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All Journal JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Insan Farmasi Indonesia Jurnal Bakti Untuk Negeri
Hayatus Sa’adah
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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PENYULUHAN PENCEGAHAN HIPERTENSI DENGAN CERDIK Octariana Sofyan; Andi Wijaya; Fara Azzahra; Mexsi Mutia Rissa; Hayatus Sa’adah; Danang Yulianto
Jurnal Bakti untuk Negeri Vol 2 No 2 (2022): JBN
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Hypertension is a condition where the pressure exceeds the normal limit. Uncontrolled high blood pressure can be a risk factor for cardiovascular disease. High blood pressure is still a dominant health problem and requires a good treatment. Counseling to the community of Ledok Timoho village, Muja Muju Umbulharjo Village, Yogyakarta on how to prevent and control hypertension and improve it. The method of activity used in this community service is in the form of counseling on the prevention and control of hypertension, followed by a question and answer discussion, and evaluation of activities using a questionnaire. The results of the implementation of community service showed that there was an increase in the knowledge of PKK mothers about the prevention and control of hypertension in the community from 86.30% to 100%
FORMULASI SEDIAAN TABLET HISAP DARI EKSTRAK ETANOL BUAH KARAMUNTING (Melastoma polyanthum) SEBAGAI ANTIOKSIDAN Nor Latifah; Hayatus Sa’adah; Retna Eka Dewi
JCPS (Journal of Current Pharmaceutical Sciences) Vol 7 No 1 (2023): September 2023
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Buah karamunting (Melastoma polyanthum) termasuk tanaman khas Kalimantan Selatan yang dilaporkanmengandung antioksidan yang sangat kuat. Karamunting mengandung senyawa golongan antrakinon, fenolik, terpenoid dan flavonoid, selain itu juga mengandung unsur kalium dan natrium. Metode yang digunakan yaitu ekstrak buah karamunting diperoleh dengan cara maserasi menggunakan pelarut etanol 96% serta metode freeze dry untuk menghasilkan ekstrak kering buah karamunting. Tablet hisap menggunakan metode granulasi basah dengan membuat beberapa seri konsentrasi PVP sebagai pengikat dengan variasi F1 (6%), F2 (8%), dan F3 (10%).Berdasarkan hasil evaluasi granul semua formula memenuhi persyaratan yang ditentukan. Selain itu untuk hasilevaluasi tablet hisap dari ketiga formula tersebut terdapat pada F2 dan F3 yang memenuhi semua persyaratan tablet hisap. Sedangkan nilai IC50 yang diperoleh pada ekstrak freeze dry buah karamunting yaitu 18,5787 ppm, selain itu hasil uji aktivitas antioksidan tablet hisap buah karamunting menunjukkan bahwa F1, F2, dan F3 mempunyai nilai IC50sebesar 85,221; 69,234; dan 85,082 ppm. Dari hasil penelitian Formulasi Sediaan Tablet Hisap Dari Ekstrak Freeze dry Buah Karamunting (Melastoma polyanthum) sebagai Antioksidan, disimpulkan bahwa sediaan tablet hisap telah memenuhi persyaratan uji sifat fisik yang terdapat pada formula 2 dan formula 3 serta menghasilkan sediaan tablet hisap yang memiliki aktivitas antioksidan dengan kategori kuat.
PENGARUH KOMBINASI PELARUT EKSTRAKSI ETANOL 96%-ETIL ASETAT (1:1) DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb.) TERHADAP PERTUMBUHAN BAKTERI Bacillus subtilis Hasani, Najwi; Muhammad Awaluddin Padjrin; Daipadli; Hayatus Sa’adah
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2306

Abstract

The leaves of Pandan Wangi (Pandanus amaryllifolius Roxb.) are known for their antibacterial properties, containing bioactive compounds such as alkaloids, flavonoids, saponins, tannins, polyphenols, essential oils, steroids, and terpenoids. This study aimed to evaluate the antibacterial activity of ethanol-ethyl acetate (1:1) extract of Pandan Wangi leaves against Bacillus subtilis using the well diffusion method. The extract was prepared through maceration, and phytochemical screening confirmed the presence of alkaloids, flavonoids, saponins, phenols, and steroids. Antibacterial activity was assessed at concentrations of 1%, 5%, 10%, 20%, 30%, 40%, and 50%. The results indicated that the extract exhibited significant antibacterial activity at concentrations of 10% and above, producing inhibition zones of 8.39 mm, 10.33 mm, 11.27 mm, 13.37 mm, and 15.57 mm for 10%, 20%, 30%, 40%, and 50% respectively. No inhibition was observed at 1% and 5% concentrations. In conclusion, the ethanol-ethyl acetate extract (1:1) of Pandan Wangi leaves demonstrated effective antibacterial activity against B. subtilis at a minimum concentration of 10%, confirming its potential as a natural antibacterial agent.
Co-Authors Andi Wijaya Daipadli Daipadli Danang Yulianto Dewi, Retna Eka Fara Azzahra M. Awaluddin Padjrin Mexsi Mutia Rissa Nor Latifah Octariana Sofyan