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Gambaran Radiologi untuk Deteksi Prenatal Osteogenesis Imperfecta -, Kartika; Suadiatmika, Dewa Gde Mahiswara
Cermin Dunia Kedokteran Vol 45, No 6 (2018): Penyakit Dalam
Publisher : PT. Kalbe Farma Tbk.

Osteogenesis imperfecta (OI) adalah kelainan heterogen genetik tulang dan jaringan ikat disebabkan mutasi dominan gen kolagen tipe I, COL1A1 dan COL1A2. Pemeriksaan radiologi masih menjadi alat skrining pertama untuk menentukan evaluasi genetik dini.Osteogenesis imperfecta (OI) is a genetic heterogenous disorder of bone and connective tissue caused by dominant mutation in collagen type I genes, COL1A1 and COL1A2. Radiological examination remains to be the first screening tool for early prenatal genetic evaluation.

KARAKTERISTIK GAMBARAN RADIOGRAFI POLOS DAN CT SCAN PADA KASUS CEDERA SERVIKAL DI RSUP SANGLAH BALI PERIODE JANUARI - DESEMBER 2018 Vennesia Stephany; Elysanti Dwi Martadiani; Firman Parulian Sitanggang; Dewa Gede Mahiswara Suadiatmika
E-Jurnal Medika Udayana Vol 10 No 7 (2021): Vol 10 No 07(2021): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2021.V10.i7.P16

ABSTRAK Cedera servikal adalah suatu keadaan darurat medis yang memerlukan perawatan yang sesegera dan setepat mungkin. Identifikasi cedera diperlukan sesegera mungkin untuk menghindari prognosis lebih buruk, salah satu caranya adalah dengan pemeriksaan penunjang radiologi. Penelitian ini bertujuan untuk mengetahui karakteristik cedera dan persentase gambaran radiografi yang dapat ditemui pada radiografi polos dan CT-Scan di RSUP Sanglah. Penelitian ini menggunakan metode deskriptif retrospektif melihat dari catatan rekam medis pasien cedera servikal dengan pemeriksaan penunjang radiografi polos atau CT Scan di RSUP Sanglah pada periode Januari – Desember 2018 dengan sampel sebanyak 34 pasien yang telah memenuhi kriteria inklusi dan eksklusi. Radiografi polos lebih banyak digunakan untuk pemeriksaan cedera servikal sebanyak 31 pasien (57,4%). Bagian anatomi dari servikal yang paling sering cedera adalah badan vertebra sejumlah 37 kasus (45,7%). Lokasi cedera terbanyak ada pada level C6 dan C5 pada radiografi polos (25,9%) dan CT Scan (29,4%), dan pada cedera multilevel paling banyak terdapat pada level C3-C4 pada radiografi polos (29,2%) dan CT Scan (28,6%). Pada radiografi polos ditemukan lebih banyak gambaran listesis sebanyak 13 kasus (31,8%) dan kompresi pada diskus sebanyak 20 kasus (48,8%), dan tidak ada temuan untuk gambaran stenosis dan pelebaran jarak atlantodental. Pada modalitas CT Scan lebih banyak ditemukan gambaran retropulsi sebanyak 5 kasus (12,5%), stenosis sebanyak 7 kasus (17,5%), dislokasi facet sebanyak 3 kasus (7,5%), dan pelebaran jarak atlantodental sebanyak 1 kasus (2,5%). Kata kunci : cedera servikal, radiografi polos, CT scan

Peripheral precocious puberty due to congenital adrenal hyperplasia with vanishing testis: a rare case in radiology Indira Prawita Martani; Pande Putu Yuli Anandasari; Dewa Gde Mahiswara Sudiatmika
Bali Anatomy Journal Vol 3 No 2 (2020): Bali Anatomy Journal (BAJ)
Publisher : Department of Anatomy, Medical Faculty, Universitas Udayana, Bali-Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36675/baj.v3i2.47

Background: Genetically, peripheral precocious puberty can be caused by congenital adrenal hyperplasia (CAH). Radiological examination is used for etiology findings and diagnostics. Peripheral precocious puberty of CAH generally affects girls with genitalia disambiguate, less common in boys. Incidence is I in 15.000 to 20.000 children with a female to male ratio of about 20:1. Case Report: A 5-year-old boy with voice change and hair growth in his penis. An immunoserology, endocrinology, electrolyte laboratory examination had been performed. Besides, some radiological tests of diagnostic bone age, upper abdominal ultrasound, and testicular ultrasound had been determined as confirmation of laboratory findings that support peripheral precocious puberty. In this case, an examination of human skeletal maturity was obtained according to the age of 14. Ultrasound examination showed adrenal enlargement with a size of 4 x 0.6 cm with a V-shaped and cribriform appearance. No testicular was found in the scrotum or the inguinal canal. Both 17-hydroxyprogesterone and testosterone level was increased subsequently. Conclusion: Bone age examination is needed to determine skeletal maturity. An ultrasound can be used to determine both etiology and concomitant abnormalities of the genital system. However, ultrasound can not detect the location of the testicle intraperitoneally. MRI examination is an imaging technique that is recommended if no testicles are found in the scrotum or inguinal.

Gambaran Radiologi untuk Deteksi Prenatal Osteogenesis Imperfecta Kartika -; Dewa Gde Mahiswara Suadiatmika
Cermin Dunia Kedokteran Vol 45, No 6 (2018): Penyakit Dalam
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v45i6.659

Osteogenesis imperfecta (OI) adalah kelainan heterogen genetik tulang dan jaringan ikat disebabkan mutasi dominan gen kolagen tipe I, COL1A1 dan COL1A2. Pemeriksaan radiologi masih menjadi alat skrining pertama untuk menentukan evaluasi genetik dini.Osteogenesis imperfecta (OI) is a genetic heterogenous disorder of bone and connective tissue caused by dominant mutation in collagen type I genes, COL1A1 and COL1A2. Radiological examination remains to be the first screening tool for early prenatal genetic evaluation.

Transarterial chemoembolization (TACE) in hepatocellular carcinoma BCLC B patients: case series Ni Nyoman Widyasari; Firman Parulian Sitanggang; Putu Patriawan; Dewa Gede Mahiswara
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Introduction: Hepatocellular carcinoma (HCC) is the fifth leading cause of death for men and the seventh for women worldwide, HCC is one out of 10 most cancers in Indonesia. HCC grows in the background of chronic liver disease and often associated with hepatitis virus infection such as hepatitis B virus (HBV) and hepatitis C virus (HCV). Transarterial chemoembolization (TACE) is a minimally invasive procedure performed by interventional radiologist as the treatment of choice for intermediate stage HCC.Case report: Here in we report a 62 and 59 years old female with hepatocellular carcinoma Barcelona clinic liver cancer (BCLC) B who were treated with TACE using 50 mg doxorubicin mixed with Iopamiro and lipiodol. Both were patients with history of HBV infection. After 5 weeks of TACE, triphase abdominal CT-Scan was done to evaluate tumour progression, however one patient was loss to follow up. Evaluation of one patient was done and revealed more than 30% decrease solid viable tumour with increase of necrotic area. Expansion of necrotic area is one of the HCC treatment response criteria, while decrease tumour enhancement explains the viability of the tumour itself.Conclusion: TACE is the therapy of choice for patient with HCC BCLC B, which can give enlargement of necrotic area and decrease tumour viability.

Pria 80 tahun dengan tumor ganas dinding dada: laporan kasus Raissa Andi Soekrisno; Dewa Gde Mahiswara Sudiatmika; Elysanti Dwi Martadiani; Firman Parulian Sitanggang; Herman Suputra
Intisari Sains Medis Vol. 12 No. 3 (2021): (Available online: 1 December 2021)
Publisher : DiscoverSys Inc.

Background: Malignant tumors that form in bone, soft tissue, or cartilage, are called sarcomas. Symptoms of these tumors vary, and may include shortness of breath, chest pain, and swelling around the tumor. Imaging such as X-rays and CT scans can be helpful, although imaging features of the few malignant chest wall tumors that are less specific, knowledge of the typical radiographic manifestations of these tumors can often make it easier for experts to differentiate between benign and malignant tumors and help lead to a more specific diagnosis.Case presentation: An 80-year-old man complains of a lump in the right chest. The results of laboratory tests showed anemia, decreased kidney function, and hypercalcemia. The CT scan of the thorax with contrast showed a solid mass in the right pleural cavity infiltrating the surrounding chest wall muscles, bilateral pneumonia, and osteolytic lesions on the spine suspected of being a metastatic process or spreading malignancy. The results of the biopsy showed a diffuse morphological appearance of immature plasma cells with an approach to the diagnosis of cutaneous infiltration plasma cell myeloma with a differential diagnosis of plasmablastic lymphoma.Conclusion: The results of X-ray imaging and CT scan of the thorax help narrow the differential diagnosis, where there is an image of a tumor on the chest wall with destruction of the surrounding bone and soft tissue and an image of infiltration into the pleura accompanied by multiple osteolytic images of the vertebrae. Assisted by a biopsy (anatomical pathology), the closest diagnosis in this patient is plasma cell myeloma chest wall. Latar Belakang: Tumor ganas yang terbentuk pada tulang, jaringan lunak, atau kartilago disebut sarcoma. Gejala dari tumor ini bervariasi, dapat berupa sesak nafas, nyeri dada, dan pembengkakan pada sekitar tumor. Pencitraan seperti rontgen dan CT scan dapat membantu, walaupun gambaran pencitraan dari beberapa tumor ganas dinding dada kurang spesifik, pengetahuan tentang manifestasi tipikal pada radilogi dari berbagai tumor ini seringkali dapat memudahkan para ahli untuk membedakan jenis tumor jinak dan ganas dan membantu mengarahkan diagnosis yang lebih spesifik.Kasus: Seorang laki – laki berusia 80 tahun dengan keluhan benjolan di dada sebelah kanan. Hasil pemeriksaan laboratorium didapatkan hasil anemia, penurunan fungsi ginjal, dan hiperkalsemia. Hasil CT Scan thorax dengan kontras menunjukkan adanya massa solid pada cavum pleura kanan yang menginfiltrasi otot dinding dada di sekitarnya, pneumonia bilateral, serta lesi osteolitik pada tulang belakang yang dicurigai sebagai suatu proses metastase atau penyebaran keganasan. Hasil biopsi menunjukkan gambaran morfologi sebaran difus sel plasma imatur-matur dengan pendekatan pada diagnosis cutaneus infiltration plasma cell myeloma dengan diagnosis banding plasmablastic lymphoma.Simpulan: Hasil pencitraan rontgen dan CT scan thorax membantu menyempitkan diagnosis banding, di mana terdapat gambaran tumor pada dinding dada dengan destruksi tulang dan jaringan lunak di sekitarnya serta gambaran infiltrasi ke pleura disertai gambaran osteolitik multipel pada vertebrae. Dibantu dengan pemeriksaan biopsi (patologi anatomi) maka diagnosis yang paling mendekati pada pasien ini adalah plasma cell myeloma dinding dada

Karakteristik gambaran Tuberkulosis (TB) paru pada foto toraks pasien Human Immunodeficiency Virus (HIV) tahun 2017-2021 di RSUP Sanglah, Bali, Indonesia Tiffany Rebecca; Dewa Gde Mahiswara Suadiatmika; Ni Nyoman Margiani
Intisari Sains Medis Vol. 12 No. 3 (2021): (Available online: 1 December 2021)
Publisher : DiscoverSys Inc.

Background: Tuberculosis is a disease caused by Mycobacterium tuberculosis that mostly attacks the lungs. HIV is a virus that causes damage to the immune system. HIV infection increases the risk of developing pulmonary TB because TB is an opportunistic disease; vice versa TB infection increases HIV progression. This study is about researching the characteristics of TB in HIV patients radiologically at Sanglah Hospital Denpasar.Methods: This study is a cross-sectional descriptive study conducted retrospectively. The data in this study used medical records of HIV-infected pulmonary TB patients from Sanglah Hospital, especially the characteristics of chest radiographs in the medical records and chest X-rays of patients. For the data collecting technique, a total sample is used to analyze all 47 cases. Data were analyzed using SPSS version 25 for Windows.Results: Most HIV patients with pulmonary TB coinfection at Sanglah Hospital, Denpasar, were obtained from as many as 47 people. It was found that the age between 30 - 39 recorded to be the highest at 31.3%, men were the most dominant with 81.3%, most of the patients diagnosed with HIV stage 4 were 72.9%, and the most dominant characteristics of the chest radiograph are 41.7% consolidation.Conclusion: Most cases of pulmonary TB with HIV coinfection at Sanglah Hospital Denpasar in 2017 - 2021 are male around 30 - 39 years. In addition, most of them were diagnosed with HIV stage 4 and finally almost all the patients had consolidation characteristics on chest radiographs. Latar Belakang: Tuberkulosis adalah penyakit yang disebabkan oleh Mycobacterium tuberculosis yang paling banyak menyerang paru-paru. HIV adalah virus yang menyebabkan kerusakan pada sistem kekebalan tubuh. Infeksi HIV meningkatkan risiko berkembangnya TB paru karena TB adalah penyakit oportunistik sebaliknya infeksi TB meningkatkan perkembangan HIV. Penelitian ini bertujuan untuk mengetahui karakteristik TB pada pasien HIV secara radiologis di RSUP Sanglah Denpasar.Metode: Penelitian ini merupakan penelitian deskriptif potong lintang yang dilakukan secara retrospektif. Data dalam penelitian ini menggunakan rekam medis pasien TB paru terinfeksi HIV dari RSUP Sanglah, terutama karakteristik foto toraks pada rekam medis dan foto rontgen dada pasien. Untuk teknik pengumpulan data, sampel total digunakan untuk menganalisis semua 47 kasus. Data dianalisis dengan SPSS versi 25 untuk Windows.Hasil: Pasien HIV koinfeksi TB paru terbanyak di RS Sanglah Denpasar didapatkan sebanyak 47 orang. Didapatkan usia antara 30-39 tahun tercatat paling tinggi 31,3%, laki-laki paling dominan dengan 81,3%, sebagian besar pasien terdiagnosis HIV stadium 4 sebanyak 72,9%, dan karakteristik foto toraks yang paling dominan adalah konsolidasi 41,7%.Kesimpulan: Kasus TB paru koinfeksi HIV terbanyak di RSUP Sanglah Denpasar tahun 2017 – 2021 adalah laki-laki berusia sekitar 30–39 tahun. Selain itu, sebagian besar terdiagnosis HIV stadium 4 serta hampir semua pasien memiliki karakteristik konsolidasi pada radiografi dada.

A Case Report: Serial Case of Spontaneous Pneumomediastinum and Subcutaneous Emphysema in COVID-19 Patients Anggreini, Faradilla Novita; Dewi, Putu Utami; Sitanggang, Firman Parulian; Suadiatmika, Dewa Gde Mahiswara
Indonesian Journal of Global Health Research Vol 7 No 2 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i2.5924

Coronaviruses are pathogens that affect both humans and animals and play a significant role in one of the most persistent disease outbreaks to date, known as Coronavirus Infectious Disease 2019 (COVID-19). The COVID-19 pandemic, declared by the World Health Organization (WHO) in March 2020, was classified as a global public health emergency due to its continued transmission, widespread impact, and the emergence of various viral variants. Before the development of vaccines, at the early stage of the pandemic, there were 5,596,550 confirmed COVID-19 cases worldwide, with a mortality rate of 353,373 cases. This study present Serial Case of Spontaneous Pneumomediastinum and Subcutaneous Emphysema in COVID-19 Patients. This study was a case report that describing detailed account of a patient's diagnosis, treatment, and follow-up a rare case. A critical review of the case report was conducted to assess the validity and reliability of the findings and to identify any limitations of the study. We present a serail case of Spontaneous Pneumomediastinum and Subcutaneous Emphysema in COVID-19. Various case reports and studies have shown that subcutaneous emphysema and pneumomediastinum can occur in COVID-19 patients both with and without mechanical ventilation (spontaneously). Extensive subcutaneous emphysema causing airway compression is an extremely rare manifestation of COVID-19 infection. Subcutaneous emphysema and pneumomediastinum are uncommon conditions associated with COVID-19 and can indicate a poor prognosis, leading to increased morbidity and prolonged hospitalization. Pneumomediastinum, pneumothorax, and subcutaneous emphysema may arise as complications of COVID-19 itself or as consequences of its management, such as mechanical ventilation or other iatrogenic interventions.

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