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All Journal JFL : Jurnal Farmasi Lampung Jurnal Media Pengabdian Kepada Masyarakat (JM-PKM)
Yuli Wahyu Tri Mulyani
Program Studi Farmasi Universitas Tulang Bawang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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AKTIVITAS ANTIPIRETIK KOMBINASI EKSTRAK ETANOLMENIRAN (Phyllanthus niruriL) DAN DAUN BELIMBING WULUH (Avverhoabillimbi) PADA TIKUS PUTIH JANTAN YANG DIINDUKSI VAKSIN DPT-Hb Yuli Wahyu Tri Mulyani; Annisa Mulia Anasis; Vatiyah Hari Utami
JFL : Jurnal Farmasi Lampung Vol. 11 No. 1 (2022): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v11i1.705

Abstract

Abstract Fever is defined as a change in the body's temperature regulation mechanism which results in an increase in body temperature above normal above 32.7ºC. Antipyretics are drugs used to reduce fever, one of which is paracetamol, but the use of paracetamol in large doses and for a long time has the potential to cause damage to the kidneys, brain, liver (hepatotoxic), disorders of the digestive system, respiratory system and hematological effects. These unwanted effects can be minimized using the active ingredients of meniran (Phylantus niruri L) and wuluh (Avverhoa bilimbi) plants. The purpose of this study was to prove the antipyretic activity of the combination of meniran leaf extract (Phylantus niruri L) and wuluh starfruit leaf (Avverhoa bilimbi) in male white rats (Rattus norvegicus L) induced by the DPT-Hb vaccine. The principle of this research is laboratory experimental research. This study included a combination of samples of meniran leaves and starfruit leaves, making thick extracts of meniran leaves and starfruit leaves, and testing the effect of antipyretics on the test animals. This study used the DPT–Hb (fever) vaccine induction method and the SPSS analysis method. The results showed that ethanol extract of meniran leaves 200mg/200grBB, ethanol extract of belimbing wuluh leaves 7.2mg/200grBB and a combination of ethanolic extract of meniran leaves with starfruit at doses of 200mg/200grBB and 7.2mg/200grBB, 100mg/200grBB and 3.6mg/ 200grBW, 200mg/200grBW and 3.6mg/200grBW, 100mg/200grBW, and 7.2mg/200grBW had antipyretic effects on male white rats. Keywords: antipyretic, starfruit, meniran
UJI DAYA HAMBAT ANTIBAKTERI KOMBINASI EKSTRAK DAUN PEPAYA ( Carica papaya L. ) DENGAN DAUN SIRIH ( Piper betle L. ) TERHADAP BAKTERI Staphylococcus aureus Amy Siska Zulyani; Samsuar Samsuar; Yuli Wahyu Tri Mulyani; Muti Dianda Sari
JFL : Jurnal Farmasi Lampung Vol. 11 No. 1 (2022): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v11i1.714

Abstract

Infection is a disease that is often found in Indonesia. Infectious diseases can be caused by one of the gram-positive bacteria, staphylococcus aureus bacteria. How to prevent infectious diseases is to inhibit the growth of Staphylococcus aureus bacteria. Papaya leaf plant (Carica papaya L.) and betel leaf plant (Piper betle L.) is a plant that has long been used by the community as a traditional medicine that can cure diseases, one of which is as an antibacterial. This study aims to find out the antibacterial bland power of the combination of papaya leaf extract with betel leaves in inhibiting Staphylococcus aureus bacteria. The method used is an experimental method of combining the concentration of papaya leaf extract with betel leaves, namely K1 (100%+0%), K2 (30%+70%), K3 (40%+60%), K4 (50%+50%), K5 (60%+40%), K6 (70%+30%), K7 (0%+100%), K (-) Aquadest, K(+) Chloramfenikol, which then concentrates on testing Staphylococcus aureus bacteria with the welling method. The variables measured in this study are the diameter of the bland zone. The observations were analyzed using one away anova with a sig (0.00) < A value (0.05) continued with Tukey that showed all treatments were different. This study can be concluded that the combination of papaya leaf extract with betel leaf proved to have a bland force of antibacterial activity against Staphylococcus aureus bacteria with the largest bland zone in K2 (papaya leaf extract 30% + 70% betel leaf extract) with an average diameter of 12.17 mm. Keywords: papaya leaves, betel leaves, infections, Staphylococcus aureus, bland zone.
AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK DAUN JAMBU BIJI (Psidium guajava L.)DENGAN DAUN SIRSAK ( Annona muricata L.) TERHADAP Escherichia coli Samsuar Samsuar; Yuli Wahyu Tri Mulyani; Brigitta Saniscara R.H
JFL : Jurnal Farmasi Lampung Vol. 11 No. 2 (2022): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v11i2.806

Abstract

Infection is a type of disease that is often found in developing countries, including Indonesia. Escherichia coli is one of the most common causes of infection in society. The most common clinical symptoms in cases of this infection include watery diarrhea, abdominal cramps, low-grade fever, nausea, and malaise. Guava plants (Psidium guajava L.) and soursop plants (Annona muricata L.) are medicinal plants that are easy to find in Indonesia. Guava leaves and soursop leaves can be used as antibacterials. This study aims to determine the antibacterial activity of a combination of guava leaf extract (Psidium guajava L.) and soursop leaves (Annona muricata L.) against Escherichia coli bacteria. The method used is an experimental method of combining the concentrations of guava leaf extract and soursop leaves, namely K1 (100% + 0%), K2 (80% + 20%), K3 (60% + 40%), K4 (50% + 50% ), K5 (40%+60%), K6 (20%+80%), K7 (0%+100%), K(-) aquadest, K(+) Ciprofloxacin which was then followed by testing for Escherichia coli bacteria using the hole or well method. The variable measured in this study was the diameter of the inhibition zone formed in the combination of extracts. The results of observations were analyzed using One Way Annova with a sig value (0.000) <p value (0.050) followed by a follow-up tukey test which showed K1, K2, K3, K4, K5, K6, K7, K(-) and K(+) real different. It can be concluded from this study that the largest inhibition zone of combined extracts was found in K2 (80% guava leaf extract + 20% soursop leaf extract) with an average inhibition zone of 11.89 mm which belonged to the strong category. Inhibits the growth of E.coli bacteria. Keywords : guava leaves, soursop leaves, Escherichia coli, inhibition zone
KOMBINASI EKSTRAK DAUN BIDARADENGAN DAUN KEMANGI SEBAGAI ANTIBAKTERI TERHADAP Staphylococcus aureus DAN Escherichia coli. Muhammad Richja As seffi; Yuli Wahyu Tri Mulyani; Annisa Mulia Anasis
JFL : Jurnal Farmasi Lampung Vol. 11 No. 2 (2022): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v11i2.807

Abstract

Infectious diseases are still at the top of the list of causes of illness and death in developing countries including Indonesia, Staphylococcus aureus and Escherichia coli are commonly found around the human environment, therefore prevention is needed to reduce infection by utilizing plants that have antibacterial effects such as bidara leaves with basil leaves. This study aims to determine the antibacterial activity of the combination of bidara leaf extract and basil leaves, and to determine the best combination concentration in inhibiting the growth of Staphylococcus aureus and Escherichia coli bacteria compared to single extracts and positive controls. Using the diffusion method, the combination of dau bidara extract with basil leaves is K1 (0% + 100 %), K2 (20 + 80%), K3 (40% + 60%), K4 (50% + 50%), K5 (60 %+40%), K6 (80% + 20%), K7 (100% + 0%), K(-) Aquadest and K(+) Ampicillin. In the bacterial test (well diffusion method). The variable measured in this study was the diameter of the inhibition zone formed by the combination of extracts. Data analysis was tested using One Way Anova. The sig value for Staphylococcus aureus was 0.000≤0.05, while for Escherichia coli was 0.000≤0.05, it indicated that there was a significant difference between the test groups. The results of this study obtained the largest inhibition zone on bacteria, S. aureus, namely at K7 14.46 mm had a strong inhibitory response, while in bacteria E. Coli was found in K7 with the largest average value of 17.95 mm having a strong inhibitory response. This study can be concluded that the combination of bidara leaves and basil leaves has greater antibacterial power against Staphylococcus aureus and Escherichia coli bacteria than single extracts and positive control. Keywords: Ampicillin, antibacterial, Bidara leaves, basil leaves, diffuse
PENGARUH PERAN FARMASIS TERHADAP PENGETAHUAN PASIEN TENTANG PENATALAKSANAAN PENYAKIT DIARE DI PUSKESMAS RAWAT INAP SUKARAJA KOTA BANDAR LAMPUNG Nopiyansyah Nopiyansyah; Yuli Wahyu Tri Mulyani; Tanzilla Evitasari; Riko Herdiansah
JFL : Jurnal Farmasi Lampung Vol. 11 No. 2 (2022): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v11i2.820

Abstract

Diarrheal disease in developing countries like Indonesia is still a public health problem that can cause child death in the world. Diarrhea is a condition characterized by a person having loose stools three or more times a day. This case of diarrhea needs the role of pharmacists such as education to increase patient knowledge about the management of diarrheal diseases. Education is an activity to increase individual health knowledge regarding the management of risk factors for disease and healthy living behavior in an effort to improve public health status, prevent recurrence of disease and recover from disease. Factors that influence a knowledge that is age, education, occupation and sources of information. This study aims to determine whether there is a relationship between education and the level of patient knowledge about the management of diarrheal diseases at the Sukaraja Inpatient Health Center, Bandar Lampung City. This research is a non-experimental research with an observational analytic research design, using a one group pre-test and post-test study design that can be analyzed using the Statistical Product and Service Solutions (SPSS) method. This study was conducted for 2 months with the results of the study showing the characteristics of patients based on age, the most were 26-45 years old with 19 people (47.5%), high school education as many as 20 people (50%), and the most type of work was housewives 17 people (42.5%). The level of patient knowledge after being given an education can be seen from the Wilcoxon test with a significant value <0.005, stating that there is a relationship between education and the level of patient knowledge about the management of diarrheal diseases at the Sukaraja Inpatient Health Center, Bandar Lampung. Keywords: Diarrhea, Education, Knowledge Level.
PENINGKATAN PRODUKSI DAN PEMASARAN PADA USAHA RISOL MELALUI DIGITAL MARKETING Suhartina Suhartina; Yuli Wahyu Tri Mulyani; Eka Ubaya Taruna Rauf
Jurnal Media Pengabdian Kepada Masyarakat Vol. 1 No. 2 (2022): JM-PKM
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jmpkm.v1i2.827

Abstract

Risol is a snack that has been known for so long. As a market snack, risol sold in the form of ready-to-eat already has a relatively stable market demand. Because risol is very popular from various circles, both ordinary people and office workers, for this reason, Nasi Goreng and Gorengan SMEs are also trying to develop their talents by opening a type of business "VEGETABLE RISOL" because many of these risols imitate being partners and continue to innovate. The main problems for partners are in terms of production, management and digital marke ting. The purpose of the service activity is to increase the production and income of partners through sales promotions and implement science and technology to inspire market snack consumers to always innovate so that their products are liked by consumers. Solutions and targets by providing production support equipment needs, increasing skills, counseling on marketing strategies and simple bookkeeping as well as simulating trademark labeling and developing social media for sales promotion. The results and discussion of activities that have an important impact on the community and benefit all parties directly involved in service activities. Keywords: Digital Marketing, Production, Vegetable Risol
FRAKSI ETANOL RIMPANG KENCUR (Kaempferia Galanga L.) SEBAGAI ANTIBAKTERI TERHADAP Bacillus Subtilis dan Escherichia coli Yuli Wahyu Tri Mulyani; Annisa Mulia Anasis; Ari Yanto
JFL : Jurnal Farmasi Lampung Vol. 12 No. 1 (2023): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v12i1.995

Abstract

Abstract People were accustomed to use natural ingredients as traditional medicine because it was more economical and has little bit side effects compared with synthetic drugs. One of the herbs that has been widely known in the community as traditional medicine was the kencur rhizome. The kencur rhizome contains flavonoid and saponins which were antibacterial. The purpose of this study was to prove that there was the inhibition in ethanol fraction of kencur rhizome towards the growth of bacillus subtilis and Escherichia coli. The extraction process of kencur rhizome was carried out by maceration method used 70% ethanol solvent and continued with fractionation by using ethanol, n-hexane and chloroform solvents. Then, antibacterial test used diffusion method with concentrations of 25%, 50%, 75%, 100%, positive control of ciprofloxacin and negative control of aquadest. The test was continued by looking at the formation of inhibition zones around the diffusion and measured by using a calipers. The highest diameter of inhibition zone antibacterial activity of kencur rhizome at concentration 100% with a diameter of 22.00 mm in E. Coli and 20.00 mm for B. Subtilis, whereas positive control diameter inhibition zone of ciproflocaxin was 40.00 mm in E. Coli and 40.0 in B. Subtilis. The conclusion of this study was the ethanol fraction of kencur rhizome 100% concentration is the best concentration in the inhibition zone. Keywords: Antibacterial, Bacillus Subtilis, Escherichia coli, Kencur.
AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK DAUN KEMANGI (Ocymum x africanum L.) DENGAN DAUN PEPAYA (Carica papaya L.) TERHADAP Staphylococcus aureus Samsuar Samsuar; Yuli Wahyu Tri Mulyani; Ayu Mirda Sari
JFL : Jurnal Farmasi Lampung Vol. 12 No. 1 (2023): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v12i1.996

Abstract

Abstract Infectious diseases are one of the diseases that have suffered by many Indonesian people for a long time. S. aureus bacteria is the cause of pyogenic infections. Basil plants (Ocymum x africanum L.) and papaya plants (Carica papaya L.) can be used as antibacterial. This study aims to determine the antibacterial activity of the combination of basil and papaya leaf extracts against S. aureus bacteria. Using the Experimental Method with a combination of extract concentrations, namely K1 (0+100%), K2 (20%+80%), K3 (40%+60%), K4 (50%+50%), K5 (60%+40% ), K6 (80%+20%), K7 (100%+0%), K(-) aquadest, K(+) Oxfloxacin, followed by a test for S. aureus bacteria using the well method. The test results were analyzed using One Way Annova. with sig value (0.000) < p-value (0.05) followed by Tukey's further test which showed the combination of concentrations showed significant differences between the test groups. From this explanation, it can be concluded that the combination of basil leaf extract and papaya leaf extract can increase the inhibition zone, the largest inhibition zone is in K4 (50% basil leaf extract + 50% papaya leaf extract) the inhibitory response that appears 19.69 mm belongs to the strong category. inhibit the growth of S. aureus bacteria. Keywords: Antibacterial, basil leaf, papaya leaf, Staphylococcus aureus.
Co-Authors Amy Siska Zulyani Annisa Mulia Anasis Ari Yanto Ayu Mirda Sari Brigitta Saniscara R.H Muhammad Richja As seffi Muti Dianda Sari Nopiyansyah, Nopiyansyah Rauf, Eka Ubaya Taruna Riko Herdiansah Samsuar Samsuar Suhartina Suhartina Tanzilla Evitasari Vatiyah Hari Utami