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All Journal MNJ (Malang Neurology Journal) Callosum Neurology Journal : Jurnal Berkala Neurologi Bali Journal of Pain, Vertigo and Headache
Machlusil Husna
Departemen Neurologi, FK Universitas Brawijaya/RSUD Dr. Saiful Anwar, Malang, Jawa Timur, Indonesia
Health Professions Medicine & Pharmacology Neuroscience

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FENOMENA PSIKOSIS PADA PASIEN EPILEPSI: GAMBARAN KLINIS DAN TATALAKSANA Ria Damayanti; Machlusil Husna; Lovita Meika Savitri; Nur Izzati
Callosum Neurology Vol 4 No 1 (2021): Callosum Neurology Journal
Publisher : The Indonesia Neurological Association Branch of Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29342/cnj.v4i1.132

Abstract

Latar Belakang: Epilepsi terjadi akibat lepasnya muatan listrik yang berlebihan, paroksismal dan abnormal pada neuron otak. Kelainan di bidang psikiatri seringkali muncul bersama dengan epilepsi. Hampir 20% sampai 60% pasien epilepsi memiliki beberapa jenis komorbiditas psikiatri. Kelainan di bidang psikiatri yang paling umum pada pasien epilepsi adalah depresi, ansietas dan psikotik.  Tujuan: Pada artikel ini akan dibahas mengenai epilepsi dengan komorbiditas psikiatri terutama psikosis dari tinjauan klinis, patofisiologi dan manajemen yang direkomendasikan, sehingga dapat memperbaiki kualitas hidup pasien epilepsi secara umum. Diskusi: Secara umum psikosis epilepsi diklasifikasikan berdasarkan hubungannya dengan kejang yang yaitu iktal psikosis, postiktal psikosis dan interiktal psikosis. Epilepsi dengan komorbiditas psikiatri diduga disebabakan oleh faktor neuropatologi, neurokimia, genetik, dan psikososial. Simpulan: Pengetahuan khusus diperlukan untuk pemilihan obat anti epilepsi (OAE) pada pasien epilepsi dengan psikosis karena seringkali terjadi interaksi obat, efek sinergi, serta efek samping yang tidak diharapkan. Kata Kunci: Manajemen Psikosis, Epilepsi, Anti Psikotik, Anti Epilepsi
POST HERPETIC NEURALGIA AND OPHTAMOPLEGIA IN PATIENT WITH MULTIPLE SCLEROSIS : A CASE REPORT Widodo Mardi Santoso; Yeni Quinta Mondiani; Machlusil Husna; Rodhiyan Rachmatiar
Journal of Pain, Headache and Vertigo Vol. 1 No. 1 (2020): March
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (209.476 KB) | DOI: 10.21776/ub.jphv.2020.001.01.3

Abstract

Zoster Herpes which is also known as ‘shingles’ may cause infection on neuro system through the reactivation of the virus. This infection causes skin eruption along the affected dermatomal distribution and it is called post herpetics neuralgia. This condition occurs on approximately 9-15% patients of zoster herpes who receive no treatment. Elderly women have a higher risk of the condition. Complete oftamoplegia is also related with zoster herpes. It was reported that there were 16 cases in the past one year with a relatively good prognosis (total recovery within 18 months) with an analysis starting from inflammation of trigeminus nervus to cavernosus sinus, cranialis nervus microinfark caused by vasculitis, meningeal inflammation, and demyelinisation (of autopsy). On the other hand, there are theories showing a correlation between zoster herpes infection and multiple sclerosis. Based on the epidemiologic study which has been conducted, that zoster herpes is influencing multiple sclerosis. This virus might induce autoimmune cascade and proinflammatory via particle like Toll – like receptor 4 (TLR-4).
COMPARATIVE OF INTRAARTICULAR INJECTION BETWEEN DEXTROSE PROLOTHERAPY VERSUS TRIAMCINOLONE ACETONIDE IN KNEE OSTEOARTHRITIS Widodo Mardi Santoso; Andhy Indriyono; Badrul Munir; Alidha Nur Rakhmani; Machlusil Husna
Journal of Pain, Headache and Vertigo Vol. 1 No. 2 (2020): September
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (292.991 KB) | DOI: 10.21776/ub.jphv.2020.001.02.1

Abstract

Knee osteoarthritis (OA) is one of the most common cartilage degenerative disorders that is a major problem because it causes chronic pain and disability. Therefore the method of treatment and prevention of old age is a big challenge. The results of Dextrose Prolotherapy compared to Triamcinolone therapy research are still varied. Objective:  to  compare  the effectiveness  of  Dextrose  Prolotherapy  and  Triamcinolone Acetonide (TA) in the treatment of moderate knee knee OA.True experimental single blind study, at the Neurology Polyclinic Dr. Saiful Anwar General Hospital Malang for 6 months (July-December 2019). Group I; Dextrose Prolotherapy (15%) intraarticularly injected 3 times every 4 weeks and group II; TA one- time intraarticular injection. The parameters studied were The Western Ontario and McMaster  Universities  Osteoarthritis  Index  (WOMAC)  Score,  Numeric  Rating  Scale (NRS), and Range of Motion (ROM), weeks 0, 4, 8, 12 and 24. Forty samples consisted of; the 20 samples of the Dextrose Prolotherapy group consisted of; male: female = 2 (10%): 18 (90%), age 62.4 + 7.28, BMI 25.6 + 3.69 kg / m2, pain duration 22.35 + 20.10 months, history of physiotherapy 40.27 + 20.79 times. Kellgren–Lawrence osteoarthritis severity grade II; 17 (85%), grade III 3 (15%). TA group; male: female = 5 (25%):15 (75%), age 62.5 + 9.02, BMI 28.4 + 5.01 kg/m2, pain duration 15.95 +  16.55  months,  history  of  physiotherapy  34  +  24.87  times.  Kellgren  –  Lawrence osteoarthritis severity grade II; 18 (90%), grade III; 2 (10%). Comparison of NRS at rest Dextrose Prolotherapy vs TA of week 4 (2.60 vs 1.25), week 8 (1.65 vs 1.40), week 12 (0.8 vs 2.05), week 24 (0.75 vs 3.35). Comparison of NRS during activity Dextrose Prolotherapy vs TA week 4 (4.45 vs 3.35), week 8 (3.25 vs 3.55), week 12 (2.55 vs 4.30), week 24 (2.55 vs 5.80). Comparison of ROM flexion Dextrose Prolotherapy vs TA week 4 (127.05° vs 123.60°), week  8  (130.85°  vs  122.95°),  week  12  (130.85°  vs  122.95°),  week  24  (131.05°  vs 122.10°). Comparison of WOMAC score Dextrose Prolotherapy vs TA week 4 (30.05 vs 22.45), week 8 (22.90 vs 23.95), week 12 (19.30 vs 29.05), week 24 (18.95 vs 35.40). Intraarticular Injection Dextrose Prolotherapy is more effective for the long term based on pain scale NRS, WOMAC score and ROM. Whereas short-term TA is more effective than Dextrose Prolotherapy.
LOW BACK PAIN Andaru Cahya S; Widodo Mardi Santoso; Machlusil Husna; Badrul Munir; Shahdevi Nandar Kurniawan
Journal of Pain, Headache and Vertigo Vol. 2 No. 1 (2021): March
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (499.777 KB) | DOI: 10.21776/ub.jphv.2021.002.01.4

Abstract

Low back pain is the most common symptom found in the primary health care and is the number one cause of disability throughout worldwide. It is estimated that around 60 – 80% the world population will experience back pain during their lifespan. There are three different source of pain in the spine: axial-lumbosacral, radicular and reffered pain. All of these source brings different clinical presentations. Low back pain could be classified as acute, subacute and chronic low back pain. The pain could be nociceptive or neuropathic, the most common symptoms reported are “pressure pain” and “pain attack”.  The physician should be aware of “red flags” symptoms that lead into more serious condition beside back pain and, therefore the patient has to be investigated to further examination whenever these symptoms present. The management of low back pain consist of severe modalities, both therapeutic and rehabilitative procedure. Oftentimes, the management needed multidisciplinary approach. It is important to general practitioners to identify and treat low back pain appropriately to reduce the burden of the disease and to prevent the disabilties caused by this condition.
DEALING WITH UNCONTROLLED SEIZURE IN CATAMENIAL EPILEPSY: A CASE REPORT Machlusil Husna; I Wayan Arsana Wiyasa; Ria Damayanti; Syah Sembung Wasiso; Fahimma Fahimma; Kartika Agustina
MNJ (Malang Neurology Journal) Vol. 9 No. 1 (2023): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2023.009.01.16

Abstract

Catamenial epilepsy refers to a seizure pattern that coincides with the menstrual period. Patients with catamenial epilepsy often leads to intractable epilepsy and may have an adverse impact on quality of life. Several medications are the therapeutic options, however, there is uncertainty regarding the best treatment, and these medications often fail to control the seizure. This makes catamenial epilepsy categorized as pharmaco-resistant epilepsy. This paper reported a case of perimenstrual catamenial epilepsy with an uncontrolled seizure problem. Seizures still occur with optimal management, and thereby clinicians must continue to re-evaluate clinical conditions and treatment selection to achieve optimal management. Personalized-based treatment should be considered in catamenial epilepsy management. This report discusses the challenges of catamenial epilepsy, understanding the catamenial process, and dealing with the problem with a practical personalized approach.
POST HERPETIC NEURALGIA AND OPHTAMOPLEGIA IN PATIENT WITH MULTIPLE SCLEROSIS : A CASE REPORT Widodo Mardi Santoso; Yeni Quinta Mondiani; Machlusil Husna; Rodhiyan Rachmatiar
Journal of Pain, Headache and Vertigo Vol. 1 No. 1 (2020): March
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2020.001.01.3

Abstract

Zoster Herpes which is also known as ‘shingles’ may cause infection on neuro system through the reactivation of the virus. This infection causes skin eruption along the affected dermatomal distribution and it is called post herpetics neuralgia. This condition occurs on approximately 9-15% patients of zoster herpes who receive no treatment. Elderly women have a higher risk of the condition. Complete oftamoplegia is also related with zoster herpes. It was reported that there were 16 cases in the past one year with a relatively good prognosis (total recovery within 18 months) with an analysis starting from inflammation of trigeminus nervus to cavernosus sinus, cranialis nervus microinfark caused by vasculitis, meningeal inflammation, and demyelinisation (of autopsy). On the other hand, there are theories showing a correlation between zoster herpes infection and multiple sclerosis. Based on the epidemiologic study which has been conducted, that zoster herpes is influencing multiple sclerosis. This virus might induce autoimmune cascade and proinflammatory via particle like Toll – like receptor 4 (TLR-4).
COMPARATIVE OF INTRAARTICULAR INJECTION BETWEEN DEXTROSE PROLOTHERAPY VERSUS TRIAMCINOLONE ACETONIDE IN KNEE OSTEOARTHRITIS Widodo Mardi Santoso; Andhy Indriyono; Badrul Munir; Alidha Nur Rakhmani; Machlusil Husna
Journal of Pain, Headache and Vertigo Vol. 1 No. 2 (2020): September
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2020.001.02.1

Abstract

Knee osteoarthritis (OA) is one of the most common cartilage degenerative disorders that is a major problem because it causes chronic pain and disability. Therefore the method of treatment and prevention of old age is a big challenge. The results of Dextrose Prolotherapy compared to Triamcinolone therapy research are still varied. Objective:  to  compare  the effectiveness  of  Dextrose  Prolotherapy  and  Triamcinolone Acetonide (TA) in the treatment of moderate knee knee OA.True experimental single blind study, at the Neurology Polyclinic Dr. Saiful Anwar General Hospital Malang for 6 months (July-December 2019). Group I; Dextrose Prolotherapy (15%) intraarticularly injected 3 times every 4 weeks and group II; TA one- time intraarticular injection. The parameters studied were The Western Ontario and McMaster  Universities  Osteoarthritis  Index  (WOMAC)  Score,  Numeric  Rating  Scale (NRS), and Range of Motion (ROM), weeks 0, 4, 8, 12 and 24. Forty samples consisted of; the 20 samples of the Dextrose Prolotherapy group consisted of; male: female = 2 (10%): 18 (90%), age 62.4 + 7.28, BMI 25.6 + 3.69 kg / m2, pain duration 22.35 + 20.10 months, history of physiotherapy 40.27 + 20.79 times. Kellgren–Lawrence osteoarthritis severity grade II; 17 (85%), grade III 3 (15%). TA group; male: female = 5 (25%):15 (75%), age 62.5 + 9.02, BMI 28.4 + 5.01 kg/m2, pain duration 15.95 +  16.55  months,  history  of  physiotherapy  34  +  24.87  times.  Kellgren  –  Lawrence osteoarthritis severity grade II; 18 (90%), grade III; 2 (10%). Comparison of NRS at rest Dextrose Prolotherapy vs TA of week 4 (2.60 vs 1.25), week 8 (1.65 vs 1.40), week 12 (0.8 vs 2.05), week 24 (0.75 vs 3.35). Comparison of NRS during activity Dextrose Prolotherapy vs TA week 4 (4.45 vs 3.35), week 8 (3.25 vs 3.55), week 12 (2.55 vs 4.30), week 24 (2.55 vs 5.80). Comparison of ROM flexion Dextrose Prolotherapy vs TA week 4 (127.05° vs 123.60°), week  8  (130.85°  vs  122.95°),  week  12  (130.85°  vs  122.95°),  week  24  (131.05°  vs 122.10°). Comparison of WOMAC score Dextrose Prolotherapy vs TA week 4 (30.05 vs 22.45), week 8 (22.90 vs 23.95), week 12 (19.30 vs 29.05), week 24 (18.95 vs 35.40). Intraarticular Injection Dextrose Prolotherapy is more effective for the long term based on pain scale NRS, WOMAC score and ROM. Whereas short-term TA is more effective than Dextrose Prolotherapy.
LOW BACK PAIN Andaru Cahya S; Widodo Mardi Santoso; Machlusil Husna; Badrul Munir; Shahdevi Nandar Kurniawan
Journal of Pain, Headache and Vertigo Vol. 2 No. 1 (2021): March
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2021.002.01.4

Abstract

Low back pain is the most common symptom found in the primary health care and is the number one cause of disability throughout worldwide. It is estimated that around 60 – 80% the world population will experience back pain during their lifespan. There are three different source of pain in the spine: axial-lumbosacral, radicular and reffered pain. All of these source brings different clinical presentations. Low back pain could be classified as acute, subacute and chronic low back pain. The pain could be nociceptive or neuropathic, the most common symptoms reported are “pressure pain” and “pain attack”.  The physician should be aware of “red flags” symptoms that lead into more serious condition beside back pain and, therefore the patient has to be investigated to further examination whenever these symptoms present. The management of low back pain consist of severe modalities, both therapeutic and rehabilitative procedure. Oftentimes, the management needed multidisciplinary approach. It is important to general practitioners to identify and treat low back pain appropriately to reduce the burden of the disease and to prevent the disabilties caused by this condition.
Co-Authors Andaru Cahya S Andhy Indriyono Badrul Munir DAMAYANTI, ZUHRIA PUSPITA Fahimma Fahimma Kartika Agustina Lovita Meika Savitri Mondiani, Yeni Quinta Nur Izzati Rakhmani, Alidha Nur Rodhiyan Rachmatiar Shahdevi Nandar Kurniawan, Shahdevi Nandar Syah Sembung Wasiso Widodo Mardi Santoso Wiyasa, I Wayan Arsana