Article Per Year (5 Year)
p-Index From 2021 - 2026
0.983
P-Index
This Author published in this journals
All Journal Jurnal Kesehatan Andalas Jurnal Kedokteran dan Kesehatan JURNAL IBNU SINA BIOMEDIKA Jurnal Kesehatan Bina Generasi KOLONI Essentia: Journal of Medical Practice and Research
Wahab, Zulfachmi
FK Universitas Muhammadiyah Semarang
Civil Engineering, Building, Construction & Architecture Dentistry Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

Published : 6 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 6 Documents
Search

 1 
PERUBAHAN KADAR HEMOGLOBIN DAN NILAI ENZIM AMINOTRANSFERASE PADA TERAPI ANTIRETROVIRAL LINI PERTAMA Ratnaningrum, Kanti; Wahab, Zulfachmi; Augatha, Arrafli Bagas
JURNAL IBNU SINA BIOMEDIKA Vol 2, No 1 (2018)
Publisher : UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (553.6 KB) | DOI: 10.30596/isb.v2i1.1832

Abstract

Pendahuluan: Terapi Anti Retroviral (ARV) lini pertama (Human Immunodeficiency Virus) HIV masih digunakan sebagai pilihan utama dalam pengobatan HIV. Penggunaan ARV memerlukan pemantauan nilai laboratorium untuk meghindari efek samping akibat terapi tersebut. Sedikitnya informasi tentang efek samping terapi ARV dan semakin banyaknya kasus pasien HIV menyebabkan peneliti ingin mengetahui jumlah penurunan kadar hemoglobin dan peningkatan nilai enzim amino transferase pada pasien HIV dengan terapi ARV lini pertama kombinasi duviral dan neviral.Metode: Penelitian ini merupakan studi observasional analitik dengan pendekatan cross  sectional, dengan metode consecutive  sampling. Data merupakan data sekunder pasien HIV di RSUD Ambarawa. Kriteria inklusi berusia ≥18 tahun, menjalani 1 tahun pengobatan dalam kurun waktu 2011-2015 dengan kombinasi duviral dan neviral. Data dianalisis menggunakan uji T berpasangan untuk kadar hemoglobin dan uji chi square untuk nilai enzim aminotransferase.Hasil: Dari 37 sampel, terdapat sigifikansi antara terapi anti retroviral lini pertama terhadap perubahan kadar hemoglobin (p=<0,001) dengan delta penururan 3,29 mg/dl dan nilai enzim aminotransferase yaitu nilai SGPT (p=<0,001) dengan delta peningkatan 14,09 IU serta SGOT (p=0,021) dengan delta peningkatan 11,40 IU.Simpulan: Terjadi penurunan kadar hemoglobin sebesar 3,29 mg/dl, peningkatan nilai enzim aminotransferase sebesar 14,09 IU pada SGPT serta 11,40 IU pada SGOT setelah terapi ARV lini pertama.
Ankle Brachial Index pada Penderita Diabetes dan Non Diabetes, dan Hubungannya dengan Aktivitas Fisik dan Perilaku Merokok Arum Kartikadewi; Setyoko Setyoko; Zulfachmi Wahab; Kharisma Andikaputri
Jurnal Kedokteran dan Kesehatan Vol 18, No 1 (2022): JURNAL KEDOKTERAN DAN KESEHATAN
Publisher : Faculty of Public Health, Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/jkk.18.1.57-68

Abstract

Ankle Brachial Index (ABI) adalah prediktor utama untuk menilai adanya penyakit arteri perifer pada penderita Diabetes Melitus (DM) dan non DM. Terdapat perbedaan faktor risiko terhadap abnormalitas ABI antara penderita DM dan non DM. Penelitian bertujuan mengetahui perbedaan faktor yang mempengaruhi ABI pada penderita DM dan non DM etnis Jawa.Desain penelitian adalah observasional analitik dengan pendekatan case control. Sampling dilakukan dengan cara consecutive sampling. Perbedaan faktor yang mempengaruhi ABI dianalisis dengan  uji Chi-square. Faktor yang signifikan mempengaruhi ABI pada responden DM adalah usia (p-value=0,04) dan aktivitas fisik (p-value=0,02) dan faktor yang tidak signifikan adalah jenis kelamin (p-value=1,00), lama DM (p-value=0,31), tekanan darah (p-value=0,75), dan status merokok (p-value=1,00). Sedangkan, faktor yang signifikan mempengaruhi ABI pada responden non DM adalah aktivitas fisik (p-value=0,01) dan faktor yang tidak signifikan adalah jenis kelamin (p-value=0,31), usia (p-value=0,08), tekanan darah (p-value=0,93), dan status merokok (p-value=0,32). Faktor yang mempengaruhi ABI pada responden DM adalah usia dan aktivitas fisik, sedangkan pada responden non DM adalah aktivitas fisik.
Hubungan antara Kadar HbA1c dan Derajat Retinopati Pasien Diabetes Melitus Tipe 2 di Rumah Sakit Mata Cicendo Bandung Fathia Farhani; Zulfachmi Wahab; Yanuarita Tursinawati
Jurnal Kesehatan Andalas Vol 12, No 1 (2023): Online March 2023
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v12i1.2157

Abstract

Diabetic retinopathy is the common complication of T2DM, which leads to vision loss. The severity of retinopathy can be affected by HbA1c levels. Controlling the glycemic such as HbA1c, may prevent the severity of diabetic retinopathy. Objective: To identified the association between HbA1c levels and severity of retinopathy in Type 2 DM patients at Cicendo Eye Hospital, Bandung. Methods: This research was an analytic observational study and cross-sectional approach. Samples were taken using purposive sampling and consisted of 70 people. The secondary data were from the outpatient's medical records at the Cicendo Eye Hospital in Bandung for the period September-October 2022. The Chi-square test was used for data analysis. Results: According to HbA1c levels, the uncontrolled HbA1C levels were found in 52 patients (74,3%) and the controlled were found in 18 patients (25,7%). Most of them were diagnosed with PDR were found 62% and the rest of it were diagnosed with NPDR. A significant association is found between HbA1c levels and the degree of diabetic retinopathy with p-value = 0.018 (p <0.05). Conclusion: HbA1c levels in Type 2 Diabetes Mellitus patients have a significant association with the severity of diabetic retinopathy, which can be used as a parameter for controlling diabetes complications, particularly retinopathy.Keywords: diabetic retinopathy, T2DM, HbA1c, glycemic control
KORELASI HbA1c DAN GULA DARAH PUASA TERHADAP RASIO TG/HDL-K PASIEN DIABETES MELLITUS TIPE 2 BERETNIS JAWA Yanuarita Tursinawati; Sakinah; Zulfachmi Wahab; Arum Kartikadewi
Bina Generasi : Jurnal Kesehatan Vol 15 No 1 (2023): Bina Generasi : Jurnal Kesehatan
Publisher : LPPM STIKES BINA GENERASI POLEWALI MANDAR

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35907/bgjk.v15i1.259

Abstract

Background : Most of the causes of death in type 2 Diabetes Mellitus (T2DM) are coronary heart disease (CHD) with dyslipidemia as one of its risk factors. The best marker for early detection of dyslipidemia is the ratio of triglycerides to high-density lipoprotein cholesterol (TG/HDL-C). In T2DM patients, glycemic control in the form of Fasting Blood Sugar (GDP) and HbA1c can be done to avoid the risk of CHD. This study aims to identify the correlation of Hba1c and GDP with the ratio of TG/HDL-K in T2DM patients with Javanese ethnicity.Methods : This research was a cross sectional study involving 107 respondents from several health centers in Semarang City with consecutive sampling method. GDP, HbA1c, and TG/HDL-K ratio were obtained from medical records. Spearman correlation statistical test was used with a significance value of p <0.05. Results: The average HbA1c (7.86 ±1.97%), GDP (160.36± 76.82gr/dL), and the TG/HDL-K ratio (3.50± 2.22) exceeded the normal number. There was a weak significant correlation between GDP and the TG/HDL-K ratio (p=0.020; r=0.224) and there was no correlation between HbA1c and the TG/HDL-K ratio (p=0.549; r=0.059) in T2DM patients with Javanese ethnicity.Conclusion: The GDP of Javanese T2DM patients is weakly correlated with the TG/HDL-K ratio but not with HbA1c. Glycemic control is needed as an early marker of CHD risk in T2DM.
Cardiovascular Disease Risk Score Correlates with Glomerular Filtration Rate in Hemodialysis Patients: A Cross-Sectional Pilot Study Nabil Hajar; Bintang Adhiyoso Wicaksono; Zulfachmi Wahab; Shofa Chasani; Galih Prakasa Adhyatma; Nabila Nuralya Joveazhari; Zeidan Ahmad Fahdalhaq
Journal of Medical Practice and Research Vol 2 No 1 (2026): June: Essentia: Journal of Medical Practice and Research
Publisher : CV SCRIPTA INTELEKTUAL MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65310/2v7hr182

Abstract

Chronic kidney disease is closely linked to an elevated risk of cardiovascular morbidity and mortality, particularly among patients undergoing hemodialysis. This study aimed to examine the relationship between cardiovascular disease risk scores and renal function using an empirical cross-sectional design. A total of 72 eligible patients receiving hemodialysis were assessed using the World Health Organization Risk Prediction Chart for Southeast Asia Region B to estimate 10-year cardiovascular risk. Renal function was evaluated using the Cockcroft–Gault equation to determine glomerular filtration rate values. Descriptive analysis demonstrated a predominance of high cardiovascular risk categories alongside severely reduced renal function. Inferential analysis using the Spearman rank correlation test revealed a statistically significant inverse relationship between cardiovascular risk score and glomerular filtration rate (r = -0.637; p = 0.000). These findings indicate that higher cardiovascular risk is associated with more severe renal impairment. The results support the integration of cardiovascular risk assessment into routine clinical evaluation of patients with chronic kidney disease undergoing hemodialysis to improve early risk stratification and management strategies.  
Perbandingan Efektivitas Kombinasi OHO (Obat Hipoglikemik Oral) Terhadap Gula Darah Puasa Pasien Diabetes Melitus Tipe 2 Comparison of the Effectiveness of Oral Hypoglycemic Agents (OHO) on Fasting Blood Glucose Levels in Type 2 Diabetes Mellitus Patients Talitha Elliora Salsabilla; Zulfachmi Wahab; Yanuarita Tursinawati
KOLONI Vol. 5 No. 2 (2026): JUNI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v5i2.966

Abstract

Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disease characterized by insulin resistance and impaired insulin secretion, leading to increased blood glucose levels. Optimal blood glucose control is necessary to prevent long-term complications. One of the parameters used to assess glycemic control is Fasting Blood Glucose (FBS). This study aims to compare the effectiveness of the combination of metformin-glimepiride and metformin-gliclazide on FBS levels in T2DM patients. This study is a quantitative, observational, and analytical study using a cross-sectional approach. Data were obtained from the medical records of outpatients with T2DM at K.R.M.T. Wongsonegoro Regional General Hospital from January 2022 to December 2023. The study sample consisted of 50 patients selected using a purposive sampling technique, consisting of 25 patients receiving metformin-glimepiride therapy and 25 patients receiving metformin-gliclazide therapy. Data analysis was performed using the Paired T-Test, Mann–Whitney, and Independent T-Test. The results showed that both therapy combinations resulted in significant reductions in GDP after three months of therapy. The Mann–Whitney test showed no significant difference in GDP reduction between the two groups. However, the Independent T-Test showed a significant difference in final GDP levels, with the metformin-gliclazide group having a lower mean final GDP than the metformin-glimepiride group. Therefore, the metformin-gliclazide combination is superior in controlling GDP levels in patients with type 2 diabetes compared to the metformin-glimepiride combination.
Co-Authors Arum Kartikadewi Arum Kartikadewi Augatha, Arrafli Bagas Bintang Adhiyoso Wicaksono Fathia Farhani Galih Prakasa Adhyatma Kanti Ratnaningrum Kharisma Andikaputri Nabil Hajar Nabila Nuralya Joveazhari Sakinah Setyoko Setyoko Shofa Chasani Talitha Elliora Salsabilla Yanuarita Tursinawati Yanuarita Tursinawati Zeidan Ahmad Fahdalhaq