prevalence of diarrhea in children under five in coastal areas was still quite high with a fluctuating pattern and Some of the determinant factors identified were environmental factors, namely clean water sources, family latrines, Waste Water Sewerage (WWS), heredity factors such as Low Birth Weight (LBW) and health service factors, namely Complete Basic Immunization (IDL). Further analysis is needed to determine the main determinants of the incidence of diarrhea in children under five in the coastal area in order to determine strategies for the prevention and control of diarrheal diseases in children under five.
Co-Authors Asriullah Jabbar Erwin Erwin Irman Ado Mesi Leorita Sahidin Sahidin Swaidatul Masluhiyah A.F. Wahyuni Wahyuni Yusuf Sabilu