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All Journal Jurnal Kesehatan Bina Generasi Prosiding University Research Colloquium
Arum Kartikadewi
Universitas Muhammadiyah Semarang
Humanities Computer Science & IT Dentistry Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health

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Efek Perlakuan Kombinatif Plasma Medis dan Ekstrak Daun Binahong Terhadap Penyembuhan Luka Fase Proliferasi Pada Mencit Diabetik Eka Sakti Wahyuningtyas; N Nasruddin; Heni Setyowati Esti Rahayu; Heni Lutfiyati; Isabella Meliawati Sikumbang; Laela Hayu Nurani; Arum Kartikadewi; Nia Salsabila; Gela Setya Ayu Putri; Putri Kurniasiwi; Devi Kemala Dewi
Prosiding University Research Colloquium Proceeding of The 12th University Research Colloquium 2020: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Plasma medicine is a relatively new and multidisciplinary studyinvolving the study of plasma science, biomedicine, pharmacy, andother health sciences to utilizing plasma for medical therapy. Plasmais the fourth substance, after solids, liquids, and gases. Plasma canproduce biological molecules of Reactive Oxygen and NitrogenSpecies (RON) which, if controlled in the right dose, can bebeneficial for health. This animal study examines the effect ofcombinative treatment of medicine plasma and binahong leaf extracton proliferation phase wound healing in a diabetic test model. Thestudy used Balb mice 7-8 years old which were induced by STZ withacute wounds which were divided into 4 groups, namely the woundgroup of diabetic mice without treatment (C), the group of diabeticmice with the treatment of binahong leaf extract (B), the group ofcombined treatment wounds plasma jet (P) and the wound group ofdiabetic mice treated with a combination of plasma and, binahongleaf extract (PB). Binahong leaf extract concentration 1% in DMSOsolvent. The jet type medicine plasma treatment was carried outevery day from day 0 to day 6. Macroscopic observation of thewound was carried out every day from day 0 to day 7. On day 7 itappears that the size of the wound area for P is much smaller thanfor C, B, and PB. The size of area B and PB is relatively the same,but smaller than C. The results of this study indicate that thebinahong leaf extract tends to inhibit the performance of medicineplasma in accelerating the healing of the proliferation phase.
KORELASI HbA1c DAN GULA DARAH PUASA TERHADAP RASIO TG/HDL-K PASIEN DIABETES MELLITUS TIPE 2 BERETNIS JAWA Yanuarita Tursinawati; Sakinah; Zulfachmi Wahab; Arum Kartikadewi
Bina Generasi : Jurnal Kesehatan Vol 15 No 1 (2023): Bina Generasi : Jurnal Kesehatan
Publisher : LPPM STIKES BINA GENERASI POLEWALI MANDAR

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35907/bgjk.v15i1.259

Abstract

Background : Most of the causes of death in type 2 Diabetes Mellitus (T2DM) are coronary heart disease (CHD) with dyslipidemia as one of its risk factors. The best marker for early detection of dyslipidemia is the ratio of triglycerides to high-density lipoprotein cholesterol (TG/HDL-C). In T2DM patients, glycemic control in the form of Fasting Blood Sugar (GDP) and HbA1c can be done to avoid the risk of CHD. This study aims to identify the correlation of Hba1c and GDP with the ratio of TG/HDL-K in T2DM patients with Javanese ethnicity.Methods : This research was a cross sectional study involving 107 respondents from several health centers in Semarang City with consecutive sampling method. GDP, HbA1c, and TG/HDL-K ratio were obtained from medical records. Spearman correlation statistical test was used with a significance value of p <0.05. Results: The average HbA1c (7.86 ±1.97%), GDP (160.36± 76.82gr/dL), and the TG/HDL-K ratio (3.50± 2.22) exceeded the normal number. There was a weak significant correlation between GDP and the TG/HDL-K ratio (p=0.020; r=0.224) and there was no correlation between HbA1c and the TG/HDL-K ratio (p=0.549; r=0.059) in T2DM patients with Javanese ethnicity.Conclusion: The GDP of Javanese T2DM patients is weakly correlated with the TG/HDL-K ratio but not with HbA1c. Glycemic control is needed as an early marker of CHD risk in T2DM.
Co-Authors Devi Kemala Dewi Eka Sakti Wahyuningtyas Gela Setya Ayu Putri Heni Lutfiyati Heni Setyowati Esti Rahayu Isabella Meliawati Sikumbang Laela Hayu Nurani N Nasruddin Nia Salsabila Putri Kurniasiwi Sakinah Wahab, Zulfachmi Yanuarita Tursinawati